Abstract:
:Attention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders among school-aged children. It is highly symptomatic and associated with significant impairment. This review examines the role of stimulant medications in the treatment of children and adolescents with ADHD. Published clinical studies that compared methylphenidate- and amfetamine-based stimulants in children and adolescents with ADHD support the therapeutic utility of stimulant treatments, and suggest robust efficacy and acceptable safety outcomes in groups treated with either stimulant. Evidence-based guidelines agree that each patient with ADHD is unique and individual treatment strategies that incorporate both drug and non-drug treatment options should be sought. In seeking to optimize individual response and outcomes to stimulant therapy, important considerations include the selection of stimulant class, the choice of long- or short-acting stimulant formulations, addressing effectively any emergent adverse effects and strategies aimed at enhancing adherence to dosing regimen and persistence on therapy.
journal_name
Eur Child Adolesc Psychiatryjournal_title
European child & adolescent psychiatryauthors
Hodgkins P,Shaw M,Coghill D,Hechtman Ldoi
10.1007/s00787-012-0286-5subject
Has Abstractpub_date
2012-09-01 00:00:00pages
477-92issue
9eissn
1018-8827issn
1435-165Xjournal_volume
21pub_type
杂志文章,评审abstract:BACKGROUND:Given the dosing limitations of methylphenidate short-acting preparations in treating ADHD, galenics with longer release of the substance were developed mainly to avoid drug intake during school hours. OBJECTIVES:This investigation was conducted to assess the efficacy and the duration of action of a new ext...
journal_title:European child & adolescent psychiatry
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1007/s00787-004-1009-3
更新日期:2004-01-01 00:00:00
abstract::Infant mental health problems include difficulties to regulate emotions or attention, crying, sleeping or feeding problems as well as aggressive behavior. Early identifications of these problems help to change developmental trajectories and improve developmental outcomes. Psychiatric assessment and classification have...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章,评审
doi:10.1007/s00787-012-0364-8
更新日期:2013-02-01 00:00:00
abstract::Community and nationwide surveys on adolescent suicidal behaviors using clinical interviews are not abundant. Rates of self-reported suicide attempts in community samples vary greatly between 1 and 20 %. In general, adolescent and parental agreement in child psychiatry practice is low, and their agreement with regard ...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-016-0862-1
更新日期:2016-12-01 00:00:00
abstract::Medically unexplained physical symptoms are frequently named by adolescents in both clinical and normative samples. This study analyzed the associations between parental rearing styles and adolescents' body complaints in diverse cultural contexts. In a cross-cultural study of 2415 adolescents from eight countries (Arg...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-020-01628-y
更新日期:2020-09-07 00:00:00
abstract::Metabolic control in adolescents with diabetes is difficult to achieve and seems to depend in part on personality and the family environment. We tried to identify relevant characteristics in this study. We administered the Children's Manifest Anxiety Scale, a Self-Competence scale, a Locus of Control Scale, and a stru...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/BF02091790
更新日期:1992-04-01 00:00:00
abstract::Twin studies described a strongly heritable component of attention-deficit/hyperactivity disorder (ADHD) in children and adolescents. However, findings varied considerably between studies. In addition, ADHD presents with a high rate of comorbid disorders and associated psychopathology. Therefore, this literature revie...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章,评审
doi:10.1007/s00787-010-0097-5
更新日期:2010-03-01 00:00:00
abstract::We compared the predictability of the behaviour of hyperactive children with that of aggressive children, combined hyperactive/aggressive children and normal children. Detailed behaviour measurements relating to each child and an experimenter were recorded during playroom session. Predictability was expressed in infor...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/BF00571673
更新日期:1996-09-01 00:00:00
abstract::It has been suggested that neurotrophins are involved in the etiopathogenesis of attention-deficit/hyperactivity disorder (ADHD). This study aimed to investigate whether there are differences in serum brain-derived neurotrophic factor (BDNF), glial-derived neurotrophic factor (GDNF), nerve growth factor (NGF), and neu...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-016-0898-2
更新日期:2017-03-01 00:00:00
abstract::Higher levels of anger expression, as well as lower levels of anger control, have been reported for adults with anxiety disorders compared to individuals without anxiety disorders. Different to the research on adults, very few studies examined the relationship between anxiety and anger in childhood. In our study, we i...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-020-01543-2
更新日期:2020-05-07 00:00:00
abstract::Sleep disturbances are common in the pediatric population and should primarily be treated non-pharmacologically. Most medicines for sleep disturbances are not approved for pediatric use and data on long-term safety is scarce. In Sweden, melatonin is classified as a prescription medicine. The aim of the present study w...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-020-01598-1
更新日期:2020-07-22 00:00:00
abstract::The link between attention deficit/hyperactivity disorder (ADHD) and elevated body weight/obesity can be regarded as well established. Because oppositional defiant disorder (ODD)/conduct disorder (CD) has also been found to be associated with these characteristics and ADHD and ODD/CD often occur comorbidly, we investi...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-013-0489-4
更新日期:2014-07-01 00:00:00
abstract::Little is known about the natural history of children with pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections (PANDAS). This study prospectively followed 33 children with PANDAS for up to 4.8 years (mean 3.3 ± 0.7 years) after enrollment in a 24-week randomized, double-blind, place...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00787-017-1077-9
更新日期:2018-05-01 00:00:00
abstract::A large number of investigation techniques are used to establish the relationships between the clinical and biological data which are necessary for physiopathological analysis in the field of developmental disorders. It therefore seemed necessary to develop a quantified grouping system, based on developmental assessme...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/BF01977740
更新日期:1995-04-01 00:00:00
abstract::Suicide is one of the leading causes of death in adolescents and help-seeking behaviour for suicidal behaviour is low. School-based screenings can identify adolescents at risk for suicidal behaviour and might have the potential to facilitate service use and reduce suicidal behaviour. The aim of this study was to asses...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-020-01681-7
更新日期:2020-12-15 00:00:00
abstract::This study investigates the prevalence and subtypes of conduct disorder (CD) and behavioral problems among youth in two communities characterized by prolonged parent-child separation upon immigration. CD and problem behaviors were assessed in 252 Caribbean-Canadian and Filipino-Canadian adolescents (12-19-year-old) us...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-007-0640-1
更新日期:2008-08-01 00:00:00
abstract::Children with social anxiety disorder (SAD) have been reported to display reduced social skills. Less attention has been paid to whether neurodevelopmental deficits/delays (NDD's) in language and motor function may contribute to their impaired social skills. The present study aimed to assess the extent of language and...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-007-0642-z
更新日期:2008-03-01 00:00:00
abstract::The objective of this study is to assess (1) the concordance and validity of schizophrenia register diagnoses among children and adolescents (early onset schizophrenia = EOS) in the Danish Psychiatric Central Research Register (DPCRR), and (2) the validity of clinical record schizophrenia diagnoses. Psychiatric record...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-017-1102-z
更新日期:2018-08-01 00:00:00
abstract::Half of mental disorders have their first onset before adulthood when the presence of a disorder may be particularly disruptive to developmental milestones. Retrospective prevalence estimates have been shown to underestimate the burden of mental illness and scarce data are available on the incidence of disorders throu...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-015-0721-5
更新日期:2016-02-01 00:00:00
abstract::Anorexia nervosa (AN) is frequently associated with symptoms of depression, anxiety, and obsessive-compulsive behavior which also develop secondary to semistarvation. It is less certain if these symptoms persist after recovery. A few studies have already reported on high prevalence rates of anxious, depressive, and ob...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-005-0431-5
更新日期:2005-03-01 00:00:00
abstract::Previous studies have demonstrated that many children with conduct problems (CP) also show internalising psychopathology (IP). However, it remains unclear whether the presence of IP serves as a protective or risk factor for the severity and development of CP. The aim of the present study was to assess the prevalence a...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-011-0229-6
更新日期:2012-01-01 00:00:00
abstract::Infants' temperamental anger or frustration reactions are highly stable, but are also influenced by maturation and experience. It is yet unclear why some infants high in anger or frustration reactions develop disruptive behavior problems whereas others do not. We examined family regularity, conceptualized as the consi...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-015-0797-y
更新日期:2016-07-01 00:00:00
abstract::The importance of paying attention to scale levels is emphasized and it is pointed out that Steven's hierarchy of ratio, interval, ordinal, and nominal scales is too narrow; other important scale properties have to be considered. For instance, sometimes a carefully constructed variable on a nominal scale contains more...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/BF00538540
更新日期:1996-01-01 00:00:00
abstract::This is the fourth and final study designed to develop International Classification of Functioning, Disability and Health (ICF, and children and youth version, ICF-CY) core sets for attention-deficit hyperactivity disorder (ADHD). To investigate aspects of functioning and environment of individuals with ADHD as docume...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章,多中心研究
doi:10.1007/s00787-018-1124-1
更新日期:2018-10-01 00:00:00
abstract::Nine people from the high functioning end of the autistic spectrum and eight non-handicapped controls matched on verbal IQ were given two tests of second-order false belief understanding. On the basis of previous research, it was hypothesised that the subjects with autism used different mechanisms to process mental st...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/BF00538988
更新日期:1997-09-01 00:00:00
abstract::Autistic spectrum disorders (ASD) are characterised by attention deficits in communication and social interactions and a lack of interest in people. Data are mostly based on clinical situations. However, recent studies have shown a more mixed situation where children with ASD (ASD children) displayed interest towards ...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-014-0528-9
更新日期:2015-01-01 00:00:00
abstract::Diagnostic categories of tic disorders include both transient and chronic tic disorders and Tourette's disorder. Changes for this group of disorders proposed for the forthcoming DSM-5 system include: (1) The term "stereotyped" will be eliminated in the definition of tics and the new definition will be applied consiste...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章,评审
doi:10.1007/s00787-012-0362-x
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVE:To investigate the prevalence of behavioural problems and autism in a population-based group of children with hydrocephalus and to see whether learning disabilities, cerebral palsy (CP), epilepsy, myelomeningocele (MMC) or preterm birth increase the risk of these problems. METHOD:In the 107 children with hyd...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-006-0525-8
更新日期:2006-06-01 00:00:00
abstract::Genetic epidemiological studies of Autism Spectrum Disorders (ASDs) based on twin pairs ascertained from the population and thoroughly assessed to obtain a high degree of diagnostic validity are few. All twin pairs aged 3-14 years in the nationwide Danish Twin Registry were approached. A three-step procedure was used....
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-013-0419-5
更新日期:2014-01-01 00:00:00
abstract::The developmental course of hyperactivity-impulsivity and inattention symptoms from infancy to adolescence has not been documented in a population sample. The aim of this study was to describe the developmental course of hyperactivity-impulsivity and inattention symptoms from 1.5 to 17 years using multiple informants,...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-018-1258-1
更新日期:2019-07-01 00:00:00
abstract::Academic impairment in individuals with attention-deficit/hyperactivity disorder (ADHD) is in part due to reduced motivation for academic tasks, which is likely to vary as a function of task characteristics. The current study employed a new questionnaire-the Child and Adolescent Motivational Profile (CHAMP)-to examine...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-020-01494-8
更新日期:2020-03-10 00:00:00