Effectiveness of Bacteriophage Therapy in Field Conditions and Possible Future Applications.

abstract：BACKGROUND:The present limitations related to the ocular administration of antifungal drugs for the treatment of fungal keratitis include poor ocular bioavailability, limited retention time, and low ocular tissues penetration. METHODS:This study aimed to prepare a novel ophthalmic voriconazole-loaded nanosuspension ba...

journal_title：Current pharmaceutical biotechnology

authors： Qin T,Dai Z,Xu X,Zhang Z,You X,Sun H,Liu M,Zhu H

更新日期：2020-08-20 00:00:00

abstract：BACKGROUND:`Herbal mixtures` containing synthetic cannabinoid receptor agonists (SCRAs) are promoted as legal alternative to marihuana and are easily available via the Internet. Keeping analytical methods for the detection of these SCRAs up-to-date is a continuous challenge for clinicians and toxicologists due to the h...

journal_title：Current pharmaceutical biotechnology

authors： Hutter M,Broecker S,Kneisel S,Franz F,Brandt SD,Auwarter V

更新日期：2018-01-01 00:00:00

abstract：:Raman spectroscopy has long been used as a powerful tool for chemical composition analyses. Raman scattering light measurement has the advantage of being able to examine biomolecules in a nondestructive and non-labeling manner. However, molecular imaging of cells and tissues by using Raman microscopy had been hampered...

journal_title：Current pharmaceutical biotechnology

authors： Harada Y,Takamatsu T

更新日期：2013-01-01 00:00:00

abstract：:Spirulina, a filamentous cyanobacterium, possesses diverse biological activities and nutritional significance due to high concentration of natural nutrients, having bio-modulatory and immuno-modulatory functions. Different Spirulina preparations influence immune system viz. increase phagocytic activity of macrophages,...

journal_title：Current pharmaceutical biotechnology

authors： Khan Z,Bhadouria P,Bisen PS

更新日期：2005-10-01 00:00:00

abstract：: ...

journal_title：Current pharmaceutical biotechnology

authors： Giaginis C

更新日期：2018-01-01 00:00:00

abstract：:Lactobacilli are common microorganisms in diverse vegetables and meat products and several of these are also indigenous inhabitants in the gastro-intestinal (GI) tract of humans and animals where they are believed to have health promoting effects on the host. One of the highly appreciated probiotic effects is their ab...

journal_title：Current pharmaceutical biotechnology

authors： Diep DB,Mathiesen G,Eijsink VG,Nes IF

更新日期：2009-01-01 00:00:00

abstract：:This mini-review describes how single-molecule sensitive fluorescence resonance energy transfer (FRET) and photoinduced electron transfer (PET) reactions can be successfully applied to monitor conformational dynamics in biopolymers. Single-pair FRET experiments are ideally suited to study conformational dynamics occur...

journal_title：Current pharmaceutical biotechnology

authors： Neuweiler H,Sauer M

更新日期：2004-06-01 00:00:00

abstract：:The purpose of this review article is to describe the history of photodynamic therapy (PDT), its current medical applications, the mechanism of action, contraindications of the method, and different types of photosensitizers used. The second part of the article deals with applications for gastrointestinal diseases. Th...

journal_title：Current pharmaceutical biotechnology

authors： Wiedmann MW,Caca K

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND & OBJECTIVE:Nutritional culturomics (NCs) is a specific focus area of culturomics epistemology developing digital humanities and computational linguistics approaches to search for macro-patterns of public interest in food, nutrition and diet choice as a major component of cultural evolution. Cultural evoluti...

journal_title：Current pharmaceutical biotechnology

authors： Troumbis AY,Hatziantoniou M,Vasios GK

更新日期：2019-01-01 00:00:00

abstract：:X-ray is a non-thermal technology that has shown good efficacy in reducing pathogenic and spoilage bacteria, viruses and parasites. X-ray hygiene technology resulted in a high microbial loss in numerous food products, such as dairy products, ready-to-eat shrimp, oysters, fresh products, strawberries, shredded iceberg ...

journal_title：Current pharmaceutical biotechnology

authors： Zehi ZB,Afshari A,Noori SMA,Jannat B,Hashemi M

更新日期：2020-01-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs), a form of adult stem cells, are known to have a self-renewing property and the potential to specialize into a multitude of cells and tissues such as adipocytes, cartilage cells, and fibroblasts. MSCs can migrate and home to the desired target zone where inflammation is present. The uniqu...

journal_title：Current pharmaceutical biotechnology

authors： Saeedi M,Nezhad MS,Mehranfar F,Golpour M,Esakandari MA,Rashmeie Z,Ghorbani M,Nasimi F,Hoseinian SN

更新日期：2020-09-07 00:00:00

abstract：:Foods and nutrients play a vital role in normal functioning of the body. They are helpful in maintaining the health of the individual and in reducing the risk of various diseases. Worldwide acceptance of this fact formed a recognition link between "nutrition" and "health" and the concept of "nutraceuticals" was evolve...

journal_title：Current pharmaceutical biotechnology

authors： Ramaa CS,Shirode AR,Mundada AS,Kadam VJ

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Semaphorin 3B (SEMA3B) is characterized as a strong suppressing factor of the proliferation of cancerous cells and also by its anti-angiogenic effect. However, the knowledge on the changes in the expression profile of SEMA3B under the influence of cisplatin in endometrial cancer remains fragmented. The aim o...

journal_title：Current pharmaceutical biotechnology

authors： Peszek W,Kras P,Grabarek BO,Boroń D,Oplawski M

更新日期：2020-01-01 00:00:00

abstract：:The accidental or intentional release of plutonium or americium can cause acute and long term adverse health effects if they enter the human body by ingestion, inhalation, or injection. These effects can be prevented by rapid removal of these radionuclides by chelators such as calcium or zinc diethylenetriaminepentaac...

journal_title：Current pharmaceutical biotechnology

authors： Kazzi ZN,Heyl A,Ruprecht J

更新日期：2012-08-01 00:00:00

abstract：:Objective: CME-1 is a polysaccharide purified from the mycelia of medicinal mushroom Cordyceps sinensis, its molecular weight was determined to be 27.6 kDa by using nuclear magnetic resonance and gas chromatography-mass spectrometry. The initiation of arterial thromboses is relevant to various cardiovascular diseases ...

journal_title：Current pharmaceutical biotechnology

authors： Chang YI,Hsu WH,Lu WJ,Jayakumar T,Liao JC,Lin MJ,Wang SH,Geraldine P,Lin KH,Sheu JR

更新日期：2015-03-03 00:00:00

abstract：AIMS:Globally Scientists are working to find more efficient antimicrobial drugs to treat microbial infections and kill drug-resistant bacteria. BACKGROUND:Despite the availability of numerous antimicrobial drugs bacterial infections still poses a serious threat to global health. Due to a constant decline in the effect...

journal_title：Current pharmaceutical biotechnology

authors： Khan K,Qureshi MA,Azam A,Moinuddin,Musarrat J,Javed S

更新日期：2021-01-18 00:00:00

abstract：BACKGROUND:Cancer is the leading cause of death worldwide and the current mode of cancer treatment causes side effects on normal cells and are still the key challenges in its' treatment. However, natural products or active compounds of medicinal plants have shown to be safe, affordable, and effective in diseases cure. ...

journal_title：Current pharmaceutical biotechnology

authors： Almatroodi SA,Almatroudi A,Alsahli MA,Khan AA,Rahmani AH

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Bacterial lipases especially Pseudomonas lipases are extensively used for different biotechnological applications. OBJECTIVES:With the better understanding and progressive needs for improving its activity in accordance with the growing market demand, we aimed in this study to improve the recombinant product...

journal_title：Current pharmaceutical biotechnology

authors： El-Aziz AMA,Shaker MA,Shaaban MI

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:The work was performed to investigate the feasibility of preparing ocular inserts loaded with Poly-ε-Caprolactone (PCL) nanoparticles as a sustained ocular delivery system. METHODS:First, Atorvastatin Calcium-Poly-ε-Caprolactone (ATC-PCL) nanoparticles were prepared and characterized. Then, the optimized nanop...

journal_title：Current pharmaceutical biotechnology

authors： Girgis GNS

更新日期：2020-01-01 00:00:00

abstract：:In the past decade, a range of dental products have appeared which make advertising claims around preventing mineral loss or repairing mineral loss. This review examines the requirements for effective protection of tooth structure, and the evidence around technologies now available for preventing tooth structure loss ...

journal_title：Current pharmaceutical biotechnology

authors： Walsh LJ

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Burn is still an important global public health challenge. Wound colonization of antibiotic resistant bacteria such as Acinetobacter baumannii can lead to high morbidity and mortality in burn patients. The aim of this study was to evaluate the inhibitory effect of tazobactam on efflux pump, which can cause a...

journal_title：Current pharmaceutical biotechnology

authors： Azimi L,Tahbaz SV,Alaghehbandan R,Alinejad F,Lari AR

更新日期：2020-01-01 00:00:00

abstract：:Over the last 50 years, evidence for central involvement of glutamatergic neurotransmission in the pathophysiology of schizophrenia has accumulated. Recent advances in neuroimaging technology now allow several components of glutamatergic neurotransmission to be assessed in the living human brain. Positron emission tom...

journal_title：Current pharmaceutical biotechnology

authors： Egerton A,Stone JM

更新日期：2012-06-01 00:00:00

abstract：:The recent developement of platelet concentrate for surgical use is an evolution of the fibrin glue technologies used since many years. The initial concept of these autologous preparations was to concentrate platelets and their growth factors in a plasma solution, and to activate it into a fibrin gel on a surgical sit...

journal_title：Current pharmaceutical biotechnology

authors： Bielecki T,Dohan Ehrenfest DM

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Although Semaphorin 3A (Sema3A)/ Neuropilin-1(NRP1)/Plexin A1 is one of the important targets in bone metabolism, few studies are done on this target in the glucocorticoids-induced osteoporosis. Luteolin is a chemical component of Honeysuckle and it has various bioactivities. The effect and study of Luteolin...

journal_title：Current pharmaceutical biotechnology

authors： Zheng L

更新日期：2020-12-16 00:00:00

abstract：:Gene targeting can be loosely defined as a process through which a specific chromosomal sequence is recognized and bound by a reagent designed for the purpose. The endpoint may be modulation of events at the target, such as transcription, or a permanent change in sequence at the site. A facile strategy for mammalian c...

journal_title：Current pharmaceutical biotechnology

authors： Seidman MM

更新日期：2004-10-01 00:00:00

abstract：:More than 80% of all cancers are caused by solid malignancies. More than 90% of these tumours are of epithelial origin. The main principles in tumour treatment are surgery, radiotherapy, chemotherapy or combinations of these. Complete surgical removal of the tumour is the most effective therapy for solid malignancies....

journal_title：Current pharmaceutical biotechnology

authors： Mauerer R,Gruber R

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Powdery drugs such as cocaine and heroin are frequently adulterated or diluted predominantly to obtain more doses and to increase the drug dealer's profits, but also to enhance, to modify or to oppose drug effects. The aim of this report is to provide an overview of the recent scientific literature on medici...

journal_title：Current pharmaceutical biotechnology

authors： Solimini R,Rotolo MC,Pellegrini M,Minutillo A,Pacifici R,Busardò FP,Zaami S

更新日期：2017-01-01 00:00:00

abstract：:Polyphenols are a widely distributed group of natural products found in fruits, vegetables, nuts, seeds, stems and flowers. Such compounds, especially dietary flavonoids and tannins, have been shown to exert antioxidant, antiinflammatory, anti-cancer and antibacterial effects and may have beneficial effects on human h...

journal_title：Current pharmaceutical biotechnology

authors： Coppo E,Marchese A

更新日期：2014-01-01 00:00:00

abstract：:Tumor immune surveillance paradigm presumes that most pre-malignant cells or early malignant lesions can be eliminated (or at least controlled) by cells of the immune system. A critical feature that distinguishes advanced tumors from early neoplastic lesions is their capability to evade immune control. As a consequenc...

journal_title：Current pharmaceutical biotechnology

authors： Klener P Jr,Otáhal P,Lateckova L,Klener P

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Citronella Oil (CO) was used by the Indian army as mosquito repellant to repel mosquitoes at the beginning of the 20th century and later in 1948, it was registered in the USA for commercial purposes. Due to its ecofriendly nature, CO possesses immense potential as a mosquito repellent. METHODS:Citronella oi...

journal_title：Current pharmaceutical biotechnology

authors： Sharma R,Kumar N,Singh SP,Kumar S,Rao R

更新日期：2020-01-01 00:00:00