Abstract:
:Current practice favors serotesting adolescents with a negative history of chickenpox rather than offering presumptive vaccination. Recent epidemiologic data from Greece indicate that a high proportion of adolescents (21.5%) are susceptible to chickenpox. We assessed the reliability of negative varicella history in relation to type of exposure in 311 children and 283 adolescents. In children with social or unknown exposure to varicella, a negative history had a high negative predictive value (NPV = 73.5), supporting the clinical practice of presumptive vaccination. Conversely, children with a negative history and household exposure had a low NPV (13.8), suggesting that pre-vaccination serologic testing is warranted. In conclusion, based on our local epidemiologic data, presumptive varicella vaccination should be offered to all adolescents with the exception of the subgroup of adolescents with household exposure.
journal_name
Eur J Pediatrjournal_title
European journal of pediatricsauthors
Katsafadou A,Kallergi K,Ferentinos G,Goulioti T,Foustoukou M,Papaevangelou Vdoi
10.1007/s00431-008-0701-6subject
Has Abstractpub_date
2009-01-01 00:00:00pages
23-5issue
1eissn
0340-6199issn
1432-1076journal_volume
168pub_type
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