Ultrasound: medical imaging and beyond (an invited review).

abstract：:The ubiquitin-proteasome pathway (UPP) is the major non-lysosomal proteolytic system in the cytosol and nucleus of all eukaryotic cells. Bortezomib (also known as PS-341 and Velcade) is a proteasome inhibitor, a novel class of cancer therapies. Bortezomib blocks multi-ubiquitinated protein degradation by inhibiting 26...

journal_title：Current pharmaceutical biotechnology

authors： Roccaro AM,Hideshima T,Richardson PG,Russo D,Ribatti D,Vacca A,Dammacco F,Anderson KC

更新日期：2006-12-01 00:00:00

abstract：:Whole-cell bio-chips for functional sensing integrate living cells on miniaturized platforms made by micro-system-technologies (MST). The cells are integrated, deposited or immersed in a media which is in contact with the chip. The cells behavior is monitored via electrical, electrochemical or optical methods. In this...

journal_title：Current pharmaceutical biotechnology

authors： Shacham-Diamand Y,Belkin S,Rishpon J,Elad T,Melamed S,Biran A,Yagur-Kroll S,Almog R,Daniel R,Ben-Yoav H,Rabner A,Vernick S,Elman N,Popovtzer R

更新日期：2010-06-01 00:00:00

abstract：:The idea of cancer stem cell (CSC) has recently moved to the forefront of cancer research. There is still a lack of a widespread consensus on their description and definition. ,The increasing literature on CSCs has compelled researchers worldwide to rewrite the natural history of cancer including those cells as princi...

journal_title：Current pharmaceutical biotechnology

authors： Albini A,Cesana E,Noonan DM

更新日期：2011-02-01 00:00:00

abstract：:Lipid nanocapsules with their unique composition represent a promising biocompatible drug delivery platform in nanometer range with narrow size distribution. They are highly stable in comparison to other nano-vectors and were found to impart very desirable characteristics to the therapeutic molecule being delivered wi...

journal_title：Current pharmaceutical biotechnology

authors： Nasr M,Abdel-Hamid S

更新日期：2015-01-01 00:00:00

abstract：:Platelet-rich plasma (PRP) is widely used to promote tissue repair and accelerate osteogenesis, but there is no agreement about its mechanism of action. We characterized the modulatory effect of PRP on the in vitro osteoblast model SaOS-2, by using cell motility/chemoattraction and osteogenesis/mineralization assays, ...

journal_title：Current pharmaceutical biotechnology

authors： Martinotti S,Mazzucco L,Balbo V,Patrone M,Mozzati M,Ranzato E,Burlando B

更新日期：2014-01-01 00:00:00

abstract：:Wound healing is a complex process that consists of several phases that range from coagulation, inflammation, accumulation of radical substances, to proliferation, formation of fibrous tissues and collagen, contraction of wound with formation of granulation tissue and scar. Since antiquity, vegetable substances have b...

journal_title：Current pharmaceutical biotechnology

authors： Tejada S,Manayi A,Daglia M,Nabavi SF,Sureda A,Hajheydari Z,Gortzi O,Pazoki-Toroudi H,Nabavi SM

更新日期：2016-07-21 00:00:00

abstract：BACKGROUND:Nanotechnology involves the synthesis of materials that are in nanometre sizes (1 to 100 nm). Nanotechnology has appeared as a new area of fundamental science and is getting worldwide consideration due to its extensive applications. They have exceptional physicochemical properties due to their unique size, s...

journal_title：Current pharmaceutical biotechnology

authors： Roy A

更新日期：2020-10-27 00:00:00

abstract：:Tumor immune surveillance paradigm presumes that most pre-malignant cells or early malignant lesions can be eliminated (or at least controlled) by cells of the immune system. A critical feature that distinguishes advanced tumors from early neoplastic lesions is their capability to evade immune control. As a consequenc...

journal_title：Current pharmaceutical biotechnology

authors： Klener P Jr,Otáhal P,Lateckova L,Klener P

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:To date, an increasing number of pet owners, especially in the USA, are using cannabis-derived products containing generally delta 9-tetrahydrocannabinol (THC) and cannabidiol (CBD) to help their animals' health. Unfortunately, studies on the clinical use of cannabinoids in veterinary medicine are still limi...

journal_title：Current pharmaceutical biotechnology

authors： Rotolo MC,Graziano S,Pellegrini M,Corlazzoli D,Antinori L,Porcarelli L,Pichini S

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Vulvar Lichen Sclerosus (VLS) is a chronic inflammatory disease with a huge impact on a person's quality of life. A correct therapy is required for relieving symptoms, reversing signs and preventing further anatomical changes. OBJECTIVE:The main objective of the present paper is to provide suggestions for t...

journal_title：Current pharmaceutical biotechnology

authors： Borghi A,Corazza M

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Although the stability of proteins is of significance to maintain protein function for therapeutical applications, this remains a challenge. Herein, a general method of preserving protein stability and function was developed using gelatin films. METHODS:Enzymes immobilized onto films composed of gelatin and...

journal_title：Current pharmaceutical biotechnology

authors： Zhang L,Shen Y,Lu W,Guo L,Xiang M,Zhang D

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:Frequent administrations for DPPIV-resistant GLP-1 analogs are necessary to maintain the blood concentrations due to the short half-life of less than 5 minutes. However, most delivery systems that possess the ability of sustainable release of GLP-1 have drawbacks such as low yield, high cost and undesirable s...

journal_title：Current pharmaceutical biotechnology

authors： Fan L,Fan Y,Fan H,Huang K

更新日期：2020-01-01 00:00:00

abstract：:Hyaluronan (HA) is a highly biocompatible biopolymer that is widely used for a variety of therapeutic purposes including surgical preparations, adhesion prevention, viscosupplementation and drug and cytokine delivery. Delivery can be accomplished effectively when HA-based carriers are synthesized in the form of hydrog...

journal_title：Current pharmaceutical biotechnology

authors： Peattie RA

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Carbon nanotubes (CNTs) have been considered highly successful and proficient in terms of their mechanical, thermal and electrical functionalization and biocompatibility. In regards to their significant extent in bone regeneration, it has been determined that CNTs hold the capability to endure clinical appli...

journal_title：Current pharmaceutical biotechnology

authors： Ilbasmis-Tamer S,Ciftci H,Turk M,Degim T,Tamer U

更新日期：2017-01-01 00:00:00

abstract：:There is a growing trend of herbal medicines in India as well as other parts of the world. The use of herbal medicines alone or alongside prescription drugs for disease management is quite common now. We hereby carry out a review of dominant species of Selinum mainly S. vaginatum C.B. Clarke and S. wallichianum (DC.) ...

journal_title：Current pharmaceutical biotechnology

authors： Srivastava RP,Dixit P,Singh L,Verma PC,Saxena G

更新日期：2018-01-01 00:00:00

abstract：:As sessile and filter-feeding metazoans, marine sponges represent an ecologically important and highly diverse component of marine benthic communities throughout the world. It has been suggested that marine sponges are hosts to many microorganisms which can constitute up to 40-60% of its biomass. Recently, sponges hav...

journal_title：Current pharmaceutical biotechnology

authors： Santos-Gandelman JF,Giambiagi-deMarval M,Oelemann WM,Laport MS

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:Advanced gastrointestinal stromal tumours (GISTs) are treated with tyrosine kinase inhibitors, which also have antiangiogenic properties. Dual-energy CT (DECT) allows to acquire semi-quantitative iodine images which might correlate with blood pool and tumor vascularity. In this feasibility-study, we correlated ...

journal_title：Current pharmaceutical biotechnology

authors： Schramm N,Schlemmer M,Englhart E,Hittinger M,Becker C,Reiser M,Berger F

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Connexin (Cx) proteins are the building blocks of gap junctions. Among these, Cx37 and Cx40 are expressed on vascular system and reported to have cardioprotective role. Linking polymorphisms in genes coding for Cx and coronary artery disease (CAD) risk showed conflicting results in different populations. Non...

journal_title：Current pharmaceutical biotechnology

authors： El Tahry FA,Hashad IM,Abdel Rahman MF,Gad MZ

更新日期：2017-11-10 00:00:00

abstract：OBJECTIVE:The goals of this study were to observe how luteolin protects endothelial cells (ECs) from injury stimulated by Angiotensin II (Ang II), investigate the role of vascular endothelial dysfunction in vascular smooth muscle cell proliferation and migration in vitro and investigate its primary mechanism of action....

journal_title：Current pharmaceutical biotechnology

authors： Ding H,Li D,Zhang Y,Zhang T,Zhu H,Xu T,Luo Y,Wang C

更新日期：2014-01-01 00:00:00

abstract：:Ribotoxins constitute a family of toxic extracellular fungal RNases that exert a highly specific activity on a conserved region of the larger molecule of rRNA, known as the sarcin-ricin loop. This cleavage of a single phosphodiester bond inactivates the ribosome and leads to protein synthesis inhibition and cell death...

journal_title：Current pharmaceutical biotechnology

authors： Carreras-Sangrà N,Alvarez-García E,Herrero-Galán E,Tomé J,Lacadena J,Alegre-Cebollada J,Oñaderra M,Gavilanes JG,Martínez-Del-Pozo A

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Terminalia arjuna (TA) has been reported and explored traditionally for its cardiotonic properties while the mechanism of antihypertensive effect of TA has not been clearly reported. METHOD:The oxidative stress is a major cause for hypertension, hence different extracts of TA having variable marker yield we...

journal_title：Current pharmaceutical biotechnology

authors： Khatkar S,Nanda A,Ansari SH

更新日期：2019-01-01 00:00:00

abstract：:As an important nano-material, nano-copper oxide particles (CuO-ENPs) harbor a vast range of characteristics, including electronic correlation effect, thermal stability, catalytic activity, sterilization and other properties. At present, the mechanism of ecotoxicological effects of CuO-ENPs is not yet clear, and has b...

journal_title：Current pharmaceutical biotechnology

authors： Li T,Hu H,Yang C,Zhang B,Ma L

更新日期：2020-12-28 00:00:00

abstract：:Fc-based therapeutics including therapeutic full-size monoclonal antibodies (mAbs) and Fcfusion proteins represent fastest-growing market in biopharmaceutical industrial. However, one major challenge during development of Fc-based therapeutics is how to maintain their efficacy in clinic use. Many factors may lead to f...

journal_title：Current pharmaceutical biotechnology

authors： Chen X,Zeng F,Huang T,Cheng L,Liu H,Gong R

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Common variable immunodeficiency (CVID) encompasses a heterogeneous group of primary antibody deficiency disorders characterized by recurrent infections, autoimmunity and malignancies. Gastrointestinal manifestations are frequently associated with CVID. OBJECTIVE:In this cross-sectional study, we evaluated ...

journal_title：Current pharmaceutical biotechnology

authors： Varricchi G,Pecoraro A,Crescenzi L,Marone G,Travaglino A,D'Armiento FP,Genovese A,Spadaro G

更新日期：2018-01-01 00:00:00

abstract：:In this review, the compartments of the vasculature will be discussed with respect to their potential contribution to the build-up of a differentiated and functionally meaningful vessel system. Chronic ischemia of muscle tissue results in microvessel rarification, which represents a potential therapeutic target, given...

journal_title：Current pharmaceutical biotechnology

authors： Kupatt C

更新日期：2007-02-01 00:00:00

abstract：:Calendula officinalis of family Asteraceae, also known as marigold, has been widely used from time immemorial in Indian and Arabic cultures as an anti-inflammatory agent to treat minor skin wound and infections, burns, bee stings, sunburn and cancer. At a relatively high dose, calendula can lower blood pressure and ch...

journal_title：Current pharmaceutical biotechnology

authors： Ray D,Mukherjee S,Falchi M,Bertelli A,Das DK

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Bacteriophages are viruses, which are obligate parasites of specific bacteria for the completion of their lifecycle. Bacteriophages could be the possible alternative to antibioticresistant bacterial diseases. With this objective, extensive research in different fields is published which are discussed in this...

journal_title：Current pharmaceutical biotechnology

authors： Adhikari N,Acharya KP

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Up to 25% of diabetic patients will develop a diabetic foot ulcer. Chronic wounds such as diabetic foot ulcers often fail to heal with conventional therapies. In recent years, it has been identified that chronic wounds are usually associated with elevated level of matrix metalloproteinases (MMPs). Doxycyclin...

journal_title：Current pharmaceutical biotechnology

authors： Xu DH,Zhu Z,Fang Y

更新日期：2017-01-01 00:00:00

abstract：: ...

journal_title：Current pharmaceutical biotechnology

authors： Blum K,Baron D

更新日期：2019-01-01 00:00:00

abstract：:The accidental or intentional release of plutonium or americium can cause acute and long term adverse health effects if they enter the human body by ingestion, inhalation, or injection. These effects can be prevented by rapid removal of these radionuclides by chelators such as calcium or zinc diethylenetriaminepentaac...

journal_title：Current pharmaceutical biotechnology

authors： Kazzi ZN,Heyl A,Ruprecht J

更新日期：2012-08-01 00:00:00