Abstract:
PURPOSE:To determine prescribing patterns by general physicians working in primary care (GPs) in Iran for the elderly and the prevalence of inappropriate prescribing. METHODS:We collected information about prescribed medicines for 10% of patients in primary care aged 65 years or above in six cities in one province during two separate months 1 year apart. Inappropriate prescribing was determined using Beers criteria, excluding diagnosis-related medications. The WHO indicators for appropriateness of prescribing in general practice and drug-drug interactions (DDIs) were also assessed. RESULTS:A total of 2041 patients were studied (mean age 73 years, 56% were women). Drugs for the alimentary system (20%), nervous system (15%), cardiovascular system (14%), and anti-infectives (12%) were most frequently prescribed. Almost all drugs (96%) were prescribed by generic names. Thirty percent of patients received at least one inappropriate drug (27% for men; 33% for women), whereof 94% were categorized as high risk for adverse effects. Indomethacin, diphenhydramine, and methocarbamol were the most common inappropriate medications. The average number of drugs per patient was 4.4 (4.2 for men; 4.5 for women). Forty-four percent of patients received five or more drugs. Antibiotics and injections were prescribed in 39 and 55% of all patients, respectively. Clinically relevant DDIs were observed for 14% of the patients. CONCLUSION:Our findings call for further interventions aiming at educating GPs to reduce potential errors. National drug policies and prescribing guidelines should be implemented to address the problem of inappropriate drug usage among the elderly.
journal_name
Pharmacoepidemiol Drug Safjournal_title
Pharmacoepidemiology and drug safetyauthors
Ghadimi H,Esmaily HM,Wahlstrom Rdoi
10.1002/pds.2106subject
Has Abstractpub_date
2011-05-01 00:00:00pages
482-7issue
5eissn
1053-8569issn
1099-1557journal_volume
20pub_type
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journal_title:Pharmacoepidemiology and drug safety
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doi:10.1002/pds.3984
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journal_title:Pharmacoepidemiology and drug safety
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doi:10.1002/pds.1695
更新日期:2009-02-01 00:00:00
abstract::Intravenous immunoglobulins (i.v.IG) are increasingly used in various clinical situations for which they have been considered to be safe and effective. However, since 1987, some cases of renal toxicity have been reported. Forty-nine cases of acute renal failure have been notified to the French Regional Pharmacovigilan...
journal_title:Pharmacoepidemiology and drug safety
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journal_title:Pharmacoepidemiology and drug safety
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journal_title:Pharmacoepidemiology and drug safety
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期:2005-04-01 00:00:00
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journal_title:Pharmacoepidemiology and drug safety
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doi:10.1002/pds.646
更新日期:2001-12-01 00:00:00
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pub_type: 杂志文章
doi:10.1002/pds.5136
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更新日期:2017-11-01 00:00:00
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doi:10.1002/pds.886
更新日期:2004-03-01 00:00:00
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更新日期:2020-03-01 00:00:00
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journal_title:Pharmacoepidemiology and drug safety
pub_type: 杂志文章
doi:10.1002/pds.1708
更新日期:2009-03-01 00:00:00
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journal_title:Pharmacoepidemiology and drug safety
pub_type: 杂志文章
doi:10.1002/(SICI)1099-1557(199807/08)7:4<275::AID-PDS
更新日期:1998-07-01 00:00:00
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pub_type: 杂志文章
doi:10.1002/pds.2133
更新日期:2011-06-01 00:00:00
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doi:10.1002/pds.955
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pub_type: 杂志文章
doi:10.1002/pds.1554
更新日期:2008-03-01 00:00:00
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pub_type: 杂志文章
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更新日期:2003-07-01 00:00:00
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journal_title:Pharmacoepidemiology and drug safety
pub_type: 杂志文章
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更新日期:2001-08-01 00:00:00
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journal_title:Pharmacoepidemiology and drug safety
pub_type: 杂志文章,评审
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更新日期:2009-06-01 00:00:00
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journal_title:Pharmacoepidemiology and drug safety
pub_type: 杂志文章
doi:10.1002/pds.721
更新日期:2002-07-01 00:00:00
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journal_title:Pharmacoepidemiology and drug safety
pub_type: 杂志文章
doi:10.1002/pds.1151
更新日期:2006-03-01 00:00:00
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journal_title:Pharmacoepidemiology and drug safety
pub_type: 杂志文章
doi:10.1002/pds.699
更新日期:2002-06-01 00:00:00
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journal_title:Pharmacoepidemiology and drug safety
pub_type: 杂志文章,多中心研究
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更新日期:2015-03-01 00:00:00
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journal_title:Pharmacoepidemiology and drug safety
pub_type: 杂志文章
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更新日期:2005-08-01 00:00:00
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journal_title:Pharmacoepidemiology and drug safety
pub_type: 杂志文章
doi:10.1002/(SICI)1099-1557(199907)8:4<275::AID-PDS427
更新日期:1999-07-01 00:00:00
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pub_type: 杂志文章
doi:10.1002/pds.1805
更新日期:2009-10-01 00:00:00