Abstract：
OBJECTIVE:The purpose of this study is to evaluate neuroprotective effect of sacral neuromodulation in rat spinal cord injury (SCI) model in the histological and functional aspects. METHODS:Twenty-one female Sprague Dawley rats were randomly divided into 3 groups : the normal control group (CTL, n=7), the SCI with sham stimulation group (SCI, n=7), and the SCI with electrical stimulation (SCI+ES, n=7). Spinal cord was injured by dropping an impactor from 25 mm height. Sacral nerve electrical stimulation was performed by the following protocol : pulse duration, 0.1 ms; frequency, 20 Hz; stimulation time, 30 minutes; and stimulation duration, 4 weeks. Both locomotor function and histological examination were evaluated as scheduled. RESULTS:The number of anterior horn cell was 12.3±5.7 cells/high power field (HPF) in the CTL group, 7.8±4.9 cells/HPF in the SCI group, and 6.9±5.5 cells/HPF in the SCI+ES group, respectively. Both the SCI and the SCI+ES groups showed severe loss of anterior horn cells and myelin fibers compared with the CTL group. Cavitation and demyelinization of the nerve fibers has no significant difference between the SCI group and the SCI+ES group. Cavitation of dorsal column was more evident in only two rats of SCI group than the SCI+ES group. The locomotor function of all rats improved over time but there was no significant difference at any point in time between the SCI and the SCI+ES group. CONCLUSION:In a rat thoracic spinal cord contusion model, we observed that sacral neuromodulation did not prevent SCI-induced myelin loss and apoptosis.
journal_name
J Korean Neurosurg Socjournal_title
Journal of Korean Neurosurgical Societyauthors
Lee CH,Hyun SJ,Yoon CY,Lim JY,Jahng TA,Kim KJdoi
10.3340/jkns.2012.52.6.509subject
Has Abstractpub_date
2012-12-01 00:00:00pages
509-12issue
6eissn
2005-3711issn
1598-7876journal_volume
52pub_type
杂志文章abstract：Objective:Electrooculography (EOG) records eyeball movements as changes in the potential difference between the negatively charged retina and the positively charged cornea. We aimed to investigate whether reliable EOG waveforms can be evoked by electrical stimulation of the oculomotor and abducens nerves during skull b...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2020.0179
更新日期：2020-12-23 00:00:00
abstract：:Penetrating cerebral injuries caused by foreign bodies occur rarely due to the substantial mechanical protection offered by the skull. Throughout most of history, the brain, residing in a "closed box" of bone, has not been vulnerable to external aggression. Recently, we encountered a serious penetrating craniocerebral...
journal_title：Journal of Korean Neurosurgical Society
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doi：10.3340/jkns.2014.56.6.537
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abstract：OBJECTIVE:Brainstem metastases are rarely operable and generally unresponsive to conventional radiation therapy or chemotherapy. Recently, Gamma Knife Radiosurgery (GKRS) was used as feasible treatment option for brainstem metastasis. The present study evaluated our experience of brainstem metastasis which was treated ...
journal_title：Journal of Korean Neurosurgical Society
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abstract：OBJECTIVE:To investigate the feasibility of C1 lateral mass screw and C2 pedicle screw with polyaxial screw and rod system supplemented with miniplate for interlaminar fusion to treat various atlantoaxial instabilities. METHODS:After posterior atlantoaxial fixation with lateral mass screw in the atlas and pedicle scre...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2012.52.2.120
更新日期：2012-08-01 00:00:00
abstract：OBJECTIVE:This 2009-2011 nation-wide study of adult Koreans was aimed to provide characteristics, medical utilization states, and survival rates for newly diagnosed patients with primary nonmalignant and malignant spine tumors. METHODS:Data for patients with primary spine tumors were selected from the Korean Health In...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2016.0505.011
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abstract：:Thoracic intramedullary schwannomas are rare spinal cord tumors. Most of these tumors have been reported as a single lesion in the spinal cord. The authors report the first case of intramedullary schwannoma accompanying by extramedullary beads-like daughter masses of the thoracic spine. A 68-year-old male presented wi...
journal_title：Journal of Korean Neurosurgical Society
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doi：10.3340/jkns.2011.49.5.302
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abstract：:Surgical treatment of the degenerative disc disease has evolved from traditional open spine surgery to minimally invasive spine surgery including endoscopic spine surgery. Constant improvement in the imaging modality especially with introduction of the magnetic resonance imaging, it is possible to identify culprit deg...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章,评审
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更新日期：2017-09-01 00:00:00
abstract：:Superior petrosal sinus (SPS) dural arteriovenous fistula (DAVF) is one of tentorial DAVFs with significant morbidity, which usually drains into the petrosal vein and its tributaries. Unless there is a connection with venous sinus, surgical obliteration is required. We present two cases of SPS DAVF which were successf...
journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2011.49.4.222
更新日期：2011-04-01 00:00:00
abstract：OBJECTIVE:This study characterized the neurons in the lumbosacral cord that express phospho ERK (pERK) after distension or irritation of the bladder, and their relation to the vanilloid receptor 1 (VR1) positive primary afferents. METHODS:Mechanical distension and chemical irritation of the bladder were induced by int...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2007.42.6.462
更新日期：2007-12-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2011.49.5.278
更新日期：2011-05-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2010.48.3.230
更新日期：2010-09-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2011.49.1.31
更新日期：2011-01-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2013.53.6.356
更新日期：2013-06-01 00:00:00
abstract：OBJECTIVE:Mechanical thrombectomy (MT) for acute intracranial internal carotid artery (ICA) occlusion is often complicated by difficult revascularization and non-involved territory embolization possibly related with larger clot-burden. This study aims to evaluate the efficacy of proximal aspiration thrombectomy (PAT) u...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2016.59.4.379
更新日期：2016-07-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2014.55.4.226
更新日期：2014-04-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2015.57.4.298
更新日期：2015-04-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2014.55.5.296
更新日期：2014-05-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2010.47.3.232
更新日期：2010-03-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2013.53.2.77
更新日期：2013-02-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2017.0404.001
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journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2009.46.3.265
更新日期：2009-09-01 00:00:00
abstract：:Diffuse intrinsic pontine glioma (DIPG) is a deadly paediatric brain cancer. Transient response to radiation, ineffective chemotherapeutic agents and aggressive biology result in rapid progression of symptoms and a dismal prognosis. Increased availability of tumour tissue has enabled the identification of histone gene...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章,评审
doi：10.3340/jkns.2018.0008
更新日期：2018-05-01 00:00:00
abstract：OBJECTIVE:The incidence of leptomeningeal dissemination from malignant glioma is rare, so the clinical features of this are not well documented yet. We attempted to determine the clinical features of leptomeningeal dissemination from malignant gliomas. METHODS:We retrospectively analyzed 11 cases of leptomeningeal dis...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2011.49.6.334
更新日期：2011-06-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2009.45.6.360
更新日期：2009-06-01 00:00:00
abstract：OBJECTIVE:To evaluate the feasibility and clinical and angiographic outcomes of stent-assisted embolization for complex middle cerebral artery (MCA) aneurysms. METHODS:The records of 23 consecutive patients with 24 MCA aneurysms, who underwent stent-assisted embolization of the aneurysm, were retrospectively evaluated...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2013.53.5.274
更新日期：2013-05-01 00:00:00
abstract：OBJECTIVE:The indications and optimal surgical treatments for intracranial cysts are controversial. In the present study, we describe long-term clinical and neuroimaging results of surgically treated intracranial cysts in children. The goal of this study is to contribute to the discussion of the debate. METHODS:This s...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2012.52.4.325
更新日期：2012-10-01 00:00:00
abstract：:Intracranial granulocytic sarcomas are rare tumors, which are composed of immature granulocytic cells. Although it has been well known that these tumors are associated with acute myeloblastic leukemia (AML), they have been almost always related to bone marrow relapse. However, isolated recurrence of granulocytic sarco...
journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2010.47.5.385
更新日期：2010-05-01 00:00:00
abstract：OBJECTIVE:The objectives of the present study were to characterize the natural course of initially non-operated traumatic acute subdural hematoma (ASDH) and to identify the risk factors of hematoma progression. METHODS:Retrospective analysis was performed using sequential computed tomography (CT) images maintained in ...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2013.54.3.211
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVE:Aneurysmal rebleeding is a major cause of death and disability. The aim of this study is to investigate the incidence of rebleeding, and the factors related with patient's outcome. METHODS:During a period of 12 years, from September 1995 to August 2007, 492 consecutive patients with aneurysmal subarachnoid h...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2010.47.2.119
更新日期：2010-02-01 00:00:00
