Abstract:
BACKGROUND:Although several growth factors are known to be essential for liver regeneration, the role of gastrin remains controversial. METHODS:Liver regeneration was examined in wild-type (WT) and gastrin-deficient (gastrin KO) mice at days 2 and 10 after partial (40%) hepatectomy by measurement of liver weight. Hepatocyte proliferation and circulating gastrin concentrations were measured at the same time points by immunohistochemistry and radioimmunoassay, respectively. RESULTS:There was no significant difference in the rate of liver regeneration between gastrin KO and WT mice. Hepatocyte proliferation in both groups was increased at day 2 but had returned to baseline values by day 10. At day 2, hepatocyte proliferation in the gastrin KO mice was significantly higher than in WT animals, whereas at day 10, proliferation was significantly greater in the WT mice. The circulating gastrin concentration in the WT mice was significantly lower at day 10 than in unoperated WT animals. CONCLUSION:This study suggests that gastrin is not essential for liver regeneration after partial hepatectomy.
journal_name
ANZ J Surgjournal_title
ANZ journal of surgeryauthors
Dizdarevic A,Harun N,Malcontenti-Wilson C,Shulkes A,Christophi C,Baldwin GSdoi
10.1111/j.1445-2197.2007.04360.xsubject
Has Abstractpub_date
2008-01-01 00:00:00pages
68-71issue
1-2eissn
1445-1433issn
1445-2197pii
ANS4360journal_volume
78pub_type
杂志文章abstract::Mucinous appendiceal neoplasms (MANs) are rare tumours and the primary cause of pseudomyxoma peritonei. These tumours have a much more benign course than typical colorectal cancers, generally growing for many years before giving any clinical signs. The spectrum of presentations, tumour stages and the underlying cytolo...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/ans.16185
更新日期:2020-08-05 00:00:00
abstract:BACKGROUND:This study documents the anatomy of the pudendal nerve, which has a major role in maintaining faecal continence. Unexpected faecal incontinence can develop following perineal surgery even when the anal sphincters are not damaged. In addition, injury to the pudendal nerve might be encountered during pelvic pr...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1445-1433.2003.02885.x
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:The present paper examines the local recurrence rate following surgical treatment for carcinoma of the lower rectum with principally blunt dissection directed at tumour-specific mesorectal excision (including total mesorectal excision when appropriate). METHODS:During the period April 1987-December 1999, 12...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-1433.2004.03136.x
更新日期:2004-09-01 00:00:00
abstract:BACKGROUND:The aim of this review is to explain the components of emotional intelligence (EI) and explore the benefits within today's health care system with an emphasis on surgery. EI is a person's ability to understand their own emotions and those of the individuals they interact with. Higher individual EI has multip...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/ans.15671
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Laparoscopic cholecystectomy (LC) is often performed during the index admission after emergency presentation for acute biliary pain. Many patients have acute cholecystitis (AC) that may increase operative difficulty and complications. Our primary aim was to assess the validity of Tokyo Guidelines (TG18) for ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.15603
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Treatment decisions for metastatic spine disease are complex and depend on prognosis. Four prognostic systems in use are the Oswestry Risk Index, modified Bauer score (MBS), van der Linden score and New England Spinal Metastasis Score (NESMS). We aimed to determine the performance of these scoring systems in...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.15821
更新日期:2020-06-01 00:00:00
abstract:INTRODUCTION:The purpose of the present paper is to provide geographically representative information on the presentation, treatment and complications of human bites of the hand in Australia. METHODS:A 5-year retrospective study was undertaken of patients treated at Royal Hobart Hospital for human bites of the hand. T...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1440-1622.2001.02162.x
更新日期:2001-08-01 00:00:00
abstract:BACKGROUND:Surgeons are noticing increasing numbers of cholecystectomy waiting list patients presenting with complications of their gallstones. In this study, we analysed the outcome of these to ascertain natural history and outcome. METHODS:Data for 5298 waiting list patients in Western Australia, from 1999 to 2006, ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2010.05428.x
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:This study reviews the functional outcome and satisfaction of patients after subtotal or total colectomy (STTC). METHODS:A retrospective review of patients who underwent STTC between June 1999 and September 2003 was performed. A standardized questionnaire was formulated and phone interviews were conducted wi...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2005.03552.x
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND:Few studies have investigated the risk factors associated with developing intestinal stoma complications using appropriate multivariable methods. We aimed to determine the prevalence of, and risk factors for, stomal complications. METHODS:A retrospective, case-control methodology was used to investigate 12 ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.13397
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Evidence suggests that there is considerable variation in the types of procedures used to treat cancer. This variation may result in suboptimal or cost-ineffective care. The present study examined the variation in surgical treatment of melanoma before the establishment of a Melanoma Network that could promot...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2006.03717.x
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:In the present paper we describe the presentation and management of ductal carcinoma in situ (DCIS) of the breast in women in Australia in 1995. This representative, national data set provides a historical comparator for studies examining DCIS management that follow. METHODS:Surgeons identified by populatio...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1445-2197.2002.02532.x
更新日期:2002-10-01 00:00:00
abstract:BACKGROUND:Many haemodialysis patients are unable to have or maintain distal upper limb arteriovenous (AV) fistulas because of inadequate veins or arteries and therefore require more proximal access. We have reviewed our experience with a two-stage brachiobasilic AV haemodialysis fistula fashioned in the arm. METHODS:...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2006.03996.x
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND:Previous publications have implied that the keystone flap provides mechanical benefits compared to primary closure. This has not been objectively demonstrated. METHODS:Elliptical defects were created in 'fresh-frozen' cadaveric specimens. Two approaches were used to investigate the potential mechanical bene...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.14163
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:For patients presenting with symptomatic internal carotid artery stenosis, carotid endarterectomy (CEA) surgery is recommended to be performed generally within a 48-hr to 14-day window. This study aimed to assess timeliness of delivery, and outcomes, of CEA surgery in a tertiary vascular centre. METHOD:Pati...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.15757
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Low back pain (LBP) is a common occupational musculoskeletal complaint among health professionals. No research has quantified lumbar movement patterns in the surgical workplace, identifying 'at risk' behaviours with objective measures. This project aimed to identify lumbar movement patterns and change in LBP...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/ans.14812
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Single-incision laparoscopic cholecystectomy (SILC) is a common procedure performed worldwide. In this study, we evaluated the safety and efficacy of SILC for acute cholecystitis. METHODS:Patients who underwent SILC between September 2012 and December 2016 were retrospectively enrolled and divided into acut...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.14246
更新日期:2018-07-01 00:00:00
abstract::Total thyroidectomy is the treatment of choice for clinically significant papillary thyroid cancer (PTC); however, 10-15% develop palpable local recurrence in the cervical lymph nodes. Metastases in the cervical lymph nodes account for 75% of loco-regional recurrence and up to 50% of these patients eventually die of t...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2007.04019.x
更新日期:2007-04-01 00:00:00
abstract:EARLY LIFE:George Hogarth Pringle, later an associate of Joseph Lister, was born in Kintail, Scotland in 1830. In 1854, he worked as a dresser at the Royal Infirmary, Edinburgh with Joseph Lister. After serving in the Crimean War, he settled in New South Wales and began practice in Parramatta. PRINGLE AND ANTISEPTIC S...
journal_title:ANZ journal of surgery
pub_type: 传,历史文章,杂志文章
doi:10.1111/ans.15569
更新日期:2019-12-01 00:00:00
abstract::In the seventeenth century, Holland and the allied provinces of the northern Netherlands won final independence from their Spanish overlords and formed a worldwide economic empire. Dutch ships dominated the seas from the Caribbean to Japan and reconnoitred the coasts of Australia and New Zealand. Dutch society was cos...
journal_title:ANZ journal of surgery
pub_type: 传,历史文章
doi:10.1111/j.1445-2197.2007.04327.x
更新日期:2007-12-01 00:00:00
abstract:BACKGROUND:Patients taking warfarin are often given interim anticoagulation in the perioperative period. Institutional guidelines that use low-molecular-weight heparin (LMWH) 'bridging' while the international normalized ratio (INR) is sub-therapeutic are often based on the American College of Chest Physicians Anticoag...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.12070
更新日期:2016-03-01 00:00:00
abstract::Currently in Australasia, concomitant cholecystolithiasis and choledocholithiasis are usually managed with two procedures: laparoscopic cholecystectomy (LC) and pre or postoperative endoscopic retrograde cholangiopancreatography (ERCP). This approach exposes the patient to the risk of complications from the common bil...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/ans.13676
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:The aim of this study was to develop a points-based approach to prioritize patients for elective transurethral resection of the prostate and to determine the relative contributions that clinical and psychosocial characteristics should make to a measurement of urgency for surgery. Another objective was to mea...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2006.03988.x
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND:Acute pancreatitis (AP) is a common acute surgical presentation with evidence-based guidelines for early management. The aim of this study was to assess the compliance to the published guidelines in patients presenting with AP in Western Sydney. METHODS:A retrospective case note audit was conducted for all ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.13330
更新日期:2017-10-01 00:00:00
abstract::Both chemical and mechanical methods of prophylaxis have reduced the incidence of thromboembolic complications following total knee replacement (TKR). Only a few studies have shown that mobilization on the first post-operative day further reduces the incidence of thromboembolic phenomena. We conducted a prospective st...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2009.04982.x
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND:Venous duplex ultrasound scanning (VDUS) has been shown to be an accurate non-invasive means to diagnose symptomatic deep venous thrombosis (DVT). The aim of our study was to determine whether bilateral VDUS is necessary in patients who present with symptoms of DVT. METHODS:We retrospectively reviewed the r...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-1433.2004.03187.x
更新日期:2004-10-01 00:00:00
abstract:BACKGROUND:Some authors, either with anatomical studies or Doppler laser flowmetric investigations have shown the blood flow to the posterior midline of the anus to be potentially deficient. This relative local ischaemia might explain pathogenesis of anal fissure, which is often located posteriorly. The aim of this stu...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.15143
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:A survey conducted in 1992 found that New Zealand orthopaedic surgeons relied on non-pharmacological methods of deep vein thrombosis prevention in most arthroplasty patients and almost all hip fracture patients. This survey was repeated in 1999 to ascertain whether this pattern of use had changed. METHODS:A...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1445-2197.2002.02404.x
更新日期:2002-05-01 00:00:00
abstract:BACKGROUND:Acute appendicitis (AA) is a common indication for urgent abdominal surgery. CA-125 glycoprotein antigen is a non-specific marker for epithelial ovarian cancer; CA-125 serum levels also increased in the conditions of peritoneal inflammation. The aim of this study was to examine the correlation between serum ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.13128
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:A reversal of Hartmann's procedure can be performed using either a laparoscopic or open approach. However, laparoscopic reversal (LR) of Hartmann's procedure is challenging. This study was designed to compare the results between open and laparoscopic approaches. METHODS:This was a retrospective study of pro...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.13979
更新日期:2018-05-01 00:00:00