当前位置： SCI文献检索 > EUROPEAN JOURNAL OF PEDIATRICS期刊下所有文献 > Serum immunoreactive erythropoietin of children in health and disease.

Serum immunoreactive erythropoietin of children in health and disease.

Abstract：

:Serum immunoreactive erythropoietin (siEPO) was determined in cord serum from neonates (n = 97, gestational age 36-43 weeks), in healthy children from birth to adolescence (n = 260) and in children with haematological (n = 30), renal (n = 10) and congenital heart diseases (n = 70). In healthy children siEPO levels decreased after birth (geometric mean cord siEPO 35.6 mU/ml with 95% range of 17-56 mU/ml in eutrophic, nondistressed fetuses) and reached lowest values during the first 2 months (geometric mean siEPO 11.5 mU/ml). Thereafter siEPO levels increased slightly and were constant between 2 months and adolescence. The geometric mean siEPO for healthy children after birth was 18.8 mU/ml with 95% range of 7-47 mU/ml. These estimates were not significantly different from normal adult values. In newborns with fetal distress (n = 15) cord siEPO was significantly elevated (geometric mean 63.0 mU/ml; P less than 0.001). In children with haematological disease, siEPO and Hb concentration were inversely correlated (log siEPO (mU/ml) = 4.1-0.20 x Hb (g/dl); r = -0.62; P less than 0.0005). This relationship was significantly different in children with chronic renal failure (log siEPO (mU/ml) = 0.67 + 0.035 x Hb (g/dl); r = 0.50; P = 0.1). In children with heart disease the geometric mean siEPO was 19.2 mU/ml with 95% range 8-65 mU/ml for cyanotic (SaO2 less than 94%) and 17.7 mU/ml with 95% range of 12-36 mU/ml for acyanotic patients. In this group siEPO values were inversely correlated to the arterial oxygen content (log siEPO (mU/ml) = 1.61-2.04 x oxygen content (l/l); r = -0.28; P less than 0.02).

journal_name

Eur J Pediatr

journal_title

European journal of pediatrics

authors

Eckardt KU,Hartmann W,Vetter U,Pohlandt F,Burghardt R,Kurtz A

doi

10.1007/BF01959395

subject

Has Abstract

pub_date

1990-04-01 00:00:00

pages

459-64

issue

7

eissn

0340-6199

issn

1432-1076

journal_volume

149

pub_type

杂志文章

相关文献

EUROPEAN JOURNAL OF PEDIATRICS文献大全
  • Abbreviated oesophageal pH monitoring in infants.

    abstract：:The results of 24 h oesophageal pH monitoring, performed in 129 infants aged 6-10 weeks, were compared to those in the same patients after shorter periods (3, 6, 9 and 12 h). In the investigated population there was no significant difference between the reflux index (percentage of time with a pH < 4.0) after 12 or 24 ...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF01959212

    authors： Vandenplas Y,Casteels A,Naert M,Derde MP,Blecker U

    更新日期：1994-02-01 00:00:00

  • A child with mental retardation and asymmetrical hypertrophy of limbs.

    abstract：:A 5-year-old male child presented with progressively increasing asymmetrical overgrowth of limbs, hyperpigmentation on the right half of the body, and mental retardation since 9 months of age. ...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-010-1346-9

    authors： Sethi SK,Yadav D,Garg P,Chawla J,Goyal D

    更新日期：2011-06-01 00:00:00

  • Neonatal suppurative parotitis: a vanishing disease?

    abstract：:A case of neonatal suppurative parotitis due to Klebsiella pneumoniae is described. This is the first case reported in the last 20 years. Infection with unusual microorganisms should be taken into account when planning antibiotic treatment, especially in hospital acquired infections of the salivary glands in the newbo...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF01957226

    authors： Coban A,Ince Z,Uçsel R,Ozgeneci A,Can G

    更新日期：1993-12-01 00:00:00

  • Diaphragmatic hernia in a female newborn with focal dermal hypoplasia and marked asymmetric malformations (Goltz-Gorlin syndrome).

    abstract：:We report a female newborn with focal dermal hypoplasia (Goltz-Gorlin Syndrome) and marked asymmetric malformations on the right side of the body. Diaphragmatic hernia on the same side, which has not been reported in this syndrome, led to perinatal complications. ...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF00538945

    authors： Kunze J,Heyne K,Wiedemann HR

    更新日期：1979-06-28 00:00:00

  • Total parenteral nutrition associated cholestasis: a predisposing factor for sepsis in surgical neonates?

    abstract：:Of 496 neonates and infants less than 1 year of age admitted to the paediatric surgical intensive care unit (PSICU) over a 5 year period (1983-1987), 94 required total parenteral nutrition (TPN) for more than 14 consecutive days, generally due to congenital anomalies of the digestive tract. Cholestasis occurred in 15 ...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF02171565

    authors： Bos AP,Tibboel D,Hazebroek FW,Bergmeijer JH,van Kalsbeek EJ,Molenaar JC

    更新日期：1990-02-01 00:00:00

  • Clinical profile, viral load, management and outcome of neonates born to COVID 19 positive mothers: a tertiary care centre experience from India.

    abstract：:Despite rapidly evolving knowledge about COVID 19 infection, routes of perinatal COVID 19 transmission and viral load in mother neonate dyad remain uncertain. Data were analysed to describe the clinicodemographic profile and viral load in neonates born to COVID 19 positive mothers. Of 2947 deliveries, 69 mothers were ...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-020-03800-7

    authors： Anand P,Yadav A,Debata P,Bachani S,Gupta N,Gera R

    更新日期：2021-02-01 00:00:00

  • Alcohol and cigarette use among adolescents with type 1 diabetes.

    abstract：:In this study, we compare the prevalence of alcohol and cigarette use among Polish adolescents with type 1 diabetes mellitus (T1DM) (n = 209), aged 15-18 years, with that of a large cohort of their healthy peers, using standardized questionnaire used in the European School Survey Project on Alcohol and Drugs (ESPAD). ...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-017-2895-y

    authors： Hogendorf AM,Fendler W,Sierosławski J,Bobeff K,Węgrewicz K,Malewska KI,Przudzik MW,Szmigiero-Kawko M,Sztangierska B,Myśliwiec M,Szadkowska A,Młynarski WM

    更新日期：2017-06-01 00:00:00

  • Trichothiodystrophy without photosensitivity. Biochemical, ultrastructural and DNA repair studies.

    abstract：:A case of trichothiodystrophy (TTD) without photosensitivity is reported in an 8-year-old girl. Electron microscopic (EM) examination of the keratinocytes showed fibrillary bundles in the cytoplasm thinner and less electron dense than those of the normal cells and large membrane-bound vacuoles filled with granular-fil...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF00496431

    authors： Fois A,Balestri P,Calvieri S,Zampetti M,Giustini S,Stefanini M,Lagomarsini P

    更新日期：1988-05-01 00:00:00

  • Metabolic liver diseases presenting with neonatal cholestasis: at the crossroad between old and new paradigms.

    abstract：:Metabolic liver diseases (MLD) are an important group of disorders presenting with neonatal cholestasis (NC). The spectrum of liver involvement is wide and the presumptive diagnosis is traditionally based on clinical and laboratory findings. Recently, next-generation sequencing (NGS) panels have emerged as an appealin...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-019-03328-5

    authors： Moreira-Silva H,Maio I,Bandeira A,Gomes-Martins E,Santos-Silva E

    更新日期：2019-04-01 00:00:00

  • Malignant thymoma in a patient with growth hormone deficiency during growth hormone therapy.

    abstract：:Malignant thymoma was found in an 8-year-old Japanese boy with growth hormone (GH) deficiency who had received GH therapy for 3 years and 5 months. There may be a possible relationship between the occurrence of malignant thymoma and GH therapy. ...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF02073374

    authors： Hasegawa T,Hasegawa Y,Koto S,Aso T,Tsuchiya Y,Hayashi A,Ishida H,Morikawa Y

    更新日期：1993-10-01 00:00:00

  • Haemorrhagic diathesis as a possible early sign of hereditary fructose intolerance.

    abstract：:An infant girl three weeks of age with the leading symptom of skin haemorrhages is presented. On further investigation, the signs of severe hepatic damage with hypofibrinogenaemia and prothrombin complex impairment, and renal tubular dysfunction were disclosed. All these pathological symptoms, which were reversed on f...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF00465567

    authors： Hosková A,Mrskos A

    更新日期：1977-12-30 00:00:00

  • In vivo propionate oxidation as a prognostic indicator in disorders of propionate metabolism.

    abstract：:Biochemical markers such as plasma and urinary metabolite concentrations and in vitro enzyme activity are of limited prognostic value in the most common disorders of propionate metabolism, methylmalonic acidaemia (MMA) and propionic acidaemia (PA). In vivo propionate oxidation was compared with conventional prognostic...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF02009661

    authors： Thompson GN,Walter JH,Bresson JL,Bonnefont JP,Saudubray JM,Leonard JV,Halliday D

    更新日期：1990-03-01 00:00:00

  • Triple A syndrome: 32 years experience of a single centre (1977-2008).

    abstract：:Triple A syndrome is an autosomal recessive disorder characterized by alacrima, achalasia, ACTH-resistant adrenal insufficiency, autonomic dysfunction, and neurodegeneration. Mutations in the AAAS gene on chromosome 12q13 encoding the nuclear pore protein ALADIN have been reported in these patients. Over the period 19...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-010-1222-7

    authors： Milenkovic T,Zdravkovic D,Savic N,Todorovic S,Mitrovic K,Koehler K,Huebner A

    更新日期：2010-11-01 00:00:00

  • Predicting nasal high-flow therapy failure by pediatric respiratory rate-oxygenation index and pediatric respiratory rate-oxygenation index variation in children.

    abstract：:The primary objective of this study was to evaluate whether pediatric respiratory rate-oxygenation index (p-ROXI) and variation in p-ROXI (p-ROXV) can serve as objective markers in children with high-flow nasal cannula (HFNC) failure. In this prospective, single-center observational study, all patients who received HF...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-020-03847-6

    authors： Yildizdas D,Yontem A,Iplik G,Horoz OO,Ekinci F

    更新日期：2020-10-19 00:00:00

  • Immunoglobulin deficiency with increased immunoglobulin M in three siblings: effect of long-term immunoglobulin therapy.

    abstract：:Diagnosis of immunoglobulin deficiency with increased IgM (hyper-IgM syndrome) was made in three siblings (two girls and a boy) on the basis of history, physical findings, and laboratory data. The prominent clinical findings were recurrent viral and bacterial infections of the respiratory tract. The most severe infect...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF00441406

    authors： Maródi L,Szabó I,Kalmár A

    更新日期：1988-12-01 00:00:00

  • Gray hair and acrodermatitis enteropathica-like dermatitis: an unexpected presentation of cystic fibrosis.

    abstract：:Presentation of cystic fibrosis (CF) with an acrodermatitis enteropathica-like skin rash, anemia, and hypoproteinemia without pulmonary disease is rarely reported before. We describe an 11-month-old boy with rash and edema as the presenting signs of cystic fibrosis. The interesting additional finding in our patient wa...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-011-1447-0

    authors： Dalgic B,Egritas O

    更新日期：2011-10-01 00:00:00

  • Subependymal pseudocysts in the neonate.

    abstract：:Serial ultrasound examinations were performed through the anterior fontanelle to detect and follow subependymal pseudocysts (SP) in 19 neonates without severe malformations. A high-resolution real-time sector scanner was employed. In 8 cases the SP involved both lateral ventricles, in 11 cases they were unilateral and...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF00595915

    authors： Zorzi C,Angonese I

    更新日期：1989-02-01 00:00:00

  • Unexpected side-effects of inhaled steroids: a case report.

    abstract：:An asthmatic child is presented who developed a cushingoid appearance with evidence of adrenal suppression and growth impairment while on low dose inhaled topical steroids. When the inhaled steroids were replaced by inhaled sodium cromoglycate his adrenal function recovered while his appearance and growth returned to ...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF02093730

    authors： Priftis K,Everard ML,Milner AD

    更新日期：1991-04-01 00:00:00

  • Skinfold measurements in children with cystic fibrosis: monitoring fat-free mass and exercise effects.

    abstract：UNLABELLED:Monitoring fat free mass (FFM), an indicator of nutritional status and a predictor of exercise performance in children, is particularly important in patients with cystic fibrosis (CF). We assessed validity of the skinfold method for measuring FFM, and its changes with exercise training, in children with CF. ...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s004310051209

    authors： de Meer K,Gulmans VA,Westerterp KR,Houwen RH,Berger R

    更新日期：1999-10-01 00:00:00

  • Correction to: Cost-effectiveness of rule-based immunoprophylaxis against respiratory syncytial virus infections in preterm infants.

    abstract：:The name of the co-author Wendy J. Ungar was inadvertently omitted on the original published article. Her name and affiliation have now been added to the author list. ...

    journal_title：European journal of pediatrics

    pub_type： 已发布勘误

    doi：10.1007/s00431-019-03526-1

    authors： Blanken MO,Frederix GW,Ungar WJ,Nibbelke EE,Koffijberg H,Sanders EAM,Rovers MM,Bont L,Dutch RSV Neonatal Network.

    更新日期：2020-02-01 00:00:00

  • Ethical issues about the paradigm shift in the treatment of children with trisomy 18.

    abstract：:Until recently, trisomy 18 was considered a disease incompatible with life, with a high percentage of electively terminated pregnancies. The usual behavior was denial of treatment. But some medical interventions have changed the survival of children. A search for articles published in the PubMed database on the latest...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章,评审

    doi：10.1007/s00431-019-03531-4

    authors： Silberberg A,Robetto J,Grimaux G,Nucifora L,Moreno Villares JM

    更新日期：2020-03-01 00:00:00

  • Hyaline membrane disease: prognostic factors and medium-term follow-up.

    abstract：:One hundred and twenty two cases of severe hyaline membrane disease are reported. 68 of them survived (57%). Adverse clinical, radiological and laboratory factors, and their effects on the early mortality rate, are analysed with particular reference to the referring centers, delay in admission, transport and the criti...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF00442059

    authors： Goenen M,Ninane J,Ducoffre B,Declerck Y,Claus D,Ferriere G,Thomas-van Moerbeke RM,Moulin D,De Meyer R,Tremouroux J

    更新日期：1978-03-13 00:00:00

  • COVID-19 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children and adolescents: a systematic review of critically unwell children and the association with underlying comorbidities.

    abstract：:Data show that children are less severely affected with SARS-Covid-19 than adults; however, there have been a small proportion of children who have been critically unwell. In this systematic review, we aimed to identify and describe which underlying comorbidities may be associated with severe SARS-CoV-2 disease and de...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章,评审

    doi：10.1007/s00431-020-03801-6

    authors： Williams N,Radia T,Harman K,Agrawal P,Cook J,Gupta A

    更新日期：2020-09-10 00:00:00

  • Aetiological heterogeneity of asymptomatic hyperglycaemia in children and adolescents.

    abstract：INTRODUCTION:Randomly estimated fasting hyperglycaemia in an asymptomatic individual may represent the first sign of pancreatic beta-cell dysfunction. OBJECTIVE:We aimed at specifying the genetic aetiology of asymptomatic hyperglycaemia in a cohort of children and adolescents. SUBJECTS AND METHODS:We analysed the aet...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-006-0106-3

    authors： Feigerlová E,Pruhová S,Dittertová L,Lebl J,Pinterová D,Kolostová K,Cerná M,Pedersen O,Hansen T

    更新日期：2006-07-01 00:00:00

  • Presumptive varicella vaccination is warranted in Greek adolescents lacking a history of disease or household exposure.

    abstract：:Current practice favors serotesting adolescents with a negative history of chickenpox rather than offering presumptive vaccination. Recent epidemiologic data from Greece indicate that a high proportion of adolescents (21.5%) are susceptible to chickenpox. We assessed the reliability of negative varicella history in re...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-008-0701-6

    authors： Katsafadou A,Kallergi K,Ferentinos G,Goulioti T,Foustoukou M,Papaevangelou V

    更新日期：2009-01-01 00:00:00

  • Insulin-like growth factors in lysosomal storage disease.

    abstract：:Recent data indicate that insulin-like growth factor II (IGF II) and lysosomal enzymes bind to a common receptor. We measured serum IGF I and II levels in 16 patients with various lysosomal storage disorders. The IGF serum concentrations were normal as long as no marked liver disease was present. Under these condition...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF02073885

    authors： Jaeggi-Groisman SE,Kiess W,Christomanou H,Kessler U,Froesch ER

    更新日期：1992-01-01 00:00:00

  • A fatal case of portal hypertension complicating systemic mastocytosis in an adolescent.

    abstract：:Portal hypertension was observed in a 17-year-old girl with urticaria pigmentosa since 2 months of age. Liver biopsies showed portal and sinusoidal infiltration with mast cells although spleen biopsies showed only fibrosis. CONCLUSION. Portal hypertension is a complication of systemic mastocytosis that can lead to dea...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF01959789

    authors： Fonga-Djimi HS,Gottrand F,Bonnevalle M,Farriaux JP

    更新日期：1995-10-01 00:00:00

  • Delta1-pyrroline-5-carboxylate synthase deficiency: neurodegeneration, cataracts and connective tissue manifestations combined with hyperammonaemia and reduced ornithine, citrulline, arginine and proline.

    abstract：UNLABELLED:Delta1-pyrroline-5-carboxylate synthase (P5CS) catalyses the reduction of glutamate to Delta1-pyrroline-5-carboxylate, a critical step in the biosynthesis of proline, ornithine and arginine. Recently, we reported a newly recognised inborn error due to deficiency of P5CS in two sibs, one presenting at birth w...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-004-1545-3

    authors： Baumgartner MR,Rabier D,Nassogne MC,Dufier JL,Padovani JP,Kamoun P,Valle D,Saudubray JM

    更新日期：2005-01-01 00:00:00

  • Hepatotoxicity of rifampicin and isoniazid in children treated for tuberculosis.

    abstract：:In order to determine the hepatotoxicity of rifampicin in children treated for tuberculosis, a survey was performed of 18 children receiving this medicine in combination with isoniazid. Fifteen of the 18 children (83%) showed a rise in ASAT values and 11 (61%) in ALAT values exceeding 29U/L. Seven children with maxima...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF00441477

    authors： Linna O,Uhari M

    更新日期：1980-09-01 00:00:00

  • Neonatal pneumothorax drainage systems: in vitro evaluation.

    abstract：:We studied, in vitro, different commercially available components for pneumothorax drainage, i.e. drainage tubes, Heimlich flutter valve and vacuum control units. The drainage of a pneumothorax by a drainage tube was, as expected, directly dependent on Poiseuille's law and was influenced more by diameter than length. ...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF02024337

    authors： Bakker JC,Liem M,Wijnands JB,Karsdon J,Berger HM

    更新日期：1989-10-01 00:00:00