Abstract:
:Randomized controlled trials (RCTs), typically, randomize participants to one of two intervention groups. It has been shown, however, that about 25% of RCTs published in the scientific literature randomize participants to three or more treatment groups. These studies are called 'multi-arm' trials: there may be, for instance, two or more experimental intervention groups with a common control group, or two control intervention groups such as a placebo group and a standard treatment group. A special case of multi-arm studies are factorial trials, which address two or more intervention comparisons carried out simultaneously, using four or more intervention groups.
journal_name
Epidemiol Psychiatr Scijournal_title
Epidemiology and psychiatric sciencesauthors
Cipriani A,Barbui Cdoi
10.1017/S2045796013000231subject
Has Abstractpub_date
2013-09-01 00:00:00pages
213-5issue
3eissn
2045-7960issn
2045-7979pii
S2045796013000231journal_volume
22pub_type
杂志文章abstract:AIMS:High heterogeneity was found in the prevalence rates of mental disorders in adult asylum seekers and refugees in high-income countries. This may be related to different problems. Among them, there is a changing exposure to risk and protective factors for mental health at different phases of these people's life bef...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S204579601900057X
更新日期:2019-10-02 00:00:00
abstract::Psychiatry is having a great time. Over the last few years, we have seen an exceptional explosion in neuroscience knowledge, and especially in our understanding of the molecular mechanisms through which environmental and genetic factors affect the brain and regulate behaviour, while at the same interacting with periph...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S204579601500089X
更新日期:2016-04-01 00:00:00
abstract:AIMS:The association between Kawasaki disease (KD) and Attention deficit hyperactivity disorder (ADHD) has rarely been studied. In this study, we investigated the hypothesis that KD may increase the risk of ADHD using a nationwide Taiwanese population-based claims database. METHODS:Our study cohort consisted of patien...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796015000840
更新日期:2016-12-01 00:00:00
abstract::A recent meta-analysis of antidepressant trials is the largest conducted to date. Although it claims to prove antidepressant effectiveness beyond dispute, the main outcome is response rates, which are derived from continuous data in a process that can inflate differences between groups. The standardised mean differenc...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796018000240
更新日期:2018-10-01 00:00:00
abstract::With cancer incidence increasing over time worldwide, attention to the burden of psychiatric and psychosocial consequences of the disease is now mandatory for both cancer and mental health care professionals. Psychiatric disorders have been shown to affect at least 30-35% of cancer patients during all phases of the di...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796019000866
更新日期:2020-01-09 00:00:00
abstract::Aims. To assess the breadth of mental and substance coverage in the Cochrane review system. Methods. All mental health and substance entries were identified from the 2005 to April 2012 Cochrane Database of Systematic Reviews. Results. A total of 1019 entries focused on mental health or substance misuse, with 698 (68.5...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章,评审
doi:10.1017/S2045796012000455
更新日期:2013-06-01 00:00:00
abstract::In July 2015, the Canadian Agency for Drugs and Technologies in Health (CADTH) released a Rapid Response report summary, with a critical appraisal, on discontinuation strategies for patients with long-term benzodiazepines (BDZ) use. The CADTH document is a review of the literature. It includes studies whose interventi...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796016000032
更新日期:2016-06-01 00:00:00
abstract::This editorial discusses the application of a novel brain imaging analysis technique in the assessment of neuroanatomical dysconnectivity in psychotic illnesses. There has long been a clinical interest in psychosis as a disconnection syndrome. In recent years graph theory metrics have been applied to functional and st...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796015000074
更新日期:2015-08-01 00:00:00
abstract::Background. Interest in features of our local environments that may promote better mental health and wellbeing continues to rise among decision makers. Our purpose was to highlight a selection of these challenges and some promising avenues for enhancing the quality of evidence. Method. An analysis of approximately 267...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S204579601400050X
更新日期:2015-02-01 00:00:00
abstract::Diffusion tensor imaging (DTI) is a neuroimaging technique with a potential to elucidate white matter integrity. Recently, it has been used in the field of psychiatry to further understand the pathophysiology of major diseases, including bipolar disorder (BD). This review sought to focus on existing DTI findings on wh...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/s2045796011000229
更新日期:2011-06-01 00:00:00
abstract:AIM:Previous work suggests that the Dutch variant of assertive community treatment (ACT), known as Function ACT (FACT), may be effective in increasing symptomatic remission rates when replacing a system of hospital-based care and separate community-based facilities. FACT guidelines propose a different pattern of psychi...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/s2045796011000369
更新日期:2011-09-01 00:00:00
abstract:AIM:Eating disorders have increasingly become a public health concern globally. This study aimed to reveal the burden of eating disorders at the global, regional and national levels using the Global Burden of Disease (GBD) Study 2017 data. METHODS:We extracted the age-standardised rates (ASRs) of prevalence and disabi...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796020001055
更新日期:2020-12-07 00:00:00
abstract::Mental health care in the second half of the 20th century in much of the developed world has been dominated by the move out from large asylums. Both in response to this move and to make it possible, a pattern of care has evolved which is most commonly referred to as 'Community Psychiatry'. This narrative review descri...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796014000560
更新日期:2014-12-01 00:00:00
abstract:AIMS:For nearly a century, the incidence of cancer in people with schizophrenia was lower than in the general population. In the recent decade, the relationship between cancer and schizophrenia has become obscured. Thus, we investigated the cancer risk among young and middle-aged patients with schizophrenia. METHODS:R...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796016000883
更新日期:2018-04-01 00:00:00
abstract::Autism spectrum disorder (ASD) is a neurodevelopmental disorder mainly characterised by deficits in social communication as well as by narrow patterns of behaviour and interests (American Psychiatric Association, 2013), often accompanied by language, intellectual and sensory impairments. The severity of these impairme...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796017000610
更新日期:2018-04-01 00:00:00
abstract:AIMS:Little is known about the potential health impact of police encounters despite a ubiquitous police presence in many disadvantaged urban environments. In this paper, we assess whether persistent or aggressive interactions with the police are associated with poor mental health outcomes in a sample of primarily low-i...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796019000015
更新日期:2019-02-05 00:00:00
abstract::Within mental health care, 'person-centredness' has been generally interpreted to convey a holistic approach with an attitude of respect for the individual and his/her unique experience and needs. Although it has been possible to demonstrate that professionals can acquire such skills through training, the impact on cl...
journal_title:Epidemiology and psychiatric sciences
pub_type: 社论
doi:10.1017/S2045796012000078
更新日期:2012-06-01 00:00:00
abstract::Aims. It is often assumed that psychiatric units at general hospitals attract less stigma than do specialized psychiatric hospitals, but so far this has not been examined empirically. Methods. We conducted a representative population survey in Germany (n = 2410) in order to compare attitudes towards psychiatric units ...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796012000510
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Aims of this study are to explore the associations of readmission to psychiatric hospital over time, to develop a statistical model for early readmission to psychiatric hospital and to assess the feasibility of predicting early readmission. METHOD:The sample comprised 7891 general psychiatric discharges in ...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796015000128
更新日期:2016-04-01 00:00:00
abstract:AIMS:This systematic review compiled evidence on interventions to reduce mental health-related stigma among medical and nursing students in low- and middle-income countries (LMICs). Primary outcomes were stigmatising attitudes and discriminatory behaviours. METHODS:Data collection included two strategies. First, previ...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796019000167
更新日期:2019-04-01 00:00:00
abstract:AIMS:To examine the impact of multiple psychiatric disorders over the lifetime on risk of mortality in the general population. METHODS:Data came from a random community-based sample of 1397 adults in Atlantic Canada, recruited in 1992. Major depression, dysthymia, panic disorder, generalised anxiety disorder and alcoh...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796018000859
更新日期:2019-02-04 00:00:00
abstract::This brief review encompasses the key findings of structural Magnetic Resonance Imaging (sMRI) research on amygdala volume in autism spectrum disorders (ASD). We also highlight the possible correlation between the autistic behavioural phenotype and amygdala alteration. ...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796013000346
更新日期:2013-12-01 00:00:00
abstract::Aims. Prevalence and covariates of subclinical psychosis have gained increased interest in the context of early identification and treatment of persons at risk for psychosis. Methods. We analysed 9829 adults representative of the general population within the canton of Zurich, Switzerland. Two psychosis syndromes, der...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796013000681
更新日期:2015-02-01 00:00:00
abstract::Aims Social workers report high levels of stress and have an increased risk for hospitalisation with mental diagnoses. However, it is not known whether the risk of work disability with mental diagnoses is higher among social workers compared with other human service professionals. We analysed trends in work disability...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796016000597
更新日期:2017-12-01 00:00:00
abstract::Depression in the elderly is common and exhibits a distinctive phenomenology, due to neurobiological, physiological, psychological and social changes related to ageing. Most elderly with depression are managed in primary health care. Although the number of scientific publications related to geriatric psychiatry has in...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章,评审
doi:10.1017/S204579601200025X
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:Population-based studies have identified that delusional-like experiences (DLEs) are common in the general population. While there is a large literature exploring the relationship between poor social support and risk of mental illness, there is a lack of empirical data examining the association of poor socia...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796011000862
更新日期:2012-06-01 00:00:00
abstract:AIMS:To determine the association between the sleep duration and the risk of all-cause mortality in adults. METHODS:A search strategy was conducted in the MEDLINE, CENTRAL, EMBASE and LILACS databases. Searches were also conducted in other databases and unpublished literature. Cohort studies were included without lang...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章,meta分析
doi:10.1017/S2045796018000379
更新日期:2019-10-01 00:00:00
abstract:AIMS:Few studies have compared time trends for the incidence of psychosis. To date, the results have been inconsistent, showing a decline, an increase or no significant change. As far as we know, no studies explored changes in prevalence of early risk factors. The aim of this study was to investigate differences in ear...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796016000123
更新日期:2017-06-01 00:00:00
abstract:AIMS:To study the potential use of child behaviour checklist (CBCL) 1.5-5 scales for the early identification of preschoolers at risk of autism. METHODS:CBCL scores of three groups of preschoolers were compared: (1) an experimental group of 101 preschoolers with autism spectrum disorder (ASD); (2) a control group of 9...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/s204579601100045x
更新日期:2011-12-01 00:00:00
abstract::When developing accessible, affordable and effective mental health systems, exchange of data between countries is an important moving force towards better mental health care. Unfortunately, health information systems in most countries are weak in the field of mental health, and comparability of data is low. Special in...
journal_title:Epidemiology and psychiatric sciences
pub_type: 社论
doi:10.1017/s2045796011000060
更新日期:2011-03-01 00:00:00