Abstract:
:We report a case of polycythemia vera with chorea in which the brain metabolism and dopamine system were investigated using 2-[(18)F]fluoro-2-deoxy-D-glucose positron emission tomography (FDG PET) and (99m)Tc-labeled tropane dopamine transporter ((99m)Tc-TRODAT-1) single photon emission computed tomography (SPECT). Along with normalization of the hematocrit and clinical symptoms after consecutive phlebotomies, the FDG PET scan and (99m)Tc-TRODAT-1 SPECT images returned towards normal. It is hypothesized that the development of polycythemia chorea is associated with a reversible alteration in the corticobasal ganglia metabolism and disturbed dopaminergic function.
journal_name
J Neuroljournal_title
Journal of neurologyauthors
Huang HC,Wu YC,Shih LY,Lo WC,Tsai CH,Shyu WCdoi
10.1007/s00415-011-6069-ysubject
Has Abstractpub_date
2011-11-01 00:00:00pages
2054-7issue
11eissn
0340-5354issn
1432-1459journal_volume
258pub_type
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