Abstract：
:Paternity disputes and other forms of kinship testing are routinely resolved using short tandem repeat (STR) DNA loci. Sibship determination is encountered in instances where the DNA profiles of two individuals are compared to determine if they are siblings. If either parent is available for testing then the situation is simplified but if neither parent of the two individuals is available for DNA testing, a combined sibling indices (CSI) for the determination of sibship between two people can be determined. Support for kinship is also based upon the sharing of alleles, particularly when both alleles are shared at the same locus, termed two-allele-sharing-loci (TASL). We report on the combination of CSI and TASL to enhance the determination of sibship. The 15 STR loci that comprise the Identifiler loci were applied to three populations using pairs of full siblings or unrelated pairs. Based upon the data obtained, the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) can be applied to determining whether two DNA profiles come from full or non-sibling pairs. This report highlights the problems inherent in this form of kinship testing and recommends a combination use of CSI and TASL for sibship determination.
journal_name
J Forensic Leg Medjournal_title
Journal of forensic and legal medicineauthors
Pu CE,Linacre Adoi
10.1016/j.jflm.2007.12.018subject
Has Abstractpub_date
2008-07-01 00:00:00pages
329-34issue
5eissn
1752-928Xissn
1878-7487pii
S1752-928X(08)00008-5journal_volume
15pub_type
杂志文章abstract：:To explore the CT characteristics of orbital blowout fracture, we reviewed 76 cases with orbital blowout fracture and analyzed their clinical forensic characteristics. The missed diagnosis rate of cranial CT was 26.3%, and plain X-ray was 47.4%. The orbital CT examination has advantages in diagnosing orbital blowout f...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2007.12.010
更新日期：2009-01-01 00:00:00
abstract：:Ethanol determination in postmortem blood is one of the most frequently requested analyses in legal medicine and forensic toxicology. Ethyl glucuronide is a non-oxidative ethanol metabolite. It is also a useful marker of ante-mortem alcohol ingestion when ethanol itself has been completely eliminated from the body and...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2017.10.009
更新日期：2018-01-01 00:00:00
abstract：AIMS:To report on a health needs assessment undertaken in the Durham Constabulary (England) in 2013. METHODOLOGY:The health needs assessment employed a variety of methods: analysis of arrest and healthcare data over a one year period; semi-structured interviews with the police and healthcare staff; and a survey of det...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2015.11.013
更新日期：2018-07-01 00:00:00
abstract：:Intimate partner violence (IPV) is a significant worldwide problem whose magnitude and risk factors vary across different settings and cultures. Nowadays, it is a priority to improve the knowledge on this issue in order to formulate better evidence-based policy responses. This study aims to contribute to a better unde...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2015.05.012
更新日期：2015-08-01 00:00:00
abstract：:The presence of vaginal fluid as a bio-stain in the crime scene of sexual assaults provides pivotal evidence. The vaginal secretions are known to be rich in Lactobacillus; hence the current work aims to identify vaginal secretions via detection and quantification of Lactobacillus DNA in pre and postmenopausal females ...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2019.06.004
更新日期：2019-08-01 00:00:00
abstract：:In medico-legal autopsies, establishing personal identity of the victims is often required. Estimation of stature from extremities and their parts plays an important role in identifying the dead in forensic examinations. The study examines the relationship between stature and dimensions of hands and feet among Rajputs...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jcfm.2006.10.008
更新日期：2007-08-01 00:00:00
abstract：:The antidepressant milnacipran is a double serotonin/noradrenalin reuptake inhibitor. The low reported incidence of intoxication indicates excellent tolerance in comparison with tricyclic and second generation antidepressants. We report a fatal intoxication associating milnacipran, at blood levels (femoral=21.5 mg/l, ...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2007.12.006
更新日期：2008-08-01 00:00:00
abstract：:The aim of this study was to assess whether Neisseria meningitidis, Listeria monocytogenes, Streptococcus pneumoniae and Haemophilus influenzae can be identified using the polymerase chain reaction technique in the cerebrospinal fluid of severely decomposed bodies with known, noninfectious causes of death or whether p...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2014.12.012
更新日期：2015-02-01 00:00:00
abstract：:Ballistic trauma caused by bullets can be fatal or cause serious injury. Despite the abundance in literature in management of bullet injuries, there is paucity in describing how the operating surgeon should handle the bullet intra operatively. Bullets are important pieces of evidence and evidence preservation becomes ...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2017.03.003
更新日期：2017-05-01 00:00:00
abstract：UNLABELLED:Falanga torture involves repetitive blunt trauma to the soles of the feet and typically leaves few detectable changes. Reduced elasticity in the heel pads has been reported as characteristic sequelae and palpatory testing of heel pad elasticity is therefore part of medicolegal assessment of alleged torture v...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2008.03.003
更新日期：2008-10-01 00:00:00
abstract：AIM:Infantile cerebral palsy (CP) severely affects the survival and quality of life of infants. CP is typically caused by multiple factors, leading to causal uncertainty of the role of medical errors in CP and resulting in frequent medical disputes. No relevant research exists on risk management and malpractice liabili...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2018.11.010
更新日期：2019-02-01 00:00:00
abstract：:Forensic pathologists can help in the investigation of sudden unexpected deaths in co-operation with the officials responsible for the maintenance of law and order to administer justice. Sudden unexpected deaths form the subject of medicolegal investigation if they occur in apparently healthy individuals, wherein an a...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2010.04.013
更新日期：2010-08-01 00:00:00
abstract：INTRODUCTION:Statistics on death are the basis of a country's health, safety, and welfare policies. Emergency physicians issue a postmortem examination certificate (PEC) for death outside the hospital as well as a death certificate (DC) for death in the hospital. This study investigated the actual conditions and criter...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2020.101960
更新日期：2020-05-01 00:00:00
abstract：:Mitochondrial DNA analysis is very useful for the interpretation of the history of human migration and to estimate the frequency of a haplotype in the forensic context. From a human settlement perspective, La Paz area is greatly interesting since the first planned city of the region is located there. Samples from 110 ...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2010.02.011
更新日期：2010-07-01 00:00:00
abstract：:As forensic DNA technology has become a common tool in criminal investigations, scientists have attempted to obtain DNA evidence from what were once considered unlikely sources. "Touch DNA" refers to the DNA that is left behind from skin cells when a person touches or comes into contact with an item. This present stud...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2011.05.007
更新日期：2011-10-01 00:00:00
abstract：:To characterize discrepancies between the causes of death as determined by the clinician and autopsy findings in patients admitted with stroke, we retrospectively reviewed all autopsies on patients died with a diagnosis of stroke. Fifty-eight patients with a diagnosis of stroke died after admission to our tertiary med...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2013.09.020
更新日期：2013-11-01 00:00:00
abstract：:A 5-year-old boy with a chromosome-9 abnormality and multiple external and visceral malformations was found in cardiopulmonary arrest during a regular visit to the hospital; he did not respond to cardiopulmonary resuscitation and died. An odontoid process fracture and calcification and fibrosis of the muscles around t...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2018.11.011
更新日期：2019-02-01 00:00:00
abstract：INTRODUCTION:Effectiveness and safety assessment for kinetic energy (KE) bullets is of importance, considering numerous reports about excessive damage cases of KE bullets in recent years. Early study of KE impacting targets mainly focused on threshold penetration issue, but did not involve cavity evolution of target an...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2019.07.009
更新日期：2019-10-01 00:00:00
abstract：:Kissed (1996) is a serious film that portrays the disturbing and taboo issue of necrophilia in a delicate and viewer friendly way. Being a rare paraphilia, it may sometimes be difficult to get necrophilia related literature or even understand this complex behavior. An interested person may have to rely on the few case...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2012.06.001
更新日期：2013-04-01 00:00:00
abstract：:The aim of the study was to assess interdoctorvariation and validity in death certification by forensic physicians using 19 written scenarios. The scenarios described typical cases from forensic-medical practice. Physicians were asked to determine the manner of death (natural/unnatural) and to provide an ICD-10 code f...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2016.07.005
更新日期：2016-10-01 00:00:00
abstract：:This study analysed the daily incidence of sexual assault in Greater Manchester with respect to the local weather conditions throughout the year 2002. Cases seen at the St. Mary's Sexual Assault Referral Centre (including police and self-referred clients) for which the date of the assault was known were included in th...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jcfm.2005.12.001
更新日期：2007-01-01 00:00:00
abstract：:An investigation was performed with the aim of assessing the success rate of the examination of penile swabs or imprints for the detection of the female DNA profile. Two hundred twenty seven cases from a 3-year period were retrospectively reviewed. In 57% of the cases, no suitable material was available. Of the remain...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jcfm.2006.05.003
更新日期：2007-04-01 00:00:00
abstract：:Deaths that occur in prisons riots can be by extreme violence. When unrecognizable corpses are referred for examination, the process of human identification is hampered. The aim of this study is to present applicability in human identification by ear individual signs in an inmate beheaded in Brazil prison riot. Ten pr...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2019.101870
更新日期：2019-11-01 00:00:00
abstract：:Suicide is an important health hazard worldwide. Hanging is one of the preferred means of committing suicide in India. The current research is aimed to describe the victimologic profile and find the gender differences in suicidal hanging in Manipal, South India. A 10-year retrospective review of medicolegal autopsy re...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2008.05.004
更新日期：2008-11-01 00:00:00
abstract：:Although Marfan syndrome has a range of characteristic morphological features involving the ocular, cardiovascular and musculoskeletal systems, the phenotype is variable. In addition, mutations have been identified in the gene encoding for fibrillin-1 and also in the transforming growth factor-beta receptor 2 (TGF-bet...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2007.07.010
更新日期：2008-05-01 00:00:00
abstract：INTRODUCTION:Inconsistencies abound in the current forensic literature regarding the definition, and as a result, the significance of female genital injury after sexual intercourse. These definitions are based on variables related to the anatomic locations that are examined, the actual physical findings types, and the ...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2013.04.012
更新日期：2013-08-01 00:00:00
abstract：:Firecracker display is used worldwide for celebrating religious festivities, New Year celebrations and various other occasions. Explosion during the manufacture of firecrackers can result in serious injuries. We, herein, report a case, where a person succumbed to injuries sustained in an explosion in a firecracker fac...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2009.12.002
更新日期：2010-04-01 00:00:00
abstract：:Estimation of time of death (TOD) with fair accuracy from postmortem changes still remains an important but difficult task to be performed by every autopsy surgeon under different climatic conditions. The environment plays an important role in the process of decomposition and thereby affecting the levels of electrolyt...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2014.09.004
更新日期：2014-11-01 00:00:00
abstract：:Colchicum autumnale is commonly known as autumn crocus, and as 'gowri gedde' in the southern region of Karnataka State in South India. It contains an alkaloid called colchicine, which blocks the cell division by inhibiting mitosis. We present a sporadic case of suicidal plant poisoning wherein a 24-year-old man consum...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章
doi：10.1016/j.jflm.2011.04.008
更新日期：2011-08-01 00:00:00
abstract：:Isolated populations present a constant threat to the correctness of forensic genetic casework. In this review article we present several examples of how analyzing samples from isolated populations can bias the results of the forensic statistics and analyses. We select our examples from isolated populations from centr...
journal_title：Journal of forensic and legal medicine
pub_type： 杂志文章,评审
doi：10.1016/j.jflm.2017.04.001
更新日期：2017-05-01 00:00:00
