Abstract:
OBJECTIVE:The objectives of this study were to analyze the recanalization rates and outcomes of multimodal therapy that consisted of sequential intravenous (IV)/intra-arterial (IA) thrombolysis, mechanical thrombolysis including mechanical clot disruption using microcatheters and microwires, balloon angioplasty, and stenting for acute ischemic stroke, and to evaluate the prognostic factors related to the outcome. METHODS:Fifty patients who were admitted to the hospital within 8 hours from ischemic symptom onset were retrospectively analyzed. Initial IV thrombolysis and subsequent cerebral angiography were performed in all patients. If successful recanalization was not achieved by IV thrombolysis, additional IA thrombolysis with mechanical thrombolysis, including balloon angioplasty and stenting, were performed. The outcomes were assessed by the National Institute of Health Stroke Scale (NIHSS) change and modified Rankin scale (mRS) and prognostic factors were analyzed. RESULTS:Successful recanalization was achieved in 42 (84%) of 50 patients, which consisted of 8 patients after IV thrombolysis, 19 patients after IA thrombolysis with mechanical clot disruption, and 15 patients after balloon angioplasty or stenting. Symptomatic hemorrhage occurred in 4 (8%) patients. Good outcomes were achieved in 76% and 70% of patients upon discharge, and 93% and 84% of patients after 3 months according to the NIHSS change and mRS. The initial clinical status, recanalization achievement, and presence of symptomatic hemorrhage were statistically related to the outcomes. CONCLUSION:Multimodal therapy may be an effective and safe treatment modality for acute ischemic stroke. Balloon angioplasty and stenting is effective for acute thrombolysis, and produce higher recanalization rates with better outcomes.
journal_name
J Korean Neurosurg Socjournal_title
Journal of Korean Neurosurgical Societyauthors
Jeong SY,Park SS,Koh EJ,Eun JP,Choi HYdoi
10.3340/jkns.2009.45.6.360subject
Has Abstractpub_date
2009-06-01 00:00:00pages
360-8issue
6eissn
2005-3711issn
1598-7876journal_volume
45pub_type
杂志文章abstract::Superior petrosal sinus (SPS) dural arteriovenous fistula (DAVF) is one of tentorial DAVFs with significant morbidity, which usually drains into the petrosal vein and its tributaries. Unless there is a connection with venous sinus, surgical obliteration is required. We present two cases of SPS DAVF which were successf...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2011.49.4.222
更新日期:2011-04-01 00:00:00
abstract::Malignant peripheral nerve sheath tumors (MPNSTs) are very rare tumors. We experienced a case of MPNST in the cervical paraspinal space which was not associated with neurofibromatosis. The tumor located in left C6-7 foramen and compressed C7 root. The tumor was removed through the occipital triangle. We report a case ...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2008.44.2.91
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVE:Brainstem metastases are rarely operable and generally unresponsive to conventional radiation therapy or chemotherapy. Recently, Gamma Knife Radiosurgery (GKRS) was used as feasible treatment option for brainstem metastasis. The present study evaluated our experience of brainstem metastasis which was treated ...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2011.50.4.299
更新日期:2011-10-01 00:00:00
abstract::Various approaches have been attempted in translational moyamoya disease research. One promising material for modeling and treating this disease is vascular progenitor cells, which can be acquired and expanded from patient peripheral blood. These cells may provide a novel experimental model and enable us to obtain ins...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章,评审
doi:10.3340/jkns.2015.57.6.428
更新日期:2015-06-01 00:00:00
abstract::The demineralized bone matrix (DBM) as the bone graft material to increase the fusion rate was widely used in spinal fusion. The current study aimed to compare the fusion rate of DBM to the fusion rate of autograft in lumbar spine fusion via meta-analysis of published literature. After systematic search, comparative s...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2019.0185
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVE:Meningioma is the second most common primary central nervous system neoplasm. In contrast, chordoid meningioma is rare; due to the paucity of cases, little is known about its clinical features or treatment outcomes. The objectives of this study were to describe the clinical characteristics and outcomes for pa...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2014.56.3.194
更新日期:2014-09-01 00:00:00
abstract::We report two rare cases of spinal intraosseous schwannoma (SIS) with sustained myelopathy symptoms and provide an updated review regarding SIS in the literature. A 71-year-old man experienced right lumbocrural pain and gait disturbance accompanied with paresthesia and right leg weakness. Imaging examinations revealed...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2015.57.6.478
更新日期:2015-06-01 00:00:00
abstract::Cerebellar hemorrhage is an unusual complication of supratentorial neurosurgery. To the best of our knowledge, only three case reports have described the occurrence of cerebellar hemorrhage after burr hole drainage for the treatment of chronic subdural hematoma (SDH). We present the case of a patient with this rare po...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2009.46.6.592
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVE:The purpose of this study is to evaluate neuroprotective effect of sacral neuromodulation in rat spinal cord injury (SCI) model in the histological and functional aspects. METHODS:Twenty-one female Sprague Dawley rats were randomly divided into 3 groups : the normal control group (CTL, n=7), the SCI with sha...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2012.52.6.509
更新日期:2012-12-01 00:00:00
abstract:Objective:Although venous thromboembolism (VTE) is frequently related to dehydration, the impact of dehydration on VTE in acute ischemic stroke (AIS) is not clear. This study investigated whether dehydration, as measured by blood urea nitrogen (BUN)/creatinine (Cr) ratio, influences the occurrence of VTE in patients wi...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2016.1010.009
更新日期:2017-11-01 00:00:00
abstract::Mild traumatic brain injury is common in elderly patients, many of whom are on anticoagulant. The common practice is to discharge these patients from the emergency room if the computed tomography (CT) of the brain is normal. However, a very small proportion of these patients may develop a life threatening intracranial...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2014.55.1.51
更新日期:2014-01-01 00:00:00
abstract::We report a case of pedicle screw loosening treated by modified transpedicular screw augmentation technique using polymethylmethacrylate (PMMA), which used the anchoring effect of hardened PMMA. A 56-year-old man who had an L3/4/5 fusion operation 3 years ago complained of continuous low back pain after this operation...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2011.49.1.75
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:Perfusion computed tomography (PCT) has the ability to measure quantitative value and produce maps of mean transit time (MTT), cerebral blood flow (CBF), and cerebral blood volume (CBV). We assessed cerebral hemodynamics by using these parameters and acetazolamide (ACZ) challenge for pre- and post-procedural ...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2013.54.4.280
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVE:Repair of sensorial nerve defect is an important issue on peripheric nerve surgery. The aim of the present study was to determine the effects of sensory-motor nerve bridging on the denervated dermatomal area, in rats with sensory nerve defects, using a neural cell adhesion molecule (NCAM). METHODS:We compare...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2016.1010.010
更新日期:2017-07-01 00:00:00
abstract::The Chiari 1.5 malformation is defined as a tonsillar herniation within a Chiari I malformation with additional caudal descent of the brainstem through the foramen magnum. We describe a patient with Chiari I malformation who evolved to Chiari 1.5 malformation during longitudinal follow-up. A 15-year-old girl presented...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2010.48.4.375
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to examine the efficacy and safety of microvascular decompression (MVD) for hemifacial spasm (HFS) in elderly patients. METHODS:Between 1997 and June 2008, 1,174 patients had undergone MVD for HFS at our institute. Among these, 53 patients were older than 65 years. We retrospect...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2010.47.6.442
更新日期:2010-06-01 00:00:00
abstract::Plasma cell granuloma is a tumor-like disease characterized by non-neoplastic polyclonal proliferation of plasma cells and other mononuclear cells. This disease occurs most frequently in the lung and upper respiratory tract, while the involvement of the central nervous system is very rare. A 44-year-old female patient...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2009.46.2.161
更新日期:2009-08-01 00:00:00
abstract::Diffuse intrinsic pontine glioma (DIPG) is a deadly paediatric brain cancer. Transient response to radiation, ineffective chemotherapeutic agents and aggressive biology result in rapid progression of symptoms and a dismal prognosis. Increased availability of tumour tissue has enabled the identification of histone gene...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章,评审
doi:10.3340/jkns.2018.0008
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVE:Metaplastic meningioma is an extremely rare subtype of World Health Organization (WHO) grade I meningioma. It has distinctive histological subtypes according to its own mesenchymal components. Owing to its scarcity, clinical or radiological features of a metaplastic meningioma are poorly described. METHODS:B...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2020.0151
更新日期:2020-09-01 00:00:00
abstract::A case of intradural extramedullary cavernous angioma is presented with headache, dizziness, and bilateral sensorineural hearing loss caused by an intracranial superficial hemosiderosis. It was incidentally found in a patient with a 3-month history of sustained headache, dizziness and a 3-year history of hearing diffi...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2011.49.6.377
更新日期:2011-06-01 00:00:00
abstract::Traumatic brainstem hemorrhage after blunt head injury is an uncommon event. The most frequent site of hemorrhage is the midline rostral brainstem. The prognosis of these patients is poor because of its critical location. We experienced a case of traumatic brainstem hemorrhage. A 41-year-old male was presented with dr...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2009.45.3.176
更新日期:2009-03-01 00:00:00
abstract::Carotid occlusion is an inevitable therapeutic modality for the treatment of complex aneurysms such as giant, traumatic, and intracavernous aneurysms. Late complications of carotid occlusion include 'de novo' aneurysm formation at a distant site because of hemodynamic changes in the circle of Willis. We report a case ...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2009.45.4.236
更新日期:2009-04-01 00:00:00
abstract:OBJECTIVE:The objective of this study is to investigate clinical characteristics, management methods and possible causes of intracranial fusiform aneurysm. METHODS:Out of a series of 2,458 intracranial aneurysms treated surgically or endovascularly, 22 patients were identified who had discrete fusiform aneurysms. Clin...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2008.44.3.116
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:To examine the synergistic effects of both computer-assisted cognitive rehabilitation (CACR) and transcranial direct current stimulation (tDCS) on cognitive function in patients with stroke. METHODS:The current double-blind, sham-controlled study enrolled a total of 11 patients who were newly diagnosed with ...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2013.54.6.484
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the feasibility and clinical and angiographic outcomes of stent-assisted embolization for complex middle cerebral artery (MCA) aneurysms. METHODS:The records of 23 consecutive patients with 24 MCA aneurysms, who underwent stent-assisted embolization of the aneurysm, were retrospectively evaluated...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2013.53.5.274
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVE:The authors evaluated the accuracies and ease of use of several commonly used microanastomosis training models (synthetic tube, chicken wing, and living rat model). METHODS:A survey was conducted among neurosurgeons and neurosurgery residents at a workshop held in 2009 at the authors' institute. Questions ad...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2010.47.4.287
更新日期:2010-04-01 00:00:00
abstract:Objective:To explore the correlation between the polymorphism of histone deacetylase 9 gene (rs1060499865, rs723296, rs957960) and ischemic stroke (IS) in Chinese Han population in Dali region. Methods:This study included 155 IS patients and 128 healthy physical examinees. TaqMan-polymerase chain reaction technology a...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2020.0040
更新日期:2020-11-24 00:00:00
abstract::Acute subdural hematoma (SDH) of arterial origin is rare, especially SDH associated with an arteriovenous malformation (AVM) is extremely rare. The authors report a case of acute spontaneous SDH due to rupture of a tiny cortical AVM. A 51-year-old male presented with sudden onset headache and mentality deterioration w...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2015.58.6.547
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:To investigate the effects of posterior implant rigidity on spinal kinematics at adjacent levels by utilizing a cadaveric spine model with simulated physiological loading. METHODS:Five human lumbar spinal specimens (L3 to S1) were obtained and checked for abnormalities. The fresh specimens were stripped of m...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2015.58.5.412
更新日期:2015-11-01 00:00:00
abstract::A 55-year-old female patient presented with lower back pain and neurogenic intermittent claudication and underwent L3-L4 posterolateral fusion. To prepare the bone fusion bed, the transverse process of L3 and L4 was decorticated with a drill. On the 9th post-operative day, the patient complained of a sudden onset of s...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2013.54.4.344
更新日期:2013-10-01 00:00:00