Association of inflammatory factors with macular edema in branch retinal vein occlusion.

abstract：Importance:Anti-vascular endothelial growth factor (anti-VEGF) is a breakthrough treatment for wet age-related macular degeneration (wAMD), the most common cause of blindness in western countries. Anti-VEGF treatment prevents vision loss and has been shown to produce vision gains lasting as long as 5 years. Although th...

journal_title：JAMA ophthalmology

authors： Mulligan K,Seabury SA,Dugel PU,Blim JF,Goldman DP,Humayun MS

更新日期：2019-11-14 00:00:00

abstract：IMPORTANCE:The publication of the US Physician Payments Sunshine Act provides insight into the financial relationship between physicians and the pharmaceutical industry. This added transparency creates new opportunities of using objective data to better understand prior research that implicates pharmaceutical promotion...

journal_title：JAMA ophthalmology

authors： Taylor SC,Huecker JB,Gordon MO,Vollman DE,Apte RS

更新日期：2016-08-01 00:00:00

abstract：IMPORTANCE:Myopia (nearsightedness) has its onset in childhood and affects about one-third of adults in the United States. Along with its high prevalence, myopia is expensive to correct and is associated with ocular diseases that include glaucoma and retinal detachment. OBJECTIVE:To determine the best set of predictor...

journal_title：JAMA ophthalmology

authors： Zadnik K,Sinnott LT,Cotter SA,Jones-Jordan LA,Kleinstein RN,Manny RE,Twelker JD,Mutti DO,Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study Group.

更新日期：2015-06-01 00:00:00

abstract：IMPORTANCE:Patients and clinicians need to accurately assess the risks and benefits of pars plana vitrectomy for proliferative diabetic retinopathy, but clinical trial data may not reflect real-world experience. OBJECTIVE:To prospectively audit the complications of vitrectomy for proliferative diabetic retinopathy and...

journal_title：JAMA ophthalmology

authors： Jackson TL,Johnston RL,Donachie PH,Williamson TH,Sparrow JM,Steel DH

更新日期：2016-01-01 00:00:00

abstract：IMPORTANCE:The clinical features of the follicular subtype of ocular adnexal lymphoma (OAL) have not been previously evaluated in a large cohort. OBJECTIVE:To characterize the clinical features of follicular OAL. DESIGN, SETTING, AND PARTICIPANTS:We performed a retrospective multicenter study that involved 6 eye canc...

journal_title：JAMA ophthalmology

authors： Rasmussen PK,Coupland SE,Finger PT,Graue GF,Grossniklaus HE,Honavar SG,McKelvie P,Mulay K,Prause JU,Ralfkiaer E,Sjö LD,Heegaard S

更新日期：2014-07-01 00:00:00

abstract：Importance:After long-duration spaceflight, morphological changes in the optic nerve head (ONH) and surrounding tissues have been reported. Objective:To develop methods to quantify ONH and surrounding tissue changes using preflight and postflight optical coherence tomographic scans of the ONH region. Design, Setting,...

journal_title：JAMA ophthalmology

authors： Patel N,Pass A,Mason S,Gibson CR,Otto C

更新日期：2018-02-01 00:00:00

abstract：IMPORTANCE:Although anti-vascular endothelial growth factor treatment of neovascular age-related macular degeneration (AMD) results in improved vision overall, loss of substantial vision can occur. Understanding the processes that lead to loss of vision may lead to preventive strategies. OBJECTIVE:To determine the inc...

journal_title：JAMA ophthalmology

authors： Ying GS,Kim BJ,Maguire MG,Huang J,Daniel E,Jaffe GJ,Grunwald JE,Blinder KJ,Flaxel CJ,Rahhal F,Regillo C,Martin DF,CATT Research Group.

更新日期：2014-08-01 00:00:00

abstract：Importance:The Diabetic Retinopathy Clinical Research Network Protocol S randomized clinical trial results suggest that ranibizumab is a reasonable treatment alternative to panretinal photocoagulation (PRP) when managing proliferative diabetic retinopathy (PDR), with or without concomitant baseline diabetic macular ede...

journal_title：JAMA ophthalmology

authors： Hutton DW,Stein JD,Bressler NM,Jampol LM,Browning D,Glassman AR,Diabetic Retinopathy Clinical Research Network.

更新日期：2017-06-01 00:00:00

abstract：IMPORTANCE:To facilitate comparative clinical outcome research in low vision rehabilitation, we must use patient-centered measurements that reflect clinically meaningful changes in visual ability. OBJECTIVE:To quantify the effects of currently provided low vision rehabilitation (LVR) on patients who present for outpat...

journal_title：JAMA ophthalmology

authors： Goldstein JE,Jackson ML,Fox SM,Deremeik JT,Massof RW,Low Vision Research Network Study Group.

更新日期：2015-07-01 00:00:00

abstract：IMPORTANCE:There is a major lack of randomized controlled clinical trials evaluating the efficacy of prismatic treatments for hemianopia. Evidence for their effectiveness is mostly based on anecdotal case reports and open-label evaluations without a control condition. OBJECTIVE:To evaluate the efficacy of real relativ...

journal_title：JAMA ophthalmology

authors： Bowers AR,Keeney K,Peli E

更新日期：2014-02-01 00:00:00

abstract：Importance:Knowledge of the incidence and progression of diabetic retinopathy (DR) after gastric bypass surgery (GBP) in patients with obesity and diabetes could guide the management of these patients. Objective:To investigate the incidence of diabetic ocular complications in patients with type 2 diabetes after GBP co...

journal_title：JAMA ophthalmology

authors： Åkerblom H,Franzén S,Zhou C,Morén Å,Ottosson J,Sundbom M,Eliasson B,Svensson AM,Granstam E

更新日期：2021-01-14 00:00:00

abstract：IMPORTANCE:We describe a sign that can be used as a rapid and noninvasive adjunct to aid in the diagnosis of foveal hypoplasia. OBJECTIVE:To describe a concentric macular rings sign found on infrared reflectance (IRR) images in patients with foveal hypoplasia. DESIGN, SETTING, AND PATIENTS:We studied 13 patients with...

journal_title：JAMA ophthalmology

authors： Cornish KS,Reddy AR,McBain VA

更新日期：2014-09-01 00:00:00

abstract：IMPORTANCE:Progressive geographic atrophy (GA) of the retinal pigment epithelium leads to loss of central vision. To identify GA in age-related macular degeneration and assess treatment, correlation of function observed on microperimetry with structure observed on optical coherence tomographic (OCT) images may be of va...

journal_title：JAMA ophthalmology

authors： Pilotto E,Convento E,Guidolin F,Abalsamo CK,Longhin E,Parrozzani R,Midena E

更新日期：2016-08-01 00:00:00

abstract：Importance:The US Food and Drug Administration's medical device regulatory pathway was initially conceived with hardware devices in mind. The emerging market for ophthalmic digital devices necessitates an evolution of this paradigm. Objectives:To facilitate innovation in ophthalmic digital health with attention to saf...

journal_title：JAMA ophthalmology

authors： Bodnar ZM,Schuchard R,Myung D,Tarver ME,Blumenkranz MS,Afshari NA,Humayun MS,Morse C,Nischal K,Repka MX,Sprunger D,Trese M,Eydelman MB

更新日期：2019-06-06 00:00:00

abstract：IMPORTANCE:A large number of genes can cause inherited retinal degenerations when mutated. It is important to identify the cause of disease for a better disease prognosis and a possible gene-specific therapeutic intervention. OBJECTIVE:To identify the cause of disease in families with nonsyndromic retinitis pigmentosa...

journal_title：JAMA ophthalmology

authors： Shevach E,Ali M,Mizrahi-Meissonnier L,McKibbin M,El-Asrag M,Watson CM,Inglehearn CF,Ben-Yosef T,Blumenfeld A,Jalas C,Banin E,Sharon D

更新日期：2015-03-01 00:00:00

abstract：IMPORTANCE:Accurate assessment of disease burden and determination of disease progression are challenging in dry age-related macular degeneration (AMD). We assessed the utility of quantified fundus autofluorescence in (FAF) the evaluation and follow-up of dry AMD. OBJECTIVE:To develop a method for quantitative FAF ima...

journal_title：JAMA ophthalmology

authors： Schachar IH,Zahid S,Comer GM,Stem M,Schachar AG,Saxe SJ,Gardner TW,Elner VM,Jayasundera T

更新日期：2013-08-01 00:00:00

abstract：Importance:Although the association between suture colonization and postoperative infections remains hypothetical, measures to reduce perioperative suture colonization may minimize postoperative infections. The suture colonization rate in adjustable suture strabismus surgery is not well defined, and the effect of povid...

journal_title：JAMA ophthalmology

authors： Rossetto JD,Suwannaraj S,Cavuoto KM,Spierer O,Miller D,McKeown CA,Capo H

更新日期：2016-10-01 00:00:00

abstract：Importance:Congenital stationary night blindness (CSNB) implies a stable condition, with the major symptom being nyctalopia present at birth. Pediatric clinical presentation and the course of different genetic subtypes of CSNB have not, to our knowledge, been well described in the era of molecular genetic diagnosis. O...

journal_title：JAMA ophthalmology

authors： Miraldi Utz V,Pfeifer W,Longmuir SQ,Olson RJ,Wang K,Drack AV

更新日期：2018-04-01 00:00:00

abstract：IMPORTANCE:Few studies have been published on the association of the radiation dose received to the eyes during radiotherapy (RT) for childhood cancer and the risk for later cataract. OBJECTIVE:To investigate the risk for cataract after treatment of nonretinoblastoma solid cancer in childhood. DESIGN, SETTING, AND PA...

journal_title：JAMA ophthalmology

authors： Allodji RS,Diallo I,El-Fayech C,Kahlouche A,Dumas A,Schwartz B,Oberlin O,Benadjaoud MA,Labbé M,Jackson A,Bullet J,Rubino C,Haddy N,De Vathaire F

更新日期：2016-04-01 00:00:00

abstract：IMPORTANCE:We define a Reading Accessibility Index for evaluating reading in individuals with normal and low vision. OBJECTIVE:To compare the Reading Accessibility Index with data from the Impact of Cataracts on Mobility (ICOM) study. DESIGN, SETTING, AND PARTICIPANTS:This investigation was a secondary data analysis ...

journal_title：JAMA ophthalmology

authors： Calabrèse A,Owsley C,McGwin G,Legge GE

更新日期：2016-04-01 00:00:00

abstract：IMPORTANCE:The CX3CR1 gene is implicated as a candidate gene for age-related macular degeneration (AMD) through several lines of evidence. There is uncertainty, however, as to whether common genetic variants in CX3CR1 alter risk of AMD, since prior studies have been inconsistent and mostly limited to evaluation of 2 no...

journal_title：JAMA ophthalmology

authors： Schaumberg DA,Rose L,DeAngelis MM,Semba RD,Hageman GS,Chasman DI

更新日期：2014-01-01 00:00:00

abstract：IMPORTANCE:The effect of glaucoma on nonglaucomatous medical conditions and resultant secondary health care costs is not well understood. OBJECTIVE:To assess self-reported medical conditions, the use of medical services, and total health care costs among Medicare beneficiaries with glaucoma. DESIGN, SETTING, AND PART...

journal_title：JAMA ophthalmology

authors： Prager AJ,Liebmann JM,Cioffi GA,Blumberg DM

更新日期：2016-04-01 00:00:00

abstract：:IMPORTANCE Advanced glycation end products have been implicated in the pathogenesis of age-related macular degeneration (AMD). OBJECTIVE To investigate the relationship between serum carboxymethyllysine (CML), a major circulating advanced glycation end product, and AMD in older adults. DESIGN, SETTING, AND PARTICIPANT...

journal_title：JAMA ophthalmology

authors： Semba RD,Cotch MF,Gudnason V,Eiríksdottir G,Harris TB,Sun K,Klein R,Jonasson F,Ferrucci L,Schaumberg DA

更新日期：2014-04-01 00:00:00

abstract：IMPORTANCE:African American individuals are at high risk of diabetes mellitus and diabetic retinopathy but have suboptimal rates of dilated fundus examinations (DFEs). Early intervention is crucial for the prevention of diabetic retinopathy in this high-risk population. OBJECTIVE:To test the efficacy of behavioral act...

journal_title：JAMA ophthalmology

authors： Weiss DM,Casten RJ,Leiby BE,Hark LA,Murchison AP,Johnson D,Stratford S,Henderer J,Rovner BW,Haller JA

更新日期：2015-09-01 00:00:00

abstract：IMPORTANCE:Further research is crucial to better understand the reason for falls in individuals with visual impairment (VI) and to develop appropriate fall prevention strategies. OBJECTIVE:To compare balance measures in individuals with normal vision, VI, and uncorrected refractive error (URE). DESIGN AND SETTING:Cro...

journal_title：JAMA ophthalmology

authors： Willis JR,Vitale SE,Agrawal Y,Ramulu PY

更新日期：2013-08-01 00:00:00

abstract：Importance:Because studies have suggested that atropine might slow the progression of myopia in children, randomized clinical trials are warranted to understand this potential causal relationship. Objective:To evaluate the efficacy and safety of atropine, 0.01%, eyedrops on slowing myopia progression and axial elongat...

journal_title：JAMA ophthalmology

authors： Wei S,Li SM,An W,Du J,Liang X,Sun Y,Zhang D,Tian J,Wang N

更新日期：2020-10-01 00:00:00

abstract：Importance:Coronavirus disease 2019 (COVID-19) has been recognized as a pandemic by the World Health Organization. Whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can also infect tissues besides the respiratory system, such as the ocular tissues, remains unclear. Objective:To determine whether SAR...

journal_title：JAMA ophthalmology

authors： Yan Y,Diao B,Liu Y,Zhang W,Wang G,Chen X

更新日期：2020-10-08 00:00:00

abstract：Importance:Despite the existing country-specific strategies tackling social inequalities in visual health in adults, little is known about trends in visual function in childhood and its association with social position. Objective:To investigate the distribution of childhood visual function in the United Kingdom and as...

journal_title：JAMA ophthalmology

authors： Bountziouka V,Cumberland PM,Rahi JS

更新日期：2017-09-01 00:00:00

abstract：IMPORTANCE:The Standard of Care vs Corticosteroid for Retinal Vein Occlusion (SCORE) Study showed that intravitreal triamcinolone acetonide (IVTA) is effective at reducing macular edema and improving visual acuity in participants with retinal vein occlusion. Secondary analysis of the incidence, risk factors, and timing...

journal_title：JAMA ophthalmology

authors： Aref AA,Scott IU,Oden NL,Ip MS,Blodi BA,VanVeldhuisen PC,SCORE Study Investigator Group.

更新日期：2015-09-01 00:00:00

abstract：Importance:Mutations in the myocilin (MYOC) gene are the most common molecularly defined cause of primary open-angle glaucoma that typically occurs in patients with high intraocular pressures (IOP). One MYOC mutation, p.Gln368Ter, has been associated with as many as 1.6% of primary open-angle glaucoma cases that had a ...

journal_title：JAMA ophthalmology

authors： Alward WLM,van der Heide C,Khanna CL,Roos BR,Sivaprasad S,Kam J,Ritch R,Lotery A,Igo RP Jr,Cooke Bailey JN,Stone EM,Scheetz TE,Kwon YH,Pasquale LR,Wiggs JL,Fingert JH,NEIGHBORHOOD Consortium.

更新日期：2019-05-01 00:00:00