Hydrogel expandable coils for vascular occlusion in congenital cardiovascular disease: a single center experience.

Abstract:

OBJECTIVE:  The objective of this study is to evaluate the safety and feasibility of the AZUR hydrogel-polymer coated platinum coil (hydrocoil) for vascular occlusion in patients with congenital cardiovascular disease (CCVD). DESIGN:  Retrospective case review. PATIENTS:  Eight patients with CCVD who underwent attempted vascular occlusion procedure with the hydrocoil at the University of Michigan between January 1, 2008 and March 1, 2011. Median patient age was 1.6 years (range 0.6-27.5 years) and median weight was 10.6 kg (3.9-74.8 kg). OUTCOME MEASURES:  Complete vascular occlusion of the target vessel was assessed at procedural completion with angiography and noninvasive imaging at follow-up. Key procedural variables and adverse events were also evaluated. RESULTS:  A total of 21 hydrocoils were successfully placed in seven vessels, in six patients. Vessels included four (57%) veno-venous collaterals, two (29%) aortopulmonary collaterals, and one (14%) main pulmonary artery. Hydrocoils could not be placed successfully in two patients, including one baffle leak and one veno-venous collateral. Pretreatment of the hydrocoil with steam to soften the coil, prior to vascular introduction, increased the likelihood of successful implant (100% vs. 60%). Complete occlusion was observed in 100% of vessels either at the time of catheterization or at follow-up. There were no complications attributable to the hydrocoil. CONCLUSIONS:  Hydrocoils are safe and effective devices that can be utilized for vascular occlusion in a variety of blood vessels in patients with CCVD. Coil pretreatment may increase the likelihood of procedural success.

journal_name

Congenit Heart Dis

journal_title

Congenital heart disease

authors

Goldstein BH,Aiyagari R,Bocks ML,Armstrong AK

doi

10.1111/j.1747-0803.2011.00583.x

subject

Has Abstract

pub_date

2012-05-01 00:00:00

pages

212-8

issue

3

eissn

1747-079X

issn

1747-0803

journal_volume

7

pub_type

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