Impact of daily temperature fluctuations on dengue virus transmission by Aedes aegypti.

abstract：:Despite their overall accuracy, errors in macromolecular processes, such as rRNA synthesis and ribosome assembly, inevitably occur. However, whether these errors are remediated and how this might be accomplished is not known. In previous work, we showed that a double mutant strain lacking both polynucleotide phosphory...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Cheng ZF,Deutscher MP

更新日期：2003-05-27 00:00:00

abstract：:All classes of antidepressants increase hippocampal cell proliferation and neurogenesis, which contributes, in part, to the behavioral actions of these treatments. Among antidepressant treatments, electroconvulsive seizure (ECS) is the most robust stimulator of hippocampal cell proliferation and the most efficacious t...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Segi-Nishida E,Warner-Schmidt JL,Duman RS

更新日期：2008-08-12 00:00:00

abstract：:Homologs of the chromatin-bound yeast silent information regulator 2 (SIR2) protein are found in organisms from all biological kingdoms. SIR2 itself was originally discovered to influence mating-type control in haploid cells by locus-specific transcriptional silencing. Since then, SIR2 and its homologs have been sugge...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Landry J,Sutton A,Tafrov ST,Heller RC,Stebbins J,Pillus L,Sternglanz R

更新日期：2000-05-23 00:00:00

abstract：:The principal methyl donor of the cell, S-adenosylmethionine (SAMe), is produced by the highly conserved family of methionine adenosyltranferases (MATs) via an ATP-driven process. These enzymes play an important role in the preservation of life, and their dysregulation has been tightly linked to liver and colon cancer...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Murray B,Antonyuk SV,Marina A,Lu SC,Mato JM,Hasnain SS,Rojas AL

更新日期：2016-02-23 00:00:00

abstract：:The concepts of source and quantum action principle are used to produce the phonon Green's function appropriate for an initial phonon vacuum state. An application to the Mossbauer effect is presented. ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Schwinger J

更新日期：1991-08-01 00:00:00

abstract：:Breast cancer remains the cancer with the highest mortality among women in the United States. Peptides derived from the oncogenic Tac1 gene (full transcript: betaPPT-A) stimulate the proliferation of breast cancer cells (BCCs) via seven-transmembrane G protein-coupled neurokinin 1 (NK1) and NK2 receptors. The NK1 gene...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Patel HJ,Ramkissoon SH,Patel PS,Rameshwar P

更新日期：2005-11-29 00:00:00

abstract：:A cylindrical detonating explosive behaves like a non-Newtonian viscous fluid emerging from a cylindrical pipe. The expression for non-Newtonian viscous flow has been applied to detonating explosives. The resultant fit to emerging flame fronts from detonation is excellent for a wide variety of detonating explosives bo...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Coon N,Ma SM,Redington PK,Brown B,Eyring H

更新日期：1980-10-01 00:00:00

abstract：:The partial amino acid sequences of human T-cell growth factors (TCGFs) isolated from normal peripheral blood lymphocytes and from a leukemia T-cell line (Jurkat) show that the amino-terminal sequences of the two proteins (15 residues) are identical. Oligonucleotides based on the published Jurkat TCGF DNA sequence wer...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Clark SC,Arya SK,Wong-Staal F,Matsumoto-Kobayashi M,Kay RM,Kaufman RJ,Brown EL,Shoemaker C,Copeland T,Oroszlan S

更新日期：1984-04-01 00:00:00

abstract：:A recently described organ culture system for human thymocytes is shown to support the generation of a diverse T-cell receptor repertoire in vitro: thymocytes of the alpha beta lineage, including representatives of the V beta families 5.2/5.3, 6.7, and 8, accounted for the majority of T-cell receptor-positive cells th...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Merkenschlager M,Fisher AG

更新日期：1992-05-15 00:00:00

abstract：:T-cell migration into tissue depends on a cascade of rapid and selective adhesive interactions with endothelium. "Triggering" is a step in that cascade required to activate T-cell integrins. Hepatocyte growth factor (HGF) may be a physiologically relevant trigger, since we demonstrate that HGF can induce both adhesion...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Adams DH,Harvath L,Bottaro DP,Interrante R,Catalano G,Tanaka Y,Strain A,Hubscher SG,Shaw S

更新日期：1994-07-19 00:00:00

abstract：:A debate has recently surfaced concerning the degree of precommitment attained by alpha beta and gamma delta T-cell precursors prior to T-cell receptor (TCR) gene rearrangement. It has been suggested that precursors may be precommitted to rearrange either alpha or delta genes, but not both, thus giving rise to alpha b...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Thompson SD,Pelkonen J,Hurwitz JL

更新日期：1990-07-01 00:00:00

abstract：:In skeletal muscle, dihydropyridine receptors are functionally coupled to ryanodine receptors of the sarcoplasmic reticulum in triadic or diadic junctional complexes. In cardiac muscle direct physical or functional couplings have not been demonstrated. We have tested the hypothesis of functional coupling of L-type Ca2...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Sham JS,Cleemann L,Morad M

更新日期：1995-01-03 00:00:00

abstract：:We analyzed a very large set of molecular interactions that had been derived automatically from biological texts. We found that published statements, regardless of their verity, tend to interfere with interpretation of the subsequent experiments and, therefore, can act as scientific "microparadigms," similar to domina...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Rzhetsky A,Iossifov I,Loh JM,White KP

更新日期：2006-03-28 00:00:00

abstract：:For almost a century the plant hormone auxin has been central to theories on apical dominance, whereby the growing shoot tip suppresses the growth of the axillary buds below. According to the classic model, the auxin indole-3-acetic acid is produced in the shoot tip and transported down the stem, where it inhibits bud...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Mason MG,Ross JJ,Babst BA,Wienclaw BN,Beveridge CA

更新日期：2014-04-22 00:00:00

abstract：:A patterning method termed "RIPPLE" (reactive interface patterning promoted by lithographic electrochemistry) is applied to the fabrication of arrays of dielectric and metallic optical elements. This method uses cyclic voltammetry to impart patterns onto the working electrode of a standard three-electrode electrochemi...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Kempa TJ,Bediako DK,Kim SK,Park HG,Nocera DG

更新日期：2015-04-28 00:00:00

abstract：:Results are reported showing that pituitary extracts stimulate growth of 3T3 cells, an established line of mouse fibroblast. Cells were cultured in medium containing an organic buffer (HEPES; N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid), which increases the serum requirement for cell growth. The pituitary grow...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Armelin HA

更新日期：1973-09-01 00:00:00

abstract：:The I-J subregion of the mouse major histocompatibility complex has been reported to encode antigenic determinants expressed by suppressor T cells. Previously, cosmid clones were obtained from mouse sperm DNA that contain all of the sequences between the I-A and I-E subregions, where I-J has been mapped genetically. H...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Kronenberg M,Steinmetz M,Kobori J,Kraig E,Kapp JA,Pierce CW,Sorensen CM,Suzuki G,Tada T,Hood L

更新日期：1983-09-01 00:00:00

abstract：:Transgenic sorghum plants have been obtained after microprojectile bombardment of immature zygotic embryos of a drought-resistant sorghum cultivar, P898012. DNA delivery parameters were optimized based on transient expression of R and C1 maize anthocyanin regulatory elements in scutellar cells. The protocol for obtain...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Casas AM,Kononowicz AK,Zehr UB,Tomes DT,Axtell JD,Butler LG,Bressan RA,Hasegawa PM

更新日期：1993-12-01 00:00:00

abstract：:The study of development has relied primarily on the isolation of mutations in genes with specific functions in development and on the comparison of their expression patterns in normal and mutant phenotypes. Comparative evolutionary analyses can complement these approaches. Phylogenetic analyses of Sonic hedgehog (Shh...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Zardoya R,Abouheif E,Meyer A

更新日期：1996-11-12 00:00:00

abstract：:A posttranslational protein O-mannosylation process resembling that found in fungi and animals has been reported in the major human pathogen Mycobacterium tuberculosis (Mtb) and related actinobacteria. However, the role and incidence of this process, which is essential in eukaryotes, have never been explored in Mtb. W...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Liu CF,Tonini L,Malaga W,Beau M,Stella A,Bouyssié D,Jackson MC,Nigou J,Puzo G,Guilhot C,Burlet-Schiltz O,Rivière M

更新日期：2013-04-16 00:00:00

abstract：:Preparations of partially purified chloroplast DNA-dependent RNA polymerase from maize and some other plants transcribe cloned chloroplast genes preferentially and much more actively from appropriately negatively supercoiled templates than from relaxed templates. We have found that the polymerase in such fractions doe...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Zaitlin D,Hu J,Bogorad L

更新日期：1989-02-01 00:00:00

abstract：:Using data from the North American Breeding Bird Survey, we determined that most neotropical migrant bird species that breed in forests of the eastern United States and Canada have recently (1978-1987) declined in abundance after a period of stable or increasing populations. Most permanent residents and temperate-zone...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Robbins CS,Sauer JR,Greenberg RS,Droege S

更新日期：1989-10-01 00:00:00

abstract：:Individuals homozygous for the C-C chemokine receptor type 5 gene with 32-bp deletions (CCR5Δ32) are resistant to HIV-1 infection. In this study, we generated induced pluripotent stem cells (iPSCs) homozygous for the naturally occurring CCR5Δ32 mutation through genome editing of wild-type iPSCs using a combination of ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Ye L,Wang J,Beyer AI,Teque F,Cradick TJ,Qi Z,Chang JC,Bao G,Muench MO,Yu J,Levy JA,Kan YW

更新日期：2014-07-01 00:00:00

abstract：:Communication about prescription drugs ought to be a paragon of public science communication. Unfortunately, it is not. Consumers see $4 billion of direct-to-consumer advertising annually, which typically fails to present data about how well drugs work. The professional label--the Food and Drug Administration's (FDA) ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Schwartz LM,Woloshin S

更新日期：2013-08-20 00:00:00

abstract：:An Epstein-Barr virus (EBV) deletion mutant, HR-1, cannot immortalize lymphocytes. HR-1 was derived from a virus strain, Jijoye, that is immortalization competent. Using human antiserum from certain patients with chronic active EBV infection, we have identified in Jijoye cells a protein of apparent mass of 78-80 kDa t...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Rowe D,Heston L,Metlay J,Miller G

更新日期：1985-11-01 00:00:00

abstract：:Heterochromatin protein 1 (HP1), first discovered in Drosophila melanogaster, is a highly conserved chromosomal protein implicated in both heterochromatin formation and gene silencing. We report here characterization of an HP1-interacting protein, heterochromatin protein 2 (HP2), which codistributes with HP1 in the pe...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Shaffer CD,Stephens GE,Thompson BA,Funches L,Bernat JA,Craig CA,Elgin SC

更新日期：2002-10-29 00:00:00

abstract：:An RNA-directed DNA polymerase was isolated from the peripheral blood leukocytes of a patient with acute myelomonocytic leukemia by successive purification of a particulate cytoplasmic fraction with endogenous, ribonuclease-sensitive DNA polymerase activity. Like RNA-directed DNA polymerase from mammalian type-C virus...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Gallagher RE,Todaro GJ,Smith RG,Livingston DM,Gallo RC

更新日期：1974-04-01 00:00:00

abstract：:Phytochrome is the photoreceptor that controls red light-mediated morphogenesis in higher plants. It exists in two photointerconvertible forms, a red light-absorbing form, Pr, and a far-red light-absorbing form, Pfr. Because photoconversion of Pr to Pfr by a brief light pulse decreases the in vivo half-life of this ch...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Shanklin J,Jabben M,Vierstra RD

更新日期：1987-01-01 00:00:00

abstract：:It has been shown that [35S]methionine is incorporated into the [Met]enkephalin sequences of a 22,000-dalton enkephalin-containing protein in the adrenal medulla. Pulse-chase experiments indicate that label is incorporated into the large polypeptide before it appears in free [Met]enkephalin and a smaller [Met]enkephal...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Rossier J,Trifaró JM,Lewis RV,Lee RW,Stern A,Kimura S,Stein S,Udenfriend S

更新日期：1980-11-01 00:00:00

abstract：:In virtually all multicellular eukaryotes, mitochondria are transmitted exclusively through one parent, usually the mother. In this short review, we discuss some of the major consequences of uniparental transmission of mitochondria, including deleterious effects in males and selection for increased transmission throug...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Perlman SJ,Hodson CN,Hamilton PT,Opit GP,Gowen BE

更新日期：2015-08-18 00:00:00