Abstract：
BACKGROUND:To evaluate the results of treatment of severe acute respiratory distress syndrome (ARDS) with extracorporeal life support (ECLS), minimal sedation and low pressure supported ventilation in adults. METHODS: DESIGN AND SETTING:observational study in a tertiary referral center, Intensive Care Unit, Astrid Lindgren Children's Hospital at Karolinska Hospital, Stockholm, Sweden. PATIENTS:thirty-eight patients aged 17-61 years (mean 38) with severe ARDS. The Murray score of pulmonary injury averaged 3.5 (3.0-4.0) and the mean PaO2/FiO2 ratio was 47 (31-65). INTERVENTION:the patients were treated with veno-venous or veno-arterial ECLS after failure of conventional respiratory therapy. A standard ECLS circuit with no heparinized surfaces was used. The patients were minimally sedated and received pressure-supported ventilation. High inspiratory pressures were avoided. RESULTS:25 of the 38 patients survived (total survival rate 66%) after 2-57 days on ECLS (mean 17). Major surgical procedures were performed in several patients during bypass. CONCLUSIONS:A high survival rate can be obtained in adult patients with severe ARDS using ECLS, minimal sedation and pressure-supported ventilation with low inspiratory pressures. Surgical complications are amenable to surgical treatment during ECLS and bleeding problems can be controlled.
journal_name
Minerva Anestesioljournal_title
Minerva anestesiologicaauthors
Frenckner B,Palmér P,Lindén Vkeywords:
subject
Has Abstractpub_date
2002-05-01 00:00:00pages
381-6issue
5eissn
0375-9393issn
1827-1596journal_volume
68pub_type
临床试验,杂志文章abstract：:A prolonged electrocardiographic QTc interval may be unsafe during general anesthesia; thus successful anesthetic management in patients affected by congenital long QT syndrome include avoidance of any event that increases sympathetic activity and drugs that prolong QT interval. Propofol seems to have less effect on t...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1993-07-01 00:00:00
abstract：BACKGROUND:The aim of this study was to investigate long-term outcomes, posthospital trajectories, and quality of life (QOL) in patients ≥80 years admitted to the Intensive Care Unit (ICU) of a tertiary care hospital. METHODS:A 1-year prospective observational cohort analysis was performed. All consecutive patients ≥8...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：10.23736/S0375-9393.16.11434-8
更新日期：2017-06-01 00:00:00
abstract：:The authors illustrate some relevant emerging topics in pediatric anesthesia. Endotracheal cuffed tubes have entered into routine clinical practice in younger patients. Concerns about tracheal stenosis were overcome when manufactures began to produce a new class of high volume, low pressure endotracheal tubes. Ultraso...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2009-04-01 00:00:00
abstract：:The overall use of allogeneic blood transfusions in clinical practice remains relatively high and still varies widely among centres and practitioners. Moreover, allogeneic blood transfusions have historically been linked with risks and complications: some of them (e.g. transfusion reactions and transmission of pathoge...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2015-10-01 00:00:00
abstract：:Immediately following delivery a newborn infant was severely depressed. Because no respiratory effort was made and copious mucus was present, a Cole endotracheal tube was easily inserted into the trachea. Because of a mistaken manoeuvre for fastening the tube, the plastic adapter connection became dislodged from the t...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1994-04-01 00:00:00
abstract：:Diabetes mellitus is a common endocrinopathy. Diabetic patients undergoing surgery have to be carefully evaluated in order to lower the risk of perioperative complications. The author reviews the possible pathological involvement of target organs, focusing on cardiovascular pathology, neuropathy, nephropathy, respirat...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2001-04-01 00:00:00
abstract：:Although the central nervous system is the primary endpoint of most general anesthetics, it is still the least monitored organ in clinical anesthesiology. In the last decade, technological research has expanded the application of near-infrared spectroscopy to allow continuous, non-invasive, and bedside monitoring of c...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2006-07-01 00:00:00
abstract：:Various aspects of the critically ill patient sharing pain, physical distress, anxiety, environmental components, predispose him to develop some sleep disorders (SD). We studied 20 conscious patients, age 16-80 (mean 48.15 SD of mean +/- 25), undergoing ICU mean 14.3 days (SD of mean +/- 7.5), to evaluate SD rate and ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1992-09-01 00:00:00
abstract：BACKGROUND:Few studies have investigated the incidence of pulmonary anaerobes in a specific population in surgical Intensive Care Unit (ICU). The objective of this work was to determine the incidence of anaerobes in surgical ICU patients with suspected pneumonia. METHODS:This was a prospective observational, single-ce...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2014-10-01 00:00:00
abstract：BACKGROUND:Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is an effective rescue therapy for improving oxygenation in selected severe acute respiratory distress syndrome (ARDS). Prone position (PP) is usually considered before vvECMO and few data are available on the association of PP during VV-ECMO. Thus, w...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2014-03-01 00:00:00
abstract：:The surgical treatment of cervico-medullary traumas is indicated, in unstable lesions, in large lesions of the mobile rachidic segment in the presence of neurological complications or following worsening of prior neurological symptomatology. The purpose of the operation is at least three-fold: to obtain alignment of v...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：1989-03-01 00:00:00
abstract：:During video assisted thoracoscopy (VAT) the lung should be well collapsed. When the separation of the lungs is strictly indicated, use of difficult tube, such as double lumen tube (DLT) or Univent tube cannot be avoided, despite the presence of a difficult airway. If a patient has a recognized difficult airway, awake...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2004-05-01 00:00:00
abstract：:Spontaneous thrombolysis is a quite rare event. It's not predictable through a clinical examination of the patient, but there are some markers that are supposed to be diagnostic because of the high percentage of their occurrence in coincidence with spontaneous thrombolysis. The goal of the authors is to describe a cas...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1993-09-01 00:00:00
abstract：: ...
journal_title：Minerva anestesiologica
pub_type： 评论,信件
doi：10.23736/S0375-9393.19.13835-7
更新日期：2019-10-01 00:00:00
abstract：UNLABELLED:The aim of this study is the comparison between the use of bupivacaine alone and a mixture of bupivacaine, mepivacaine and hyaluronidase in both retrobulbar and peribulbar blockades for eye surgery. Three hundred ninety-nine consecutive adult patients scheduled for cataract surgery with regional anaesthesia ...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1999-11-01 00:00:00
abstract：OBJECTIVE:Inhaled NO can improve arterial oxygenation in ARDS. We evaluated the incidence and the magnitude of this effect during a short test of NO inhalation. This was performed in 24 consecutive mechanically ventilated patients with ARDS in order to assess the interest of NO for the therapy of hypoxemia in each case...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1995-04-01 00:00:00
abstract：:Neuraxial block for labor analgesia is widely accepted and highly effective. Much progress has been achieved in terms of providing safer and more efficacious analgesia. Emphasis has been placed on maternal autonomy and individualization of therapy. The introduction of the combined spinal-epidural technique in the labo...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2008-03-01 00:00:00
abstract：:In this paper the Authors describe the anesthetic techniques used for abdominal surgery in a 19 year-old woman with "central-core disease". This uncommon congenital neuromuscular disorder is frequently related to malignant hyperthermia syndrome. Total intravenous anesthesia with the association propofol-fentanyl was w...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
abstract：BACKGROUND:Pneumonia is the primary source of sepsis and is significantly associated with mortality. However, only a few studies focus on its clinical characteristics and outcomes. METHODS:We evaluated 500 intensive care unit patients who met severe sepsis or septic shock criteria, dividing them into two distinct grou...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,多中心研究
doi：
更新日期：2013-12-01 00:00:00
abstract：: ...
journal_title：Minerva anestesiologica
pub_type： 评论,信件
doi：10.23736/S0375-9393.19.13630-9
更新日期：2019-07-01 00:00:00
abstract：BACKGROUND:Disorders in cerebral circulation following elevated intra-abdominal pressure (IAP) may lead to silent brain ischemia, which can be serious problem in sedated critically ill patients. The aim of the present study was to analyse the possible association between jugular venous bulb pressure (JVBP) and jugular ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2014-07-01 00:00:00
abstract：BACKGROUND:Trapeziectomy is one of the most painful procedures in ambulatory surgery. This prospective randomized trial aimed to compare postoperative pain control using distal peripheral nerve blocks (dPNB) with a low concentration of a long-acting local anesthetic versus conventional systemic analgesia. METHODS:Fift...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,随机对照试验
doi：10.23736/S0375-9393.18.12291-7
更新日期：2018-11-01 00:00:00
abstract：BACKGROUND:Postoperative opioid analgesia increases the incidence of postoperative nausea and vomiting (PONV). We investigated whether a combination of the neurokinin-1 antagonist aprepitant and dexamethasone decreases PONV incidence compared with dexamethasone alone in high-risk patients receiving continuous epidural ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2015-04-01 00:00:00
abstract：:A size 3 laryngeal mask was used in 20 patients who underwent elective general surgery. It consists of a silicon tube attached to mask which must be inserted into the hypopharynx and then inflated. No curarisation nor laryngoscopy is needed. Operations were performed in assisted or spontaneous ventilation, with good a...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
abstract：:The utility of laparoscopic cholecystectomy in reducing postoperative pain and patient's hospital discharge is already known. Nevertheless peritoneal gas insufflation required by surgical procedure can modify respiratory homeostasis during general anesthesia. The aim of this study was to evaluate the effect of laparos...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：BACKGROUND:When patients are incompetent, advance directives (AD) can help physicians take crucial medical decisions. However, prevalence remains low. The objective was to investigate physicians' perspectives and attitudes towards AD in order to determine potential targets for improvement. METHODS:Observational study ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2015-10-01 00:00:00
abstract：:Asthma and chronic obstructive pulmonary diseases (COPD) lead to functional obstruction of airways, identified by increased inspiratory and expiratory resistances. Increased expiratory resistances cause, in turn, a reduction in expiratory flow. The analysis of flow-volume loops shows that, as the disease progresses, t...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2001-04-01 00:00:00
abstract：UNLABELLED:In last the 50 years many studies have described the causes of mortality. In newborns and infants between 5 and 6 months the risk is higher. The heart is not developed as in older/grown child and these infants need more oxygen than the older ones. Probably, the interaction or interference of positive pressur...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2004-05-01 00:00:00
abstract：:Nosocomial bloodstream infections (BSIs) have become an important cause of morbidity and mortality, particularly in intensive care units (ICUs). Gram-positive organisms are the prevalent causes of antibiotic-resistant BSI, especially Staphylococcus aureus, coagulase-negative staphylococci and enterococci. In recent ye...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2011-08-01 00:00:00
abstract：:Recently, efforts have been undertaken to investigate the effects of thrombolysis during cardiopulmonary resuscitation (CRP) in patients suffering from massive pulmonary embolism or acute myocardial infarction. In up to 70% of patients with cardiac arrest, one of these two diseases is the underlying cause of deteriora...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2002-04-01 00:00:00
