Abstract：
:A certain number of filters have notable anti-inflammatory properties with percentage inhibition of PMA-induced edema in mice at over 70%. The question arose as to whether this effect was likely to continue after UV irradiation. It can be noted that 7 filters retain an equivalent anti-inflammatory effect before and after 2h of irradiation in a Suntest device (650 W/m(2)). For 9 filters, the anti-inflammatory effect decreases and for 5 filters, the anti-inflammatory effect increases. Various behaviors should be noted. 3 groups of substances can be distinguished: such as phenylbenzimidazole sulfonic acid which loses its anti-inflammatory character after irradiation (the percentage inhibition falls from 80 to 44%), oxybenzone which retains a constant anti-inflammatory character (89% inhibition before and after irradiation and also octyl methoxycinnamate which becomes very anti-inflammatory (with a percentage inhibition of 93%). The same phenomenon is observed in the case of commercial products. This should be made known as it can have a considerable impact on the results which are displayed on the packaging of sun products.
journal_name
Int J Pharmjournal_title
International journal of pharmaceuticsauthors
Couteau C,Couteau O,Chauvet C,Paparis E,Coiffard LJdoi
10.1016/j.ijpharm.2013.04.067subject
Has Abstractpub_date
2013-08-16 00:00:00pages
124-7issue
1-2eissn
0378-5173issn
1873-3476pii
S0378-5173(13)00368-2journal_volume
452pub_type
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