Potential therapeutic anti-tumor effect of a Salmonella-based vaccine.

abstract：:Post licensure surveillance of adverse events following immunization (AEFI) is a fundamental activity to improve safety and maintain public confidence in vaccines.   Since 2011, the Liguria Region has been involved in the inter-regional project of post-marketing surveillance of AEFI, coordinated by the Italian Medicin...

journal_title：Human vaccines & immunotherapeutics

authors： Alicino C,Merlano C,Zappettini S,Schiaffino S,Della Luna G,Accardo C,Gasparini R,Durando P,Icardi G

更新日期：2015-01-01 00:00:00

abstract：:Cancer vaccines are designed to stimulate the body's immune system to kill tumor cells. To improve their immunogenicity, vaccine antigens must be combined with adjuvants which are able to stimulate the innate immunity and potentiate the adaptive immune response. In the last years a new generation of adjuvants mimickin...

journal_title：Human vaccines & immunotherapeutics

authors： Circelli L,Tornesello M,Buonaguro FM,Buonaguro L

更新日期：2017-08-03 00:00:00

abstract：BACKGROUND:Community acquired pneumonia (CAP) is a major cause of morbidity and mortality worldwide, and is a leading cause of hospitalization in previously healthy individuals without predisposing risk factors or comorbidities. In this study we determined PCV13 serotype distribution in adults aged ≥50 years with radio...

journal_title：Human vaccines & immunotherapeutics

authors： Regev-Yochay G,Chowers M,Chazan B,Gonzalez E,Gray S,Zhang Z,Pride M

更新日期：2018-01-01 00:00:00

abstract：:Objective: To evaluate the efficacy of an intervention utilizing patient navigators (PNs) to 1) educate families on human papillomavirus (HPV) vaccination in a clinic setting and 2) provide personalized reminders for follow-up. Method: Families with 9-17 year-old children who had no record of completing the HPV vaccin...

journal_title：Human vaccines & immunotherapeutics

authors： Berenson AB,Rupp R,Dinehart EE,Cofie LE,Kuo YF,Hirth JM

更新日期：2019-01-01 00:00:00

abstract：:Nationally, human papillomavirus (HPV) vaccination rates fall short of the Healthy People 2020 goal of 80% completion. Although strategies to increase these rates exist, low rates persist. We used concept mapping with state-level stakeholders to better understand barriers and facilitators to HPV vaccination. Concept m...

journal_title：Human vaccines & immunotherapeutics

authors： Ryan G,Avdic L,Daly E,Askelson N,Farris PE,Shannon J,McRee AL,Hanson J,Kenyon DB,Seegmiller L

更新日期：2020-12-17 00:00:00

abstract：:Various glycoprotein conjugate vaccines have been developed for the prevention of invasive meningococcal disease, having significant advantages over pure polysaccharide vaccines. One of the most important features of the conjugate vaccines is the induction of a T-cell dependent immune response, which enables both the ...

journal_title：Human vaccines & immunotherapeutics

authors： Bröker M,Berti F,Costantino P

更新日期：2016-07-02 00:00:00

abstract：:Pneumococci are capable of vaccine escape by genetic recombination at the targeted capsular locus, significantly reducing long-term vaccine effectiveness. Recently, efforts have been redirected to understanding pneumococcal biology related to potential next-generation vaccine candidates. A variety of serotype-independ...

journal_title：Human vaccines & immunotherapeutics

authors： Abry MF,Kimenyi KM,Osowo FO,Odhiambo WO,Sewe SO,Kulohoma BW

更新日期：2015-01-01 00:00:00

abstract：:The objective of this study was to calculate Vaccine Effectiveness (VE) in healthcare workers (HCW) and to compare VE between patients and HCW. A case-control investigation based on the prospective study was conducted between 2004 and 2009 in a teaching hospital. All HCW with influenza-like illness (ILI) from particip...

journal_title：Human vaccines & immunotherapeutics

authors： Vanhems P,Baghdadi Y,Roche S,Bénet T,Regis C,Lina B,Robert O,Voirin N,Ecochard R,Amour S

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Socioeconomic and health inequalities remain a huge problem in post-apartheid South Africa. Despite substantial efforts at ensuring universal access to vaccines, many children remain under-vaccinated in the country. This study aimed to assess the prevalence and factors associated with incomplete vaccination ...

journal_title：Human vaccines & immunotherapeutics

authors： Ndwandwe D,Nnaji CA,Mashunye T,Uthman OA,Wiysonge CS

更新日期：2020-07-23 00:00:00

abstract：:In 2000, China was declared polio-free. However, in 2018, wild poliovirus (WPV) was still endemic in two of its neighboring countries, making WPV importation and outbreak alarming possibilities. This study documents the seroprevalence of poliovirus antibodies before and after the polio vaccine switch in 2012 and 2017 ...

journal_title：Human vaccines & immunotherapeutics

authors： Li J,Zhang Z,Zhang H,Li M,Li X,Lu L,Huang F,Wu J

更新日期：2020-07-23 00:00:00

abstract：AIM:Pertussis continues to be a common worldwide infection in pediatric and adult populations. We aimed to study epidemiological and clinical characteristics of infants and children admitted for pertussis to a tertiary-care hospital and to investigate the risk factors for pediatric intensive care unit (PICU) admission....

journal_title：Human vaccines & immunotherapeutics

authors： Di Camillo C,Vittucci AC,Antilici L,Ciarlitto C,Linardos G,Concato C,Lancella L,Villani A

更新日期：2020-08-05 00:00:00

abstract：:We previously reported higher anti-HPV-16 and -18 immune responses induced by HPV-16/18 vaccine compared with HPV-6/11/16/18 vaccine at Month 7 (one month after completion of full vaccination series) in women aged 18-45 y in an observer-blind study NCT00423046; the differences of immune response magnitudes were mainta...

journal_title：Human vaccines & immunotherapeutics

authors： Einstein MH,Levin MJ,Chatterjee A,Chakhtoura N,Takacs P,Catteau G,Dessy FJ,Moris P,Lin L,Struyf F,Dubin G,HPV-010 Study Group.

更新日期：2014-01-01 00:00:00

abstract：:DNA vaccination holds the potential to treat or prevent nearly any immunogenic disease, including cancer. To date, these vaccines have demonstrated limited immunogenicity in vivo due to the absence of a suitable delivery system which can protect DNA from degradation and improve transfection efficiencies in vivo. Recen...

journal_title：Human vaccines & immunotherapeutics

authors： Cole G,McCaffrey J,Ali AA,McBride JW,McCrudden CM,Vincente-Perez EM,Donnelly RF,McCarthy HO

更新日期：2017-01-02 00:00:00

abstract：:Human papillomavirus (HPV) infection is a major cause of cervical cancer. HPV vaccine has been shown to be highly effective in preventing HPV infection, and understanding the genotypes of HPV infection can guide the utilization of HPV vaccine. This epidemiological study aimed to investigate the genotype distribution o...

journal_title：Human vaccines & immunotherapeutics

authors： Geng Y,Liu L

更新日期：2019-01-01 00:00:00

abstract：:Some health care providers have adopted the policy of refusing to accept into their practices families who refuse to vaccinate their children according to the standard vaccine schedule. While the frustration that drives these policies is understandable, the practice of refusing to see these families is misguided. Such...

journal_title：Human vaccines & immunotherapeutics

authors： Diekema DS

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:In China, Hib vaccine is a private-sector vaccine that is an option for parents to select to give to their children; it must be paid for out-of-pocket because it is not included in the government's Expanded Program on Immunization (EPI). We evaluated utilization patterns of Hib vaccine to provide evidence in ...

journal_title：Human vaccines & immunotherapeutics

authors： Li Y,Yue C,Wang Y,Zhu X,Martin K,Scherpbier RW,Liu J,Wang Z,Ma Y,Cheng H,Zhang Z,Wang Q,Li H,Xie S,Xiao Q,Wang H,An Z

更新日期：2018-04-03 00:00:00

abstract：:Thanks to the screening method, we estimated among target groups the 2010/2011 field vaccine effectiveness (FVE) against laboratory confirmed influenza cases seen in general practice. We also compared the values of FVE estimations obtained by using three sources of the population vaccination coverage (VC) based on thr...

journal_title：Human vaccines & immunotherapeutics

authors： Falchi A,Souty C,Grisoni ML,Mosnier A,Hanslik T,Daviaud I,Varesi L,Kerneis S,Carrat F,Blanchon T

更新日期：2013-11-01 00:00:00

abstract：:It has been theorized that Calmette-Guérin bacillus may prevent or reduce the severity of COVID-19 through a nonspecific stimulation of the immune system. A preliminary assessment of SARS-CoV-2 infection rates and outcomes among 2803 individuals affected with high risk non-muscle-invasive bladder cancer and treated wi...

journal_title：Human vaccines & immunotherapeutics

authors： Fedeli U,Porreca A,Colicchia M,Schievano E,Artibani W,Biasio LR,Palù G

更新日期：2020-09-03 00:00:00

abstract：OBJECTIVES:Economic evaluations on influenza vaccination from low resource settings are scarce and have not been evaluated using a systematic approach. Our objective was to conduct a systematic review on the value for money of influenza vaccination in low- and middle-income countries. METHODS:PubMed and EMBASE were se...

journal_title：Human vaccines & immunotherapeutics

authors： Ott JJ,Klein Breteler J,Tam JS,Hutubessy RC,Jit M,de Boer MR

更新日期：2013-07-01 00:00:00

abstract：:Three phase II randomized trials evaluated the safety/immunogenicity of two formulations of live-attenuated tetravalent dengue virus (TDEN) vaccine in dengue-endemic (Puerto Rico, Thailand) and non-endemic (US) regions (NCT00350337/NCT00370682/NCT00468858). We describe cell-mediated immune (CMI) responses; safety and ...

journal_title：Human vaccines & immunotherapeutics

authors： Moris P,Bauer KM,Currier JR,Friberg H,Eckels KH,Esquilin IO,Gibbons RV,Innis BL,Jarman RG,Simasathien S,Sun P,Thomas SJ,Watanaveeradej V

更新日期：2019-01-01 00:00:00

abstract：:Psoriasis is a chronic, immune skin disease associated with significant morbidity. Development of psoriasis is influenced by numerous genes, one allele is HLA-CW*0602. Other genes and single nucleotide polymorphisms affect immunologic pathways and antimicrobial peptide synthesis. Dendritic cells initiate psoriasis by ...

journal_title：Human vaccines & immunotherapeutics

authors： Kaffenberger BH,Lee GL,Tyler K,Chan DV,Jarjour W,Ariza ME,Williams MV,Wong HK

更新日期：2014-01-01 00:00:00

abstract：:Respiratory syncytial virus (RSV) is the most common cause of respiratory tract infections in both children and elderly people. In this study we evaluated the short- and long-term protective efficacy of a single intranasal (IN) immunization with a RSV vaccine formulation consisting of a codon-optimized fusion (F) prot...

journal_title：Human vaccines & immunotherapeutics

authors： Garg R,Latimer L,Gerdts V,Potter A,van Drunen Littel-van den Hurk S

更新日期：2017-12-02 00:00:00

abstract：:Background: Compared with trivalent influenza vaccines, quadrivalent influenza vaccines are expected to provide wider protection against influenza B virus infections. We developed a novel quadrivalent subunit influenza vaccine which was distinct from the influenza vaccines available on the market in production process...

journal_title：Human vaccines & immunotherapeutics

authors： Ye H,Jia S,Zhang Y,Li J,Zhu F

更新日期：2020-11-01 00:00:00

abstract：:The rapid evolution of influenza A viruses poses a great challenge to vaccine development. Analytical and machine learning models have been applied to facilitate the process of antigenicity determination. In this study, we designed deep convolutional neural networks (CNNs) to predict Influenza antigenicity. Our model ...

journal_title：Human vaccines & immunotherapeutics

authors： Lee EK,Tian H,Nakaya HI

更新日期：2020-11-01 00:00:00

abstract：:The currently available drugs to treat hepatitis B virus (HBV) infection include interferons and nucleos(t)ide analogs, which can only induce disease remission and are inefficient for the functional cure of patients with chronic HBV infection (CHB). Since high titers of circulating hepatitis B surface antigen (HBsAg) ...

journal_title：Human vaccines & immunotherapeutics

authors： Gao Y,Zhang TY,Yuan Q,Xia NS

更新日期：2017-08-03 00:00:00

abstract：:This study aimed to describe the disparities in immunization coverage between National Immunization Program (NIP) vaccines and non-NIP vaccines in Yiwu and to identify potential determinants. A face-to-face interview-based questionnaire survey among 423 migrant children born from 1 June 2010 to 31 May 2013 was conduct...

journal_title：Human vaccines & immunotherapeutics

authors： Hu Y,Luo S,Tang X,Lou L,Chen Y,Guo J

更新日期：2015-01-01 00:00:00

abstract：:H5N1 influenza candidate vaccine viruses were developed using the "6+2" approach. The hemagglutinin (HA) and neuraminidase (NA) genes were derived from the popular H5N1 virus and the remaining six internal segments were derived from the A/Puerto Rico/8/34 strain (H1N1, PR8). However, some of these candidate strains ha...

journal_title：Human vaccines & immunotherapeutics

authors： Pan W,Dong Z,Meng W,Zhang W,Li T,Li C,Zhang B,Chen L

更新日期：2012-02-01 00:00:00

abstract：INTRODUCTION:It is unclear what role daughters play in the decision-making process regarding HPV vaccination. Therefore, we explored the impact of HPV vaccination intention among parents and their 12-13 year-old daughters on HPV vaccination uptake. METHODS:In February 2014 parents/guardians and their 12-13 year-old da...

journal_title：Human vaccines & immunotherapeutics

authors： Jongen VW,van der Loeff MFS,Boyd A,Petrignani M,Prins M,van der Wal M,Nielen A,de Melker H,Paulussen TGWM,Alberts CJ

更新日期：2020-09-23 00:00:00

abstract：:Novel coronavirus disease 2019 (COVID-19) is caused by the SARS-CoV-2 virus, which belongs to the genus Coronaviridae with its high mutation rate. From the current perspective, we discuss the current status of COVID-19, new challenges, and potential interventions to control the pandemic in developing counties such as ...

journal_title：Human vaccines & immunotherapeutics

authors： Anjum FR,Anam S,Rahman SU

更新日期：2020-10-02 00:00:00

abstract：:Dengue is prevalent in the Asia-Pacific region. Participants of two immunogenicity and safety phase II studies conducted in Singapore and Vietnam (NCT0088089 and NCT00875524, respectively) were followed for up to four years after third vaccine dose of a recombinant, live, attenuated, tetravalent dengue vaccine (CYD-TD...

journal_title：Human vaccines & immunotherapeutics

authors： Tran NH,Chansinghakul D,Chong CY,Low CY,Shek LP,Luong CQ,Fargo C,Wartel TA,Sun S,Skipetrova A,Bouckenooghe A

更新日期：2019-01-01 00:00:00