What is a factorial trial?

Abstract:

:Randomized controlled trials (RCTs), typically, randomize participants to one of two intervention groups. It has been shown, however, that about 25% of RCTs published in the scientific literature randomize participants to three or more treatment groups. These studies are called 'multi-arm' trials: there may be, for instance, two or more experimental intervention groups with a common control group, or two control intervention groups such as a placebo group and a standard treatment group. A special case of multi-arm studies are factorial trials, which address two or more intervention comparisons carried out simultaneously, using four or more intervention groups.

authors

Cipriani A,Barbui C

doi

10.1017/S2045796013000231

subject

Has Abstract

pub_date

2013-09-01 00:00:00

pages

213-5

issue

3

eissn

2045-7960

issn

2045-7979

pii

S2045796013000231

journal_volume

22

pub_type

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