Prescription patterns of antiepileptic drugs in young women: development of a tool to distinguish between epilepsy and psychiatric disorders.

abstract：PURPOSE:Three recent observational studies reported that the risk of fatal overdose is greater with venlafaxine than SSRI use. It is not clear whether patient factors could account for this finding. We evaluated whether risk factors for suicide are more prevalent among patients prescribed venlafaxine than patients pres...

journal_title：Pharmacoepidemiology and drug safety

authors： Mines D,Hill D,Yu H,Novelli L

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:European Surveillance of Congenital Anomalies (EUROCAT) is a network of population-based congenital anomaly registries in Europe surveying more than 1 million births per year, or 25% of the births in the European Union. This paper describes the potential of the EUROCAT collaboration for pharmacoepidemiology ...

journal_title：Pharmacoepidemiology and drug safety

authors： Meijer WM,Cornel MC,Dolk H,de Walle HE,Armstrong NC,de Jong-van den Berg LT,EUROCAT Working Group.

更新日期：2006-09-01 00:00:00

abstract：:The UK Drug Utilization Research Group's (DURG) Regional Meeting 'New Horizons: Pharmacovigilance' was hosted by the Drug Safety Research Unit (DSRU) at Southampton on 19 May 2000. Opening the meeting, Dr Keith Beard, UK DURG chairman, welcomed delegates and speakers and thanked the DSRU team for hosting the meeting. ...

journal_title：Pharmacoepidemiology and drug safety

authors： Barnes J

更新日期：2000-09-01 00:00:00

abstract：PURPOSE:Our aim was to describe and assess the medicinal products and doses used for euthanasia in a series of cases, identified within an epidemiological death certificate study in Belgium, where euthanasia was until recently legally forbidden and where guidelines for euthanasia are not available. METHODS:In a random...

journal_title：Pharmacoepidemiology and drug safety

authors： Vander Stichele RH,Bilsen JJ,Bernheim JL,Mortier F,Deliens L

更新日期：2004-02-01 00:00:00

abstract：PURPOSE:This study evaluated the safety of oseltamivir during the 2009 influenza pandemic. METHODS:Case reports were obtained from the Roche safety database. The incidence of adverse events (AEs) during the pandemic (1 May 2009 to 31 December 2009) was compared with that beforehand (during previous influenza seasons) ...

journal_title：Pharmacoepidemiology and drug safety

authors： Donner B,Bader-Weder S,Schwarz R,Peng MM,Smith JR,Niranjan V

更新日期：2011-05-01 00:00:00

abstract：PURPOSE:We use simulations and an empirical example to evaluate the performance of disease risk score (DRS) matching compared with propensity score (PS) matching when controlling large numbers of covariates in settings involving newly introduced treatments. METHODS:We simulated a dichotomous treatment, a dichotomous o...

journal_title：Pharmacoepidemiology and drug safety

authors： Wyss R,Ellis AR,Brookhart MA,Jonsson Funk M,Girman CJ,Simpson RJ Jr,Stürmer T

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:To describe a bias that can occur in the analysis of data from certain randomized trials. METHODS AND RESULTS:Although randomized trials are effective at preventing confounding, a potentially strong confounding can arise in certain therapeutic drug trials in which follow-up is extended in an open-label phase t...

journal_title：Pharmacoepidemiology and drug safety

authors： Rothman KJ

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Cause of death is often not available in administrative claims data. OBJECTIVE:To develop claims-based algorithms to identify deaths due to fatal cardiovascular disease (CVD; ie, fatal coronary heart disease [CHD] or stroke), CHD, and stroke. METHODS:Reasons for Geographic and Racial Differences in Stroke ...

journal_title：Pharmacoepidemiology and drug safety

authors： Xie F,Colantonio LD,Curtis JR,Kilgore ML,Levitan EB,Monda KL,Safford MM,Taylor B,Woodward M,Muntner P

更新日期：2018-07-01 00:00:00

abstract：PURPOSE:In epidemiological studies, non-response may introduce bias and limit generalizability. In genetic pharmacoepidemiological research, collection of DNA might be a major reason for non-response. We determined reasons for non-response and compared characteristics of non-responders and responders in a pharmacogenet...

journal_title：Pharmacoepidemiology and drug safety

authors： van Wieren-de Wijer DB,Maitland-van der Zee AH,de Boer A,Kroon AA,de Leeuw PW,Schiffers P,Janssen RG,Psaty BM,van Duijn CM,Stricker BH,Klungel OH

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to generate data regarding the drug utilization pattern in pediatric population of our tertiary care hospital so that we could generate an essential medicine list (EML). BACKGROUND:Drug therapy accounts for a major portion of expenditure toward health care. Reduction in health ...

journal_title：Pharmacoepidemiology and drug safety

authors： Singh I,Mittal R,Shafiq N,Bharati B,Nigah RK,Pandhi P,Chaudhary RR,Malhotra S

更新日期：2010-04-01 00:00:00

abstract：PURPOSE:Stimulant medications used for treating attention deficit hyperactivity disorder (ADHD) can be associated with an increased risk of seizures. Atomoxetine is a non-stimulant medication approved for treating ADHD. This retrospective cohort analysis evaluated risk of seizures among pediatric patients naïve to ADHD...

journal_title：Pharmacoepidemiology and drug safety

authors： McAfee AT,Landon J,Jones M,Bangs ME,Acharya N,Hornbuckle K,Wong J

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:We evaluated national outpatient antimicrobial prescription trends in relation to the first United States case of inhalational anthrax due to the intentional delivery of Bacillus anthracis (B. anthracis) spores. METHODS:We queried IMS HEALTH's National Prescription Audit Plus7 database for two 6-month periods ...

journal_title：Pharmacoepidemiology and drug safety

authors： Shaffer D,Armstrong G,Higgins K,Honig P,Coyne P,Boxwell D,Beitz J,Leissa B,Murphy D

更新日期：2003-04-01 00:00:00

abstract：PURPOSE:Evidence is growing that early use of disease-modifying anti-rheumatic drugs (DMARDs) and combinations of these drugs provide optimal care for people with rheumatoid arthirits. The aim of this study was to describe objectively the pattern of consumption of DMARDs in the Australian community (community-based pre...

journal_title：Pharmacoepidemiology and drug safety

authors： Chan V,Tett SE

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Current methods for prospective drug safety monitoring focus on determining whether and when to generate safety alerts indicating that a new drug may be less safe than a comparator. Approaches are needed to develop safety thresholds that can be used to define whether a new drug is no less than or equally saf...

journal_title：Pharmacoepidemiology and drug safety

authors： Wangge G,Schneeweiss S,Glynn RJ,Gagne JJ

更新日期：2016-07-01 00:00:00

abstract：:Schizophrenia is a life-threatening disease associated with mortality rates that are two to three times higher than those expected/observed in the general population. It is associated with high levels of suicide, particularly in young male patients soon after diagnosis. Delays in treating schizophrenia could contribut...

journal_title：Pharmacoepidemiology and drug safety

authors： Auquier P,Lançon C,Rouillon F,Lader M

更新日期：2007-12-01 00:00:00

abstract：PURPOSE:Breast cancer is the most common cancer in women worldwide. We attempted to investigate the association between the risk of breast cancer and use of captopril and other antihypertensive medication. METHODS:We performed a cohort study with a nested case-control analysis using the General Practitioner Research D...

journal_title：Pharmacoepidemiology and drug safety

authors： González-Pérez A,Ronquist G,García Rodríguez LA

更新日期：2004-08-01 00:00:00

abstract：PURPOSE:To identify and quantify risk factors associated with preterm birth, stratified by gestational age at birth. METHODS:Three case-control analyses were done. Controls were pregnancies of > or =37 weeks of gestational age at birth. Cases were defined as: <28, 28-32, 33- <37 weeks of gestational age at birth respe...

journal_title：Pharmacoepidemiology and drug safety

authors： Ofori BD,Le Tiec M,Bérard A

更新日期：2008-06-01 00:00:00

abstract：PURPOSE:To assess the feasibility of using Clinical Practice Research Datalink (CPRD) data for identifying populations of patients with chronic obstructive pulmonary disease (COPD) eligible for a hypothetical pragmatic trial. METHODS:A retrospective multidatabase cohort study using CPRD primary care and linked seconda...

journal_title：Pharmacoepidemiology and drug safety

authors： Requena G,Wolf A,Williams R,Dedman D,Quint JK,Murray-Thomas T,Pimenta JM

更新日期：2020-12-27 00:00:00

abstract：PURPOSE:To assess the prevalence of adverse drug reactions (ADRs) occurring in patients with Alzheimer's disease (AD) or other dementia in France. METHODS:A cross-sectional multicentre study was conducted by the French network of the 31 regional pharmacovigilance centres on a given day. The subjects were selected by r...

journal_title：Pharmacoepidemiology and drug safety

authors： Laroche ML,Perault-Pochat MC,Ingrand I,Merle L,Kreft-Jais C,Castot-Villepelet A,Durrieu G,Gras V,Guy C,Jean-Pastor MJ,Jonville-Béra AP,Merlet-Chicoine I,Miremont-Salamé G,Nourhashemi F,Charmes JP,French Centres of Pharmacov

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:To compare birth outcomes between women exposed and unexposed to the antiviral medications oseltamivir or zanamivir during pregnancy. METHODS:This was an observational cohort study including women who gave birth to singletons in Sweden 2005-2007 and their infants. We obtained information from the national heal...

journal_title：Pharmacoepidemiology and drug safety

authors： Svensson T,Granath F,Stephansson O,Kieler H

更新日期：2011-10-01 00:00:00

abstract：PURPOSE:Our objective was to examine the numbers and characteristics of US pediatric adverse events (AEs) reported to the Food and Drug Administration (FDA)'s adverse event reporting system (AERS) for 5 years following implementation of the Best Pharmaceuticals for Children Act (BPCA) in 2002. METHODS:We analyzed repo...

journal_title：Pharmacoepidemiology and drug safety

authors： Johann-Liang R,Wyeth J,Chen M,Cope JU

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:First-in-class (FIC) drugs with novel modes of action pose concerns regarding important postmarketing safety issues. The purpose of this study was to analyze the factors related to the occurrence of postmarketing safety-related regulatory actions (PSRAs) for drugs approved in the United States (US), with a focu...

journal_title：Pharmacoepidemiology and drug safety

authors： Ikeda J,Kaneko M,Narukawa M

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:To report the use of direct oral anticoagulants (DOACs) for stroke prevention in patients with atrial fibrillation in Scotland and advocate the standardisation of drug utilisation research methods. METHODS:Retrospective cohort study using linked administrative data. Patients included those with a diagnosis of ...

journal_title：Pharmacoepidemiology and drug safety

authors： Mueller T,Alvarez-Madrazo S,Robertson C,Bennie M

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:We conducted a nested case-control study to evaluate the association between risk of cancer and mirtazapine use in depression patients in Taiwan. METHODS:We obtained data from the Taiwan National Health Insurance Research Database to conduct a population-based nested case-control study. The study cohort includ...

journal_title：Pharmacoepidemiology and drug safety

authors： Sun LM,Lin MC,Liang JA,Chang YJ,Chang SN,Sung FC,Muo CH,Kao CH

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:Patients initiating warfarin therapy generally experience a dose-titration period of weeks to months, during which time they are at higher risk of both thromboembolic and bleeding events. Accurate prediction of prolonged dose titration could help clinicians determine which patients might be better treated by al...

journal_title：Pharmacoepidemiology and drug safety

authors： Finkelman BS,French B,Bershaw L,Brensinger CM,Streiff MB,Epstein AE,Kimmel SE

更新日期：2016-11-01 00:00:00

abstract：:When a biological hypothesis of causal effect can be inferred, the hypothesis can sometimes be tested in the selfsame database that gave rise to the study data from which the hypothesis grew. Valid testing happens when the inferred biological hypothesis has scientific implications that predict new relations between ob...

journal_title：Pharmacoepidemiology and drug safety

authors： Walker AM

更新日期：2010-05-01 00:00:00

abstract：PURPOSE:Quantitative benefit-risk (B-R) assessments are used to characterize treatment by combining key benefits and risks into a single metric but have historically been done for the "average" patient. Our aim was to conduct an individualized assessment for the oral antiplatelet vorapaxar by combining trial and real-w...

journal_title：Pharmacoepidemiology and drug safety

authors： Pinto CA,Tervonen T,Marsh K,Lambrelli D,Schultze A,Tershakovec A,Hyacinthe J,Prawitz T,Hammad TA

更新日期：2019-04-01 00:00:00

abstract：:Analysing duration of treatment episodes has become a standard task in many pharmacoepidemiological studies. However, such analyses are often carried out in a rather simplistic manner and more subtle issues are often ignored. In this paper, methods of analysing duration treatment episodes beyond simple analyses allowi...

journal_title：Pharmacoepidemiology and drug safety

authors： Gichangi A,Andersen M,Kragstrup J,Vach W

更新日期：2006-03-01 00:00:00

abstract：PURPOSE:To measure changes in drug utilisation following a national general practice education program aimed at improving prescribing for hypertension. METHODS:A series of nationally implemented, multifaceted educational interventions using social marketing principles focusing on prescribing for hypertension, was comm...

journal_title：Pharmacoepidemiology and drug safety

authors： Horn FE,Mandryk JA,Mackson JM,Wutzke SE,Weekes LM,Hyndman RJ

更新日期：2007-03-01 00:00:00

abstract：PURPOSE:Nonsteroidal anti-inflammatory drugs (NSAIDs) may be associated with severe renal complications, including acute renal failure, reduced glomerular filtration rate and interstitial nephritis. Caution against NSAIDs is therefore recommended in advanced chronic kidney disease. In this study, we examined NSAID use,...

journal_title：Pharmacoepidemiology and drug safety

authors： Kristensen SL,Fosbøl EL,Kamper AL,Køber L,Hommel K,Lamberts M,Abildstrøm SZ,Blicher TM,Torp-Pedersen C,Gislason GH

更新日期：2012-04-01 00:00:00