Abstract:
:We report a fatal case of streptococcal and meningococcal meningitis in a previously healthy 2-year-old child, a simultaneous co-infection of both pathogens that is poorly reported in the reviewed literature. The lack of a clinical diagnosis in addition to the medico-legal aspects arising from possible professional liability for the emergency service doctor who had failed to recognize the child's symptoms led to a forensic autopsy within 48 h after the death. After external and internal examination, Waterhouse-Friderichsen Syndrome (WFS) was suspected. Consequently, cerebrospinal fluid, whole blood, nasal and pharyngeal swab and pleural liquid samples were selected and collected for microbiological studies. All tested samples resulted Neisseria meningitidis DNA and Streptococcus pneumoniae DNA positive. The NM genotyping Real-Time PCR resulted positive for NM serotype C. Microscopic histological study confirmed these findings. We underline that when a patient presents fever and petechiae (50-60% of patients), WFS must be considered, even when the patient has a non-toxic appearance. Due to its rapid progression and often devastating consequences, therapy should be started as soon as WFS is suspected. Emphasis should also be placed on the importance of public education programs and on broadening protection against meningitis through new vaccines. In such cases, from a forensic point of view, there is a strong need for a robust, multidisciplinary approach in order to reach the correct post-mortem diagnosis.
journal_name
J Forensic Leg Medjournal_title
Journal of forensic and legal medicineauthors
Ventura F,Bonsignore A,Portunato F,Orcioni GF,Varnier OE,De Stefano Fdoi
10.1016/j.jflm.2013.04.004subject
Has Abstractpub_date
2013-08-01 00:00:00pages
678-82issue
6eissn
1752-928Xissn
1878-7487pii
S1752-928X(13)00116-9journal_volume
20pub_type
杂志文章abstract::Adherence to local guidelines on the use of HIV post exposure prophylaxis (PEP) and hepatitis B vaccine following sexual assault was evaluated by means of audit. Forensic Medical Examiners (FMEs) were asked to complete an audit form after conducting sexual offence examinations at Gloucester Sexual Assault Referral Cen...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2011.07.009
更新日期:2011-11-01 00:00:00
abstract::As forensic DNA technology has become a common tool in criminal investigations, scientists have attempted to obtain DNA evidence from what were once considered unlikely sources. "Touch DNA" refers to the DNA that is left behind from skin cells when a person touches or comes into contact with an item. This present stud...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2011.05.007
更新日期:2011-10-01 00:00:00
abstract::Recent publications argue that classic metaphyseal fractures are caused by rickets as opposed to trauma. Previous case reports of accidental traumatic classic metaphyseal fractures have been discounted due to lack of identification of the fracture at the time of the traumatic event, and lack of an evaluation for boney...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2015.07.005
更新日期:2015-10-01 00:00:00
abstract::The purpose of this study was to record and evaluate the causes and the magnitude of the fatal burn injuries retrospectively. An analysis of autopsy records revealed 19.4% cases of burn injuries amongst the total autopsies done over 10years period (1993-2002) in the mortuary of the department of Forensic Medicine of K...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jcfm.2005.09.002
更新日期:2007-01-01 00:00:00
abstract::Isolated populations present a constant threat to the correctness of forensic genetic casework. In this review article we present several examples of how analyzing samples from isolated populations can bias the results of the forensic statistics and analyses. We select our examples from isolated populations from centr...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章,评审
doi:10.1016/j.jflm.2017.04.001
更新日期:2017-05-01 00:00:00
abstract::An investigation was performed with the aim of assessing the success rate of the examination of penile swabs or imprints for the detection of the female DNA profile. Two hundred twenty seven cases from a 3-year period were retrospectively reviewed. In 57% of the cases, no suitable material was available. Of the remain...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jcfm.2006.05.003
更新日期:2007-04-01 00:00:00
abstract::Identification of the dead is significant in examination of unknown, decomposed and mutilated human remains. Establishing the biological profile is the central issue in such a scenario, and stature estimation remains one of the important criteria in this regard. The present study was undertaken to estimate stature fro...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2018.04.004
更新日期:2018-08-01 00:00:00
abstract::Insects are an important group involved in carrion consumption and are thus of forensic interest. In the laboratory we studied the taphonomic marks that Necrobia rufipes (Cleridae) can produce. Pig trotters were exposed to adult beetles at 21 ± 3 °C and 12:12 h day/night cycle. We made observations and took photograph...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2015.04.020
更新日期:2015-07-01 00:00:00
abstract::Foot impressions are of utmost importance in crime scene investigations. Foot impressions are available in the form of barefoot prints, sock-clad footprints, and as impressions within footwear. Sometimes suspects leave their footwear at the crime scene, and the insole of this footwear may contain the foot impression o...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2017.09.005
更新日期:2017-11-01 00:00:00
abstract::This study uses statistical techniques to evaluate reports on suicide scenes; it utilizes 80 reports from different locations in Brazil, randomly collected from both federal and state jurisdictions. We aimed to assess a heterogeneous group of cases in order to obtain an overall perspective of the problem. We evaluated...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2014.06.004
更新日期:2014-08-01 00:00:00
abstract::The presence of semen is generally accepted as evidence in sexual assault cases prosecution. Detection of sperm is confirmation of semen; however, sperm cannot always be detected. Prostate specific antigen (PSA) and semenogelin (Sg) are used as semen biomarkers. We compared the detection rate and persistence of sperm,...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2017.12.017
更新日期:2018-02-01 00:00:00
abstract::We reviewed the medical records of the 118 adolescent detainees which had at least one consultation by a psychiatrist at the prison health facility during 2007. General practitioners used the International Classification of Primary Care (ICPC-2) for recording health problems. Psychiatrists used the International Class...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2012.02.013
更新日期:2012-08-01 00:00:00
abstract:AIMS:To evaluate premature mortality and causes of death from young adulthood to middle age in a cohort of drug users followed during almost four decades. DESIGN:Follow-up study of a consecutive cohort of patients with drug abuse/dependence. METHODS:A cohort of 561 drug abusers, admitted to a detoxification and short...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2011.01.003
更新日期:2011-02-01 00:00:00
abstract::The presence of insects on human cadavers has potential judicial value in medicolegal cases. This research emphasized the important role of insects in postmortem decomposition. It was conducted to investigate the composition and abundance of insects from human corpses during autopsies in legal medicine. It was impleme...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2017.12.016
更新日期:2018-02-01 00:00:00
abstract::An elderly man was stabbed with a needle and syringe onto his abdomen while asleep. He progressively developed respiratory failure and coma and died an hour later. Autopsy findings and laboratory analysis confirmed the death as being due to poisoning by cyanide. This case highlights the need to consider cyanide as a p...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2011.02.010
更新日期:2011-05-01 00:00:00
abstract::Necrophilia is a paraphilia whereby the perpetrator gets sexual pleasure in having sex with the dead. Most jurisdictions and nations have laws against this practice. Necrophilia exists in many variations, and some authors have attempted to classify necrophilia. However many related terms such as pseudonecrophilia cont...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2008.12.023
更新日期:2009-08-01 00:00:00
abstract::The aim of this research was to generate a standard formula for estimating stature in the Bangladeshi population from hand anthropometric measurements. Arbitrarily selected a total of 150 male and 150 female healthy subjects within the age range 18-60 years participated in this study. Stature and nine hand parameters ...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2019.05.006
更新日期:2019-07-01 00:00:00
abstract::Paternity disputes and other forms of kinship testing are routinely resolved using short tandem repeat (STR) DNA loci. Sibship determination is encountered in instances where the DNA profiles of two individuals are compared to determine if they are siblings. If either parent is available for testing then the situation...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2007.12.018
更新日期:2008-07-01 00:00:00
abstract::The purpose of this study was to identify the extent and types of drugs found in alleged drug facilitated sexual assaults (DFSA) in 37 states and 1 territory of the United States. In total, 1000 cases were reviewed. Between the cases that gender was provided (613), most of the victims (91.68%) were woman, mean age of ...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2018.11.006
更新日期:2019-02-01 00:00:00
abstract::My experience of the new Diploma in the Forensic and Clinical aspects of Sexual Assault and how this could be used as guidance for future candidates. ...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2011.09.007
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:In recent years, suicide in children and adolescents has increased considerably, becoming the second cause of death in this age group. Therefore, the aim of this study was to identify characteristics and factors that could precipitate deaths by suicide in children and adolescents. METHODS:Using the psycholog...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2017.10.002
更新日期:2017-11-01 00:00:00
abstract::A 19 year old male was admitted to a tertiary care centre in Sri Lanka, with a history of snake bite while sleeping at night. A killed specimen of a snake was brought with the patient. It had been identified as a non-venomous snake by the doctor and handed over to relatives, with a comment to that effect. Patient had ...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2013.09.009
更新日期:2013-11-01 00:00:00
abstract::Not only does the Bayesian approach offer a rational and logical environment for evidence evaluation in a forensic framework, but it also allows scientists to coherently deal with uncertainty related to a collection of multiple items of evidence, due to its flexible nature. Such flexibility might come at the expense o...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2018.02.005
更新日期:2018-04-01 00:00:00
abstract::The study of cause-specific mortality data is one of the main sources of information for public health monitoring. In most industrialized countries, when a death occurs, it is a legal requirement that a medical certificate based on the international form recommended by World Health Organization's (WHO) is filled in by...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2016.12.004
更新日期:2018-07-01 00:00:00
abstract:INTRODUCTION:Cutaneous bruises are often hard to detect particularly on individuals with a darker complexion. Researchers and federal agencies have recommended the use of alternate light to aide in the assessment of subtle injury. However, studies are limited in their evaluation of wavelength performance during the fir...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2019.101893
更新日期:2020-01-01 00:00:00
abstract::Estimation of time of death (TOD) with fair accuracy from postmortem changes still remains an important but difficult task to be performed by every autopsy surgeon under different climatic conditions. The environment plays an important role in the process of decomposition and thereby affecting the levels of electrolyt...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2014.09.004
更新日期:2014-11-01 00:00:00
abstract::The case of a missing person is described whose body was discovered almost 8 months later on a secluded beach on the Solway coast, south west Scotland. The delay in discovery was due to the foot and mouth outbreak in the UK in 2001 and this resulted in conditions favouring the development of partial mummification. The...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jcfm.2006.01.006
更新日期:2007-01-01 00:00:00
abstract::Documentation of torture is a multidisciplinary, multistage scientific procedure evolved over the past decades through the experience of various strata in medical and related fields. It plays a key role in effective corroboration of facts, providing redress to victims and also has a long term regulatory impact on prev...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章,评审
doi:10.1016/j.jflm.2010.09.010
更新日期:2011-01-01 00:00:00
abstract::A 7-year old girl suspected of having been sexually abused owing to the presence of anal condyloma was found to be infected by Chlamydia trachomatis. Microbiological analysis and anamnesis were consistent with the infection having been acquired at birth. This case confirms that untreated infection acquired at birth ca...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2009.07.018
更新日期:2010-02-01 00:00:00
abstract:UNLABELLED:Falanga torture involves repetitive blunt trauma to the soles of the feet and typically leaves few detectable changes. Reduced elasticity in the heel pads has been reported as characteristic sequelae and palpatory testing of heel pad elasticity is therefore part of medicolegal assessment of alleged torture v...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2008.03.003
更新日期:2008-10-01 00:00:00