Abstract：
BACKGROUND:The aim was to ascertain the prognostic value of mid-regional pro-adrenomedullin (MR-proADM), measured within 24 hours from the onset of septic shock (SS). METHODS:We performed a prospective, observational study on all patients admitted to our hospital's Intensive Care Unit with SS over a one year period from January to December 2011 to examine the outcomes in 100 consecutive SS cases. Demographic data and severity score (APACHEII and SOFA) were recorded. MR-proADM, C-reactive protein and procalcitonin were measured within the first 24 hours from SS onset. The outcome variable studied was 28-day mortality. Data were evaluated with non-parametric statistics bivariant and multivariate analyses for survival analysis. RESULTS:In patients who died within 28 days (36%), MR-proADM, Lactate, APACHE II as well as SOFA were significantly higher compared with survivors. MR-proADM showed the best association with 28-day mortality, as well as a prognostic value (logrank test: P=0.0012). Statistical significance was also seen in the Cox regression analysis (P=0.0004) for all patients with a Relative Risk of 1.26 times that of the baseline for each mmol/L of increase in MR-proADM. CONCLUSIONS:In our study MR-proADM levels measured on admission correlates with 28-day mortality in patients with septic shock.
journal_name
Minerva Anestesioljournal_title
Minerva anestesiologicaauthors
DE LA Torre-Prados MV,Garcia-DE LA Torre A,Enguix A,Mayor-Reyes M,Nieto-González M,Garcia-Alcantara Asubject
Has Abstractpub_date
2016-07-01 00:00:00pages
760-6issue
7eissn
0375-9393issn
1827-1596pii
R02Y9999N00A16031102journal_volume
82pub_type
杂志文章abstract：OBJECTIVE:To evaluate the incidence of colonization and infection by methicillin-resistant in PICU. DESIGN:Prospective cohort study during 2 years for the surveillance of nosocomial infections. SETTING:Four beds Pediatric Intensive Care Unit. PATIENTS:We studied two-hundred patients with duration of hospitalization ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1995-06-01 00:00:00
abstract：:Multimodal pain management, combining analgesics with different mode of action in order to minimize occurrence of side-effects still providing safe and efficacious pain management after ambulatory surgery has become standard of care. The combined use of local anaesthesia in order to reduce noxious influx during the pr...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2013-09-01 00:00:00
abstract：:The particular characteristics of atracurium in comparison with available relaxant agents are briefly analyzed. Afterwards the results of a clinical investigation regarding a group of 56 patients who underwent major abdominal surgery are referred to. The most important elements of this investigation involve: the primi...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：1989-05-01 00:00:00
abstract：:Coagulopathy associated with massive operative blood loss is an intricate, multicellular and multifactorial event. Massive bleeding can either be anticipated (during major surgery with high risk of bleeding) or unexpected. Management requires preoperative risk evaluation and preoperative optimization (discontinuation ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2007-07-01 00:00:00
abstract：:Surgery is currently the treatment of choice for acutely ruptured aneurysms, representing an efficient option both in the short and long term. We believe that the endovascular option may be of help in high surgical-risk cases. ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1998-04-01 00:00:00
abstract：BACKGROUND:General anesthesia utilizing inhalational agents without intravenous (IV) access for minor procedures is controversial. Eliminating IV access increases efficiency and patient satisfaction; however, the ability to introduce rapid acting medications into the circulation during an unanticipated emergency become...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：10.23736/S0375-9393.17.11565-8
更新日期：2017-07-01 00:00:00
abstract：:Clinical neurophysiology is both an extension of clinical examination and an integration of neuroimaging. It plays a role in diagnosis, prognosis and monitoring in the Intensive Care Unit (ICU). Electroencephalography (EEG) and somatosensory evoked potentials (SEPs) are the most informative neurophysiological tests. B...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2012-09-01 00:00:00
abstract：:The anesthetic management of a 58 year-old-male suffering from idiopathic pulmonary fibrosis associated with a previous experience of altered dose-response relationship to muscle relaxants is reported. He underwent a gastroendoscopic surgical procedure. After intravenous atropine, remifentanil 3.0 microg kg(-1) was in...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2002-11-01 00:00:00
abstract：:This year, the US Institute of Medicine has estimated that medical errors kill up to 98,000 Americans each year,1 a problem surpassing automobile fatalities. For patients on the medical ward, drug therapy is the primary intervention they are receiving yet medication errors occur in as many as 4% of inpatients.2 Althou...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2000-05-01 00:00:00
abstract：BACKGROUND:The aim was to investigate whether tramadol had toxic effect on cerebral neurons and/or spinal cord neurons when it was administered into the cerebrospinal fluid. Due to lipid peroxidation (LPO) and myeloperoxidation (MPO) levels are not specific predictors of neuronal damage, these biochemical markers of ti...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2014-08-01 00:00:00
abstract：:Natremia belongs to the toolbox of the practicing intensivist. It is an indicator of the hydration status, which is an item that must be continuously monitored in critically ill patients. Hyponatremia is not rare (1% to 2% of hospitalised patients), and hypernatremia is about 10 times less frequent while hypernatremia...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2006-06-01 00:00:00
abstract：:Multiple sclerosis is a progressive demyelinating disease which affects large areas of the brain and of the spinal cord. Stressful events, surgical procedures, general anaesthesia and central blocks seem to be responsible for relapses, with worsening of the disease. So, when we scheduled 2 patients with multiple scler...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2005-05-01 00:00:00
abstract：OBJECTIVE:To set up an index for the evaluation of type of interventions and procedures applied a prerequisite for the evaluation of appropriateness of ICU's activity. DESIGN:Observation prospective study. PATIENTS:2507 patients out of the 5030 enrolled in the cohort study. MEASUREMENTS:A cross-sectional assessment ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1997-11-01 00:00:00
abstract：:The successful management of 2 cases of rare myopathies, who underwent hemithyroidectomy, is here reported. Anaesthesia was induced with TPS and fentanyl, and maintained with isoflurane. Neuromuscular blockade was achieved by atracurium; neuromuscular monitoring by Neurostar-Medeleck was performed. This intraoperative...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1991-07-01 00:00:00
abstract：:Over the last two decades, lung transplantation emerged as the standard of care for patients with advanced and terminal lung disease. Despite the increment in lung transplantation rates, in 2016 the overall mortality while on waiting list in Italy reached 10%, whereas only 39% of the wait-list patients were successful...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：10.23736/S0375-9393.17.12130-9
更新日期：2018-02-01 00:00:00
abstract：:A 74-year-old patient was submitted to urgent surgery for intestinal occlusion. After the induction of the anaesthesia, tracheal intubation failed since no progression of Eshmann tracheal tube introducer was possible. The ventilation was difficult and a laryngeal mask was inserted. After oxygenation, the tracheal tube...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2012-02-01 00:00:00
abstract：:A correct assessment of arterial pressure state during SAH is one of most critical issue in neurologic intensive care. It is important to evaluate two different clinical conditions: a) during SAH when the aneurysm is open, b) after aneurysmal clipping or embolization. The authors propose pressure parameters appropriat...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1998-05-01 00:00:00
abstract：:Sepsis is a condition at high risk for the patients to develop organ(s) or system dysfunction/failure and represent a very limiting process for survival. Researchers and clinicians proposed standardization of terminology for sepsis and related problems to improve communication and to evaluate the efficacy of preventiv...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：1999-07-01 00:00:00
abstract：:The term "chronic" is often used in daily clinical practice to indicate a type of pain that lasts over time and is accompanied by diagnostic and therapeutic difficulties. The common feeling is that in this category are actually collected many different clinical cases with the unique characteristic that the pain lasts ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2012-06-01 00:00:00
abstract：:During the last decade, inhaled antibiotics, especially colistin, has been widely used worldwide as a therapeutic option, supplementary to conventional intravenous antibiotics, for the treatment of multidrug-resistant (MDR) Gram-negative nosocomial and ventilator-associated pneumonia (VAP). Antimicrobial aerosols are ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2014-02-01 00:00:00
abstract：BACKGROUND:Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is an effective rescue therapy for improving oxygenation in selected severe acute respiratory distress syndrome (ARDS). Prone position (PP) is usually considered before vvECMO and few data are available on the association of PP during VV-ECMO. Thus, w...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2014-03-01 00:00:00
abstract：:In the last decade, there has been increasing use of the da Vinci® robot surgical system to perform minimally invasive thoracic surgery. The robotic technology can be applied for surgery of the lungs, mediastinum, and esophagus. A number of case reports have been shown steep learning curve, and promising surgical outc...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2014-01-01 00:00:00
abstract：:Intravenous administration of 400-600 mg/day potassium canrenoate normalised plasma osmolarity and permitted rapid re-establishment of the metabolic picture in 9/12 patients with hyperosmolarity admitted to a resuscitation department for complex physiopathological pictures. The soundness of the drug in this sense is a...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1979-09-01 00:00:00
abstract：:All 54 chest trauma patients admitted to Resuscitation II of Pavia's S. Matteo Polyclinic in the period 1974-1979 have been reviewed in a critical analysis. Particular attention was paid to mortality in relation to age, associated pathology, treatment and the complications arising during the course of the trauma. Resu...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1981-11-01 00:00:00
abstract：BACKGROUND:The coronary sinus oxygen saturation (SO2) can affect the oxygen saturation of the superior vena cava (superior cava SO2) and the pulmonary artery (pulmonary artery SO2), causing a gradient between the latter two (ΔSO2), as has been observed in different physiological and pathological conditions. The objecti...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2011-06-01 00:00:00
abstract：:A consecutive series of 41 patients aged less than 16 and admitted to the Department of Neurosurgery of the University of Milan in the period 1977-1978 following serious cranioencephalic trauma with Glasgow Coma Score (GCS) less than or equal to 7, duration of coma longer than 24 h and CT picture of diffuse lesion has...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1989-04-01 00:00:00
abstract：:The overall use of allogeneic blood transfusions in clinical practice remains relatively high and still varies widely among centres and practitioners. Moreover, allogeneic blood transfusions have historically been linked with risks and complications: some of them (e.g. transfusion reactions and transmission of pathoge...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2015-10-01 00:00:00
abstract：BACKGROUND:The goal of this paper was to investigate the association between patterns of intracranial hypertension (IH) and outcomes, to describe the treatment of patients with different patterns of IH, and to examine whether IH is an independent predictor of mortality and unfavourable outcome, respectively. METHODS:A...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2014-12-01 00:00:00
abstract：:The authors analyze the physiological basis, technical aspects and clinical usefulness of several methods for pressure-volume curves determinations in mechanically ventilatory, acute respiratory failure patients. ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2000-05-01 00:00:00
abstract：:Excessive adrenergic stimulation may be associated with several adverse events and contribute to increase mortality in critically ill septic patients. Few clinical data exist on the effects of adrenergic blockade in this setting. The objective of this study was to investigate the effect of a short acting b-blocker (es...
journal_title：Minerva anestesiologica
pub_type： 评论,杂志文章
doi：
更新日期：2014-02-01 00:00:00
