Abstract:
:The antidepressant milnacipran is a double serotonin/noradrenalin reuptake inhibitor. The low reported incidence of intoxication indicates excellent tolerance in comparison with tricyclic and second generation antidepressants. We report a fatal intoxication associating milnacipran, at blood levels (femoral=21.5 mg/l, cardiac=20 mg/l) 40-fold higher than the usual treatment concentration, and six other molecules (fluoxetine, norfluoxetine, sertraline, cyamemazine, nordazepam and oxazepam) at therapeutic levels. To the best of our knowledge, this is the first reported fatal intoxication involving milnacipran.
journal_name
J Forensic Leg Medjournal_title
Journal of forensic and legal medicineauthors
Fanton L,Bévalot F,Grait H,Le Meur C,Gaillard Y,Malicier Ddoi
10.1016/j.jflm.2007.12.006subject
Has Abstractpub_date
2008-08-01 00:00:00pages
388-90issue
6eissn
1752-928Xissn
1878-7487pii
S1752-928X(07)00193-Xjournal_volume
15pub_type
杂志文章abstract:AIMS:To evaluate premature mortality and causes of death from young adulthood to middle age in a cohort of drug users followed during almost four decades. DESIGN:Follow-up study of a consecutive cohort of patients with drug abuse/dependence. METHODS:A cohort of 561 drug abusers, admitted to a detoxification and short...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2011.01.003
更新日期:2011-02-01 00:00:00
abstract::Injury to the male external genitalia is relatively uncommon when compared with other parts of the human body. Trauma to external genitalia could result from accidents involving motor vehicles, power farm machinery, gun shot and stab injuries. We present a rare case of traumatic degloving injury of male external genit...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2008.05.020
更新日期:2008-11-01 00:00:00
abstract::Sexual violence is defined as any sexual act forced upon a person who did not give his or her consent. Our objective is to investigate the socio-demographic features, clinical correlates, criminal behaviour characteristics, and the level of penal responsibility of sexual offenders who were referred to forensic psychia...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2015.01.003
更新日期:2015-04-01 00:00:00
abstract::These days we have fast paced traffic on our roads to help us keep up with our fast paced life. But every boon has a down side and our high velocity traffic is no exception. Here is a case report of a blunt abdominal injury following a road traffic accident. Externally the deceased had only a few grazed abrasions on t...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2013.10.007
更新日期:2014-01-01 00:00:00
abstract::Chlormequat chloride is a plant growth regulator. Chlormequat poisoning clinically resembles anticholinesterase insecticide poisoning. The cholinergic symptoms result from direct action on nicotinic and muscarinic receptors and not from inhibition of the cholinesterase activity. This case series confirms the extreme g...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2015.08.001
更新日期:2015-11-01 00:00:00
abstract::The purpose of this study was to record and evaluate the causes and the magnitude of the fatal burn injuries retrospectively. An analysis of autopsy records revealed 19.4% cases of burn injuries amongst the total autopsies done over 10years period (1993-2002) in the mortuary of the department of Forensic Medicine of K...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jcfm.2005.09.002
更新日期:2007-01-01 00:00:00
abstract::When creating a basic biological profile, determining the sex of subadult skeletal remains is always problematic and several methods for sex determination have been proposed over time. The lateral angle of the internal auditory canal has been described as a good sex predictor in adults, and here we test its reliabilit...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2011.01.008
更新日期:2011-04-01 00:00:00
abstract:INTRODUCTION:Brainstem haemorrhage is common in cases of head injury when it is associated with space-occupying lesion and increases in the intracranial pressure (duret haemorrhage), in cases of diffuse axonal injury (in dorso-lateral quadrant) and diffuses vascular injury (in the periventricular tissue). However focal...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2011.12.015
更新日期:2012-04-01 00:00:00
abstract::Isolated populations present a constant threat to the correctness of forensic genetic casework. In this review article we present several examples of how analyzing samples from isolated populations can bias the results of the forensic statistics and analyses. We select our examples from isolated populations from centr...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章,评审
doi:10.1016/j.jflm.2017.04.001
更新日期:2017-05-01 00:00:00
abstract::Measurements of hand bones length have been shown to be sexually dimorphic in many nationalities. The aim of this study is to assess the accuracy of sex determination from the length of all metacarpals and phalanges of right and left hands using X-ray radiographs and to develop a discriminant formula that can be used ...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2012.04.020
更新日期:2013-01-01 00:00:00
abstract:INTRODUCTION:Cutaneous bruises are often hard to detect particularly on individuals with a darker complexion. Researchers and federal agencies have recommended the use of alternate light to aide in the assessment of subtle injury. However, studies are limited in their evaluation of wavelength performance during the fir...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2019.101893
更新日期:2020-01-01 00:00:00
abstract::Tamponade due to rupture of the chambers of the heart, in particular the left ventricle, after blunt thoracic trauma is described only sparsely in the literature. Most cases involve multiple thoracic trauma following motor vehicle accidents. We present the case study of a five-year old victim of a household accident, ...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章,评审
doi:10.1016/j.jflm.2011.02.013
更新日期:2011-07-01 00:00:00
abstract::The skull and pelvis have been used for the estimation of sex for unknown human remains. However, in forensic cases where skeletal remains often exhibit postmortem damage and taphonomic changes the patella may be used for the estimation of sex as it is a preservationally favoured bone. The goal of the present research...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2017.12.002
更新日期:2018-02-01 00:00:00
abstract::Handprint in the scene of the crime is one of the most valuable clues in identification of the assailant. There are numerous studies on estimation of stature from direct measures of hand dimensions, but using a handprint instead, there is little research on it. So this study tried to focus on handprint as a tool used ...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2015.05.007
更新日期:2015-08-01 00:00:00
abstract::Adipocere has a long history of frightening and fascinating mankind, from so called "incorruptible saints" to the famous "iceman" and its formation on human remains has long been known and feared. Adipocere formation replaces the putrefactive changes, when the body lies buried in shallow, moist, clay, soiled grave or ...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章,评审
doi:10.1016/j.jflm.2009.07.004
更新日期:2009-11-01 00:00:00
abstract:INTRODUCTION:Statistics on death are the basis of a country's health, safety, and welfare policies. Emergency physicians issue a postmortem examination certificate (PEC) for death outside the hospital as well as a death certificate (DC) for death in the hospital. This study investigated the actual conditions and criter...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2020.101960
更新日期:2020-05-01 00:00:00
abstract::To characterize discrepancies between the causes of death as determined by the clinician and autopsy findings in patients admitted with stroke, we retrospectively reviewed all autopsies on patients died with a diagnosis of stroke. Fifty-eight patients with a diagnosis of stroke died after admission to our tertiary med...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2013.09.020
更新日期:2013-11-01 00:00:00
abstract::Legal medicine addresses the interface between medicine and law in health care. The Australian College of Legal Medicine (ACLM) established itself as the peak body in legal and forensic medicine in Australia. It helped establish the Expert Witness Institute of Australia (EWIA), the legal medicine programme at Griffith...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2007.08.003
更新日期:2008-04-01 00:00:00
abstract::All medico-legal cases investigated by the Nebraska Institute of Forensic Sciences, Inc. in Lincoln, Nebraska, USA, between 2003 and 2009, were reviewed for deaths which occurred in custody (n = 38). The causes of death, in ranked order, were natural causes 37% (14/38), followed by homicide 21% (8/38), accident 21% (8...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2012.04.008
更新日期:2012-11-01 00:00:00
abstract::Giovanni Pico della Mirandola and Angelo Poliziano were two of the most important humanists of the Italian Renaissance. They died suddenly in 1494 and their deaths have been for centuries a subject of debate. The exhumation of their remains offered the opportunity to study the cause of their death through a multidisci...
journal_title:Journal of forensic and legal medicine
pub_type: 历史文章,杂志文章
doi:10.1016/j.jflm.2018.03.016
更新日期:2018-05-01 00:00:00
abstract::Multiple self-inflicted gunshot wounds are rare and usually present a challenge to the forensic pathologist in determining the manner of death. Determining a person's capability to act following a gunshot wound can be of major importance in crime scene reconstruction and in differentiation between homicide and suicide...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2011.06.017
更新日期:2012-01-01 00:00:00
abstract::Ballistic trauma caused by bullets can be fatal or cause serious injury. Despite the abundance in literature in management of bullet injuries, there is paucity in describing how the operating surgeon should handle the bullet intra operatively. Bullets are important pieces of evidence and evidence preservation becomes ...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2017.03.003
更新日期:2017-05-01 00:00:00
abstract::Foot impressions are of utmost importance in crime scene investigations. Foot impressions are available in the form of barefoot prints, sock-clad footprints, and as impressions within footwear. Sometimes suspects leave their footwear at the crime scene, and the insole of this footwear may contain the foot impression o...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2017.09.005
更新日期:2017-11-01 00:00:00
abstract::In the present study an attempt has been made to establish standards for sex determination from the various direct and indirect measurements of the cranium. A total of 100 cranium (50 of either sex) were measured for nine direct measurements pertaining to Mastoid triangle and Opisthion-Bimastoid triangle. These measur...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2012.09.020
更新日期:2013-05-01 00:00:00
abstract::Identification of the dead is significant in examination of unknown, decomposed and mutilated human remains. Establishing the biological profile is the central issue in such a scenario, and stature estimation remains one of the important criteria in this regard. The present study was undertaken to estimate stature fro...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2018.04.004
更新日期:2018-08-01 00:00:00
abstract::Ethanol determination in postmortem blood is one of the most frequently requested analyses in legal medicine and forensic toxicology. Ethyl glucuronide is a non-oxidative ethanol metabolite. It is also a useful marker of ante-mortem alcohol ingestion when ethanol itself has been completely eliminated from the body and...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2017.10.009
更新日期:2018-01-01 00:00:00
abstract::A new strategy for sexual assault and abuse services was published by NHS England earlier this year. It called for better coordination of services along the Sexual Assault Referral Centre (SARC) pathway following a sexual assault including mental health services for children, young people and adults. Previous research...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2019.04.001
更新日期:2019-05-01 00:00:00
abstract::Estimation of time of death (TOD) with fair accuracy from postmortem changes still remains an important but difficult task to be performed by every autopsy surgeon under different climatic conditions. The environment plays an important role in the process of decomposition and thereby affecting the levels of electrolyt...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2014.09.004
更新日期:2014-11-01 00:00:00
abstract::In cases of alleged rape the complainant (or "complainer" in Scotland) may be in a position to identify the alleged assailant and as a result of the advances in forensic science the issue frequently relates to the question of consent. In addition to collection of relevant forensic samples, the forensic medical examine...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jcfm.2006.10.007
更新日期:2008-01-01 00:00:00
abstract::We report a case with an atypical entrance wound as a result of a destabilized full metal jacket bullet penetration. The destabilized bullet by an impact with the dorsal hand experiences a yawing to tumbling motion in flight. The large angle of yaw induces a larger presenting profile upon impact that contributes, asso...
journal_title:Journal of forensic and legal medicine
pub_type: 杂志文章
doi:10.1016/j.jflm.2009.01.012
更新日期:2009-10-01 00:00:00