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Effect of Momordica charantia fruit juice on streptozotocin-induced diabetes in rats.

Abstract：

:The oral hypoglycaemic activity of Momordica charantia fruit juice was investigated in rats with streptozotocin-induced diabetes. Oral administration of the juice (10 ml/kg for 30 days) did not show a significant effect, either acute or cumulative, on the ability to tolerate an external glucose load. The glycosylated haemoglobin concentrations were significantly elevated in both juice-treated and untreated diabetic rats and there was no significant difference between the two groups. Viable beta-cells capable of secreting insulin upon stimulation appear to be required for M. charantia to exert its oral hypoglycaemic activity.

journal_name

J Ethnopharmacol

journal_title

Journal of ethnopharmacology

authors

Karunanayake EH,Jeevathayaparan S,Tennekoon KH

doi

10.1016/0378-8741(90)90008-h

subject

Has Abstract

pub_date

1990-09-01 00:00:00

pages

199-204

issue

2

eissn

0378-8741

issn

1872-7573

pii

0378-8741(90)90008-H

journal_volume

30

pub_type

杂志文章

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