Abstract：
BACKGROUND:Ovarian Brenner tumors are rare epithelial tumors that account for 1%-2% of all ovarian neoplasms. They can be subdivided into benign, borderline or proliferative, and malignant neoplasms. In the vast majority of cases, these lesions are benign. Tumors of borderline malignancy are less frequent and only about 1% of Brenner tumors are malignant. We present two cases of Brenner tumors with borderline malignancy which were treated in our Department together with a review of the literature. CASES:A 50-year-old, gravida 1, para 1, patient was admitted for abnormal vaginal bleeding. Clinical examination, abdominal ultrasound (US), and computed tomography (CT) revealed a cystic multilobulated tumor of the right ovary with solid elements measuring 20 x 19 x 15 cm in diameter. In the other case a 70-year-old, gravida 2, para 2, patient presented with severe urinary difficulties. Palpation revealed a mobile abdominopelvic tumor 10 x 15 in diameter. US and CT exhibited a cystic tumor with multiple solid elements and calcifications of the left ovary. Both patients underwent exploratory laparotomy. Total abdominal hysterectomy with bilateral salpingo-oophorectomy and total omentectomy were performed in both cases, while pelvic lymphadenectomy was decided only in the second case. Histologically, in both cases the diagnosis confirmed borderline Brenner tumor. CONCLUSION:Although Brenner tumors are rare and the majority of them are benign, the correct histological diagnosis at frozen section with identification of the small proportion of malignant tumors, allows the extent of the operation to be adapted if needed.
journal_name
Eur J Gynaecol Oncoljournal_title
European journal of gynaecological oncologyauthors
Arnogiannaki N,Grigoriadis C,Zygouris D,Terzakis E,Sebastiadou M,Tserkezoglou Asubject
Has Abstractpub_date
2011-01-01 00:00:00pages
576-8issue
5eissn
0392-2936issn
2709-0086journal_volume
32pub_type
杂志文章,评审abstract：:Cervical cancer is the most common cancer among women in South India. More than 70% of the cases present in stage IIB and IIIB and of these more than 50% fail conventional treatment. The purpose of the present study was to determine the prognostic significance of Bcl-2 and p53 expression in squamous cell carcinomas of...
journal_title：European journal of gynaecological oncology
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journal_title：European journal of gynaecological oncology
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abstract：PURPOSE:To determine the impact of clinical variables and adjuvant therapy on survival in patients with Stage IVB endometrial cancer (EC) confined to abdomen. METHODS AND METHODS:A total of 65 patients were included. Curative chemotherapy was defined as using only chemotherapy (platin based) or sandwich therapy. Patie...
journal_title：European journal of gynaecological oncology
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journal_title：European journal of gynaecological oncology
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更新日期：1990-01-01 00:00:00
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journal_title：European journal of gynaecological oncology
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journal_title：European journal of gynaecological oncology
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journal_title：European journal of gynaecological oncology
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journal_title：European journal of gynaecological oncology
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更新日期：1990-01-01 00:00:00
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journal_title：European journal of gynaecological oncology
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journal_title：European journal of gynaecological oncology
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doi：
更新日期：1995-01-01 00:00:00
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journal_title：European journal of gynaecological oncology
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更新日期：2012-01-01 00:00:00
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doi：
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journal_title：European journal of gynaecological oncology
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doi：
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journal_title：European journal of gynaecological oncology
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doi：
更新日期：2002-01-01 00:00:00
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