Paediatric constipation for adult surgeons - article 2: new microscopic abnormalities and therapies.

Abstract:

:Chronic constipation is a common condition in both adults and children. Children with chronic constipation frequently have symptoms that continue into adulthood. In the second part of the review we describe advances in the identification of abnormalities in the control of motility. The role of neurotransmitters in both paediatric and adult constipation is examined and the radical rethink of colonic dysmotility caused by the re-emergence of interstitial cells of Cajal is discussed. The recognition of chronic constipation as an heterogenous condition has led to the introduction of new therapies. Antegrade washouts through appendix stomas and an exciting new treatment with electrical interferential therapy may, in the future, result in a less invasive approach to the management of chronic constipation. An improved understanding of the assessment and management of chronic constipation in childhood is also likely to reduce the frequency and morbidity of chronic constipation in adults.

journal_name

ANZ J Surg

journal_title

ANZ journal of surgery

authors

King SK,Sutcliffe JR,Hutson JM,Southwell BR

doi

10.1111/j.1445-1433.2004.03202.x

keywords:

subject

Has Abstract

pub_date

2004-10-01 00:00:00

pages

890-4

issue

10

eissn

1445-1433

issn

1445-2197

pii

ANS3202

journal_volume

74

pub_type

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