Environment sensing and response mediated by ABC transporters.

abstract：BACKGROUND:Litter size in pigs is a major factor affecting the profitability in the pig industry. The peri-implantation window in pigs is characterized by the coordinated interactions between the maternal uterine endometrium and the rapidly elongating conceptuses and represents a period of time during which a large per...

journal_title：BMC genomics

authors： Gu T,Zhu MJ,Schroyen M,Qu L,Nettleton D,Kuhar D,Lunney JK,Ross JW,Zhao SH,Tuggle CK

更新日期：2014-02-24 00:00:00

abstract：BACKGROUND:Ras-related proteins in brain (Rab)-family proteins are key members of the membrane trafficking pathway in cells. In addition, these proteins have been identified to have diverse functions such as cross-talking with different kinases and playing a role in cellular signaling. However, only a few Rab proteins ...

journal_title：BMC genomics

authors： Kumar S,Lee HJ,Park HS,Lee K

更新日期：2016-10-10 00:00:00

abstract：BACKGROUND:ATP binding cassette (ABC) systems are responsible for the import and export of a wide variety of molecules across cell membranes and comprise one of largest protein superfamilies found in prokarya, eukarya and archea. ABC systems play important roles in bacterial lifestyle, virulence and survival. In this s...

journal_title：BMC genomics

authors： Harland DN,Dassa E,Titball RW,Brown KA,Atkins HS

更新日期：2007-03-28 00:00:00

abstract：BACKGROUND:Next generation sequencing provides a powerful tool to study genome structure in species whose genomes are far from being completely sequenced. In this work we describe and compare different computational approaches to evaluate the repetitive component of the genome of sunflower, by using medium/low coverage...

journal_title：BMC genomics

authors： Natali L,Cossu RM,Barghini E,Giordani T,Buti M,Mascagni F,Morgante M,Gill N,Kane NC,Rieseberg L,Cavallini A

更新日期：2013-10-06 00:00:00

abstract：BACKGROUND:Cryptosporidium hominis is a dominant species for human cryptosporidiosis. Within the species, IbA10G2 is the most virulent subtype responsible for all C. hominis-associated outbreaks in Europe and Australia, and is a dominant outbreak subtype in the United States. In recent yearsIaA28R4 is becoming a major ...

journal_title：BMC genomics

authors： Guo Y,Tang K,Rowe LA,Li N,Roellig DM,Knipe K,Frace M,Yang C,Feng Y,Xiao L

更新日期：2015-04-18 00:00:00

abstract：BACKGROUND:Pitayas are currently attracting considerable interest as a tropical fruit with numerous health benefits. However, as a long-day plant, pitaya plants cannot flower in the winter season from November to April in Hainan, China. To harvest pitayas with high economic value in the winter season, it is necessary t...

journal_title：BMC genomics

authors： Xiong R,Liu C,Xu M,Wei SS,Huang JQ,Tang H

更新日期：2020-04-29 00:00:00

abstract：BACKGROUND:Long non-coding RNAs (lncRNAs) are a new class of regulatory molecules with roles in diverse biological processes. While much effort has been invested in the analysis of lncRNAs from established plant models Arabidopsis, maize, and rice, almost nothing is known about lncRNAs from fruit crops, including those...

journal_title：BMC genomics

authors： Kang C,Liu Z

更新日期：2015-10-19 00:00:00

abstract：BACKGROUND:Propionibacterium acnes and Staphylococcus epidermidis live in close proximity on human skin, and both bacterial species can be isolated from normal and acne vulgaris-affected skin sites. The antagonistic interactions between the two species are poorly understood, as well as the potential significance of bac...

journal_title：BMC genomics

authors： Christensen GJ,Scholz CF,Enghild J,Rohde H,Kilian M,Thürmer A,Brzuszkiewicz E,Lomholt HB,Brüggemann H

更新日期：2016-02-29 00:00:00

abstract：BACKGROUND:Cytoplasmic male sterility (CMS) is not only important for exploiting heterosis in crop plants, but also as a model for investigating nuclear-cytoplasmic interaction. CMS may be caused by mutations, rearrangement or recombination in the mitochondrial genome. Understanding the mitochondrial genome is often th...

journal_title：BMC genomics

authors： Heng S,Wei C,Jing B,Wan Z,Wen J,Yi B,Ma C,Tu J,Fu T,Shen J

更新日期：2014-04-30 00:00:00

abstract：BACKGROUND:Histone acetylation is a ubiquitous and reversible post-translational modification in eukaryotes and prokaryotes that is co-regulated by histone acetyltransferase (HAT) and histone deacetylase (HDAC). HAT activity is important for the modification of chromatin structure in eukaryotic cells, affecting gene tr...

journal_title：BMC genomics

authors： Gao S,Li L,Han X,Liu T,Jin P,Cai L,Xu M,Zhang T,Zhang F,Chen J,Yang J,Zhong K

更新日期：2021-01-11 00:00:00

abstract：BACKGROUND:The genomewide evaluation of genetic epistasis is a computationally demanding task, and a current challenge in Genetics. HFCC (Hypothesis-Free Clinical Cloning) is one of the methods that have been suggested for genomewide epistasis analysis. In order to perform an exhaustive search of epistasis, HFCC has im...

journal_title：BMC genomics

authors： Gayán J,González-Pérez A,Ruiz A

更新日期：2010-06-24 00:00:00

abstract：BACKGROUND:The obligate intracellular parasite Toxoplasma gondii establishes a life-long chronic infection within any warm-blooded host. After ingestion of an encysted parasite, T. gondii disseminates throughout the body as a rapidly replicating form during acute infection. Over time and after stimulation of the host i...

journal_title：BMC genomics

authors： Pittman KJ,Aliota MT,Knoll LJ

更新日期：2014-09-20 00:00:00

abstract：BACKGROUND:Williams syndrome transcription factor (WSTF) is a multifaceted protein that is involved in several nuclear processes, including replication, transcription, and the DNA damage response. WSTF participates in a chromatin-remodeling complex with the ISWI ATPase, SNF2H, and is thought to contribute to the mainte...

journal_title：BMC genomics

authors： Culver-Cochran AE,Chadwick BP

更新日期：2013-10-29 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs), short approximately 21-nucleotide RNA molecules, play an important role in post-transcriptional regulation of gene expression. The number of known miRNA hairpins registered in the miRBase database is rapidly increasing, but recent reports suggest that many miRNAs with restricted temporal ...

journal_title：BMC genomics

authors： van der Burgt A,Fiers MW,Nap JP,van Ham RC

更新日期：2009-04-30 00:00:00

abstract：BACKGROUND:New and improved antimicrobial countermeasures are urgently needed to counteract increased resistance to existing antimicrobial treatments and to combat currently untreatable or new emerging infectious diseases. We demonstrate that computational comparative genomics, together with experimental screening, can...

journal_title：BMC genomics

authors： Stubben CJ,Duffield ML,Cooper IA,Ford DC,Gans JD,Karlyshev AV,Lingard B,Oyston PC,de Rochefort A,Song J,Wren BW,Titball RW,Wolinsky M

更新日期：2009-10-29 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are an abundant class of small single-stranded non-coding RNA molecules ranging from 18 to 24 nucleotides. They negatively regulate gene expression at the post-transcriptional level and play key roles in many biological processes, including skeletal development and cartilage maturation. In...

journal_title：BMC genomics

authors： Desjardin C,Vaiman A,Mata X,Legendre R,Laubier J,Kennedy SP,Laloe D,Barrey E,Jacques C,Cribiu EP,Schibler L

更新日期：2014-09-17 00:00:00

abstract：BACKGROUND:Decades of intensive genetic selection in the domestic chicken (Gallus gallus domesticus) have enabled the remarkable rapid growth of today's broiler (meat-type) chickens. However, this enhanced growth rate was accompanied by several unfavorable traits (i.e., increased visceral fatness, leg weakness, and dis...

journal_title：BMC genomics

authors： Resnyk CW,Carré W,Wang X,Porter TE,Simon J,Le Bihan-Duval E,Duclos MJ,Aggrey SE,Cogburn LA

更新日期：2017-08-16 00:00:00

abstract：BACKGROUND:The out of Africa hypothesis has gained generalized consensus. However, many specific questions remain unsettled. To know whether the two M and N macrohaplogroups that colonized Eurasia were already present in Africa before the exit is puzzling. It has been proposed that the east African clade M1 supports a ...

journal_title：BMC genomics

authors： González AM,Larruga JM,Abu-Amero KK,Shi Y,Pestano J,Cabrera VM

更新日期：2007-07-09 00:00:00

abstract：BACKGROUND:Evolution of novel protein-coding genes is the bedrock of adaptive evolution. Recently, we identified six protein-coding genes with similar signal sequence from Schistosoma japonicum egg stage mRNA using signal sequence trap (SST). To find the mechanism underlying the origination of these genes with similar ...

journal_title：BMC genomics

authors： Mbanefo EC,Chuanxin Y,Kikuchi M,Shuaibu MN,Boamah D,Kirinoki M,Hayashi N,Chigusa Y,Osada Y,Hamano S,Hirayama K

更新日期：2012-06-20 00:00:00

abstract：BACKGROUND:During the evolution of mammalian sex chromosomes, the degeneration of Y-linked homologs has led to a dosage imbalance between X-linked and autosomal genes. The evolutionary resolution to such dosage imbalance, as hypothesized by Susumu Ohno fifty years ago, should be doubling the expression of X-linked gene...

journal_title：BMC genomics

authors： Yang JR,Chen X

更新日期：2019-01-14 00:00:00

abstract：BACKGROUND:The orange pigmentation of the agar cultures of many Fusarium species is due to the production of carotenoids, terpenoid pigments whose synthesis is stimulated by light. The genes of the carotenoid pathway and their regulation have been investigated in detail in Fusarium fujikuroi. In this and other Fusarium...

journal_title：BMC genomics

authors： Ruger-Herreros M,Parra-Rivero O,Pardo-Medina J,Romero-Campero FJ,Limón MC,Avalos J

更新日期：2019-01-21 00:00:00

abstract：BACKGROUND:Low iron bioavailability is a common feature of ocean surface water and therefore micro-algae developed original strategies to optimize iron uptake and metabolism. The marine picoeukaryotic green alga Ostreococcus tauri is a very good model for studying physiological and genetic aspects of the adaptation of ...

journal_title：BMC genomics

authors： Lelandais G,Scheiber I,Paz-Yepes J,Lozano JC,Botebol H,Pilátová J,Žárský V,Léger T,Blaiseau PL,Bowler C,Bouget FY,Camadro JM,Sutak R,Lesuisse E

更新日期：2016-05-03 00:00:00

abstract：BACKGROUND:Regions of the genome that are under evolutionary constraint across multiple species have previously been used to identify functional sequences in the human genome. Furthermore, it is known that there is an inverse relationship between evolutionary constraint and the allele frequency of a mutation segregatin...

journal_title：BMC genomics

authors： Hodgkinson A,Casals F,Idaghdour Y,Grenier JC,Hernandez RD,Awadalla P

更新日期：2013-07-23 00:00:00

abstract：BACKGROUND:One of the key characters of social insects is the division of labor, in which different tasks are allocated to various castes. In termites, one of the representative groups of social insects, morphological differences as well as behavioral differences can be recognized among castes. However, very little is ...

journal_title：BMC genomics

authors： Ishikawa Y,Okada Y,Ishikawa A,Miyakawa H,Koshikawa S,Miura T

更新日期：2010-05-20 00:00:00

abstract：BACKGROUND:Genome-wide association studies have revealed associations between single-nucleotide polymorphisms (SNPs) and phenotypes such as disease symptoms and drug tolerance. To address the small sample size for rare variants, association studies tend to group gene or pathway level variants and evaluate the effect on...

journal_title：BMC genomics

authors： Hasegawa T,Kojima K,Kawai Y,Misawa K,Mimori T,Nagasaki M

更新日期：2016-09-21 00:00:00

abstract：BACKGROUND:Carboxylesterase is a multifunctional superfamily and ubiquitous in all living organisms, including animals, plants, insects, and microbes. It plays important roles in xenobiotic detoxification, and pheromone degradation, neurogenesis and regulating development. Previous studies mainly used Dipteran Drosophi...

journal_title：BMC genomics

authors： Yu QY,Lu C,Li WL,Xiang ZH,Zhang Z

更新日期：2009-11-24 00:00:00

abstract：BACKGROUND:Mitochondria are organelles that fulfill a fundamental role in cell bioenergetics, as well as in other processes like cell signaling and death. Small non-coding RNAs (sncRNA) are now being considered as pivotal post-transcriptional regulators, widening the landscape of their diversity and functions. In mamma...

journal_title：BMC genomics

authors： Larriba E,Rial E,Del Mazo J

更新日期：2018-08-28 00:00:00

abstract：BACKGROUND:In our previous study, Citrobacter werkmanii BF-6 was isolated from an industrial spoilage sample and demonstrated an excellent ability to form biofilms, which could be affected by various environmental factors. However, the genome sequence of this organism has not been reported so far. RESULTS:We report th...

journal_title：BMC genomics

authors： Zhou G,Peng H,Wang YS,Huang XM,Xie XB,Shi QS

更新日期：2017-10-10 00:00:00

abstract：BACKGROUND:Matrix attachment regions (MAR) are the sites on genomic DNA that interact with the nuclear matrix. There is increasing evidence for the involvement of MAR in regulation of gene expression. The unsuitability of experimental detection of MAR for genome-wide analyses has led to the development of computational...

journal_title：BMC genomics

authors： Anthony A,Blaxter M

更新日期：2007-11-15 00:00:00

abstract：BACKGROUND:Zoysia matrella, widely used in lawns and sports fields, is of great economic and ecological value. Z. matrella is an allotetraploid species (2n = 4x = 40) in the genus zoysia under the subfamily Chloridoideae. Despite its ecological impacts and economic importance, the subfamily Chloridoideae has received l...

journal_title：BMC genomics

authors： Huang X,Wang F,Singh R,Reinert JA,Engelke MC,Genovesi AD,Chandra A,Yu Q

更新日期：2016-08-08 00:00:00