Treatment of children with B-cell non-Hodgkin lymphoma in a low-income country.

abstract：BACKGROUND:Neonatal leukemia characterized by early stem cell origin and extramedullary infiltration in the first 4 weeks of life is rare. We analyzed the features and outcome of neonatal leukemia in Japan to establish an appropriate treatment strategy for this rare disorder. PROCEDURE:Patients with infant leukemia re...

journal_title：Pediatric blood & cancer

authors： Ishii E,Oda M,Kinugawa N,Oda T,Takimoto T,Suzuki N,Kosaka Y,Ohara A,Ogawa A,Ishii M,Sakata N,Okamura T,Koike K,Kojima S,Horibe K,Mizutani S

更新日期：2006-09-01 00:00:00

abstract：:Familial adenomatous polyposis (FAP) due to APC mutation is associated with an increased risk of hepatoblastoma. All cases of hepatoblastoma in patients with FAP reported in the literature were reviewed. One hundred and nine patients were identified. Thirty-five patients (of 49 with data) were diagnosed with hepatobla...

journal_title：Pediatric blood & cancer

authors： Trobaugh-Lotrario AD,López-Terrada D,Li P,Feusner JH

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Thyroid dysfunction has been reported in up to 52% of patients 1.4 years after treatment with (131) I-Metaiodobenzylguanidine (MIBG) in children with neuroblastoma (NBL), despite the use of potassium-iodide (KI). Our aim was to investigate if the incidence and severity of thyroid damage increases in time. M...

journal_title：Pediatric blood & cancer

authors： Clement SC,van Eck-Smit BL,van Trotsenburg AS,Kremer LC,Tytgat GA,van Santen HM

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Hypogammaglobulinemia (hypo-IgG) is common early post-HSCT in children, occasionally necessitating long-term immunoglobulin (Ig) G replacement therapy. IgG replacement may not reduce mortality, although infectious complications are decreased PROCEDURE:Clinical data and samples from 86 children were analyzed...

journal_title：Pediatric blood & cancer

authors： Sundin M,Remberger M,Lindqvist H,Omazic B,Sundberg B,Uzunel M,Winiarski J

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:To develop an objective tool for assessing disease activity in patients with Langerhans cell histiocytosis (LCH). METHOD:Scoring system was developed and applied to a database containing information on 612 patients. RESULTS:At diagnosis, the score distribution was highly asymmetrical: the score was between ...

journal_title：Pediatric blood & cancer

authors： Donadieu J,Piguet C,Bernard F,Barkaoui M,Ouache M,Bertrand Y,Ibrahim H,Emile JF,Hermine O,Tazi A,Genereau T,Thomas C

更新日期：2004-12-01 00:00:00

abstract：:Squamous cell carcinoma of the anal canal in children is rare. To date, the etiology and outcome of this condition have been not fully understood. Here, we report an 11-year-old child with anal canal cancer who had concomitant disorders of sex development. Radiotherapy followed by salvage surgery achieved disease-free...

journal_title：Pediatric blood & cancer

authors： Watanabe T,Horikawa R,Masaki H,Yoshioka T,Matsumoto K,Kanamori Y

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Prior reviews of phase I pediatric oncology trials involving primarily cytotoxic agents have reported objective response rates (ORRs) and toxic death rates of 7.9-9.6% and 0.5%, respectively. These data may not reflect safety and efficacy in phase I trials of molecularly targeted (targeted) drugs. METHODS:A...

journal_title：Pediatric blood & cancer

authors： Dorris K,Liu C,Li D,Hummel TR,Wang X,Perentesis J,Kim MO,Fouladi M

更新日期：2017-03-01 00:00:00

abstract：:Most publications report the adverse (negative) health issues in childhood cancer survivors. Presenting information to the newly diagnosed patient in a positive manner is advocated, while noting that recurrence is the most likely adverse event. Re-analysis of population-based studies on life-threatening toxicities fro...

journal_title：Pediatric blood & cancer

authors： Fryer C

更新日期：2011-12-15 00:00:00

abstract：:The fundamental purposes underlying formal health care transition from the pediatric to adult setting for young adult survivors of childhood cancer are to facilitate the continuous, medically and developmentally appropriate implementation of risk-based guidelines for the monitoring and management of late effects of ch...

journal_title：Pediatric blood & cancer

authors： Freyer DR,Brugieres L

更新日期：2008-05-01 00:00:00

abstract：:Unstable hemoglobin variants represent a rare etiology of congenital hemolytic anemia. Without a high index of suspicion, plus proper laboratory testing and interpretation, the correct diagnosis can be elusive. We report on five children who were initially thought to have other congenital disorders such as hereditary ...

journal_title：Pediatric blood & cancer

authors： Yates AM,Mortier NA,Hyde KS,Hankins JS,Ware RE

更新日期：2010-12-15 00:00:00

abstract：:In Mexico, childhood cancer incidence and mortality have increased in the last decade. Through government actions since 2005, the Popular Medical Insurance (PMI) program for childhood cancer was created. The objective of PMI was to offer early cancer diagnosis, standardized treatment regimens, and numerous pediatric o...

journal_title：Pediatric blood & cancer

authors： Rivera-Luna R,Zapata-Tarres M,Shalkow-Klincovstein J,Velasco-Hidalgo L,Olaya-Vargas A,Finkelstein-Mizrahi N,Cárdenas-Cardós R,Aguilar-Ortiz MR

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Survival rates for patients with bone tumors have increased dramatically over the past few decades. Unfortunately, many patients face functional limitations resulting from disease management, but there is little evidence regarding physical functioning in adolescents with bone tumors. This lack is largely due...

journal_title：Pediatric blood & cancer

authors： Pakulis PJ,Young NL,Davis AM

更新日期：2005-10-15 00:00:00

abstract：:We report successful bone marrow transplantation in an 11-year-old male with chronic myeloid leukemia from his HLA-identical sibling selected by preimplantation HLA testing. Because collection of cord blood failed, the transplantation was performed when the donor reached the age of 19 months, and sufficient bone marro...

journal_title：Pediatric blood & cancer

authors： Goussetis E,Constantoulakis P,Kitra V,Peristeri I,Mastrominas M,Baka M,Papadimitropoulos M,Karamolegos C,Paisiou A,Vasilatou-Kosmidis H,Graphakos S

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Testicular germ cell tumors (T-GCTs) occur from infancy to adulthood, and are the most common solid tumor in adolescent and young adult males. Traditionally, pediatric T-GCTs were perceived as more indolent than adult T-GCTs. However, there are few studies comparing these groups and none that specifically ev...

journal_title：Pediatric blood & cancer

authors： Cost NG,Lubahn JD,Adibi M,Romman A,Wickiser JE,Raj GV,Sagalowsky AI,Margulis V

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Currently, there is no standardized treatment for adolescents, aged 15 years or older, with mature B-cell non-Hodgkin lymphoma (B-NHL), although this age group has been reported to have a poorer prognosis than younger patients. PROCEDURE:The present study analyzed the data of 321 patients with B-NHL, enroll...

journal_title：Pediatric blood & cancer

authors： Sekimizu M,Hashimoto H,Mori T,Kobayashi R,Horibe K,Tsurusawa M

更新日期：2018-08-01 00:00:00

abstract：:Medulloblastomas (MB) are classified in four subgroups: the well defined WNT and Sonic Hedgehog (SHH) subgroups, and the less defined groups 3 and 4. They occasionally occur in the context of a cancer predisposition syndrome. While germline APC mutations predispose to WNT MB, germline mutations in SUFU, PTCH1, and TP5...

journal_title：Pediatric blood & cancer

authors： Bourdeaut F,Miquel C,Richer W,Grill J,Zerah M,Grison C,Pierron G,Amiel J,Krucker C,Radvanyi F,Brugieres L,Delattre O

更新日期：2014-02-01 00:00:00

abstract：:Anaphylactic/anaphylactoid reaction to methotrexate (MTX) is uncommon. It may occur with the first dose (non-allergic reactions) or after a previous exposure to the drug (allergic or specific reactions). Desensitization has been shown effective in children with allergic-type reactions permitting the continuation of hi...

journal_title：Pediatric blood & cancer

authors： Oulego-Erroz I,Maneiro-Freire M,Bouzón-Alejandro M,Vázquez-Donsión M,Couselo JM

更新日期：2010-09-01 00:00:00

abstract：:While encapsulated bacterial agents, particularly Streptococcus pneumoniae, are recognized as important microbes that are associated with serious illness in hosts with sickle cell disease (SCD), multiple pathogens are implicated in infectious manifestations of SCD. Variations in clinical practice have been an obstacle...

journal_title：Pediatric blood & cancer

authors： Obaro SK,Iroh Tam PY

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Clinical characteristics and optimal treatment strategies for spindle cell/sclerosing rhabdomyosarcoma (ssRMS) have not been well established because of its rarity. PROCEDURE:Retrospective re-evaluation of sarcoma specimens (1997-2014) identified 16 ssRMSs (median age 20 years, range 7-39 years). Clinicopat...

journal_title：Pediatric blood & cancer

authors： Yasui N,Yoshida A,Kawamoto H,Yonemori K,Hosono A,Kawai A

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:We sought to determine the risk of bacteremia in a cohort of outpatient febrile nonneutropenic pediatric oncology patients and to assess clinical characteristics that may influence decisions regarding empiric antibiotic therapy. PROCEDURE:A single institution retrospective cohort study was performed of outp...

journal_title：Pediatric blood & cancer

authors： Kelly MJ,Vivier PM,Panken TM,Schwartz CL

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Long-term adverse effects of Imatinib in children with chronic myeloid leukemia (CML) are uncertain. The aim was to study the effect of imatinib on growth in children with CML. PROCEDURE:Children ≤13 years of age at diagnosis were enrolled retrospectively, from 2004 to 2011, from a single center in India. P...

journal_title：Pediatric blood & cancer

authors： Bansal D,Shava U,Varma N,Trehan A,Marwaha RK

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:The neurokinin-1 receptor antagonist aprepitant, plus a 5HT3 antagonist and corticosteroid is well-tolerated and effective in preventing chemotherapy-induced nausea and vomiting in adults but has not been formally assessed in adolescents. PROCEDURE:Patients age 11-19 years old receiving emetogenic chemother...

journal_title：Pediatric blood & cancer

authors： Gore L,Chawla S,Petrilli A,Hemenway M,Schissel D,Chua V,Carides AD,Taylor A,Devandry S,Valentine J,Evans JK,Oxenius B,Adolescent Aprepitant in Cancer Study Group.

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Contemporary descriptions of classical Hodgkin lymphoma (cHL) are lacking from sub-Saharan Africa where human immunodeficiency virus (HIV) and Epstein-Barr virus (EBV) are prevalent. METHODS:We describe a prospective cHL cohort in Malawi enrolled from 2013 to 2015. Patients received standardized treatment a...

journal_title：Pediatric blood & cancer

authors： Westmoreland KD,Stanley CC,Montgomery ND,Kaimila B,Kasonkanji E,El-Mallawany NK,Wasswa P,Mtete I,Butia M,Itimu S,Chasela M,Mtunda M,Chikasema M,Makwakwa V,Kampani C,Dhungel BM,Sanders MK,Krysiak R,Tomoka T,Liomba NG

更新日期：2017-05-01 00:00:00

abstract：:During ALL chemotherapy, a 4-year-old patient presented with febrile neutropenia and abdominal pain. Ultrasound examinations were repeatedly normal. Computerized tomography on day 7 demonstrated appendicitis and multiple hepatic foci identified as mucormycosis (Absidia corymbifera). Successful outcome was achieved by ...

journal_title：Pediatric blood & cancer

authors： Lüer S,Berger S,Diepold M,Duppenthaler A,von Gunten M,Mühlethaler K,Wolf R,Aebi C

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Pulmonary hypertension (PHTN) is a potentially life-threatening complication, detected by echocardiographic evidence of elevated tricuspid regurgitant velocity (TRV). This condition has been described in adults with sickle cell disease (SCD) and other hemolytic disorders; however, there is little information...

journal_title：Pediatric blood & cancer

authors： Ambrusko SJ,Gunawardena S,Sakara A,Windsor B,Lanford L,Michelson P,Krishnamurti L

更新日期：2006-12-01 00:00:00

abstract：:Family financial hardship has emerged as a burden of pediatric cancer treatment with negative implications for family well-being. As part of an extensive project to create evidence-based standards for the psychosocial care of children with cancer, we performed a literature review of pediatric cancer-associated financi...

journal_title：Pediatric blood & cancer

authors： Pelletier W,Bona K

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The male excess in childhood cancer incidence is well-established; however, the underlying biologic mechanisms remain unknown. Examining the association between male sex and childhood cancer by single year of age and tumor type may highlight important periods of risk such as variation in growth and hormonal ...

journal_title：Pediatric blood & cancer

authors： Williams LA,Richardson M,Marcotte EL,Poynter JN,Spector LG

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:A desperate need for novel therapies in pediatric ependymoma (EPN) exists, as chemotherapy remains ineffective and radiotherapy often fails. EPN have significant infiltration of immune cells, which correlates with outcome. Immune checkpoint inhibitors provide an avenue for new treatments. This study characte...

journal_title：Pediatric blood & cancer

authors： Witt DA,Donson AM,Amani V,Moreira DC,Sanford B,Hoffman LM,Handler MH,Levy JMM,Jones KL,Nellan A,Foreman NK,Griesinger AM

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:To analyze the impact of mediastinal irradiation on the incidence of cardiac late effects in long-term survivors of pediatric Hodgkin disease (HD). METHODS:The study cohort comprised 1,132 survivors of HD who received treatment before 18 years of age in consecutive trials between 1978 and 1995. They had mai...

journal_title：Pediatric blood & cancer

authors： Schellong G,Riepenhausen M,Bruch C,Kotthoff S,Vogt J,Bölling T,Dieckmann K,Pötter R,Heinecke A,Brämswig J,Dörffel W

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Most commonly a tissue diagnosis of rhabdomyosarcoma (RMS) in children is made by biopsy as opposed to primary resection. Open surgical procedures are often recommended to obtain sufficient material for accurate and complete diagnostic work up. Our institution has routinely used image-guided needle biopsies ...

journal_title：Pediatric blood & cancer

authors： Chowdhury T,Barnacle A,Haque S,Sebire N,Gibson S,Anderson J,Roebuck D

更新日期：2009-09-01 00:00:00