Abstract:
BACKGROUND:Although the initial robot-assisted radical prostatectomy (RARP) series showed 12-mo potency rates ranging from 70% to 80%, the few available comparative studies did not permit any definitive conclusion about the superiority of this technique when compared with retropubic radical prostatectomy (RRP) and laparoscopic radical prostatectomy (LRP). OBJECTIVES:The aims of this systematic review were (1) to evaluate the current prevalence and the potential risk factors of erectile dysfunction after RARP, (2) to identify surgical techniques able to improve the rate of potency recovery after RARP, and (3) to perform a cumulative analysis of all available studies comparing RARP versus RRP or LRP. EVIDENCE ACQUISITION:A literature search was performed in August 2011 using the Medline, Embase, and Web of Science databases. Only comparative studies or clinical series including >100 cases reporting potency recovery outcomes were included in this review. Cumulative analysis was conducted using Review Manager v.4.2 software designed for composing Cochrane Reviews (Cochrane Collaboration, Oxford, UK). EVIDENCE SYNTHESIS:We analyzed 15 case series, 6 studies comparing different techniques in the context of RARP, 6 studies comparing RARP with RRP, and 4 studies comparing RARP with LRP. The 12- and 24-mo potency rates ranged from 54% to 90% and from 63% to 94%, respectively. Age, baseline potency status, comorbidities index, and extension of the nerve-sparing procedure represent the most relevant preoperative and intraoperative predictors of potency recovery after RARP. Available data seem to support the use of cautery-free dissection or the use of pinpointed low-energy cauterization. Cumulative analyses showed better 12-mo potency rates after RARP in comparison with RRP (odds ratio [OR]: 2.84; 95% confidence interval [CI]: 1.46-5.43; p=0.002). Only a nonstatistically significant trend in favor of RARP was reported after comparison with LRP (OR: 1.89; p=0.21). CONCLUSIONS:The incidence of potency recovery after RARP is influenced by numerous factors. Data coming from the present systematic review support the use of a cautery-free technique. This update of previous systematic reviews of the literature showed, for the first time, a significant advantage in favor of RARP in comparison with RRP in terms of 12-mo potency rates.
journal_name
Eur Uroljournal_title
European urologyauthors
Ficarra V,Novara G,Ahlering TE,Costello A,Eastham JA,Graefen M,Guazzoni G,Menon M,Mottrie A,Patel VR,Van der Poel H,Rosen RC,Tewari AK,Wilson TG,Zattoni F,Montorsi Fdoi
10.1016/j.eururo.2012.05.046subject
Has Abstractpub_date
2012-09-01 00:00:00pages
418-30issue
3eissn
0302-2838issn
1873-7560pii
S0302-2838(12)00630-6journal_volume
62pub_type
杂志文章,meta分析,评审相关文献
EUROPEAN UROLOGY文献大全abstract:BACKGROUND:Recently, robot-assisted kidney transplantation (RAKT) was recently introduced as renal replacement mini-invasive surgery. OBJECTIVE:To report surgical technique, including tips and tricks, and the learning curve for RAKT. DESIGN, SETTING, AND PARTICIPANTS:All consecutive RAKTs performed in the five highes...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2019.12.008
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVE:To report our preliminary experience with trastuzumab (Herceptin) in the management of metastatic transitional cell carcinoma of the urinary tract. PATIENTS AND METHODS:From november 2001 to august 2002, six patients received trastuzumab for metastatic transitional cell carcinoma of the bladder (n=5) or rena...
journal_title:European urology
pub_type: 临床试验,杂志文章
doi:10.1016/j.eururo.2005.07.015
更新日期:2005-11-01 00:00:00
abstract:BACKGROUND:Laparoendoscopic single-site (LESS) radical prostatectomy (RP) has been performed through different approaches. A new DuoRotate manual system developed by Richard Wolf (KeyPort; Richard Wolf GmbH, Knittlingen, Germany) can be applied to RP. OBJECTIVES:Our aim was to describe the surgical technique and repor...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2012.04.043
更新日期:2012-12-01 00:00:00
abstract::The influence of magnesium chloride on various blood and urine parameters in calcium oxalate stone patients is studied. High dose magnesium therapy was found to increase urinary magnesium concentrations, whereas the oxalic acid concentration is reduced. The experiments support the statements on the role of magnesium i...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000473189
更新日期:1981-01-01 00:00:00
abstract:OBJECTIVE:A new surgical method of treating Peyronie's disease consisting in intracavernosal excision of the plaque is presented. MATERIAL AND METHODS:The operation was performed on 16 men aged from 34 to 65 years (mean 50.2 years). The angle of penile curvature was 30 degrees to 60 degrees. Thirteen (81.25%) had impa...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2003.05.001
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Perioperative cisplatin combination chemotherapy is associated with a survival benefit in patients with invasive bladder cancer (BCa). However, in a recent report from the National Cancer Database (NCDB), only 11.6% of stage III BCa patients received perioperative chemotherapy, the majority in the adjuvant s...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2008.07.018
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:The objective of the present study was to establish the therapeutic value of early coagulation of severe postoperative bleeding after transurethral prostate resection in unselected patients. PATIENTS AND METHODS:In a prospective study of 772 prostate resections carried out in 617 patients, bleeding complicat...
journal_title:European urology
pub_type: 临床试验,杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:A statistical model based on four kallikrein markers (total prostate-specific antigen [tPSA], free PSA [fPSA], intact PSA, and human kallikrein-related peptidase 2) in blood can predict risk of Gleason score ≥7 (high-grade) cancer at prostate biopsy. OBJECTIVE:To determine the value of this model in predict...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2015.04.028
更新日期:2016-03-01 00:00:00
abstract::During an 18-month period, 200 male infertility patients had scrotal sonography examination. Fifty-seven percent showed abnormal sonogram; such as epididymitis, epididymo-orchitis, orchitis, varicocele, spermatocele, epididymal cyst and undescended testis. Among all lesions, infection was the commonest finding. There ...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000471634
更新日期:1989-01-01 00:00:00
abstract::Addition of docetaxel to androgen deprivation therapy (ADT) was recommended for patients with newly diagnosed metastatic hormone-sensitive prostate cancer (mHSPC), who are fit enough to receive docetaxel. Two recently published trials showed that the addition of abiraterone acetate plus prednisone to ADT has a clear s...
journal_title:European urology
pub_type: 社论
doi:10.1016/j.eururo.2017.09.029
更新日期:2018-03-01 00:00:00
abstract::A nearly symmetrical ureteral necrosis was observed in a child with dermatomyositis. The ureters were treated conventionally by resection, anastomosis and repeated catheterization with good results. ...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000473325
更新日期:1980-01-01 00:00:00
abstract:BACKGROUND:Information on autonomic neurapraxia in female urogenital surgery is scarce, and a model to study it is not available. OBJECTIVE:To develop a model to study the impact of autonomic neurapraxia on bladder function in female rats, as well as to assess the effects of corticosteroid therapy on the recovery of b...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2012.04.037
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Few observational studies have investigated the association between androgen deprivation therapy (ADT) and venous thromboembolism (VTE) in patients with prostate cancer (PCa). OBJECTIVE:To determine whether the use of different types of ADT in patients with PCa is associated with an increased incidence of V...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2015.06.022
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Macroscopic landmarks are lacking to identify the cavernosal nerves (CNs) during radical prostatectomy. The prostatic and capsular arteries run along the lateral border of the prostate and could help identify the location of the CNs during robot-assisted radical prostatectomy (RARP). OBJECTIVE:Describe the ...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2011.12.047
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:Primary culture and animal and cell-line models of prostate and bladder development have limitations in describing human biology, and novel strategies that describe the full spectrum of differentiation from foetal through to ageing tissue are required. Recent advances in biology demonstrate that direct repro...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2013.03.054
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVES:The aim of this prospective study was to compare the diagnostic accuracy of detrusor wall thickness (DWT), free uroflowmetry, postvoid residual urine, and prostate volume (index tests) with pressure-flow studies (reference standard) to detect bladder outlet obstruction (BOO) in men. METHODS:During a 2-yr pe...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2006.12.023
更新日期:2007-09-01 00:00:00
abstract::A 3-year-old boy with relapsing nephrosis presented with a left sided varicocele. Echographic studies demonstrated enlargement of the left kidney, and there was delayed excretion on renal scintigraphy suggesting the presence of renal vein thrombosis. The varicocele resolved with remission of his nephrosis. ...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000472498
更新日期:1985-01-01 00:00:00
abstract::Ninety-one patients with unstable detrusor and urge incontinence were treated with maximal electrical stimulation. There were 17 dropouts. From the remaining 74 patients 51 were subjectively cured or significantly improved, this effect lasted for more than 6 weeks in 40. Objectively a significant decrease in frequency...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000463887
更新日期:1990-01-01 00:00:00
abstract::The cellular immunocompetence was examined in 132 patients with transitional cell carcinoma of the bladder and 85 patients with carcinoma of the prostate with reference to the tumour stage and grade. In both groups a significant correlation between tumour stage and grade was found. These two parameters were also corre...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000472048
更新日期:1977-01-01 00:00:00
abstract:BACKGROUND:The role of cytoreductive nephrectomy in metastatic clear cell renal cell carcinoma (ccRCC) is controversial. OBJECTIVE:To determine the outcome of patients with metastatic ccRCC who receive sunitinib prior to planned nephrectomy. DESIGN, SETTING, AND PARTICIPANTS:The study combined the data from two prosp...
journal_title:European urology
pub_type: 杂志文章,meta分析
doi:10.1016/j.eururo.2011.05.028
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Radical perineal prostatectomy (RPP) has been revived with the advent of single-port (SP) robotic surgery. However, its interest and precise role need to be evaluated and better defined. OBJECTIVE:To describe in detail the technique of SP-RPP and compare initial perioperative outcomes with those of multipor...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2020.12.013
更新日期:2020-12-20 00:00:00
abstract:BACKGROUND:Patients with end-stage renal disease (ESRD) are at risk of developing renal tumours. OBJECTIVE:Compare clinical, pathologic, and outcome features of renal cell carcinomas (RCCs) in ESRD patients and in patients from the general population. DESIGN, SETTING, AND PARTICIPANTS:Twenty-four French university de...
journal_title:European urology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.eururo.2011.02.035
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:The prognostic impact of primary tumor location on outcomes for patients with upper-tract urothelial carcinoma (UTUC) is still contentious. OBJECTIVE:To test the association between tumor location and disease recurrence and cancer-specific survival (CSS) in patients treated with radical nephroureterectomy (...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2010.07.003
更新日期:2010-10-01 00:00:00
abstract::In 1976 a standardised hypertonic 'intracellular' perfusate (Euro-Collins solution) was recommended for renal preservation in all donor centres collaborating with the Eurotransplant Organisation. In order to investigate the effectiveness of this perfusate canine kidneys were initially flushed with Euro-Collins solutio...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000473336
更新日期:1980-01-01 00:00:00
abstract:OBJECTIVES:The repair of severe primary hypospadias represents a major surgical challenge. After initial enthusiasm for single-stage procedures, many paediatric urologists have turned to the alternative two-stage approach after experiencing disappointing results. A single surgeon's experience of the two-stage procedure...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2006.01.002
更新日期:2006-08-01 00:00:00
abstract::30 patients with neurogenic bladder dysfunction were treated with intermittent self-catheterization. Since the application of this method, urine loss has disappeared almost completely and the urinary infection rate has decreased. In some cases there was radiological improvement of the upper urinary tract. In all the o...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000473301
更新日期:1980-01-01 00:00:00
abstract::From February to September 1987, a prospective study was performed at two clinics to compare the Piezolith and the Dornier HM3+ lithotripters. Based on the same clinical indications for extracorporeal shock wave lithotripsy, 334 patients were treated with the Dornier HM3+ and 378 patients with the Piezolith. Whereas s...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000471518
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:The pathophysiology of interstitial cystitis (IC) is unknown. Deficits in urothelial cell layers and autoimmune mechanisms may play a role. OBJECTIVE:To examine whether immunization of mice with recombinant mouse uroplakin II (rmUPK2), a bladder-specific protein, would provoke an autoimmune response suffici...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2011.06.028
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVES:T1G3 superficial bladder cancer is considered to be at high risk for progression, and in some institutions early cystectomy is advocated. Other authors and personal experience suggest that conservative treatment, such as TURBT followed by intravesical prophylaxis, may be adequate in the majority of cases. Th...
journal_title:European urology
pub_type: 临床试验,杂志文章
doi:10.1159/000020171
更新日期:2000-04-01 00:00:00
abstract:OBJECTIVE:To study the local host response in patients with colonic and ileal neobladders, with or without bacteriuria. METHODS:Twenty-three patients with colonic neobladders and 19 with ileal neobladders were included. Eleven radical prostatectomy patients and seven healthy male volunteers were used as controls. Six ...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2006.02.012
更新日期:2006-11-01 00:00:00