Abstract:
:Extramedullary hematopoiesis (EH) is the ectopic production of myeloid, erythroid and megakaryocytic elements. In postfetal life it usually occurs in conditions with hyperactive, depleted or infiltrated marrow; it is extremely rare in the genital tract. We report a case of EH in the uterine isthmus (UI) which was found incidentally in a 40-year-old patient who presented with a right ovarian cyst and a history of a right modified radical mastectomy for infiltrating invasive lobular carcinoma one year earlier. The patient underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy. Microscopic examination of UI revealed foci of hematopoiesis, consisting of white blood cell precursors confirmed by positive chloroacetate-esterase staining. Bone marrow biospy showed diffuse infiltration secondary to breast cancer. Further work-up, including a bone scan, showed multiple metastases suggesting that the high degree of bone marrow infiltration by neoplasmatic cells had stimulated the EH. In conclusion, the unusual finding of EH in UI heralded widespread infiltration of bone marrow.
journal_name
Eur J Gynaecol Oncoljournal_title
European journal of gynaecological oncologyauthors
Varras M,Stylianido A,Akrivis Ch,Galanis P,Stefanaki S,Antoniou Nkeywords:
subject
Has Abstractpub_date
2002-01-01 00:00:00pages
227-30issue
3eissn
0392-2936issn
2709-0086journal_volume
23pub_type
杂志文章,评审abstract:PURPOSE:The aim of this study was to assess the outcomes of endometrial cancer patients treated with systematic surgery omitting paraarotic lymphadenectomy. PATIENTS AND METHODS:We retrospectively analyzed a consecutive series of 84 endometrioid-type endometrial cancer patients at FIGO Stage I, II or III without gross...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::The aim of this study is to draw attention to the possibility of the occurrence of a metastatic spread at the laparoscopic entrance site in patients suffering from a carcinoma of the ovary. This event has rarely been mentioned in medical literature before. A case is presented here in which a localized tumoral lesion a...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::A 33-year-old pregnant woman of 38 weeks' gestation with massive peritoneal ascites presented. A cesarean section was performed and a viable 3.100 g male infant was delivered. Biopsy of the nodular enlargements from the omentum revealed a malignant epithelial peritoneal mesothelioma. Malignant mesothelioma is a rare m...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章,评审
doi:
更新日期:2004-01-01 00:00:00
abstract::The preceding platinum-based combination chemotherapy could possibly reduce tumor masses, allowing for adequate surgical debulking in advanced ovarian cancer. In this study, a total of 18 patients with peritoneal carcinomatosis of the ovary were evaluated between 1996 and 2003. All patients underwent open biopsy for t...
journal_title:European journal of gynaecological oncology
pub_type: 临床试验,杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::We report a case of a pure ovarian leiomyosarcoma, a rare tumor that comprises less than 0.1% out of all the ovarian malignant tumors. ...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::Primitive omental leiomyomas are very rare. The primitive omental location of the leiomyoma is quite difficult to determine, with the possible presence of "parasite" myomas and of omental metastasizing myomas. Moreover, omental masses may be primitive or secondary metastasis from neoplasms. In this case report a primi...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2014-01-01 00:00:00
abstract::Twenty cases of ovarian carcinoma with normal-sized ovaries were examined histologically. Fifteen of them had metastatic disease of the peritoneal cavity and three of the remaining showed uterine involvement. Only in one case was the tumor confined to the ovary, but this patient had experienced systemic chemotherapy b...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::This paper describes the new "model" of the cervical cancer screening introduced as pilot study in the Białystok Province. The new programme was carried out to choose which "model" was better: computerized monitoring and invitation to the women to the outpatient clinic for the Pap-test performed by screeners on full i...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract:PURPOSE OF INVESTIGATION:The purpose of this study was to determine the prevalence of various human papillomavirus (HPV) types and its relationship with some risk factors among Turkish women. MATERIALS AND METHODS:A total of 673 patients were included in the study. Cervical samples were taken from the patients for rou...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2016-01-01 00:00:00
abstract::Tamoxifen, a nonsteroidal antiestrogen, is used for pre- and postmenopausal patients with breast cancer. Data on a possible association of endometrial pathologies with Tamoxifen treatment have been accumulating. The current literature and our experience are presented. ...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章,评审
doi:
更新日期:1997-01-01 00:00:00
abstract::Screening for ovarian cancer using tumor markers is simple but often associated with an increased rate of false negatives and a low rate of detection of early stage cancers. The transvaginal ultrasonic method, on the other hand, detects an increased number of Stage I cancers (about 70% of the total cancers detected), ...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract::This paper reports the results of a study of 50 menopausal women receiving hormonal replacement therapy. The majority (29) had surgical menopause; their mean age was 45.7 years. It was hypothesized that progestins could equilibrate the effects of the estrogenic stimulation on the mammary and endometrial target tissu...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract::Three cases of serous surface papillary carcinoma of the abdominopelvic peritoneum are presented. All of the patients were subjected to a relatively homogeneous management consisting of primary surgery and cisplatin based chemotherapy regimen. The second look procedures of two patients were found to be negative. Altho...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::This review is a short summary of the very long history of invasive and in situ carcinomas of the cervix. The items considered in this paper are the etiology of cervical cancer by a sexually transmitted agent proposed about 150 years ago by Domenico Rigoni Stern, the birth of radical surgery for the treatment of cervi...
journal_title:European journal of gynaecological oncology
pub_type: 历史文章,杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract:AIM OF THE STUDY:The analysis of acute and late toxicity of concurrent chemoradiotherapy (CCRT) for locally advanced cervical cancer (LACC) based on review of 120 patients treated in Centre of Oncology in Krakow between 2001 and 2007. MATERIALS AND METHODS:Medium age of the patients was 52 years (43-66). Overall, 12 p...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2014-01-01 00:00:00
abstract::The epidemiological behaviour of the invasive cancer of the uterine cervix in the Province of Trieste is analysed. During this study period, 488 cases of this neoplasia were diagnosed with an incidence rate standardized for the European population of 20.25 degrees/0000. This value is within the average ones recorded i...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract::Ovarian cancer is not the most frequent malignancy of female reproductive system, but it causes many deaths in women with this diagnosis. Mostly of the patients with ovarian cancer will have recurrence after first-line standard treatment containing surgery and chemotherapy. This article presents two cases with late re...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章,评审
doi:
更新日期:2015-01-01 00:00:00
abstract::Ovarian carcinoma is a malignancy with a poor prognosis especially in patients with advanced disease. The majority of patients with ovarian serous carcinoma are diagnosed in advanced stages. Palpable extraabdominal lymphadenopathy at the time of presentation is distinctly uncommon. This case report addresses a patient...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:To assess the impact of surgical staging on treatment modification and outcome in endometrial carcinoma (EC) patients. METHODS:Two groups of histologically confirmed clinical Stage I and II EC patients, diagnosed during two time periods (1976-1984 and 1985-1991), were retrospectively compared. Sixty-five pat...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract:PURPOSE OF INVESTIGATION:Epithelial ovarian tumors are usually mucinous or serous type, affecting nearly 1% of women during their lifetime. They may be regarded as benign, borderline or invasive according to pathological examination. Karyotypes of the tumor provide critical information about both the genetic predisposi...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract:AIM:Postoperative lymphorrhea is a major complication of axillary lymphadenectomy. The aim of our study was to evaluate the impact of type I collagen in postoperative lymphorrhea in mastectomy patients. METHODS:Eighty patients that underwent modified radical mastectomy for breast cancer were randomized in two groups. ...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2011-01-01 00:00:00
abstract::In the decade 1967-1977, 663 patients with different gynecologic neoplasms were admitted and treated at our Department. Because of the involvement of the urinary tract, urinary diversion was required in 41 cases. Ileal conduit was performed in 25 patients (20 affected by carcinoma of uterine cervix, 4 by adenocarcinom...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::On the basis of a case series of 577 patients affected by carcinoma of the endometrium treated during the period 1963-1989 in the Gynecologic Institute of the Padua University, the present work examines the reliability of endometrial biopsy aiming at the correct histopathologic diagnosis, through comparison with the s...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::Insulin-like growth factor-1 receptor (IGF-1R) regulates carcinogenesis and tumor development and is expressed in normal endometrium. Vascular endothelial growth factor C (VEGF-C) promotes lymph node metastasis. We investigated IGF-1R, VEGF-C and D2-40 in endometrial adenocarcinoma and the association between IGF-1R a...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract::According to the present guidelines for advanced epithelial ovarian cancer (EOC), bulky lymph nodes should be removed as part of the routine surgical staging and the primary goal being removal of all macroscopic tumor residuals. Furthermore, EOC-patients with bulky lymph node relapse seem to benefit from lymphadenecto...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract::In the present report we have evaluated two new serum tumour markers identified by monoclonal antibodies: TAG 72 and CA 15.3 in 62 patients with gynaecological carcinomas, in prevalence ovarian and 36 women with benign gynaecological diseases. Serum levels of both markers were determined using two immunoradiometric as...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::We studied a group of 24 uterine and ovarian neoplasms with the purpose to verify if any correlation could be established between chromosomal abnormalities, loss of heterozigosity (LOH) and microsatellite instability (MIN). Tumor specimens obtained from 24 women (12 affected by ovarian and 12 by uterine neoplasms) wer...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::The aim of this study was to describe the clinical features, methods of treatment and results of treatment among patients with primary invasive cancer. Twelve women in whom primary invasive cancer of the vagina was diagnosed between 1996 and 2001 were studied. The mean age of women with primary invasive vaginal cancer...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract:PURPOSE OF INVESTIGATION:To determine the expression of matrix metalloproteinase-9 (MMP-9) expression in malignant and borderline ovarian tumors and its correlation to prognosis. METHODS:Forty-five patients with primary epithelial ovarian tumors were enrolled in this retrospective study from 1988 to 2002. Only maligna...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::This report describes the case of a woman with early stage ovarian carcinoma who developed an isolated metastasis in the anterior abdominal wall following an apparent disease-free interval of ten years. The management of the case is discussed and important factors are highlighted. Comparison is also made to the phenom...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00