Abstract：
BACKGROUND:Bisphosphonates (BPs) are widely used for the treatment of osteoporosis. Oversuppression of bone turnover with BPs may paradoxically limit the reserve capacity of bone to heal. The aim of this review was to study the predisposition of some patients to delayed/non-union of upper limb fractures associated with BPs and give recommendations on how they should be treated. METHODS:A systematic search of two electronic databases was conducted to identify relevant studies for inclusion. All relevant studies found were included and assessed through methodology criteria predetermined by two independent reviewers. RESULTS:Six papers comprising of three case reports, one nested case control study, one restrospective review and one randomized clinical trial were used. In comparative studies of pre-fracture BP use, a 6-day delay in average healing times was reported among BP users. There was no elevation in risk of non-union. Post-fracture BP use was associated with an approximate doubling of the risk of non-union. Timing of BP therapy initiation following a fracture was not associated with a difference in healing times. An atypical ulna fracture treated conservatively resulted in non-union, there was no effect of type of surgical treatment on distal radius fracture healing and there was insufficient evidence to comment on humeral fracture treatment. CONCLUSIONS:Differences in union time between BP users and non-users are not significant enough to change current practice patterns and do not outweigh the benefits of BP therapy. There is no evidence to encourage early surgical management of BP-related upper limb fractures.
journal_name
ANZ J Surgjournal_title
ANZ journal of surgeryauthors
Ng AJ,Yue B,Joseph S,Richardson Mdoi
10.1111/ans.12536subject
Has Abstractpub_date
2014-04-01 00:00:00pages
218-24issue
4eissn
1445-1433issn
1445-2197journal_volume
84pub_type
杂志文章,评审abstract：BACKGROUND:Anticoagulation treatment in the community is common. This investigation was undertaken to determine the frequency of patient surgical admission with conditions associated with over-anticoagulation in the community and the surgical resource required to effectively and safely manage these patients acutely. M...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
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abstract：:Chronic constipation is a common condition in both adults and children. Children with chronic constipation frequently have symptoms that continue into adulthood. In the second part of the review we describe advances in the identification of abnormalities in the control of motility. The role of neurotransmitters in bot...
journal_title：ANZ journal of surgery
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abstract：:Susan Nixon died in 1881 following a surgical error. Her surgeon, Dr W. E. Warren, excised a normal 7-month gravid uterus under the misapprehension that he was removing a tubular pregnancy. It is believed that Mrs Nixon was the first woman in Australia to have an abdominal hysterectomy and the second to have a live Ca...
journal_title：ANZ journal of surgery
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abstract：BACKGROUND:Readability indices have been developed based on sentence length and the use of long words. One such measure is the Reading Ease Scale developed by Rudolf Flesch. Texts that are easy to read have high scores: texts with scores below 30 are similar to legal contracts. This study uses Flesch scores to evaluate...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2006.03651.x
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journal_title：ANZ journal of surgery
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abstract：INTRODUCTION:Lymph node metastases represent a diagnostic and management challenge in patients with disseminated medullary thyroid carcinoma (MTC). Our understanding of microRNA (miRNA) profiles of metastatic disease also remains limited and may unveil novel therapeutic strategies for these patients. METHODS:MTC patie...
journal_title：ANZ journal of surgery
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journal_title：ANZ journal of surgery
pub_type： 杂志文章
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abstract：:Bleeding related to rectal varices associated with portal hypertension is rare but life-threatening, and requires prompt treatment. We reviewed the literature for patients with this complex presentation and current recommendations, and commented on a case at our institution of a 68-year-old man with Child-Pugh B alcoh...
journal_title：ANZ journal of surgery
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journal_title：ANZ journal of surgery
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journal_title：ANZ journal of surgery
pub_type： 杂志文章
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abstract：BACKGROUND:Laying open (deroofing, not excision) and curettage of the sinus is a minimally invasive procedure to treat pilonidal disease. A consensus on its efficacy and outcomes has not been reached. We reviewed and meta-analysed the efficacy of this procedure. METHODS:PubMed, Medline, Scopus, Ovid, Cochrane central ...
journal_title：ANZ journal of surgery
pub_type： 杂志文章,meta分析,评审
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更新日期：2016-01-01 00:00:00
abstract：BACKGROUND:Hepatic haemangiomas are congenital vascular malformations. They are the most common benign tumours of the liver and are often asymptomatic. Spontaneous or traumatic rupture, intratumoral bleeding, consumption coagulopathy and rapid growth are the mandatory surgical indications. We present our experience ove...
journal_title：ANZ journal of surgery
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doi：10.1111/j.1445-2197.2006.03869.x
更新日期：2006-09-01 00:00:00
abstract：BACKGROUND:Tibial-plateau fractures with depressed osteochondral fragments have a high incidence of articular subsidence post reduction. Locking plates aim to prevent this via 'raft' screws below the subchondral bone. However, differences in plate design and patient anatomy result in variability of screw position in re...
journal_title：ANZ journal of surgery
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abstract：BACKGROUND:Acute pancreatitis (AP) is a common acute surgical presentation with evidence-based guidelines for early management. The aim of this study was to assess the compliance to the published guidelines in patients presenting with AP in Western Sydney. METHODS:A retrospective case note audit was conducted for all ...
journal_title：ANZ journal of surgery
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更新日期：2017-10-01 00:00:00
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journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2007.04221.x
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abstract：BACKGROUND:Improved life-expectancies have seen increased rates of older patients undergoing surgery worldwide. These patients are at increased risk of post-operative complications. Australian evidence is limited regarding the association between age and post-operative outcomes, especially rapid response calls (RRCs) a...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/ans.14433
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abstract：BACKGROUND:Delayed coloanal anastomosis (DCAA) may be used in patients with complex rectal conditions, such as chronic pelvic sepsis, low recto-vaginal and recto-vesical fistula; however, limited data are available. The aim is to report the morbidity and functional results of DCAA in redo rectal surgery. METHODS:All p...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
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journal_title：ANZ journal of surgery
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journal_title：ANZ journal of surgery
pub_type： 杂志文章
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journal_title：ANZ journal of surgery
pub_type： 杂志文章
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journal_title：ANZ journal of surgery
pub_type： 杂志文章
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更新日期：2004-09-01 00:00:00
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更新日期：2017-03-01 00:00:00
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journal_title：ANZ journal of surgery
pub_type： 临床试验,杂志文章
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更新日期：2013-10-01 00:00:00
abstract：INTRODUCTION:Sigmoid volvulus typically occurs in older patients who have multiple co-morbidities. Therefore, often, a conservative approach to management is chosen. However, there is little data on long-term outcomes of this approach in Australasia. The aim of this study was to review the recurrence and mortality outc...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2012.06182.x
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND:Trauma teams have been associated with improved survival probability of paediatric trauma patients. The present study seeks to estimate the use of trauma teams in Australian paediatric tertiary referral centres and describe their medical composition, leadership and criteria for activation. METHODS:Australia...
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pub_type： 杂志文章
doi：10.1111/j.1445-1433.2004.03213.x
更新日期：2004-11-01 00:00:00
abstract：BACKGROUND:Acute diverticulitis of the caecum and ascending colon is uncommon. Controversies abound as regards the optimal surgical treatment, ranging from appendectomy, diverticulectomy to right hemicolectomy. The aim of the present paper was to review treatment strategy followed by a critical appraisal. METHODS:The ...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
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更新日期：2001-11-01 00:00:00
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journal_title：ANZ journal of surgery
pub_type： 杂志文章
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更新日期：2019-05-01 00:00:00
abstract：BACKGROUND:In elective colorectal resections, the patient's preoperative social situation may play a significant role in delaying their discharge from hospital. The aim of this study was to identify which preoperative factors are associated with non-medical reasons for a delay in discharge and prolonged length of stay ...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
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