Testis-Specific GTPase (TSG): An oligomeric protein.

abstract：BACKGROUND:Gene expression analysis by reverse transcription quantitative PCR (qPCR) is the most widely used method for analyzing the expression of a moderate number of genes and also for the validation of microarray results. Several issues are crucial for a successful qPCR study, particularly the selection of internal...

journal_title：BMC genomics

authors： Robledo D,Hernández-Urcera J,Cal RM,Pardo BG,Sánchez L,Martínez P,Viñas A

更新日期：2014-08-04 00:00:00

abstract：BACKGROUND:Modifications of RNA bases have been found in some mRNAs and non-coding RNAs including rRNAs, tRNAs, and snRNAs, where modified bases are important for RNA function. Little is known about RNA base modifications in Arabidopsis thaliana. RESULTS:In the current work, we carried out a bioinformatics analysis of...

journal_title：BMC genomics

authors： Iida K,Jin H,Zhu JK

更新日期：2009-04-09 00:00:00

abstract：BACKGROUND:Cultivated peanut (Arachis hypogaea L.) is an important oil and protein crop, but it has low disease resistance; therefore, it is important to reveal the number, sequence features, function, and evolution of genes that confer resistance. Nucleotide-binding site-leucine-rich repeats (NBS-LRRs) are resistance ...

journal_title：BMC genomics

authors： Song H,Guo Z,Hu X,Qian L,Miao F,Zhang X,Chen J

更新日期：2019-11-13 00:00:00

abstract：BACKGROUND:Aphid (Macrosiphoniella sanbourni) stress drastically influences the yield and quality of chrysanthemum, and grafting has been widely used to improve tolerance to biotic and abiotic stresses. However, the effect of grafting on the resistance of chrysanthemum to aphids remains unclear. Therefore, we used the ...

journal_title：BMC genomics

authors： Zhang XY,Sun XZ,Zhang S,Yang JH,Liu FF,Fan J

更新日期：2019-10-25 00:00:00

abstract：BACKGROUND:Cattle and other ruminants have evolved the ability to derive most of their metabolic energy requirement from otherwise indigestible plant matter through a symbiotic relationship with plant fibre degrading microbes within a specialised fermentation chamber, the rumen. The genetic changes underlying the evolu...

journal_title：BMC genomics

authors： Wheeler TT,Hood KA,Maqbool NJ,McEwan JC,Bingle CD,Zhao S

更新日期：2007-03-15 00:00:00

abstract：BACKGROUND:Designing sustainable animal production systems that better balance productivity and resistance to disease is a major concern. In order to address questions related to immunity and resistance to disease in pig, it is necessary to increase knowledge on its immune system and to produce efficient tools dedicate...

journal_title：BMC genomics

authors： Gao Y,Flori L,Lecardonnel J,Esquerré D,Hu ZL,Teillaud A,Lemonnier G,Lefèvre F,Oswald IP,Rogel-Gaillard C

更新日期：2010-05-11 00:00:00

abstract：BACKGROUND:The Bacillus cereus sensu lato group currently includes seven species (B. cereus, B. anthracis, B. mycoides, B. pseudomycoides, B. thuringiensis, B. weihenstephanensis and B. cytotoxicus) that recent phylogenetic and phylogenomic analyses suggest are likely a single species, despite their varied phenotypes. ...

journal_title：BMC genomics

authors： Scott E 2nd,Dyer DW

更新日期：2012-10-22 00:00:00

abstract：BACKGROUND:The importance of Indian germplasm as origin and primary center of diversity of cultivated melon is widely accepted. Genetic diversity of several collections from Indian has been studied previously, although an integrated analysis of these collections in a global diversity perspective has not been possible. ...

journal_title：BMC genomics

authors： Gonzalo MJ,Díaz A,Dhillon NPS,Reddy UK,Picó B,Monforte AJ

更新日期：2019-06-03 00:00:00

abstract：BACKGROUND:It is believed that the main factors of low prenatal growth in mammals are genetic and environmental. We used isogenic mice maintained in standard conditions to analyze how natural non-genetic microsomia (low birth weight) is produced in inbred mice and its long term effect on health. To better understand th...

journal_title：BMC genomics

authors： Miranda A,López-Cardona AP,Laguna-Barraza R,Calle A,López-Vidriero I,Pintado B,Gutiérrez-Adán A

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Bacteriophages that infect the opportunistic pathogen Pseudomonas aeruginosa have been classified into several groups. One of them, which includes temperate phage particles with icosahedral heads and long flexible tails, bears genomes whose architecture and replication mechanism, but not their nucleotide seq...

journal_title：BMC genomics

authors： Cazares A,Mendoza-Hernández G,Guarneros G

更新日期：2014-12-19 00:00:00

abstract：BACKGROUND:Aeromonas salmonicida subsp. salmonicida is a ubiquitous psychrophilic waterborne bacterium and a fish pathogen. The numerous mobile elements, especially insertion sequences (IS), in its genome promote rearrangements that impact its phenotype. One of the main virulence factors of this bacterium, its type thr...

journal_title：BMC genomics

authors： Tanaka KH,Vincent AT,Emond-Rheault JG,Adamczuk M,Frenette M,Charette SJ

更新日期：2017-07-12 00:00:00

abstract：BACKGROUND:Exome sequencing has transformed human genetic analysis and may do the same for other vertebrate model systems. However, a major challenge is sifting through the large number of sequence variants to identify the causative mutation for a given phenotype. In models like Xenopus tropicalis, an incomplete and oc...

journal_title：BMC genomics

authors： del Viso F,Bhattacharya D,Kong Y,Gilchrist MJ,Khokha MK

更新日期：2012-11-21 00:00:00

abstract：BACKGROUND:Leaf blight caused by Calonectria spp. is one of the most destructive diseases to affect Eucalyptus nurseries and plantations. These pathogens mainly attack Eucalyptus, a tree with a diversity of secondary metabolites employed as defense-related phytoalexins. To unravel the fungal adaptive mechanisms to vari...

journal_title：BMC genomics

authors： Ye X,Zhong Z,Liu H,Lin L,Guo M,Guo W,Wang Z,Zhang Q,Feng L,Lu G,Zhang F,Chen Q

更新日期：2018-05-10 00:00:00

abstract：BACKGROUND:Burkholderia cenocepacia is an opportunistic pathogen causing life-threatening infections in patients with cystic fibrosis. The bacterium survives within macrophages by interfering with endocytic trafficking and delaying the maturation of the B. cenocepacia-containing phagosome. We hypothesize that B. cenoce...

journal_title：BMC genomics

authors： Tolman JS,Valvano MA

更新日期：2012-02-09 00:00:00

abstract：BACKGROUND:Massively-parallel sequencing at depth is now enabling tumor heterogeneity and evolution to be characterized in unprecedented detail. Tracking these changes in clonal architecture often provides insight into therapeutic response and resistance. In complex cases involving multiple timepoints, standard visuali...

journal_title：BMC genomics

authors： Miller CA,McMichael J,Dang HX,Maher CA,Ding L,Ley TJ,Mardis ER,Wilson RK

更新日期：2016-11-07 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are small non-coding RNA molecules that downregulate gene expression by base pairing to the 3'-untranslated region (UTR) of target messenger RNAs (mRNAs). Up to now, rare information for the miRNAs is available in decapod crustaceans. Our previous studies showed that many miRNA-binding sit...

journal_title：BMC genomics

authors： Song YN,Shi LL,Liu ZQ,Qiu GF

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Marek's disease (MD) is a lymphoproliferative disease in chickens caused by Marek's disease virus (MDV) and characterized by T cell lymphoma and infiltration of lymphoid cells into various organs such as liver, spleen, peripheral nerves and muscle. Resistance to MD and disease risk have long been thought to ...

journal_title：BMC genomics

authors： Yu Y,Luo J,Mitra A,Chang S,Tian F,Zhang H,Yuan P,Zhou H,Song J

更新日期：2011-10-12 00:00:00

abstract：BACKGROUND:miRNAs are small, non-coding RNA molecules that mainly act as negative regulators of target gene messages. Due to their regulatory functions, they have lately been implicated in several diseases, including malignancies. Roughly half of known miRNA genes are located within previously annotated protein-coding ...

journal_title：BMC genomics

authors： Hinske LC,Galante PA,Kuo WP,Ohno-Machado L

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation and destruction of synovial joints. RA affects up to 1 % of the population worldwide. Currently, there are no drugs that can cure RA or achieve sustained remission. The unknown cause of the disease represents a significan...

journal_title：BMC genomics

authors： Xu R,Wang Q

更新日期：2016-08-22 00:00:00

abstract：BACKGROUND:Intellectual Disability (ID) is among the most common global disorders, yet etiology is unknown in ~30% of patients despite clinical assessment. Whole genome sequencing (WGS) is able to interrogate the entire genome, providing potential to diagnose idiopathic patients. METHODS:We conducted WGS on eight chil...

journal_title：BMC genomics

authors： Zahir FR,Mwenifumbo JC,Chun HE,Lim EL,Van Karnebeek CDM,Couse M,Mungall KL,Lee L,Makela N,Armstrong L,Boerkoel CF,Langlois SL,McGillivray BM,Jones SJM,Friedman JM,Marra MA

更新日期：2017-05-24 00:00:00

abstract：BACKGROUND:Abnormalities of pre-mRNA splicing are increasingly recognized as an important mechanism through which gene mutations cause disease. However, apart from the mutations in the donor and acceptor sites, the effects on splicing of other sequence variations are difficult to predict. Loosely defined exonic and int...

journal_title：BMC genomics

authors： Lastella P,Surdo NC,Resta N,Guanti G,Stella A

更新日期：2006-09-22 00:00:00

abstract：BACKGROUND:Azadirachtin A is a triterpenoid from neem tree exhibiting excellent activities against over 600 insect species in agriculture. The production of azadirachtin A depends on extraction from neem tissues, which is not an eco-friendly and sustainable process. The low yield and discontinuous supply of azadirachti...

journal_title：BMC genomics

authors： Wang H,Wang N,Huo Y

更新日期：2020-10-28 00:00:00

abstract：BACKGROUND:Genome-scale metabolic models (GSMM) integrating transcriptomics have been widely used to study cancer metabolism. This integration is achieved through logical rules that describe the association between genes, proteins, and reactions (GPRs). However, current gene-to-reaction formulation lacks the stoichiome...

journal_title：BMC genomics

authors： Marín de Mas I,Torrents L,Bedia C,Nielsen LK,Cascante M,Tauler R

更新日期：2019-08-15 00:00:00

abstract：BACKGROUND:Bacteroides thetaiotaomicron, a predominant member of the human gut microbiota, is characterized by its ability to utilize a wide variety of polysaccharides using the extensive saccharolytic machinery that is controlled by an expanded repertoire of transcription factors (TFs). The availability of genomic seq...

journal_title：BMC genomics

authors： Ravcheev DA,Godzik A,Osterman AL,Rodionov DA

更新日期：2013-12-12 00:00:00

abstract：BACKGROUND:Following the association of Cronobacter spp. to several publicized fatal outbreaks in neonatal intensive care units of meningitis and necrotising enterocolitis, the World Health Organization (WHO) in 2004 requested the establishment of a molecular typing scheme to enable the international control of the org...

journal_title：BMC genomics

authors： Forsythe SJ,Dickins B,Jolley KA

更新日期：2014-12-16 00:00:00

abstract：BACKGROUND:Age-related gene expression patterns of Homo sapiens as well as of model organisms such as Mus musculus, Saccharomyces cerevisiae, Caenorhabditis elegans and Drosophila melanogaster are a basis for understanding the genetic mechanisms of ageing. For an effective analysis and interpretation of expression prof...

journal_title：BMC genomics

authors： Hofer E,Laschober GT,Hackl M,Thallinger GG,Lepperdinger G,Grillari J,Jansen-Dürr P,Trajanoski Z

更新日期：2011-05-24 00:00:00

abstract：BACKGROUND:Unveiling fungal genome structure and function reveals the potential biotechnological use of fungi. Trichoderma harzianum is a powerful CAZyme-producing fungus. We studied the genomic regions in T. harzianum IOC3844 containing CAZyme genes, transcription factors and transporters. RESULTS:We used bioinformat...

journal_title：BMC genomics

authors： Ferreira Filho JA,Horta MAC,Dos Santos CA,Almeida DA,Murad NF,Mendes JS,Sforça DA,Silva CBC,Crucello A,de Souza AP

更新日期：2020-11-02 00:00:00

abstract：BACKGROUND:Europeans and American Indians were major genetic ancestry of Hispanics in the U.S. These ancestral groups have markedly different incidence rates and outcomes in many types of cancers. Therefore, the genetic admixture may cause biased genetic association study with cancer susceptibility variants specificall...

journal_title：BMC genomics

authors： Wang LJ,Zhang CW,Su SC,Chen HH,Chiu YC,Lai Z,Bouamar H,Ramirez AG,Cigarroa FG,Sun LZ,Chen Y

更新日期：2019-12-30 00:00:00

abstract：BACKGROUND:Streptococcus uberis, a Gram positive bacterial pathogen responsible for a significant proportion of bovine mastitis in commercial dairy herds, colonises multiple body sites of the cow including the gut, genital tract and mammary gland. Comparative analysis of the complete genome sequence of S. uberis strain...

journal_title：BMC genomics

authors： Ward PN,Holden MT,Leigh JA,Lennard N,Bignell A,Barron A,Clark L,Quail MA,Woodward J,Barrell BG,Egan SA,Field TR,Maskell D,Kehoe M,Dowson CG,Chanter N,Whatmore AM,Bentley SD,Parkhill J

更新日期：2009-01-28 00:00:00

abstract：BACKGROUND:Salmonella enterica is a significant foodborne pathogen, which can be transmitted via several distinct routes, and reports on acquisition of antimicrobial resistance (AMR) are increasing. To better understand the association between human Salmonella clinical isolates and the potential environmental/animal re...

journal_title：BMC genomics

authors： Pornsukarom S,van Vliet AHM,Thakur S

更新日期：2018-11-06 00:00:00