Microsatellite instability typing in serum and tissue of patients with colorectal cancer: comparing real time PCR with hybridization probe and high-performance liquid chromatography.

abstract：:This meta-analysis was performed to evaluate the relationships between promoter DNA methylation in tumor suppressor gene p16 and gastric carcinogenesis. The PubMed, CISCOM, CINAHL, Web of Science, Google Scholar, EBSCO, Cochrane Library and CBM databases were searched for relevant articles published before November 1s...

journal_title：Molecular biology reports

authors： Wang HL,Zhou PY,Liu P,Zhang Y

更新日期：2014-07-01 00:00:00

abstract：:Membrane-bound ribosomes were isolated from a post-mitochondrial supernatant fraction of mouse liver homogenate by sedimentation in a sucrose density gradient, Loose ribosomes were released from the membrane fragments with 0.5 M KCl, while tight bound ribosomes were not released. After purification of the loose and ti...

journal_title：Molecular biology reports

authors： Hoffman WL,Dowben RM

更新日期：1980-07-31 00:00:00

abstract：:Substantial epidemiological studies have shown an association of obesity with the common gynecological malignancy, endometrial cancer. The relevant interactions and contribution of estradiol and the adipose cytokine, leptin, in endometrial lesions are not completely understood. Suitable animal models to understand the...

journal_title：Molecular biology reports

authors： Shetty A,Venkatesh T,Tsutsumi R,Suresh PS

更新日期：2020-01-01 00:00:00

abstract：:The q11.2 region on chromosome 22 contains numerous low-copy repeats that lead to deleted or duplicated regions in the chromosome, thereby resulting in different syndromes characterized by intellectual disabilities or congenital anomalies. The association between patient phenotypes and 22q11.2 copy number abnormalitie...

journal_title：Molecular biology reports

authors： Cai M,Lin N,Su L,Wu X,Xie X,Li Y,Lin Y,Huang H,Xu L

更新日期：2020-10-01 00:00:00

abstract：:The aim of this study was to determine whether the Fcγ receptors (FCGRs) polymorphisms confer susceptibility to periodontitis in ethnically different populations. We did a literature search using PubMed and Embase, and conducted a meta-analysis on the associations between the FCGR2A H131R (rs1801274), FCGR3A F158V (rs...

journal_title：Molecular biology reports

authors： Song GG,Lee YH

更新日期：2013-08-01 00:00:00

abstract：:Spata34 is a testis-specific-expressed gene which exerts diverse functions in testis development. This study intends to examine the expression profiles of Spata34 in postnatal rat testis, and explore its potential roles in cell proliferation in vitro. We found that the mRNA and protein expression levels of Spata34 wer...

journal_title：Molecular biology reports

authors： Nie D,Li H,Liu Y,Liao Z

更新日期：2018-12-01 00:00:00

abstract：:Etiological factors for coronary artery disease (CAD) involve a wide range of gene and environmental interactions. One of the systems being implicated in the pathophysiology of CAD is the renin-angiotensin system (RAS). However, the genetic polymorphisms of this system have not been widely studied in Iranian patients ...

journal_title：Molecular biology reports

authors： Firouzabadi N,Tajik N,Bahramali E,Bakhshandeh H,Maadani M,Shafiei M

更新日期：2013-08-01 00:00:00

abstract：:Growth-regulating factor (GRF) is an important protein in GA-mediated response, with key roles in plant growth and development. However, it is not known whether or how the GRF proteins in citrus to regulate organ size. In this study, nine citrus GRF genes (CsGRF1-9) were validated from the 'Anliu' sweet orange (AL, Ci...

journal_title：Molecular biology reports

authors： Liu X,Guo LX,Jin LF,Liu YZ,Liu T,Fan YH,Peng SA

更新日期：2016-10-01 00:00:00

abstract：:Statins have shown pleiotropic effects, many of them independent of their impact on lipids. Angiogenesis can be beneficial in the acute myocardial infarction to improve circulation. However, it also can be harmful due to worsening of atherosclerosis. Here, we established a new minimal invasive rabbit model to study is...

journal_title：Molecular biology reports

authors： Shen W,Shi HM,Fan WH,Luo XP,Jin B,Li Y

更新日期：2011-08-01 00:00:00

abstract：:Helicteres hirsuta Lour. (H. hirsuta) has been considered as a herbal medicine for the treatment of malaria and diabetes but limited studies have been conducted on its anticancer and antibacterial properties. In this study, the in vitro antibacterial and anticancer properties of the leaf and stem extracts and their tw...

journal_title：Molecular biology reports

authors： Pham HNT,Sakoff JA,Bond DR,Vuong QV,Bowyer MC,Scarlett CJ

更新日期：2018-12-01 00:00:00

abstract：:The studies conducted aimed at evaluating the genetic diversity within and between varieties of conservative flocks of geese, using the polymorphism of 14 microsatellite sequences. The experimental material included conservative flocks of geese the following indigenous breeds and varieties kept in Poland: Kielecka (Ki...

journal_title：Molecular biology reports

authors： Parada R,Książkiewicz J,Kawka M,Jaszczak K

更新日期：2012-05-01 00:00:00

abstract：:The epidermal growth factor receptor (EGFR) is an important receptor tyrosine kinase member in animals, which plays versatile functions in development, growth, tissue regeneration etc. Current knowledge on EGFR is poor in bivalve mollusks. In this study, we cloned and analyzed an EGFR gene from the Pacific oyster Cras...

journal_title：Molecular biology reports

authors： Sun L,Huan P,Wang H,Liu F,Liu B

更新日期：2014-05-01 00:00:00

abstract：:The suppressors of cytokine signaling (SOCS) proteins are originally identified as negative regulators of cytokine-activated Janus kinase/signal transducers and activators of transcription signaling pathway, but increasing evidence reveals that SOCS proteins play an important role in the development of type 2 diabetes...

journal_title：Molecular biology reports

authors： Feng X,Tang H,Leng J,Jiang Q

更新日期：2014-01-01 00:00:00

abstract：:Blood and liver from curimbata (Prochilodus lineatus) acclimated at pH 4.5, 7.0 and 8.0 and at 20 and 30 °C were exposed in vitro to different concentrations of copper (Cu): 98 ± 0.8 μg Cu L-1 at pH 4.5 and 16 ± 0.2 μg Cu L-1 at pH 8.0 at 20 °C; 88 ± 0.8 μg Cu L-1 at pH 4.5 and 14 ± 0.5 μg Cu L-1 at pH 8.0 at 30 °C an...

journal_title：Molecular biology reports

authors： Dos Santos Carvalho C,Fernandes MN

更新日期：2019-10-01 00:00:00

abstract：:Hepatitis B virus X protein (HBx) is closely involved in the development of hepatocellular carcinoma (HCC). Tumor suppressor p53 was reported to induce HBx degradation and repress its oncogenic function recently, but the molecular mechanism is unknown. In this study, we attempted to identify the underlying mechanism. ...

journal_title：Molecular biology reports

authors： Xian L,Zhao J,Wang J,Fang Z,Peng B,Wang W,Ji X,Yu L

更新日期：2010-07-01 00:00:00

abstract：:One of the major limitations when attempting to obtain detailed biochemical, biophysical and immunological characterization of plant DNA mismatch repair proteins is their extremely low abundance in vivo under normal growth conditions. An initial analysis of PMS1 transcript level in various Arabidopsis thaliana tissues...

journal_title：Molecular biology reports

authors： Galles C,Gomez RL,Spampinato CP

更新日期：2011-02-01 00:00:00

abstract：:Trichoderma asperellum, a filamentous soil fungus, is an effective biocontrol agent against many fungal plant pathogenic species. In the present study, we investigated the biological control properties of the strain T. asperellum T4. T. asperellum fermentation products significantly decreased the ability of Rhizoctoni...

journal_title：Molecular biology reports

authors： Liu Z,Yang X,Sun D,Song J,Chen G,Juba O,Yang Q

更新日期：2010-12-01 00:00:00

abstract：:Ribosomal protein S3 (RPS3) is a component of the 40S ribosomal subunit. It is known to function in ribosome biogenesis and as an endonuclease. RPS3 has been shown to be over expressed in colon adenocarcinoma but its role in colon cancer is still unknown. In this study, we aim at determining the expression levels of R...

journal_title：Molecular biology reports

authors： Alam E,Maaliki L,Nasr Z

更新日期：2020-08-01 00:00:00

abstract：:Cerebral aneurysm affects 2-5% of the population and posterior inferior cerebellar artery (PICA) aneurysms account for 1-3% of all intracranial aneurysms. Oxidative stress is known to contribute to the progression of cerebrovascular disease and it may be increased by inflammation, a key contributor to cerebral aneurys...

journal_title：Molecular biology reports

authors： Šćepanović V,Tasić G,Repac N,Nikolić I,Janićijević A,Todorović D,Stojanović M,Šćepanović R,Mitrović D,Šćepanović T,Borozan S,Šćepanović L

更新日期：2018-12-01 00:00:00

abstract：:The aim of this study was to determine whether tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) promoter polymorphisms confer susceptibility to periodontitis in ethnically different populations. A literature search was performed using PubMed and Embase and a meta-analysis of the identified studies was conducte...

journal_title：Molecular biology reports

authors： Song GG,Choi SJ,Ji JD,Lee YH

更新日期：2013-08-01 00:00:00

abstract：:Male Breast Cancer (MBC) is a rare and aggressive disease that is associated with genetic factors. Mutations in BRCA1 and BRCA2 account for 10% of all MBC cases suggesting that other genetic factors are involved. The aim of the present study is to screen whole BRCA1 and BRCA2 exons using the Ampliseq BRCA panel in Tun...

journal_title：Molecular biology reports

authors： Ben Kridis-Rejeb W,Ben Ayed-Guerfali D,Ammous-Boukhris N,Ayadi W,Kifagi C,Charfi S,Saguem I,Sellami-Boudawara T,Daoud J,Khanfir A,Mokdad-Gargouri R

更新日期：2020-09-01 00:00:00

abstract：:An ORF having a potential to code for a polypeptide of 79 amino acids has been identified within 993 nt sequence of 2 kb EcoRI-W fragment of Spodoptera litura nucleopolyhedrovirus (SpltNPV-I). Nucleotide and deduced amino acid sequence analyses showed its identity with the ubiquitin homologue of eukaryotes (79-80%), M...

journal_title：Molecular biology reports

authors： Jain M,Das RH

更新日期：2004-12-01 00:00:00

abstract：:Although there are many studies on the role of PI3K/AKT/mTOR pathway and autophagy genes in the mechanism of head and neck cancer formation and prognostic significance, there is no study investigating the role of the genes in paranasal sinus carcinomas. The aim of the study was to assess the role of the PI3K/AKT/mTOR ...

journal_title：Molecular biology reports

authors： Biray Avci C,Sezgin B,Goker Bagca B,Karci HB,Gode S

更新日期：2020-05-01 00:00:00

abstract：:Stats are latent transcription factors involved in normal cellular signaling in response to cytokine or growth factor stimulation. Constitutive activation of Stats (primarily Stat3 and Stat5) has been implicated in growth dysregulation and oncogenesis. Furthermore, increased activation of Stats has been observed in se...

journal_title：Molecular biology reports

authors： Barboza JA,Wang S,Schaefer TS

更新日期：2004-03-01 00:00:00

abstract：:CyclinD1 over-expression is the key pathogenetic event underlying airway smooth muscle (ASM) proliferation. Human antigen R (HuR) is a ubiquitously expressed RNA-binding protein, and is known to regulate the expression of multiple cell cycle regulators. The aim of the study is to investigate whether HuR might also be ...

journal_title：Molecular biology reports

authors： Zhang P,Cao M,Liu Y,Lv Z,Yang Q,Lin X,Li H,Wan Q

更新日期：2012-05-01 00:00:00

abstract：:Overexpression of domains of a human protein using recombinant DNA technology has been challenging because individual domains intend to accumulate as non-soluble aggregate when expressed separately. Studies on identifying right sequences for a domain to be able to fold independently may help understand the folding pat...

journal_title：Molecular biology reports

authors： Tiwary M,Agarwal N,Dinda A,Yadav SC

更新日期：2016-05-01 00:00:00

abstract：:Altered expression and methylation pattern of tumor suppressor and DNA repair genes, in particular involved in mismatch repair (MMR) pathway, frequently occur in primary colorectal (CRC) tumors. However, little is known about (epi)genetic changes of these genes in precancerous and early stages of CRC. The aim of this ...

journal_title：Molecular biology reports

authors： Polakova Vymetalkova V,Vannucci L,Korenkova V,Prochazka P,Slyskova J,Vodickova L,Rusnakova V,Bielik L,Burocziova M,Rossmann P,Vodicka P

更新日期：2013-10-01 00:00:00

abstract：:The peroxisome proliferator-activated receptor-γ (PPARG) is a member of the nuclear hormone receptor superfamily that has attracted considerable attention as a candidate gene for coronary heart disease (CHD) based on its function as a key factor involved in the regulation of lipid and glucose metabolism. In the past d...

journal_title：Molecular biology reports

authors： Xu W,Xu J,Sun B,Chen H,Wang Y,Huang F,Xi P,Jiang J

更新日期：2013-02-01 00:00:00

abstract：:A reduction in the number of functional β-cells is the central pathological event in diabetes. Liver and ventral pancreas differentiates simultaneously in the same general domain of cells within embryonic endoderm. In addition, the precursor cell population being bi-potential may be targeted for either pancreas or liv...

journal_title：Molecular biology reports

authors： Sarkar S,Munshi C,Chatterjee S,Mukherjee S,Bhattacharya S

更新日期：2019-10-01 00:00:00

abstract：:The interaction between ovalbumin (OVA) and three purine alkaloids (caffeine, theophylline and diprophylline) was investigated by the aid of intrinsic and synchronous fluorescence, ultraviolet-vis absorbance, resonance light-scattering spectra and three-dimensional fluorescence spectra techniques. Results showed that ...

journal_title：Molecular biology reports

authors： Wang RQ,Yin YJ,Li H,Wang Y,Pu JJ,Wang R,Dou HJ,Song CJ,Wang RY

更新日期：2013-04-01 00:00:00