Abstract:
BACKGROUND:Assessment of impaired motor behaviour serves as tool for diagnosis and for evaluation of progression of chronic neurodegeneration. METHODS:We measured performance of rapid alternating movements, simple and complex motion series with instruments in scored, drug naïve patients with Huntington's disease and controls. OBJECTIVES:To compare device outcomes with the ones of controls and to correlate them with each other and with the disease symptoms. RESULTS:Patients showed lower peak velocities and longer intervals for performance of rapid alternating movements than the controls. On the right dominant side, a correlation was found between intervals needed for standardised alternating movement performance and the simple motion task outcomes in the patients. No relations to the rated disease symptoms appeared. CONCLUSION:Execution of alternating movements is disturbed in Huntington's disease. Performance of the simple motion task and realisation of alternating motions shares a need for low cognitive efforts. Both ask for a more automated motion execution. Therefore they were related to each other to a certain extent. Execution of complex movement series asks for higher cognitive load, as it demands aiming and planning of movement series with visual input. This motion pattern does not resemble to the realisation of rapid alternating movements.
journal_name
NeuroRehabilitationjournal_title
NeuroRehabilitationauthors
Müller T,Saft C,Andrich J,Harati Adoi
10.3233/NRE-130992subject
Has Abstractpub_date
2013-01-01 00:00:00pages
649-55issue
4eissn
1053-8135issn
1878-6448pii
V13446H370912126journal_volume
33pub_type
杂志文章abstract:BACKGROUND:Segmental muscle vibration (SMV) improves motor performances in neurological conditions, including stroke. OBJECTIVE:To determine if SMV modifies upper limb muscular activity in chronic stroke patients performing a reaching movement. METHODS:We randomized 22 chronic stroke patients to an experimental group...
journal_title:NeuroRehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.3233/NRE-141131
更新日期:2014-01-01 00:00:00
abstract:INTRODUCTION:While cognitive impairment is a recognised feature of Parkinson's disease (PD), few studies have evaluated the validity of brief cognitive screening measures compared to a comprehensive neuropsychological assessment. This studies aim was to evaluate the sensitivity and specificity of the Mini-Mental State ...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-182433
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Attention deficits are common after acquired brain injury (ABI) and adversely impact academic, vocational and social outcomes. The role of cognitive interventions in post-ABI attention rehabilitation remains unclear. OBJECTIVE:To evaluate effectiveness of cognitive interventions in treating attention defici...
journal_title:NeuroRehabilitation
pub_type: 杂志文章,meta分析,评审
doi:10.3233/NRE-151225
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Robotic guidance has been shown to facilitate motor skill acquisition, through altered sensorimotor control, in neurologically impaired and healthy populations. OBJECTIVE:To determine if robot-guided practice and online visual feedback availability primarily influences movement planning or online control me...
journal_title:NeuroRehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.3233/NRE-141168
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:To explore unprompted adherence to a personalized, home-based, computerized cognitive training program in patients with multiple sclerosis (MS), and to examine the impact of training on cognitive performance. METHODS:Participants were assigned to a training (n=59) or a control group (n=48). Those in the tra...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-2010-0546
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVES:To present a framework for the diagnosis and treatment of inner ear disorders, with an emphasis on problems common to neuro-rehabilitation. INTRODUCTION:Disorders of the inner ear can cause hearing loss, tinnitus, vertigo and imbalance. Hearing loss can be conductive, sensorineural, or mixed; conductive hea...
journal_title:NeuroRehabilitation
pub_type: 杂志文章,评审
doi:10.3233/NRE-130868
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVES:Prism Adaptation (PA) is a technique used in the rehabilitation of unilateral spatial neglect. Several researchers have reported positive results on a number of tasks, but negative outcomes have also been reported. These conflicting results could be due to the use of prisms of different power. The aim of thi...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-130908
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Systemic inflammation and its impact on rehabilitation for patients with non-traumatic haemorrhagic injury (HBI) sequelae has not yet been adequately documented. OBJECTIVE AND METHODS:We therefore considered 31 patients with HBI, to determine the serum levels of inflammatory markers (C-Reactive Protein, CRP...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-182362
更新日期:2018-04-07 00:00:00
abstract:BACKGROUND:Endocrinopathy, including hypogonadism, is common following traumatic brain injury (TBI). Prior evidence suggests hypogonadism is associated with poorer function. OBJECTIVE:Determine the feasibility, safety, and efficacy of testosterone (T) therapy in hypogonadal men following TBI in acute rehabilitation. ...
journal_title:NeuroRehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.3233/NRE-192992
更新日期:2020-01-01 00:00:00
abstract::The management of pain in persons with neurological injuries is challenging and complex. A holistic view and clinical approach are necessary when addressing pain in patients with neurological impairment because interpreting signs and symptoms and deciphering sources of pain is never a straightforward process. This pro...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-208003
更新日期:2020-01-01 00:00:00
abstract::Individuals with acquired brain injuries often display problematic behaviors, such as impulsivity, disinhibition, lack of initiation, isolation, and aggression, that impact their readiness to return to home and/or the community. The occurrence and treatment of these behaviors is often complicated by impairments in cog...
journal_title:NeuroRehabilitation
pub_type: 杂志文章,评审
doi:10.3233/NRE-2012-0773
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:There is psychometric evidence that supports the six-minute walk (6MW) as a measure of walking performance, whereas other psychometric data support it as a submaximal measure of physical fitness in persons with MS. OBJECTIVE:The current cross-sectional study compared measures of walking performance and phys...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-151247
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:Although deemed a globally accepted framework, there remains scare evidence on the process and outcome of implementing the International Classification of Functioning, Disability and Health (ICF) within neurorehabilitation. OBJECTIVES:This review briefly explores the existing, broader literature and then ...
journal_title:NeuroRehabilitation
pub_type: 杂志文章,评审
doi:10.3233/NRE-141185
更新日期:2015-01-01 00:00:00
abstract::The ability of the adult central nervous system to recover from injury is highly limited. Limiting factors in the repair process appear to be a combination of an inhibiting environment and the restricted intrinsic capacity of the neuron to reactivate its regenerative machinery. Studies using experimental treatments de...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-1998-10204
更新日期:1998-01-01 00:00:00
abstract::We investigated the long-term effects of comprehensive hand repetitive intensive strengthening training (CHRIST) on strength, morphological muscle size, kinematics, and associated motor functional changes in children with cerebral palsy (CP). Ten children (5 boys, 5 girls; age range, 6-11 years, mean age, 8.6 years) p...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-130846
更新日期:2013-01-01 00:00:00
abstract::Proper management of elbow spasticity is important in stroke rehabilitation. We investigated the effect and safety of ultrasound guided alcohol neurolysis of the MC nerve for controlling elbow flexor spasticity in hemiparetic stroke patients. Ten hemiparetic stroke patients with severe elbow spasticity were recruited ...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-2012-00806
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:The restoration of trunk function following stroke is a key component of rehabilitation, however there is limited evidence of the efficacy of additional trunk training. OBJECTIVES:To evaluate the efficacy of trunk exercises added to conventional rehabilitation on functional outcomes. METHODS:Relevant rando...
journal_title:NeuroRehabilitation
pub_type: 杂志文章,meta分析,评审
doi:10.3233/NRE-141123
更新日期:2014-01-01 00:00:00
abstract:INTRODUCTION:Dysphagia is a frequent problem in various neurological disorders. However, knowledge on swallowing function in patients with cerebral hypoxia is sparse. The objective of this study is to report the development of swallowing function in a series of adolescent and young-adult patients with cerebral hypoxia....
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-182437
更新日期:2018-01-01 00:00:00
abstract::Long-term outcome assessment of people with spinal cord injury (SCI) beyond acute rehabilitation is becoming an increasingly important issue as life expectancies for people with SCI approach those of the general population. This article provides information about research on the long-term physical and psychological we...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-1995-5106
更新日期:1995-01-01 00:00:00
abstract::Many patients with post-poliomyelitis syndrome can benefit from a management program. When a post-polio patient presents with new symptoms, it is first essential to identify and treat other medical and neurological conditions which could produce these symptoms. New weakness can be managed with exercise (stretching, st...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-1997-8204
更新日期:1997-01-01 00:00:00
abstract:UNLABELLED:We recently developed a computer-based test that uses a pointing task with multiple levels of difficulty to evaluate upper extremity motor function. The purpose of this study is to report performance data in adults and children, to determine test reliability, and to validate this test against well establishe...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-2012-00816
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Traumatic brain injury (TBI) remains a silent and global epidemic which creates an aftermath of convoluted dynamics. Despite significant incidence rates and increasing awareness over the long-term catastrophic implications, there remain marked contrasts between acute vs. post-acute rehabilitation processes i...
journal_title:NeuroRehabilitation
pub_type: 杂志文章,评审
doi:10.3233/NRE-192969
更新日期:2020-01-01 00:00:00
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journal_title:NeuroRehabilitation
pub_type: 杂志文章,meta分析
doi:10.3233/NRE-2012-0751
更新日期:2012-01-01 00:00:00
abstract::Respiratory symptoms are recognized as sequelae of motor dysfunction in idiopathic Parkinson's disease (IPD) and these symptoms have the potential to cause problems with swallow, cough, voice and speech. Specifically, maneuvers that require rapid activation and coordination of upper airway and chest wall musculature b...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Dystonia is the third common motor disorder; deep brain stimulation (DBS) has been reported as beneficial in selected dystonia patients. OBJECTIVE:To assess the effects of DBS in adults with dystonia. METHODS:Cochrane Review conducted by Rodrigues et al. searching for RCTs with a parallel design, comparing...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-199010
更新日期:2019-12-18 00:00:00
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journal_title:NeuroRehabilitation
pub_type: 杂志文章,评审
doi:10.3233/NRE-151215
更新日期:2015-01-01 00:00:00
abstract::Ethical issues pertaining to treating pediatric rehabilitation patients stem from at least three sources: the fact that children are not morally autonomous persons and must depend on the values and moral beliefs of others in ethically complex decision-making situations; the extent of parental authority in asserting pr...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-1993-3306
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVE:To generate normative data for the Peabody Picture Vocabulary Test-III (PPVT-III) in Spanish-speaking pediatric populations. METHOD:The sample consisted of 4,373 healthy children from nine countries in Latin America (Chile, Cuba, Ecuador, Honduras, Guatemala, Mexico, Paraguay, Peru, and Puerto Rico) and Spai...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-172239
更新日期:2017-01-01 00:00:00
abstract::Many issues face the National Institute on Disability and Rehabilitation Research (NIDRR) and its role in the encouragement of Traumatic Brain Injury (TBI) rehabilitation research and the development of the TBI model systems of care. Yet, even though many complex difficulties face individuals who have sustained TBI, t...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-1996-7306
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:Lightning-related injuries most often involve impairment of the functions of the central and peripheral nervous systems, usually including cognitive dysfunctions. We evaluated the cognitive deficit of a patient who had survived a lightning strike and measured the improvement after her cognitive training. Thi...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-141106
更新日期:2014-01-01 00:00:00