Fever-induced QTc prolongation and ventricular fibrillation in a healthy young man.

Abstract:

:Long QT syndrome is associated with lethal tachyarrhythmia that can lead to syncope, seizure, and sudden death. Congenital long QT syndrome is a genetic disorder, characterized by delayed cardiac repolarization and prolongation of the QT interval on the electrocardiogram (ECG). Type 2 congenital long QT is linked to mutations in the human ether a go-go-related gene (HERG). There are environmental triggers of adverse cardiac events such as emotional and acoustic stimuli, but fever can also be a potential trigger of life-threatening arrhythmias in long QT syndrome type 2 patients. Herein, we report a healthy young man who experienced fever-induced polymorphic ventricular tachycardia and QT interval prolongation.

journal_name

Yonsei Med J

journal_title

Yonsei medical journal

authors

Lim SM,Pak HN,Lee MH,Kim SS,Joung B

doi

10.3349/ymj.2011.52.6.1025

subject

Has Abstract

pub_date

2011-11-01 00:00:00

pages

1025-7

issue

6

eissn

0513-5796

issn

1976-2437

pii

2011111025

journal_volume

52

pub_type

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