Re-evaluation of the role of Indian germplasm as center of melon diversification based on genotyping-by-sequencing analysis.

abstract：BACKGROUND:Complete or near-complete genomic sequence information is presently only available for a few plant species representing a large phylogenetic diversity among plants. In order to effectively transfer this information to species lacking sequence information, comparative genomic tools need to be developed. Molec...

journal_title：BMC genomics

authors： Fredslund J,Madsen LH,Hougaard BK,Nielsen AM,Bertioli D,Sandal N,Stougaard J,Schauser L

更新日期：2006-08-14 00:00:00

abstract：BACKGROUND:The development of microarrays permits us to monitor transcriptomes on a genome-wide scale. To validate microarray measurements, quantitative-real time-reverse transcription PCR (Q-RT-PCR) is one of the most robust and commonly used approaches. The new challenge in gene quantification analysis is how to expl...

journal_title：BMC genomics

authors： Su LJ,Chang CW,Wu YC,Chen KC,Lin CJ,Liang SC,Lin CH,Whang-Peng J,Hsu SL,Chen CH,Huang CY

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:As an important nosocomial pathogen, Enterococcus faecium has received increasing attention in recent years. However, a large number of studies have focused on the hospital-associated isolates and ignored isolates originated from the natural environments. RESULTS:In this study, comparative genomic analysis ...

journal_title：BMC genomics

authors： Zhong Z,Kwok LY,Hou Q,Sun Y,Li W,Zhang H,Sun Z

更新日期：2019-07-22 00:00:00

abstract：BACKGROUND:With its genome sequence and other experimental attributes, Populus trichocarpa has become the model species for genomic studies of wood development. Wood is derived from secondary growth of tree stems, and begins with the development of a ring of vascular cambium in the young developing stem. The terminal r...

journal_title：BMC genomics

authors： Dharmawardhana P,Brunner AM,Strauss SH

更新日期：2010-03-04 00:00:00

abstract：BACKGROUND:Sand fly saliva plays an important role in blood feeding and Leishmania transmission as it was shown to increase parasite virulence. On the other hand, immunity to salivary components impedes the establishment of infection. Therefore, it is most desirable to gain a deeper insight into the composition of sali...

journal_title：BMC genomics

authors： Hostomská J,Volfová V,Mu J,Garfield M,Rohousová I,Volf P,Valenzuela JG,Jochim RC

更新日期：2009-06-25 00:00:00

abstract：BACKGROUND:Synthetic systems that use positive feedback have been developed to control human disease vectors and crop pests. The tTAV system, which has been deployed in several insect species, relies on a positive feedback circuit that can be inhibited via dietary tetracycline. Although insects carrying tTAV fail to su...

journal_title：BMC genomics

authors： Bryk J,Reeves RG,Reed FA,Denton JA

更新日期：2017-12-28 00:00:00

abstract：BACKGROUND:Higher crustaceans (class Malacostraca) represent the most species-rich and morphologically diverse group of non-insect arthropods and many of its members are commercially important. Although the crustacean DNA sequence information is growing exponentially, little is known about the genome organization of Ma...

journal_title：BMC genomics

authors： Koyama T,Asakawa S,Katagiri T,Shimizu A,Fagutao FF,Mavichak R,Santos MD,Fuji K,Sakamoto T,Kitakado T,Kondo H,Shimizu N,Aoki T,Hirono I

更新日期：2010-02-26 00:00:00

abstract：BACKGROUND:Much of the morphological diversity in eukaryotes results from differential regulation of gene expression in which transcription factors (TFs) play a central role. The nematode Caenorhabditis elegans is an established model organism for the study of the roles of TFs in controlling the spatiotemporal pattern ...

journal_title：BMC genomics

authors： Haerty W,Artieri C,Khezri N,Singh RS,Gupta BP

更新日期：2008-08-27 00:00:00

abstract：BACKGROUND:Myostatin, a muscle-specific member of the Transforming Growth Factor beta family, negatively regulates muscle development. Double-muscled (DM) cattle have a loss-of-function mutation in their myostatin gene responsible for the hypermuscular phenotype. Thus, these animals are a good model for understanding t...

journal_title：BMC genomics

authors： Cassar-Malek I,Passelaigue F,Bernard C,Léger J,Hocquette JF

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Gene expression variation is a key underlying factor influencing phenotypic variation, and can occur via cis- or trans-regulation. To understand the role of cis- and trans-regulatory variation on population divergence in chicken, we developed reciprocal crosses of two chicken breeds, White Leghorn and Cornis...

journal_title：BMC genomics

authors： Wang Q,Jia Y,Wang Y,Jiang Z,Zhou X,Zhang Z,Nie C,Li J,Yang N,Qu L

更新日期：2019-12-05 00:00:00

abstract：BACKGROUND:The Xklp2 (TPX2) proteins belong to the microtubule-associated (MAP) family of proteins. All members of the family contain the conserved TPX2 motif, which can interact with microtubules, regulate microtubule dynamics or assist with different microtubule functions, for example, maintenance of cell morphology ...

journal_title：BMC genomics

authors： Du P,Kumar M,Yao Y,Xie Q,Wang J,Zhang B,Gan S,Wang Y,Wu AM

更新日期：2016-11-24 00:00:00

abstract：BACKGROUND:Serine/threonine kinase 33 (STK33) has been shown to be conserved across all major vertebrate classes including reptiles, mammals, amphibians and fish, suggesting its importance within vertebrates. It has been shown to phosphorylate vimentin and might play a role in spermatogenesis and organ ontogenesis. In ...

journal_title：BMC genomics

authors： Lautwein T,Lerch S,Schäfer D,Schmidt ER

更新日期：2015-07-22 00:00:00

abstract：BACKGROUND:Ramularia collo-cygni is a newly important, foliar fungal pathogen of barley that causes the disease Ramularia leaf spot. The fungus exhibits a prolonged endophytic growth stage before switching life habit to become an aggressive, necrotrophic pathogen that causes significant losses to green leaf area and he...

journal_title：BMC genomics

authors： McGrann GR,Andongabo A,Sjökvist E,Trivedi U,Dussart F,Kaczmarek M,Mackenzie A,Fountaine JM,Taylor JM,Paterson LJ,Gorniak K,Burnett F,Kanyuka K,Hammond-Kosack KE,Rudd JJ,Blaxter M,Havis ND

更新日期：2016-08-09 00:00:00

abstract：BACKGROUND:The Engrailed Homology 1 (EH1) motif is a small region, believed to have evolved convergently in homeobox and forkhead containing proteins, that interacts with the Drosophila protein groucho (C. elegans unc-37, Human Transducin-like Enhancers of Split). The small size of the motif makes its reliable identifi...

journal_title：BMC genomics

authors： Copley RR

更新日期：2005-11-27 00:00:00

abstract：BACKGROUND:Pekin duck products have become popular in Asia over recent decades and account for an increasing market share. However, the genetic mechanisms affecting carcass growth in Pekin ducks remain unknown. This study aimed to identify quantitative trait loci affecting body size and carcass yields in Pekin ducks. ...

journal_title：BMC genomics

authors： Deng MT,Zhu F,Yang YZ,Yang FX,Hao JP,Chen SR,Hou ZC

更新日期：2019-01-03 00:00:00

abstract：BACKGROUND:Iron homeostasis is a key metabolism for most organisms. In many bacterial species, coordinate regulation of iron homeostasis depends on the protein product of a Fur gene. Fur also plays roles in virulence, acid tolerance, redox-stress responses, flagella chemotaxis and metabolic pathways. RESULTS:We conduc...

journal_title：BMC genomics

authors： Yang Y,Harris DP,Luo F,Wu L,Parsons AB,Palumbo AV,Zhou J

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Variation in gene expression between two Drosophila melanogaster strains, as revealed by transcriptional profiling, seldom corresponded to variation in proximal promoter sequence for 34 genes analyzed. Two sets of protein-coding genes were selected from pre-existing microarray data: (1) those whose expressio...

journal_title：BMC genomics

authors： Brown RP,Feder ME

更新日期：2005-08-17 00:00:00

abstract：BACKGROUND:Rapid acquisition of accurate genotyping information is essential for all genetic marker-based studies. For species with relatively small genomes, complete genome resequencing is a feasible approach for genotyping; however, for species with large and highly repetitive genomes, the acquisition of whole genome...

journal_title：BMC genomics

authors： Morishige DT,Klein PE,Hilley JL,Sahraeian SM,Sharma A,Mullet JE

更新日期：2013-07-05 00:00:00

abstract：BACKGROUND:Because of the advent of high-throughput sequencing and the consequent reduction in the cost of sequencing, many organisms have been completely sequenced and most of their genes identified. It thus has become possible to represent whole genomes as ordered lists of gene identifiers and to study the rearrangem...

journal_title：BMC genomics

authors： Yue F,Zhang M,Tang J

更新日期：2008-09-16 00:00:00

abstract：BACKGROUND:Copy number variations (CNVs) are a major form of genetic variations and are involved in animal domestication and genetic adaptation to local environments. We investigated CNVs in the domestic goat (Capra hircus) using Illumina short-read sequencing data, by comparing our lab data for 38 goats from three Chi...

journal_title：BMC genomics

authors： Guo J,Zhong J,Liu GE,Yang L,Li L,Chen G,Song T,Zhang H

更新日期：2020-11-27 00:00:00

abstract：BACKGROUND:Chronic renal disease (CKD) is characterized by complex changes in cell metabolism leading to an increased production of oxygen radicals, that, in turn has been suggested to play a key role in numerous clinical complications of this pathological condition. Several reports have focused on the identification o...

journal_title：BMC genomics

authors： Granata S,Zaza G,Simone S,Villani G,Latorre D,Pontrelli P,Carella M,Schena FP,Grandaliano G,Pertosa G

更新日期：2009-08-21 00:00:00

abstract：BACKGROUND:Precision medicine is a medical approach that takes into account individual genetic variability and often requires Next Generation Sequencing data in order to predict new treatments. Here we present GMIEC, Genomic Modules Identification et Characterization for genomics medicine, an application that is able t...

journal_title：BMC genomics

authors： Malagoli Tagliazucchi G,Taccioli C

更新日期：2020-09-10 00:00:00

abstract：BACKGROUND:After several years in the juvenile phase, trees undergo flowering transition to become mature (florally competent) trees. This transition depends on the balanced expression of a complex network of genes that is regulated by both endogenous and environmental factors. However, relatively little is known about...

journal_title：BMC genomics

authors： Zhang JZ,Ai XY,Sun LM,Zhang DL,Guo WW,Deng XX,Hu CG

更新日期：2011-01-26 00:00:00

abstract：BACKGROUND:The SOS response is a well-known regulatory network present in most bacteria and aimed at addressing DNA damage. It has also been linked extensively to stress-induced mutagenesis, virulence and the emergence and dissemination of antibiotic resistance determinants. Recently, the SOS response has been shown to...

journal_title：BMC genomics

authors： Sanchez-Alberola N,Campoy S,Barbé J,Erill I

更新日期：2012-02-03 00:00:00

abstract：BACKGROUND:The Polima (pol) system of cytoplasmic male sterility (CMS) and its fertility restoration gene Rfp have been used in hybrid breeding in Brassica napus, which has greatly improved the yield of rapeseed. However, the mechanism of the male sterility transition in pol CMS remains to be determined. RESULTS:To in...

journal_title：BMC genomics

authors： An H,Yang Z,Yi B,Wen J,Shen J,Tu J,Ma C,Fu T

更新日期：2014-04-03 00:00:00

abstract：BACKGROUND:Reading disability (RD) is a common syndrome with a large genetic component. Chromosome 6 has been identified in several linkage studies as playing a significant role. A more recent study identified a peak of transmission disequilibrium to marker JA04 (G72384) on chromosome 6p22.3, suggesting that a gene is ...

journal_title：BMC genomics

authors： Londin ER,Meng H,Gruen JR

更新日期：2003-06-30 00:00:00

abstract：BACKGROUND:Second-generation sequencing technologies have revolutionized our ability to recover genetic information from the past, allowing the characterization of the first complete genomes from past individuals and extinct species. Recently, third generation Helicos sequencing platforms, which perform true Single-Mol...

journal_title：BMC genomics

authors： Ginolhac A,Vilstrup J,Stenderup J,Rasmussen M,Stiller M,Shapiro B,Zazula G,Froese D,Steinmann KE,Thompson JF,Al-Rasheid KA,Gilbert TM,Willerslev E,Orlando L

更新日期：2012-05-10 00:00:00

abstract：BACKGROUND:Using the piggyBac-mediated GAL4/UAS transgenic system established in the silkworm, Bombyx mori, we have previously reported that overexpression of the Ras1(CA) oncogene specifically in the posterior silk gland (PSG) improved cell growth, fibroin synthesis, and thus silk yield. However, the detailed molecula...

journal_title：BMC genomics

authors： Ma L,Ma Q,Li X,Cheng L,Li K,Li S

更新日期：2014-03-09 00:00:00

abstract：BACKGROUND:Tandem mass spectrometry (MS/MS) has become a standard method for identification of proteins extracted from biological samples but the huge number and the noise contamination of MS/MS spectra obstruct swift and reliable computer-aided interpretation. Typically, a minor fraction of the spectra per sample (mos...

journal_title：BMC genomics

authors： Mujezinovic N,Schneider G,Wildpaner M,Mechtler K,Eisenhaber F

更新日期：2010-02-10 00:00:00

abstract：BACKGROUND:Toxin-antitoxin (TA) systems, abundant in prokaryotes, are composed of a toxin gene and its cognate antitoxin. Several toxins are implied to affect the physiological state and stress tolerance of bacteria in a population. We previously identified a chromosomally encoded hok-sok type I TA system in Erwinia am...

journal_title：BMC genomics

authors： Peng J,Triplett LR,Sundin GW

更新日期：2021-01-22 00:00:00