Rostroventral medulla-mediated biphasic modulation of the rat cardiosomatic motor reflex.

abstract：:Mature neurons contain two distinct regulated secretory pathways, characterized electron microscopically by so-called large dense core vesicles and small synaptic vesicles, respectively. Each vesicle type is characterized by vesicle-specific proteins, such as the granins (chromogranins/secretogranins) for the matrix o...

journal_title：Neuroscience

authors： Tixier-Vidal A,Barret A,Faivre-Bauman A,Huttner W,Wiedenmann B

更新日期：1992-01-01 00:00:00

abstract：:The development of the catecholaminergic system in the hypothalamus and in the septal region was studied in rats from the 12th fetal day until the 9th postnatal day. Catecholaminergic structures were visualized with pre-embedding immunocytochemistry using antiserum to tyrosine hydroxylase. An intensification of diamin...

journal_title：Neuroscience

authors： Ugrumov MV,Taxi J,Tixier-Vidal A,Thibault J,Mitskevich MS

更新日期：1989-01-01 00:00:00

abstract：:Stress during early development produces lasting effects on psychopathological outcomes. We analysed the impact of prior intermittent, physical stress (IPS) during early adolescence (PD 22-33) on anxiety-like behaviour of female rats in adulthood. After behavioural testing, we used immunohistochemistry for the 5-HT tr...

journal_title：Neuroscience

authors： Tao CS,Dhamija P,Booij L,Menard JL

更新日期：2017-11-19 00:00:00

abstract：:In the enteric nervous system, acetylcholine is the most common neurotransmitter to induce gastrointestinal smooth muscle contractions. Cholinergic signaling is mediated by muscarinic acetylcholine receptors on the surface of smooth muscle cells. Five different muscarinic receptor subtypes (M(1)-M(5)) have been identi...

journal_title：Neuroscience

authors： Iino S,Nojyo Y

更新日期：2006-01-01 00:00:00

abstract：:Changes in the distribution of 5-hydroxytryptamine-like immunoreactivity have been examined in enteric neurons at various times after microsurgical lesions of the enteric plexuses. In the myenteric plexus, varicose immunoreactive nerve fibres disappeared or were reduced in number in ganglia anal to an interruption of ...

journal_title：Neuroscience

authors： Furness JB,Costa M

更新日期：1982-02-01 00:00:00

abstract：:Within the dorsomedial hypothalamus (DMH), cholecystokinin (CCK) has been proposed to modulate neuropeptide Y (NPY) signaling to affect food intake. However, the neural circuitry underlying the actions of this CCK-NPY signaling system in the controls of food intake has yet to be determined. We sought to characterize t...

journal_title：Neuroscience

authors： Chen J,Scott KA,Zhao Z,Moran TH,Bi S

更新日期：2008-03-03 00:00:00

abstract：:The thoracolumbar and lumbosacral spinal cord contain respectively sympathetic and parasympathetic preganglionic neurons that supply the organs of the pelvis including the penis. These neurons are influenced by supraspinal information and receive aminergic projections from the brainstem. The presence of the alpha(1)- ...

journal_title：Neuroscience

authors： Yaïci ED,Rampin O,Calas A,Jestin A,McKenna KE,Leclerc P,Benoit G,Giuliano F

更新日期：2002-01-01 00:00:00

abstract：:The distribution of N-methyl-D-aspartate- (NMDA) and kainic acid- (KA) sensitive ionotropic glutamate receptors (iGluR) in the zebrafish olfactory bulb was assessed using an activity-dependent labeling method. Olfactory bulbs were incubated with an ion channel permeant probe, agmatine (AGB), and iGluR agonists in vitr...

journal_title：Neuroscience

authors： Edwards JG,Michel WC

更新日期：2003-01-01 00:00:00

abstract：:Ubiquitination is a post-translational modification that can dynamically alter the function, degradation and transport of a protein, as well as its interaction with other proteins, and activity of an enzyme. Dysfunctional ubiquitination is detrimental to normal cellular functions, and can result in severe diseases. Ov...

journal_title：Neuroscience

authors： Zhu J,Tsai NP

更新日期：2020-01-21 00:00:00

abstract：:Exercise reduces the risk of developing a number of neurological disorders and increases the efficiency of cellular energy production. However, overly strenuous exercise produces oxidative stress. Proper oxygenation is crucial for the health of all tissues, and tight regulation of cellular oxygen is critical to balanc...

journal_title：Neuroscience

authors： Smeyne M,Sladen P,Jiao Y,Dragatsis I,Smeyne RJ

更新日期：2015-06-04 00:00:00

abstract：:Gambierol is a marine polycyclic ether toxin, first isolated from cultured Gambierdiscus toxicus dinoflagellates collected in French Polynesia. The chemical synthesis of gambierol permitted the analyses of its mode of action which includes the selective inhibition of voltage-gated K+ (KV) channels. In the present stud...

journal_title：Neuroscience

authors： Molgó J,Schlumberger S,Sasaki M,Fuwa H,Louzao MC,Botana LM,Servent D,Benoit E

更新日期：2020-07-15 00:00:00

abstract：:The aim of the present study was to examine the modification of postural symmetry during quiet standing using a sensorimotor adaptation paradigm. A group of neurologically typical adult participants performed a visually guided mediolateral (left-right) weight shifting task requiring precise adjustments in body orienta...

journal_title：Neuroscience

authors： Shiller DM,Veilleux LN,Marois M,Ballaz L,Lemay M

更新日期：2017-07-25 00:00:00

abstract：:The beta-amyloid precursor protein is the precursor of the main component of senile plaques (the beta-amyloid peptide or beta/A4) found in the brain of aged humans and, in higher amounts, in the brain of Alzheimer's disease and Down's syndrome subjects. Four different forms of beta-amyloid precursor protein messenger ...

journal_title：Neuroscience

authors： Solà C,Mengod G,Probst A,Palacios JM

更新日期：1993-03-01 00:00:00

abstract：:The vertebrate blood-brain barrier (BBB) creates an obstacle for central nervous system-related drug delivery. Claudin-5 (Cldn5), expressed in large quantities in BBB, plays a vital role in restricting BBB permeability. The C-terminal domain of Clostridium perfringens enterotoxin (cCPE) has been verified as binding to...

journal_title：Neuroscience

authors： Liao Z,Yang Z,Piontek A,Eichner M,Krause G,Li L,Piontek J,Zhang J

更新日期：2016-07-07 00:00:00

abstract：:Amphetamine induces a pronounced rotation directed ipsilateral to the lesion and lasting about 2 h in rats bearing a unilateral lesion of the nigrostriatal dopaminergic pathway. Implantation of embryonic dopaminergic neurons into the lesioned striatum leads to a compensation of this rotation. However, graft-bearing an...

journal_title：Neuroscience

authors： Herman JP,Rouge-Pont F,Le Moal M,Abrous DN

更新日期：1993-04-01 00:00:00

abstract：:A delayed-matching spatial working memory protocol in a 5-arm maze was used to test the hypothesis of differential roles for central nicotinic and muscarinic cholinergic receptors in mediating task performance. In experiment 1, using a within subjects-repeated design, groups of C57Bl/6 mice, previously trained to crit...

journal_title：Neuroscience

authors： Maviel T,Durkin TP

更新日期：2003-01-01 00:00:00

abstract：:This study was performed using intracellular and multiunit extracellular recording techniques in order to characterize the role of nitric oxide in the afferent synaptic transmission of the vestibular system of the axolotl (Ambystoma tigrinum). Bath application of nitric oxide synthase inhibitors N(G)-nitro-L-arginine ...

journal_title：Neuroscience

authors： Flores A,Soto E,Vega R

更新日期：2001-01-01 00:00:00

abstract：:In a natural acoustic environment, sound stimuli often occur in a contextual acoustic stream. The aim of the present study was to determine how the frequency tuning of auditory cortical neurons is affected by an acoustic context. A forward masking paradigm was used to determine the frequency receptive fields of rat au...

journal_title：Neuroscience

authors： Peng Y,Sun X,Zhang J

更新日期：2010-09-01 00:00:00

abstract：:In rats under urethane anaesthesia gamma-aminobutyric acid agonists and uptake blockers were microiontophoretically applied in the pyramidal layer of CA1 and in the apical dendrites using a twin set of multibarrelled micropipettes. Thus, the somatic and dendritic field potentials elicited by commissural stimulation we...

journal_title：Neuroscience

authors： Rovira C,Ben-Ari Y,Cherubini E

更新日期：1984-06-01 00:00:00

abstract：:Ascorbate is an antioxidant vitamin that is found in high concentrations in the brain which seems to have neuroprotective properties in some experimental models of excitotoxic neurological disorders, including convulsive behavior and reactive species-related damage. In this study we tested whether ascorbate (30, 100 o...

journal_title：Neuroscience

authors： Schneider Oliveira M,Flávia Furian A,Freire Royes LF,Rechia Fighera M,de Carvalho Myskiw J,Gindri Fiorenza N,Mello CF

更新日期：2004-01-01 00:00:00

abstract：:Hippocampal sclerosis is the most frequent pathology encountered in mesial temporal structures resected from patients with intractable temporal lobe epilepsy and it mainly involves hippocampal neuronal loss and gliosis. These alterations are accompanied by changes in the expression of a variety of molecules in the sur...

journal_title：Neuroscience

authors： Andrioli A,Alonso-Nanclares L,Arellano JI,DeFelipe J

更新日期：2007-10-12 00:00:00

abstract：:High-intensity sound can induce seizures in susceptible animals. After repeated acoustic stimuli changes in behavioural seizure repertoire and epileptic EEG activity might be seen in recruited limbic and forebrain structures, a phenomenon known as audiogenic kindling. It is postulated that audiogenic kindling can prod...

journal_title：Neuroscience

authors： Cunha AO,de Oliveira JA,Almeida SS,Garcia-Cairasco N,Leão RM

更新日期：2015-12-03 00:00:00

abstract：:Studies demonstrated that chronic high-dose homocysteine administration induced learning and memory impairment in animals. Atractylenolide III (Aen-III), a neuroprotective constituent of Atractylodis macrocephalae Koidz, was isolated in our previous study. In this study, we investigated potential benefits of Aen-III i...

journal_title：Neuroscience

authors： Zhao H,Ji ZH,Liu C,Yu XY

更新日期：2015-04-02 00:00:00

abstract：:Numerous epidemiological studies have shown an association between pesticide exposure and the increased risk of developing Parkinson's disease. Previously we have reported that Dichlorvos exposure can induce oxidative stress, resulting in over-expression of pro-apoptotic genes and finally caspase-dependent nigrostriat...

journal_title：Neuroscience

authors： Wani WY,Sunkaria A,Sharma DR,Kandimalla RJ,Kaushal A,Gerace E,Chiarugi A,Gill KD

更新日期：2014-01-31 00:00:00

abstract：:Stem cells have a number of properties, which make them excellent candidates for the treatment of various neurologic disorders, the most important of which being their ability to migrate to and differentiate predictably at sites of pathology in the brain. The disease-directed migration and well-characterized different...

journal_title：Neuroscience

authors： Carney BJ,Shah K

更新日期：2011-12-01 00:00:00

abstract：:In the present study the time-course of DNA fragmentation following insulin-induced hypoglycemia was examined. In situ localization of DNA breaks were studied by the terminal deoxynucleotidyl transferase-mediated biotin-deoxyuridine triphosphate nick-end labelling method, and the temporal profile of DNA-fragmentation ...

journal_title：Neuroscience

authors： Ferrand-Drake M,Friberg H,Wieloch T

更新日期：1999-01-01 00:00:00

abstract：:The dorsal pallidal complex is made up of the external and internal segments of the globus pallidus (GPe and GPi respectively). It is part of the main axis of the basal ganglia (BG) that connects the thalamo-cortical networks to the BG input stages (striatum and subthalamic nucleus) and continues directly, and indirec...

journal_title：Neuroscience

authors： Goldberg JA,Bergman H

更新日期：2011-12-15 00:00:00

abstract：:Dopamine (DA) axons and receptors have recently been identified in the primate thalamus, including the mediodorsal thalamic nucleus (MD). In order to determine whether the DA innervation of the primate MD shares the anatomical features of the mesocortical or nigrostriatal DA projections, we performed tract-tracing and...

journal_title：Neuroscience

authors： Melchitzky DS,Erickson SL,Lewis DA

更新日期：2006-12-28 00:00:00

abstract：:When the neural tracer Fluoro-Gold is used to retrogradely label a population of axotomized neurons, cellular labeling can persist in the axotomized nucleus even when Nissl staining indicates that the injured neurons have degenerated. In order to determine the identity of the labeled cells that remain, this study comb...

journal_title：Neuroscience

authors： Rinaman L,Milligan CE,Levitt P

更新日期：1991-01-01 00:00:00

abstract：:Brain bioenergetic abnormalities in mood disorders were detected by neuroimaging in vivo studies in humans. Because of the increasing importance of mitochondrial pathogenetic hypothesis of Depression, in this study the effects of sub-chronic treatment (21days) with desipramine (15mg/kg) and fluoxetine (10mg/kg) were e...

journal_title：Neuroscience

authors： Villa RF,Ferrari F,Gorini A,Brunello N,Tascedda F

更新日期：2016-08-25 00:00:00