Abstract：
:This manuscript summarizes some of our earlier work on the microbiology of autism subjects' stool specimens, as compared with stools from control subjects. Our most recent data indicating that Desulfovibrio may play an important role in regressive autism is also presented. In addition, we present information on antimicrobial susceptibility patterns of Desulfovibrio using the CLSI agar dilution susceptibility technique. In addition, we summarize data from our earlier studies showing the impact of various antimicrobial agents on the indigenous bowel flora. This shows that penicillins and cephalosporins, as well as clindamycin, have a major impact on the normal bowel flora and therefore might well predispose subjects to overgrowth of such organisms as Clostridium difficile, and of particular importance for autism, to Desulfovibrio.
journal_name
Anaerobejournal_title
Anaerobeauthors
Finegold SM,Downes J,Summanen PHdoi
10.1016/j.anaerobe.2011.12.018subject
Has Abstractpub_date
2012-04-01 00:00:00pages
260-2issue
2eissn
1075-9964issn
1095-8274pii
S1075-9964(11)00242-3journal_volume
18pub_type
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