Abstract：
:Neurofibrillary pathology in Alzheimer's disease consists of paired helical filaments comprising tau protein. This pathology is correlated with dementia, but can appear in the first two decades of life. Extracellular amyloid β-protein arises through proteolytic processing of a transmembrane precursor, which involves the action of several enzymes. Mutations in the genes for the precursor and presenilin proteins accelerate the deposition of Aβ. Tau mutations cause other tauopathies in the absence of amyloid deposition, indicating that amyloid deposition is not a prerequisite for dementia. An improved understanding of Alzheimer's disease awaits to be obtained by molecular imaging of these pathologies.
journal_name
Neuroimaging Clin N Amjournal_title
Neuroimaging clinics of North Americaauthors
Harrington CRdoi
10.1016/j.nic.2011.11.003subject
Has Abstractpub_date
2012-02-01 00:00:00pages
11-22, viiissue
1eissn
1052-5149issn
1557-9867pii
S1052-5149(11)00173-0journal_volume
22pub_type
杂志文章,评审abstract：:Dynamic functional connectivity adds another dimension to resting-state functional MR imaging analysis. In recent years, dynamic functional connectivity has been increasingly used in resting-state functional MR imaging, and several studies have demonstrated that dynamic functional connectivity patterns correlate with ...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nic.2020.09.004
更新日期：2021-02-01 00:00:00
abstract：:Vertebral augmentation techniques use image guidance for the percutaneous placement of spinal implants that stabilize a painful osteoporotic or pathologic vertebral compression fracture. The initial implant, acrylic bone cement, was injected through a bone needle into the vertebral body, a procedure referred to as ver...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nic.2010.02.001
更新日期：2010-05-01 00:00:00
abstract：:Oral cavity cancer comprises nearly 30% of all malignant tumors of the head and neck. After a definitive diagnosis has been made, imaging is essential for staging the primary tumor by evaluating submucosal spread and invasion of adjacent structures, and to identify nodal or distant metastasis. Oral cavity anatomy is o...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nic.2012.08.004
更新日期：2013-02-01 00:00:00
abstract：:Arterial supply of hippocampal formation in humans has been studied by many investigators in the past. More recently, investigation of correlation of complex partial seizure with mesial temporal sclerosis has brought a resurgence of interest in studying the hippocampus. This article discusses arterial architecture of ...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章
doi：
更新日期：1997-02-01 00:00:00
abstract：:Lymphomas are subdivided into HL and NHL and are more specifically classified into subtypes of HL or NHL according to the WHO classification. HLs involve the lymph nodes predominantly and only approximately 5% arise in extranodal sites, whereas 30% of NHLs present in extranodal sites. Imaging studies, including CT and...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s1052-5149(03)00039-x
更新日期：2003-08-01 00:00:00
abstract：:Magnetoencephalography (MEG) is a noninvasive neuroimaging technique that measures the electromagnetic fields generated by the human brain. This article highlights the benefits that pediatric MEG has to offer to clinical practice and pediatric research, particularly for infants and young children; reviews the existing...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nic.2020.02.002
更新日期：2020-05-01 00:00:00
abstract：:Spontaneous intracranial hemorrhage is a commonly encountered neurologic emergency. Imaging plays important roles in both guiding the emergent stabilization of patients with ICH and in elucidating the etiology of the hemorrhage to prevent rebleeding. A thorough understanding of the factors that have an impact on immed...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nic.2018.03.003
更新日期：2018-08-01 00:00:00
abstract：:Surgical approaches to the skull base have seen significant evolution. The most practical approaches now use the concept of comprehensive integration of all phases of cranial base surgery, from modular disassembly of the craniofacial skeleton and tumor resection to a functional and aesthetic reconstruction. The improv...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章
doi：
更新日期：1994-08-01 00:00:00
abstract：:Spinal vascular malformations (AVMs) are rare but important causes of treatable myelopathies. Recent advances in the interventional neuroradiology and neurosurgical techniques have improved the delineation and classification of these heterogeneous lesions. Because MR imaging usually is the first screening test for pat...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：2001-02-01 00:00:00
abstract：:We discuss the arterial supply of the cranial nerves from their exit out of the brain stem to their exit from the skull base. Four distinct groups can be differentiated from an embryologic and phylogenetic standpoint. Understanding the arterial supply to the cranial nerves and the potential anastomoses is paramount in...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nic.2007.12.010
更新日期：2008-05-01 00:00:00
abstract：:For over 20 years, conventional MR imaging has been used for assessing brain tumors. However, conventional MR imaging tends to underestimate the extent of the tumor, perhaps leading to suboptimal treatment. New MR imaging tools have been widely used to determine the grade, heterogeneity, and extent of brain tumors. Di...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章
doi：10.1016/j.nic.2011.01.010
更新日期：2011-02-01 00:00:00
abstract：:Assessment of the oxygenation status of brain tumors has been studied increasingly with imaging techniques in light of recent advances in oncology. Tumor oxygen tension is a critical factor influencing the effectiveness of radiation and chemotherapy and malignant progression. Hypoxic tumors are resistant to treatment,...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s1052-5149(02)00029-1
更新日期：2002-11-01 00:00:00
abstract：:Resting-state functional connectivity is the synchronization of brain regions with each another. Alterations are suggestive of neurologic or psychological disorders. This article discusses methods and approaches used to describe resting-state brain connectivity and the results in neurotypical and diseased brains. ...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nic.2017.06.001
更新日期：2017-11-01 00:00:00
abstract：:Knowledge of relevant anatomy and underlying mechanisms of traumatic injury is essential for understanding the radiologic findings in craniofacial trauma and their clinical importance. Craniofacial anatomy is diverse, and as a result of this anatomic diversity, physicians from numerous different specialties scrutinize...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nic.2014.03.007
更新日期：2014-08-01 00:00:00
abstract：:Cryotherapy of the brain is an old and well-established technique of functional and resective neurosurgery. With the use of modern imaging techniques such as MR imaging, which is ideally suited for diagnosis, planning, and monitoring of an ablation procedure, cryotherapy can become a modern alternative to other ablati...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：2001-11-01 00:00:00
abstract：:Tumors of the head and neck are primary sites for radiation treatment. In combination with surgery, the role of radiation is further expanded; however, localization of the primary tumor and its metastases, actual or potential, and the relationship to critical structures are quintessential to the application of radiati...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1996-05-01 00:00:00
abstract：:Previously, CT was considered insensitive in the evaluation of the acute ischemic stroke patient; however, more recently detection of early CT findings has proved to be of prognostic value in the evaluation of these patients. The use of CT coupled with early acute phase therapy of stroke such as thrombolytic therapy h...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1998-08-01 00:00:00
abstract：:Diffusion-weighted imaging of the musculoskeletal system including the spine is a new MR imaging method. Several studies have shown significantly different diffusivities for various pathologic conditions such as edema and tumor. The specificity of diagnosis may be increased and therapeutic effects may be monitored. Di...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章
doi：10.1016/s1052-5149(03)00074-1
更新日期：2002-02-01 00:00:00
abstract：:Because of its superior depiction of bone detail, CT is a useful tool in the characterization of CF deformities and presurgical planning. Modern CT scanners and workstations provide 2D techniques such as multiplanar reformats and 3D techniques, such as MIP and volume renderings, which may be used effectively in the di...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s1052-5149(03)00061-3
更新日期：2003-08-01 00:00:00
abstract：:Computed tomography is often the first-line diagnostic imaging modality in the evaluation of patients with neurologic emergencies. A patient-centered approach to radiation dose management in emergent neuroimaging thus revolves around the appropriate use of computed tomography, including clinical decision support for o...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nic.2018.03.010
更新日期：2018-08-01 00:00:00
abstract：:Diskography has become a vital study in the evaluation of spinal pain, particularly in patients who are considered candidates for possible surgical intervention. It has been the author's experience that when diskography is performed with appropriate clinical indication by skilled and experienced practitioners who are ...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：2000-08-01 00:00:00
abstract：:High-flow AVFs are a challenging problem in the pediatric age group. Venous occlusive changes develop as part of the dynamic response to these fistulas. The development of adequate venous collateral flow circumvents the destructive sequelae of longstanding venous hypertension. Without adequate collaterals, venous hype...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s1052-5149(02)00093-x
更新日期：2003-02-01 00:00:00
abstract：:Evaluation of imaging studies of the cerebellum in inherited neurodegenerative disorders is aided by attention to neuroimaging patterns based on anatomic determinants, including biometric analysis, hyperintense signal of structures, including the cerebellar cortex, white matter, dentate nuclei, brainstem tracts, and n...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nic.2016.03.007
更新日期：2016-08-01 00:00:00
abstract：:Imaging of the postoperative spine is common, although it remains a difficult task for radiologists. This article presents an overview of common surgical approaches and spinal hardware, and specific complications that may be associated with each procedure. In addition, expected postoperative changes and complications ...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nic.2014.01.002
更新日期：2014-05-01 00:00:00
abstract：:Acute disseminated encephalomyelitis (ADEM) is a monophasic demyelinating disease of the central nervous system typically affecting the gray and the white matter of the brain and spinal cord in multiple locations. In the acute stages, ADEM is characterized histologically by perivenous edema, demyelination, and infiltr...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nic.2007.12.007
更新日期：2008-02-01 00:00:00
abstract：:Classical descriptions of the temporal bone are based on its five embryologically distinct osseous components: the petrous, tympanic, mastoid, squamous, and styloid portions. ...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章
doi：10.1016/j.nic.2004.07.008
更新日期：2004-11-01 00:00:00
abstract：:This article discusses the normal anatomy of the posterior fossa structures followed by a discussion of the characteristic neuroimaging features of a variety of cerebellar and brainstem malformations. In this context, the authors classify posterior fossa malformations based on the neuroimaging pattern into (1) predomi...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nic.2019.03.008
更新日期：2019-08-01 00:00:00
abstract：:Viral infections of the brain and spinal cord cause significant morbidity and mortality in patients afflicted with AIDS. Debate continues over the specific mechanisms and pathways of how HIV-1 manifests itself in the brain and spinal cord. Attempts to predict which seropositive patients develop neurocognitive deficits...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1997-05-01 00:00:00
abstract：:Conventional neuroimaging is still the mainstay in the assessment of the acute, follow-up, and chronic settings of concussion and mild traumatic brain injury (mTBI). Computed tomography (CT) is preferred for the initial assessment of acute mTBI, repeat evaluation in acute mTBI with neurologic deterioration, and cautio...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nic.2017.09.006
更新日期：2018-02-01 00:00:00
abstract：:Interpreting CT or MR imaging examinations performed on patients with a history of middle ear, mastoid, or neurotologic surgery can be challenging. This is greatly simplified by knowing the surgical procedures used and the expected postoperative appearance. These are reviewed and illustrated in this article. Knowing t...
journal_title：Neuroimaging clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nic.2009.06.005
更新日期：2009-08-01 00:00:00
