"Integrative genomic analysis of the bioprospection of regulators and accessory enzymes associated with cellulose degradation in a filamentous fungus (Trichoderma harzianum)".

abstract：BACKGROUND:Gibel carp is an important aquaculture species in China, and a herpesvirus, called as Carassius auratus herpesvirus (CaHV), has hampered the aquaculture development. Diverse gynogenetic clones of gibel carp have been identified or created, and some of them have been used as aquaculture varieties, but their r...

journal_title：BMC genomics

authors： Gao FX,Wang Y,Zhang QY,Mou CY,Li Z,Deng YS,Zhou L,Gui JF

更新日期：2017-07-24 00:00:00

abstract：BACKGROUND:About 6 million Americans suffer from heart failure and 70% of heart failure cases are caused by myocardial infarction (MI). Following myocardial infarction, increased cytokines induce two major types of macrophages: classically activated macrophages which contribute to extracellular matrix destruction and a...

journal_title：BMC genomics

authors： Wang Y,Yang T,Ma Y,Halade GV,Zhang J,Lindsey ML,Jin YF

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Short-read resequencing of genomes produces abundant information of the genetic variation of individuals. Due to their numerous nature, these variants are rarely exhaustively validated. Furthermore, low levels of undetected variant miscalling will have a systematic and disproportionate impact on the interpre...

journal_title：BMC genomics

authors： Field MA,Burgio G,Chuah A,Al Shekaili J,Hassan B,Al Sukaiti N,Foote SJ,Cook MC,Andrews TD

更新日期：2019-07-16 00:00:00

abstract：BACKGROUND:Acinetobacter baumannii is a major health problem. The most common infection caused by A. baumannii is hospital acquired pneumonia, and the associated mortality rate is approximately 50%. Neither in vivo nor ex vivo expression profiling has been performed at the proteomic or transcriptomic level for pneumoni...

journal_title：BMC genomics

authors： Méndez JA,Mateos J,Beceiro A,Lopez M,Tomás M,Poza M,Bou G

更新日期：2015-05-30 00:00:00

abstract：BACKGROUND:The plastome of medicinal and endangered species in Kingdom of Saudi Arabia, Barleria prionitis was sequenced. The plastome was compared with that of seven Acanthoideae species in order to describe the plastome, spot the microsatellite, assess the dissimilarities within the sampled plastomes and to infer the...

journal_title：BMC genomics

authors： Alzahrani DA,Yaradua SS,Albokhari EJ,Abba A

更新日期：2020-06-06 00:00:00

abstract：BACKGROUND:Microarray technology is limited to monitoring the expression of previously annotated genes that have corresponding probes on the array. Computationally annotated genes have not fully been validated, because ESTs and full-length cDNAs cannot cover entire transcribed regions. Here, mRNA-Seq (an Illumina cDNA ...

journal_title：BMC genomics

authors： Mizuno H,Kawahara Y,Sakai H,Kanamori H,Wakimoto H,Yamagata H,Oono Y,Wu J,Ikawa H,Itoh T,Matsumoto T

更新日期：2010-12-02 00:00:00

abstract：BACKGROUND:Plants contain significant quantities of small RNAs (sRNAs) derived from various sRNA biogenesis pathways. Many of these sRNAs play regulatory roles in plants. Previous analysis revealed that numerous sRNAs in corn, rice and soybean seeds have high sequence similarity to animal genes. However, exogenous RNA ...

journal_title：BMC genomics

authors： Zhang Y,Wiggins BE,Lawrence C,Petrick J,Ivashuta S,Heck G

更新日期：2012-08-08 00:00:00

abstract：BACKGROUND:Teleost intestine is crucial for seawater acclimation by sensing osmolality of imbibed seawater and regulating drinking and water/ion absorption. Regulatory genes for transforming intestinal function have not been identified. A transcriptomic approach was used to search for such genes in the intestine of eur...

journal_title：BMC genomics

authors： Wong MK,Ozaki H,Suzuki Y,Iwasaki W,Takei Y

更新日期：2014-12-18 00:00:00

abstract：BACKGROUND:Obesity affects quality of life and life expectancy and is associated with cardiovascular disorders, cancer, diabetes, reproductive disorders in women, prostate diseases in men, and congenital anomalies in children. The use of single nucleotide polymorphism (SNP) markers of diseases and drug responses (i.e.,...

journal_title：BMC genomics

authors： Arkova OV,Ponomarenko MP,Rasskazov DA,Drachkova IA,Arshinova TV,Ponomarenko PM,Savinkova LK,Kolchanov NA

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Screening for differentially expressed genes on the genomic scale and comparative analysis of the expression profiles of orthologous genes between species to study gene function and regulation are becoming increasingly feasible. Expressed sequence tags (ESTs) are an excellent source of data for such studies ...

journal_title：BMC genomics

authors： Pao SY,Lin WL,Hwang MJ

更新日期：2006-04-21 00:00:00

abstract：BACKGROUND:One of the most important global pathogens infecting all age groups is Streptococcus pneumoniae (the 'pneumococcus'). Pneumococci reside in the paediatric nasopharynx, where they compete for space and resources, and one competition strategy is to produce a bacteriocin (antimicrobial peptide or protein) to at...

journal_title：BMC genomics

authors： Bogaardt C,van Tonder AJ,Brueggemann AB

更新日期：2015-07-28 00:00:00

abstract：BACKGROUND:The most critical step in the pearl formation during aquaculture is issued to the proliferation and differentiation of outer epithelial cells of mantle graft into pearl sac. This pearl sac secretes various matrix proteins to produce pearls by a complex physiological process which has not been well-understood...

journal_title：BMC genomics

authors： Mariom,Take S,Igarashi Y,Yoshitake K,Asakawa S,Maeyama K,Nagai K,Watabe S,Kinoshita S

更新日期：2019-03-25 00:00:00

abstract：BACKGROUND:Genome-wide association studies show that most human traits and diseases are caused by a combination of environmental and genetic causes, with each one of these having a relatively small effect. In contrast, most therapies based on macromolecules like antibodies, antisense oligonucleotides or peptides focus ...

journal_title：BMC genomics

authors： Varela MA

更新日期：2015-07-18 00:00:00

abstract：BACKGROUND:Color polymorphism in the nacre of pteriomorphian bivalves is of great interest for the pearl culture industry. The nacreous layer of the Polynesian black-lipped pearl oyster Pinctada margaritifera exhibits a large array of color variation among individuals including reflections of blue, green, yellow and pi...

journal_title：BMC genomics

authors： Lemer S,Saulnier D,Gueguen Y,Planes S

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Fatty liver is a high incidence of perinatal disease in dairy cows caused by negative energy balance, which seriously threatens the postpartum health and milk production. It has been reported that lysine acetylation plays an important role in substance and energy metabolism. Predictably, most metabolic proce...

journal_title：BMC genomics

authors： Le-Tian Z,Cheng-Zhang H,Xuan Z,Zhang Q,Zhen-Gui Y,Qing-Qing W,Sheng-Xuan W,Zhong-Jin X,Ran-Ran L,Ting-Jun L,Zhong-Qu S,Zhong-Hua W,Ke-Rong S

更新日期：2020-06-26 00:00:00

abstract：BACKGROUND:One challenge of systems biology is the integration of new data into the preexisting, and then re-interpretation of the integrated data. Here we use readily available metaanalysis computational methods to integrate new data on the transcriptomic effects of EGF in primary human epidermal keratinocytes with pr...

journal_title：BMC genomics

authors： Blumenberg M

更新日期：2013-02-08 00:00:00

abstract：BACKGROUND:Fish under intensive culture conditions are exposed to a variety of acute and chronic stressors, including high rearing densities, sub-optimal water quality, and severe thermal fluctuations. Such stressors are inherent in aquaculture production and can induce physiological responses with adverse effects on t...

journal_title：BMC genomics

authors： Sánchez CC,Weber GM,Gao G,Cleveland BM,Yao J,Rexroad CE 3rd

更新日期：2011-12-21 00:00:00

abstract：BACKGROUND:The ubiquitin-conjugating enzyme HR6B is required for spermatogenesis in mouse. Loss of HR6B results in aberrant histone modification patterns on the trancriptionally silenced X and Y chromosomes (XY body) and on centromeric chromatin in meiotic prophase. We studied the relationship between these chromatin m...

journal_title：BMC genomics

authors： Mulugeta Achame E,Wassenaar E,Hoogerbrugge JW,Sleddens-Linkels E,Ooms M,Sun ZW,van IJcken WF,Grootegoed JA,Baarends WM

更新日期：2010-06-10 00:00:00

abstract：BACKGROUND:During eukaryotic genome evolution, tandem gene duplication is the most frequent event giving rise to clustered gene families. However, how expression divergence between tandemly duplicated genes has emerged and maintained remain unclear. In particular, it is unknown if epigenetic regulators have been involv...

journal_title：BMC genomics

authors： Liao BY,Chang A

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Single-cell gene expression measurements offer opportunities in deriving mechanistic understanding of complex diseases, including cancer. However, due to the complex regulatory machinery of the cell, gene regulatory network (GRN) model inference based on such data still manifests significant uncertainty. RE...

journal_title：BMC genomics

authors： Hajiramezanali E,Imani M,Braga-Neto U,Qian X,Dougherty ER

更新日期：2019-06-13 00:00:00

abstract：BACKGROUND:It is believed that the main factors of low prenatal growth in mammals are genetic and environmental. We used isogenic mice maintained in standard conditions to analyze how natural non-genetic microsomia (low birth weight) is produced in inbred mice and its long term effect on health. To better understand th...

journal_title：BMC genomics

authors： Miranda A,López-Cardona AP,Laguna-Barraza R,Calle A,López-Vidriero I,Pintado B,Gutiérrez-Adán A

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Gene duplication is an important biological phenomenon associated with genomic redundancy, degeneration, specialization, innovation, and speciation. After duplication, both copies continue functioning when natural selection favors duplicated protein function or expression, or when mutations make them functio...

journal_title：BMC genomics

authors： Chain FJ,Dushoff J,Evans BJ

更新日期：2011-12-12 00:00:00

abstract：BACKGROUND:Small RNAs (sRNAs) have emerged as important regulatory molecules and have been studied in several bacteria. However, to date, there have been no whole-transcriptome studies on sRNAs in any of the Soft Rot Enterobacteriaceae (SRE) group of pathogens. Although the main ecological niches for these pathogens ar...

journal_title：BMC genomics

authors： Kwenda S,Gorshkov V,Ramesh AM,Naidoo S,Rubagotti E,Birch PR,Moleleki LN

更新日期：2016-01-12 00:00:00

abstract：BACKGROUND:Cell lines are an indispensable tool in biomedical research and often used as surrogates for tissues. Although there are recognized important cellular and transcriptomic differences between cell lines and tissues, a systematic overview of the differences between the regulatory processes of a cell line and th...

journal_title：BMC genomics

authors： Lopes-Ramos CM,Paulson JN,Chen CY,Kuijjer ML,Fagny M,Platig J,Sonawane AR,DeMeo DL,Quackenbush J,Glass K

更新日期：2017-09-12 00:00:00

abstract：BACKGROUND:Malaria caused by Plasmodium vivax is an experimentally neglected severe disease with a substantial burden on human health. Because of technical limitations, little is known about the biology of this important human pathogen. Whole genome analysis methods on patient-derived material are thus likely to have a...

journal_title：BMC genomics

authors： Bright AT,Tewhey R,Abeles S,Chuquiyauri R,Llanos-Cuentas A,Ferreira MU,Schork NJ,Vinetz JM,Winzeler EA

更新日期：2012-06-21 00:00:00

abstract：BACKGROUND:Spiders (Order Araneae) are essential predators in every terrestrial ecosystem largely because they have evolved potent arsenals of silk and venom. Spider silks are high performance materials made almost entirely of proteins, and thus represent an ideal system for investigating genome level evolution of nove...

journal_title：BMC genomics

authors： Clarke TH,Garb JE,Hayashi CY,Haney RA,Lancaster AK,Corbett S,Ayoub NA

更新日期：2014-05-23 00:00:00

abstract：BACKGROUND:Vinyl chloride is a widespread groundwater pollutant and Group 1 carcinogen. A previous comparative genomic analysis revealed that the vinyl chloride reductase operon, vcrABC, of Dehalococcoides sp. strain VS is embedded in a horizontally-acquired genomic island that integrated at the single-copy tmRNA gene,...

journal_title：BMC genomics

authors： McMurdie PJ,Hug LA,Edwards EA,Holmes S,Spormann AM

更新日期：2011-06-02 00:00:00

abstract：BACKGROUND:The bulldog calf syndrome is a lethal form of the inherited congenital chondrodysplasias. Among the progeny of the polled Holstein bull Energy P cases of lethal chondrodysplasia were observed. Pedigrees of the cases and the frequency of 3/8 cases among the offspring of Energy P at our teaching and experiment...

journal_title：BMC genomics

authors： Reinartz S,Mohwinkel H,Sürie C,Hellige M,Feige K,Eikelberg D,Beineke A,Metzger J,Distl O

更新日期：2017-10-10 00:00:00

abstract：BACKGROUND:Phomopsis longicolla T. W. Hobbs (syn. Diaporthe longicolla) is a seed-borne fungus causing Phomopsis seed decay in soybean. This disease is one of the most devastating diseases reducing soybean seed quality worldwide. To facilitate investigation of the genomic basis of pathogenicity and to understand the me...

journal_title：BMC genomics

authors： Li S,Darwish O,Alkharouf NW,Musungu B,Matthews BF

更新日期：2017-09-05 00:00:00

abstract：BACKGROUND:Loaches of Cobitinae, widely distributed in Eurasian continent, have high economic, ornamental and scientific value. However, the phylogeny of Cobitinae fishes within genera or family level remains complex and controversial. Up to now, about 60 Cobitinae mitogenomes had been deposited in GenBank, but their i...

journal_title：BMC genomics

authors： Yu P,Zhou L,Yang WT,Miao LJ,Li Z,Zhang XJ,Wang Y,Gui JF

更新日期：2021-01-14 00:00:00