Abstract:
BACKGROUND:Although several growth factors are known to be essential for liver regeneration, the role of gastrin remains controversial. METHODS:Liver regeneration was examined in wild-type (WT) and gastrin-deficient (gastrin KO) mice at days 2 and 10 after partial (40%) hepatectomy by measurement of liver weight. Hepatocyte proliferation and circulating gastrin concentrations were measured at the same time points by immunohistochemistry and radioimmunoassay, respectively. RESULTS:There was no significant difference in the rate of liver regeneration between gastrin KO and WT mice. Hepatocyte proliferation in both groups was increased at day 2 but had returned to baseline values by day 10. At day 2, hepatocyte proliferation in the gastrin KO mice was significantly higher than in WT animals, whereas at day 10, proliferation was significantly greater in the WT mice. The circulating gastrin concentration in the WT mice was significantly lower at day 10 than in unoperated WT animals. CONCLUSION:This study suggests that gastrin is not essential for liver regeneration after partial hepatectomy.
journal_name
ANZ J Surgjournal_title
ANZ journal of surgeryauthors
Dizdarevic A,Harun N,Malcontenti-Wilson C,Shulkes A,Christophi C,Baldwin GSdoi
10.1111/j.1445-2197.2007.04360.xsubject
Has Abstractpub_date
2008-01-01 00:00:00pages
68-71issue
1-2eissn
1445-1433issn
1445-2197pii
ANS4360journal_volume
78pub_type
杂志文章abstract::Thirty-eight patients with mammary gland tuberculosis were evaluated over a 5-year period presenting to the surgical unit of our institution. Unilateral involvement of the breast in a woman presenting at an average age of 29 years was the commonest observation. A lump in the breast with or without discharging sinuses ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2006.03692.x
更新日期:2006-04-01 00:00:00
abstract:BACKGROUND:The unrivalled conquests of Genghis Khan (CE c.1162-1227) led to the establishment of the Greater Mongolian Empire. By 1279, the Mongol dynasty controlled a vast Empire which, for the first time in history, unified Europe and China via the famous Silk Road. The ensuing century of peace and stability is refer...
journal_title:ANZ journal of surgery
pub_type: 历史文章,杂志文章
doi:10.1111/ans.13813
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:The Royal Australasian College of Surgeons recommends minimum operative and endoscopy training requirements for advanced trainees in general surgery. This study examines the influences of trainee seniority, geographical location of surgical rotation, and surgeons' remuneration arrangements on the operative a...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1445-2197.2003.t01-1-.x
更新日期:2003-12-01 00:00:00
abstract:BACKGROUND:Patients taking warfarin are often given interim anticoagulation in the perioperative period. Institutional guidelines that use low-molecular-weight heparin (LMWH) 'bridging' while the international normalized ratio (INR) is sub-therapeutic are often based on the American College of Chest Physicians Anticoag...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.12070
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND:Acute respiratory distress syndrome (ARDS) is a major contributor to respiratory morbidity and mortality after oesophagectomy. Several pre-, intra- and post-operative factors are thought to predispose to its development in the post-oesophagectomy period. The aim of this study was to determine factors predisp...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1445-2197.2010.05598.x
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:Various treatment measures have been described in achieving splenic preservation following splenic injury. We describe an additional measure in achieving haemostasis during mesh splenorrhaphy. METHODS:Oxycel (BD, Franklin Lakes, NJ, USA) (topical haemostatic agent composed of oxidized cellulose) is sutured ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2004.03065.x
更新日期:2004-07-01 00:00:00
abstract:BACKGROUND:Chemical burns account for relatively few admissions to a burns unit. These injuries, however, deserve separate consideration because of their ability to cause continuing tissue destruction, their potential to cause systemic toxicity and the value of early treatment with copious lavage. Widespread inexperien...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1445-2197.2003.02617.x
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:The central venous access port device (CVAPD) provides reliable vascular access and is used for delivery of fluids and for obtaining blood samples. However, it can carry some intra- and post-operative complications such as thrombosis, pneumothorax, catheter fracture and port malposition. This article describ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.13338
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Sore throat is not an uncommon complaint following general anaesthesia (GA) with endotracheal intubation. It has been a source of considerable discomfort particularly in those patients who had thyroid surgery. Driven by the increased number of patients with post-intubation sore throat following thyroid surge...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1445-1433.2001.02230.x
更新日期:2001-11-01 00:00:00
abstract:BACKGROUND:Choosing Wisely Australia is an initiative aimed at reducing the incidence of unnecessary investigations. This study is an audit of Northern Health's adherence to two Choosing Wisely recommendations in the context of inguinal hernia repair. Recommendation 1: Avoid routinely performing pre-operative investiga...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.15495
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Pulmonary metastasectomy has become a popular procedure for patients with pulmonary metastases. It can be achieved via the traditional open thoracotomy or the more recently developed video-assisted thoracoscopic surgery (VATS). However, there has been much debate as to which approach is better in terms of de...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/ans.12925
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:The aim of this study was to assess the value of fine-needle aspiration cytology (FNAC) as a preoperative evaluation for parotid tumours. METHODS:Prospectively collected data on 77 patients, collected on a parotid database, were retrospectively analysed. Preoperative investigations were carried out and cyto...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2008.04651.x
更新日期:2008-09-01 00:00:00
abstract:BACKGROUND:Limited health resources necessitate prioritization for access to elective cholecystectomy in New Zealand. We aimed to develop and validate a patient questionnaire for determining the effect of gallstone disease on quality of life (QOL) and evaluate its potential role in appraising prioritization and outcome...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2006.03777.x
更新日期:2006-07-01 00:00:00
abstract:BACKGROUND:Carbon dioxide (CO2) insufflation during colonoscopy was reported to reduce pain, but data are limited. The objective of this randomized controlled trial was to assess the effect of CO2 insufflation on pain during and after colonoscopy. METHODS:Patients were randomized into CO2 insufflation (CO2i) or air in...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1445-2197.2008.04683.x
更新日期:2008-10-01 00:00:00
abstract:BACKGROUND:Idiopathic megacolon (IMC) is an uncommon disease in adults. To date, only a few laparoscopic experiences and functional outcomes of IMC have been reported. This study was to retrospectively analyse our 12 year surgical experience and functional outcomes in adult patients with IMC. METHODS:A 12-year retrosp...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.15868
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Subglottic hemangiomas (SGH) are a rare tumour, often associated with significant airway obstruction in infants. Current treatment options, while effective, often expose the infant to potential complications. Emerging evidence suggests a role for the beta blocker propranolol in the initial management of SGH....
journal_title:ANZ journal of surgery
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1445-2197.2010.05643.x
更新日期:2011-06-01 00:00:00
abstract::Constipation is very common in all age groups and can be resistant to standard therapies, producing chronic morbidity. Childhood onset constipation frequently produces symptoms that persist into adulthood. Recent advances have been made in the diagnosis and treatment of childhood constipation that could have applicati...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/j.1445-1433.2004.03149.x
更新日期:2004-09-01 00:00:00
abstract::In the early years of the introduction of Christianity into China, one American medical missionary distinguished himself by his kindness and generosity towards the Chinese people, and also by his surgical prowess. Peter Parker (1804-1888) was a graduate from the Yale University Medical School and was also an ordained ...
journal_title:ANZ journal of surgery
pub_type: 传,历史文章,杂志文章
doi:10.1111/ans.12402
更新日期:2013-12-01 00:00:00
abstract:BACKGROUND:To examine any geographical variation in the management of urolithiasis amongst the Australian states and territories. METHODS:Retrospective study with data obtained from the Medicare Australia database, the Royal Australasian College of Surgeons and the Urological Society of Australia and New Zealand. RES...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.13646
更新日期:2017-06-01 00:00:00
abstract::The Royal Colleges of Surgeons and Surgical Specialty Associations in the UK have introduced competence-based syllabi and curricula for surgical training. The syllabi of the Intercollegiate Surgical Curriculum Programme (ISCP) and Orthopaedic Curriculum and Assessment Programme (OCAP) define the core competencies, tha...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2008.04832.x
更新日期:2009-03-01 00:00:00
abstract:BACKGROUND:The purpose of the present study was to examine the effects of demographic, locational and social disadvantage and the possession of private health insurance in Western Australia on the likelihood of women with breast cancer receiving breast-conserving surgery rather than mastectomy. METHODS:The WA Record L...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-1433.2004.03020.x
更新日期:2004-06-01 00:00:00
abstract:INTRODUCTION:Lymph node metastases represent a diagnostic and management challenge in patients with disseminated medullary thyroid carcinoma (MTC). Our understanding of microRNA (miRNA) profiles of metastatic disease also remains limited and may unveil novel therapeutic strategies for these patients. METHODS:MTC patie...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2012.06291.x
更新日期:2014-04-01 00:00:00
abstract::Carpal tunnel syndrome is a common condition affecting 1% of the population. Open carpal tunnel release is the most commonly performed procedure for this condition. About 70-90% of patients have good to excellent long-term outcomes with open carpal tunnel release. The remainder have poor outcomes. An understanding of ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/j.1445-2197.2009.05175.x
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:To formulate clinical pathways for identifying clinically significant prostate cancer (csPC) and avoiding insignificant prostate cancer (isPC) in those without suspicious regions of interest on multi-parametric magnetic resonance imaging (mpMRI) of the prostate. METHODS:A retrospective review identified pat...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.16583
更新日期:2021-01-21 00:00:00
abstract:BACKGROUND:There is conflicting evidence regarding the oncological impact of anastomotic leak following colorectal cancer surgery. This study aims to test the hypothesis that anastomotic leak is independently associated with local recurrence and overall and cancer-specific survival. METHODS:Analysis of prospectively c...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.13648
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:The isolated limb infusion (ILI) technique is a simpler and less invasive alternative to isolated limb perfusion, which allows regional administration of high-dose chemotherapy to patients with advanced melanoma and other malignancies restricted to a limb. METHODS:Patients from two institutions, treated by ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1445-2197.2012.06249.x
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND:Surgical approach into the fissural parenchyma may be an important and modifiable factor for the prevention of air leak after anatomical lung resections. Fissureless fissure-last technique has been described as useful technique to reduce air leak, yet in video-assisted thoracoscopic surgery (VATS) data are l...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.13884
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Infection with multidrug-resistant (MDR) Gram-negative organisms leads to poorer outcomes in the critically ill burn patient. The aim of this study was to identify the risk factors for MDR Gram-negative pathogen infection in critically ill burn patients admitted to a major tertiary referral intensive care un...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.14144
更新日期:2018-05-01 00:00:00
abstract::In his position as curator of the Cowlishaw collection of historical medical books in the Library of the College, Kenneth Russell prepared the definitive catalogue of the collection. This catalogue is comprehensive and for almost all entries there is an annotation that demonstrates his meticulous attention to detail a...
journal_title:ANZ journal of surgery
pub_type: 传,历史文章
doi:10.1046/j.1445-1433.2003.02645.x
更新日期:2003-07-01 00:00:00
abstract:BACKGROUND:The volume of orthopaedic literature is increasing exponentially, becoming more widely scattered among journals. The rate of increase in orthopaedics is greater than other specialties. We aimed to identify the number of different journals an orthopaedic surgeon would need to read to stay up-to-date with curr...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.12902
更新日期:2015-06-01 00:00:00