Successful outcome in a HIV infected child presenting with Pre-B Acute Lymphoblastic Leukemia.

Abstract:

:The present case is a 5 y old child with Pre-B Acute Lymphoblastic Leukemia (ALL), presenting with fever, pallor, purpuric spots, hepato-splenomegaly and lymphadenopathy of 20 d duration. During re-induction chemotherapy, he developed atypical skin lesions diagnosed as Varicella Zoster infection. He and his parents tested positive for anti HIV antibody. He entered complete remission and Anti-retroviral therapy (ART) along with maintenance chemotherapy has been initiated 3 mon ago. Acute leukemia is rare in HIV and probably this is the first case of Pre-B Acute Leukemia in association with perinatally transmitted HIV.

journal_name

Indian J Pediatr

authors

Ghosh M,Banerjee M,Chakraborty S,Bhattacharyya S

doi

10.1007/s12098-011-0533-7

subject

Has Abstract

pub_date

2012-02-01 00:00:00

pages

267-9

issue

2

eissn

0019-5456

issn

0973-7693

journal_volume

79

pub_type

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