Abstract：
UNLABELLED:The aim of this study is the comparison between the use of bupivacaine alone and a mixture of bupivacaine, mepivacaine and hyaluronidase in both retrobulbar and peribulbar blockades for eye surgery. Three hundred ninety-nine consecutive adult patients scheduled for cataract surgery with regional anaesthesia were included in this prospective, randomized and partially blind study. Peribulbar blockade was performed on 199 patients (group P). Ninety-nine of them received a mixture of local anaesthetics and hyaluronidase (sub-group M), while 100 received bupivacaine alone (sub-group B). Retrobulbar blockade was performed on 200 patients (group R): 100 of them received the mixture with hyaluronidase (sub-group M), while 100 received bupivacaine (sub-group B). The interval between anaesthesia and motor blockade (onset time), the presence of residual ocular movements, the need of further anaesthesia, the quality of anaesthesia, the ocular tone, the length of anaesthesia and possible complications were registered. RESULTS:Retrobulbar blockade has the only advantage of a shorter onset time, while peribulbar blockade shows a longer anaesthetic effect. Mixture with hyaluronidase (the sub-group M) has a shorter onset time, a lesser need of further anaesthesia, fewer residual ocular movements and a better quality of anaesthesia. CONCLUSIONS:Local anaesthetics mixture with hyaluronidase associated with peribulbar blockade presents the advantages of rapidity, duration and better quality without the risks of retrobulbar blockade side effects.
journal_name
Minerva Anestesioljournal_title
Minerva anestesiologicaauthors
Costa P,Papurel Begin G,Coaloa M,Villa C,Ravera E,Hellmann F,Di Giovanni M,Bono Dkeywords:
subject
Has Abstractpub_date
1999-11-01 00:00:00pages
775-83issue
11eissn
0375-9393issn
1827-1596journal_volume
65pub_type
临床试验,杂志文章,随机对照试验abstract：INTRODUCTION:Although many drugs have been studied to prevent postoperative shivering, their comparative effectiveness is unknown. We attempted to assess the comparative effectiveness of the pharmacologic strategies to prevent shivering after surgery including intravenous (IV) and intrathecal (IT) meperidine, IV and IT...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,meta分析,评审
doi：10.23736/S0375-9393.18.12813-6
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:Reduced glutathione (GSH) an antioxidant used for i.v. or i.m. administrations, prepared as powder to be diluted in distilled water just before injection (Tationil 600), could lose its antioxidant properties when added to various infusions currently utilized in anesthesia and reanimation. AIM OF THE WORK:Ev...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1995-10-01 00:00:00
abstract：BACKGROUND:Predictive models of acute kidney injury after cardiac surgery (CS-AKI) include emergency surgery and patients with hemodynamic instability. Our objective was to evaluate the performance of validated predictive models (Thakar and Demirjian) in elective cardiac surgery and to propose a better score in the cas...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,多中心研究
doi：10.23736/S0375-9393.18.12257-7
更新日期：2019-01-01 00:00:00
abstract：:Mechanical ventilation may induce or aggravate lung injury, a phenomenon known as ventilator induced lung injury (VILI). On a macroscopic level, the effects of mechanical stress and strain on lung tissue are well described. Increased tidal volumes may lead to volutrauma, raised airway pressures may cause barotrauma an...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
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abstract：:Mechanical ventilation (MV) with positive pressure insufflations of gas into the lung may be required to ensure sufficient oxygenation of blood and elimination of carbon dioxide in acute respiratory failure. Interfacing spontaneous breathing and mechanical ventilation has been used to improve gas exchange and may offe...
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更新日期：2006-04-01 00:00:00
abstract：:Pulmonary complications are a source of greater postoperative morbidity and mortality and longer hospital stays. Although many factors have been implicated as predictors, few models have been developed with the rigorous methodology required for clinically useful tools. In this article we attempt to describe what to lo...
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pub_type： 杂志文章,评审
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journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
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journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2001-05-01 00:00:00
abstract：:Paracetamol is widely used in the management of acute and chronic pain. The purpose of this review is to give anesthesiologists answers to some of the most common questions about paracetamol, specifically the following questions. What is the mechanism of action of paracetamol? Is paracetamol a NSAID? Which endogenous ...
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更新日期：2011-04-01 00:00:00
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journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1980-08-01 00:00:00
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journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1981-05-01 00:00:00
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journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2007-05-01 00:00:00
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doi：
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pub_type： 杂志文章
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更新日期：1979-09-01 00:00:00
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journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
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pub_type： 临床试验,杂志文章
doi：
更新日期：1996-05-01 00:00:00
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更新日期：1995-01-01 00:00:00
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pub_type： 临床试验,杂志文章,随机对照试验,评审
doi：
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pub_type： 杂志文章
doi：10.23736/S0375-9393.18.12720-9
更新日期：2018-10-01 00:00:00
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pub_type： 杂志文章,评审
doi：
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