Effectiveness of treatments for severe sepsis: data from the bundle implementation programs.

Abstract:

:In severe sepsis, several studies, a recent meta--analysis and studies evaluating multifaceted strategies for quality improvement, have shown that bundled care can improve survival. Here, the effectiveness of treatments for severe sepsis included in the bundles was analyzed. Despite the observational design of the studies, possible biases are minimized using propensity scores and other adjustments. The results of are very consistent: early sepsis recognition with the administration of broad-spectrum antibiotics in all patients and specific treatments for patients in shock, such as activated protein C, or those on mechanical ventilation play a role in improving sepsis outcome. Hospitals should recognize this new evidence and design strategies to guarantee bundled care for severe sepsis.

journal_name

Minerva Anestesiol

journal_title

Minerva anestesiologica

authors

Ferrer R,Artigas A

subject

Has Abstract

pub_date

2011-03-01 00:00:00

pages

360-5

issue

3

eissn

0375-9393

issn

1827-1596

pii

R02116249

journal_volume

77

pub_type

杂志文章
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    authors: Giron GP,Ori C

    更新日期:1989-03-01 00:00:00

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    authors: Cohen E

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    authors: Pitrolo G,Sculati O,Paolillo GM,Calvi G,Giampiccoli G,Zanchi S

    更新日期:1980-02-01 00:00:00

  • [Anesthesiologic and surgical problems in adenotonsillectomy in pediatric patients. Our current trend].

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    authors: Macarone Palmieri A,Meglio M,Testa D,Salafia M,Iasiello A

    更新日期:1998-12-01 00:00:00

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  • Thrombolytic therapy during cardiopulmonary resuscitation.

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    doi:

    authors: Snyder-Ramos SA,Motsch J,Martin E,Böttiger BW

    更新日期:2002-04-01 00:00:00

  • [Reasons in favor of lumbar puncture diagnosis (or lavage)].

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    pub_type: 杂志文章,评审

    doi:

    authors: Schisano G

    更新日期:1998-04-01 00:00:00

  • [Validity of the V/Q index in the monitoring of critical patients].

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    journal_title:Minerva anestesiologica

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    authors: Donati A,Orsetti G,Bini G,Luzi A,Valente M,Giovannini C,De Ritis GC,Pietropaoli P

    更新日期:1992-01-01 00:00:00

  • Correction to: A year in review in Minerva Anestesiologica 2019. Critical care.

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    doi:10.23736/S0375-9393.18.13041-0

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    pub_type: 杂志文章

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    authors: DE LA Torre-Prados MV,Garcia-DE LA Torre A,Enguix A,Mayor-Reyes M,Nieto-González M,Garcia-Alcantara A

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    abstract::The surgical treatment of cervico-medullary traumas is indicated, in unstable lesions, in large lesions of the mobile rachidic segment in the presence of neurological complications or following worsening of prior neurological symptomatology. The purpose of the operation is at least three-fold: to obtain alignment of v...

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    pub_type: 杂志文章,评审

    doi:

    authors: Fasano VA

    更新日期:1989-03-01 00:00:00

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    abstract::Intranasal dexmedetomidine, although still off-label, recently boasted an increasing consensus for different uses, namely, in diagnostic non-painful procedures, in painful procedures and in surgical premedication. However, at present, there is no consensus regarding indications, dosage and timing for administration. T...

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    authors: Zamperetti N,Mazzon D,Orsi L,Barneschi MG,Marsili M,Rossi C,Primadei M,Ethics Commission of the Italian Society of Anaesthesia, Analgesia, Resuscitation and Intensive Care.

    更新日期:2007-03-01 00:00:00

  • [Effectiveness of regional anesthesia for loco-regional carotid surgery. Retrospective review of 147 interventions].

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    pub_type: 杂志文章

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    authors: Bartoloni A,Savron F,Rigo V,Pasetto A,Spezie C,Ischia A,Perbellini A

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  • [Vecuronium in pediatric anesthesia. Repeated bolus vs continuous infusion].

    abstract::Vecuronium bromide was employed in 26 pediatric patients; 18 received vecuronium infusion and 11 intermittent bolus administration. The aim of the study was to evaluate the pharmacodynamics of the drug, the lack of cumulative properties, the best infusion rate, the possible advantage of the infusion technique. Neuromu...

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    authors: Barbone G,Longo G,Bruno F

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  • Management of acute respiratory complications from influenza A (H1N1) infection: experience of a tertiary-level Intensive Care Unit.

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    authors: Grasselli G,Bombino M,Patroniti N,Foti G,Benini A,Abbruzzese C,Fumagalli R,Pesenti A

    更新日期:2011-09-01 00:00:00

  • [Acute pulmonary edema from dislocation of a laryngeal mask].

    abstract::A case of pulmonary edema secondary to dislocation of laryngeal mask during awakening from anesthesia is described. The complication has been ascribed to physiopathological changes of the alveolo-capillary membrane caused by inspiratory efforts secondary to dislocation of laryngeal mask during awakening from anesthesi...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章

    doi:

    authors: Buttiglieri A,Di Ciero G,Verdecchia C,Gambino A,Fagiano G

    更新日期:1999-09-01 00:00:00

  • [Prolonged neuromuscular block caused by succinylcholine in a patient with normal cholinesterase activity].

    abstract::The authors describe a case of prolonged neuromuscular blockade following suxamethonlum in a patient with a normal cholinesterase activity and dibucaine number > or = 75%. In this case a peripheral nerve stimulator and capnography allowed neuromuscular blockade evaluation and fresh frozen plasma infusion led to a norm...

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    pub_type: 杂志文章

    doi:

    authors: Tritapepe L,Giardini M

    更新日期:1995-01-01 00:00:00

  • [Anesthesiology problems for implant and explant of left ventricular Novacor systems].

    abstract:OBJECTIVES:To review experience with anaesthetic management in patients undergoing a left ventricular assist system (LVAS) Novacor implant as a bridge to cardiac transplantation. DESIGN:Retrospective clinical study. SETTING:Cardiothoracic operating room in a university hospital. PATIENTS:Nine, aged 37-62 years, suff...

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    authors: Domenegati E,Ceriana P,Chiaudani MG,Pagani F

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  • [Hemodynamic and respiratory aspects in orthotopic liver transplantation].

    abstract::Intraoperative hemodynamic and respiratory data from one-year experience of orthotopic liver transplantation with veno-venous bypass (10 cases) were collected. Seven different phases of OLT was submitted to one way analysis of variance. Variability is due to degree and duration of liver disease. Basal conditions inclu...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章

    doi:

    authors: Antonini M,Pastore E,Bufi M,Calzecchi E,Guerricchio R,Della Rocca G,Pinelli ML,Gasparetto A

    更新日期:1990-04-01 00:00:00

  • [Mortality in pediatric anesthesia].

    abstract:UNLABELLED:In last the 50 years many studies have described the causes of mortality. In newborns and infants between 5 and 6 months the risk is higher. The heart is not developed as in older/grown child and these infants need more oxygen than the older ones. Probably, the interaction or interference of positive pressur...

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    pub_type: 杂志文章,评审

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    authors: Rothstein P

    更新日期:2004-05-01 00:00:00

  • Remifentanil for intraoperative analgesia during the endoscopic surgical treatment of pituitary lesions.

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    doi:

    authors: Gargiulo G,Cafiero T,Frangiosa A,Burrelli R,Cortesano P,Cappabianca P,Cavallo LM,Esposito F

    更新日期:2003-03-01 00:00:00

  • Perioperative care of diabetic patient.

    abstract::Diabetes mellitus is a common endocrinopathy. Diabetic patients undergoing surgery have to be carefully evaluated in order to lower the risk of perioperative complications. The author reviews the possible pathological involvement of target organs, focusing on cardiovascular pathology, neuropathy, nephropathy, respirat...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章,评审

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    authors: Scherpereel P

    更新日期:2001-04-01 00:00:00

  • Molecular weight and molar substitution are more important in HES-induced renal impairment than concentration after hemorrhagic and septic shock.

    abstract:BACKGROUND:Clinical studies have raised concerns about the safety of 6% hydroxyethylstarch (HES) 130/0.42, but the pathomechanisms of this renal impairment remain unknown. To evaluate the effects of different HES concentrations, molar substitutions and molecular weights in HES-induced renal impairment, we used a porcin...

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    pub_type: 杂志文章

    doi:

    authors: Simon TP,Thiele C,Schuerholz T,Fries M,Stadermann F,Haase G,Amann KU,Marx G

    更新日期:2015-06-01 00:00:00

  • Extracorporeal respiratory support and minimally invasive ventilation in severe ARDS.

    abstract:BACKGROUND:To evaluate the results of treatment of severe acute respiratory distress syndrome (ARDS) with extracorporeal life support (ECLS), minimal sedation and low pressure supported ventilation in adults. METHODS: DESIGN AND SETTING:observational study in a tertiary referral center, Intensive Care Unit, Astrid Li...

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    pub_type: 临床试验,杂志文章

    doi:

    authors: Frenckner B,Palmér P,Lindén V

    更新日期:2002-05-01 00:00:00

  • Whole-exome sequencing of a family with local anesthetic resistance.

    abstract:BACKGROUND:Local anesthetics (LA) work by blocking sodium conductance through voltage-gated sodium channels. Complete local anesthetic resistance is infrequent, and the cause is unknown. Genetic variation in sodium channels is a potential mechanism for local anesthetic resistance. A patient with a history of inadequate...

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    pub_type: 杂志文章

    doi:

    authors: Clendenen N,Cannon AD,Porter S,Robards CB,Parker AS,Clendenen SR

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  • [A technic of analgesic anesthesia as brief anesthesia].

    abstract::An original technique of analgesic anaesthesia, with the characteristics of brief and out-clinic anaesthesia, has been experimented in a group of patients undergoing light surgery (eye surgery). The technique employs an association of an analgesic--Fentanil--a low dose hypnotic and marked hyperventilation. Recovery ch...

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    pub_type: 杂志文章

    doi:

    authors: Portolano F,de Grazia F,Diana DP,Conte MP

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  • Validation of the Zero-Heat-Flux thermometer (SpotOn®) in major gynecological surgery to monitor intraoperative core temperature: a comparative study with esophageal core temperature.

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