Assessment of Financial Burden as a Standard of Care in Pediatric Oncology.

abstract：BACKGROUND:Extramedullary infiltration (EMI) is an occasional clinical symptom in childhood acute myelogenous leukemia (AML), but there is considerable controversy regarding the prognostic significance of EMI in AML. PROCEDURE:We evaluated the frequency and prognostic significance of EMI at diagnosis of AML in childre...

journal_title：Pediatric blood & cancer

authors： Kobayashi R,Tawa A,Hanada R,Horibe K,Tsuchida M,Tsukimoto I,Japanese childhood AML cooperative study group.

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Neuroblastoma (NB) is cytogenetically characterized by a number of non-random events. However, knowledge is limited concerning the timing of occurrence and inter-action of many of these events. METHODS:Karyotypic patterns were obtained from a study group of 49 NB tumors that had been analyzed by conventiona...

journal_title：Pediatric blood & cancer

authors： Betts DR,Cohen N,Leibundgut KE,Kühne T,Caflisch U,Greiner J,Traktenbrot L,Niggli FK

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVES:Cancer-related pain in children is prevalent and undermanaged. Mobile health (mHealth) applications provide a promising avenue to address the gap in pain management in children with cancer. Pain Buddy is a multicomponent mHealth application developed to manage cancer-related pain in children. The goal of thi...

journal_title：Pediatric blood & cancer

authors： Hunter JF,Acevedo AM,Gago-Masague S,Kain A,Yun C,Torno L,Jenkins BN,Fortier MA

更新日期：2020-10-01 00:00:00

abstract：:Non-Hodgkin lymphoma (NHL) is a heterogeneous group of lymphoid malignancies with high incidence in adolescents and young adults (AYAs). The most common diseases include diffuse large B-cell lymphoma, anaplastic large cell lymphoma, Burkitt lymphoma, lymphoblastic lymphoma, and primary mediastinal large B-cell lymphom...

journal_title：Pediatric blood & cancer

authors： Hochberg J,Flower A,Brugieres L,Cairo MS

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:The combined inhibition of insulin-growth factor type 1 receptor (IGF-1R) and the mammalian target of rapamycin (mTOR) has shown activity in preclinical models of pediatric sarcoma and in adult sarcoma patients. We evaluated the activity of the anti-IGF-1R antibody cixutumumab with the mTOR inhibitor temsiro...

journal_title：Pediatric blood & cancer

authors： Wagner LM,Fouladi M,Ahmed A,Krailo MD,Weigel B,DuBois SG,Doyle LA,Chen H,Blaney SM

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Irinotecan is highly active against rhabdomyosarcoma (RMS), yet its tolerability and efficacy in combination with radiation is unknown. We examined local control and toxicities in RMS patients treated with radiotherapy (RT) in combination with radiosensitizing agents irinotecan + carboplatin (I + C). PROCED...

journal_title：Pediatric blood & cancer

authors： Dharmarajan KV,Wexler LH,Wolden SL

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Clinical characteristics and optimal treatment strategies for spindle cell/sclerosing rhabdomyosarcoma (ssRMS) have not been well established because of its rarity. PROCEDURE:Retrospective re-evaluation of sarcoma specimens (1997-2014) identified 16 ssRMSs (median age 20 years, range 7-39 years). Clinicopat...

journal_title：Pediatric blood & cancer

authors： Yasui N,Yoshida A,Kawamoto H,Yonemori K,Hosono A,Kawai A

更新日期：2015-06-01 00:00:00

abstract：:Leydig cell tumors account for 3% of testicular tumors and have never been reported after treatment for Ewing's sarcoma. We report the unusual occurrence of a patient who developed a Leydig cell tumor of the testis 18 years after successful treatment for Ewing's sarcoma. Additional monitoring for second malignancies m...

journal_title：Pediatric blood & cancer

authors： Butros LJ,Phillip S,Chou A,Meyers PA,Huvos AG,Healey JH,Russo P,Gorlick RG

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Severe congenital neutropenia is a rare disease, and autosomal dominantly inherited ELANE mutation is the most frequently observed genetic defect in the registries from North America and Western Europe. However, in eastern countries where consanguineous marriages are common, autosomal recessive forms might b...

journal_title：Pediatric blood & cancer

authors： Yılmaz Karapınar D,Patıroğlu T,Metin A,Çalışkan Ü,Celkan T,Yılmaz B,Karakaş Z,Karapınar TH,Akıncı B,Özkınay F,Onay H,Yeşilipek MA,Akar HH,Tüysüz G,Tokgöz H,Özdemir GN,Aslan Kıykım A,Karaman S,Kılınç Y,Oymak Y,Küpe

更新日期：2019-10-01 00:00:00

abstract：:Acute immune thrombocytopenic purpura (ITP) occurs most commonly in young children who present with severe isolated thrombocytopenia and purpura. A marrow examination is not required unless glucocorticoids are used, lest treatment mask incipient acute lymphoblastic leukemia, but controversy exists here. The recommenda...

journal_title：Pediatric blood & cancer

authors： Segel GB,Feig SA

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Children treated with cranial radiotherapy (CRT) for leukemia are at risk of developing central nervous system injuries. Magnetic resonance imaging (MRI) represents the examination method of choice for evaluating radiation-induced brain complications. The purpose of this report is to describe the spectrum of...

journal_title：Pediatric blood & cancer

authors： Faraci M,Morana G,Bagnasco F,Barra S,Polo P,Hanau G,Fioredda F,Caruso S,Rossi A,Spaziante R,Haupt R

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Children with hepatoblastoma (HB) are at risk of sarcopenia due to immobility, chemotherapy, and malnutrition. We hypothesized that children with HB have a low preoperative total psoas muscle area (tPMA), reflecting sarcopenia, which negatively impacts outcome. PROCEDURE:Retrospective study of children (1-1...

journal_title：Pediatric blood & cancer

authors： Ritz A,Kolorz J,Hubertus J,Ley-Zaporozhan J,von Schweinitz D,Koletzko S,Häberle B,Schmid I,Kappler R,Berger M,Lurz E

更新日期：2021-01-12 00:00:00

abstract：BACKGROUND:A potential long-term complication of central venous catheter (CVC)-related deep vein thrombosis (DVT), both symptomatic and asymptomatic, is development of post-thrombotic syndrome (PTS) characterized by persistent pain, swelling, and skin changes. Signs and symptoms of PTS were reported after CVC removal. ...

journal_title：Pediatric blood & cancer

authors： Revel-Vilk S,Menahem M,Stoffer C,Weintraub M

更新日期：2010-07-15 00:00:00

abstract：BACKGROUND:MOPP (mechlorethamine, vincristine, procarbazine, prednisone) and ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) are effective therapies for Hodgkin disease (HD) that may cause long-term toxicities in children. APE (cytosine arabinoside, cisplatin, etoposide) is a non-cross-resistant regimen wit...

journal_title：Pediatric blood & cancer

authors： Wimmer RS,Chauvenet AR,London WB,Villaluna D,de Alarcon PA,Schwartz CL

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:The median age of patients with Ewing sarcoma (EwS) at diagnosis is around 14-15 years. Older age is associated with a worse outcome. The correlation of age at diagnosis on sites of disease has not been fully described. OBJECTIVE:The goal of this study was to evaluate the differences in sites of primary tum...

journal_title：Pediatric blood & cancer

authors： Worch J,Ranft A,DuBois SG,Paulussen M,Juergens H,Dirksen U

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:The optimal dose and schedule of mycophenolate mofetil (MMF) in pediatric allogeneic stem cell transplant recipients remains to be determined. We previously reported safety and pharmacokinetics of MMF at 900 mg/m2 q6h dosing. This study was conducted to investigate the efficacy of tacrolimus plus q8h MMF dos...

journal_title：Pediatric blood & cancer

authors： Militano O,Ozkaynak MF,Mehta B,van deVen C,Hamby C,Cairo MS

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Over the past decade, PET-CT has been used to assess rhabdomyosarcoma (RMS) in children. However, the role of PET-CT in staging RMS is unknown. PROCEDURE:Thirty subjects with RMS, median age 7.3 years, underwent PET-CT before therapy. PET-CTs and conventional imaging (CI) were independently reviewed by two ...

journal_title：Pediatric blood & cancer

authors： Federico SM,Spunt SL,Krasin MJ,Billup CA,Wu J,Shulkin B,Mandell G,McCarville MB

更新日期：2013-07-01 00:00:00

abstract：:To assess safety and tolerability, we administered valacyclovir, an oral anti-viral medication that inhibits erythrocyte sickling in vitro, to 14 subjects with sickle-cell anemia for 1 week at a standard dose of 1,000 mg every 8 hr. No clinically significant adverse effects occurred. In 11 subjects in steady state, th...

journal_title：Pediatric blood & cancer

authors： Ender KL,DeBellis RH,Erlanger BF,Billote GB,Brittenham GM

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:We examined patterns of failure in pediatric patients with thoracic sarcoma and pulmonary metastases treated with intensity-modulated radiation therapy with dose-painting (DP-IMRT). PROCEDURE:Eleven pediatric patients, five with Ewing sarcoma family tumors (ESFT) and six with rhabdomyosarcoma (RMS), with pr...

journal_title：Pediatric blood & cancer

authors： Yang JC,Wexler LH,Meyers PA,Happersett L,La Quaglia MP,Wolden SL

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Subspecialty-specific normative values for clinical productivity of practicing pediatric hematologist/oncologists have not been well established. This information could be a useful adjunct in administrative decision-making in areas such as necessary levels of physician staffing and development of compensatio...

journal_title：Pediatric blood & cancer

authors： Griffin TC,Hutter JJ,Johnson KK,Moscow JA

更新日期：2004-08-01 00:00:00

abstract：:For many children with cancer, participation in oncology camp programs is an important component of healing that offers opportunities for fun and can have substantial impacts on social and physical well-being. Optimal medical care and infectious screening for children attending oncology camp is critical to maximize sa...

journal_title：Pediatric blood & cancer

authors： Alexander S,Science M,Breakey V,Clarke A,Gibson P

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:The role of the neutropenic diet in the development of infections in oncology and stem cell transplant (SCT) patients is controversial. There is no data on the use of the neutropenic diet among pediatric oncologists. METHODS:A self-administered electronic survey was sent to 1,639 pediatric oncologists at 19...

journal_title：Pediatric blood & cancer

authors： Braun LE,Chen H,Frangoul H

更新日期：2014-10-01 00:00:00

abstract：:The commonly accepted definition of Fanconi anemia (FA) relying on DNA repair deficiency is submitted to a critical review starting from the early reports pointing to mitomycin C bioactivation and to the toxicity mechanisms of diepoxybutane and a group of nitrogen mustards causing DNA crosslinks in FA cells. A critica...

journal_title：Pediatric blood & cancer

authors： Pagano G,d'Ischia M,Pallardó FV

更新日期：2015-07-01 00:00:00

abstract：:Under and overweight, usually secondary to energy imbalance, are common complications of childhood chronic disease. A simple energy balance paradigm has been helpful in understanding the etiology of underweight and overweight in chronic disease, including malignant disease, particularly when measurements of total ener...

journal_title：Pediatric blood & cancer

authors： Reilly JJ

更新日期：2008-02-01 00:00:00

abstract：:Melanotic neuroectodermal tumor of infancy (MNTI) is a rare tumor arising mainly in the orofacial bones. Among more than 200 cases described in articles, only seven cases involved orbital regions. We present a case of newborn with recurrent MNTI in the lateral wall of right orbit. The patient underwent complete surgic...

journal_title：Pediatric blood & cancer

authors： Nakanishi K,Hori H,Matsubara T,Matsuda K,Deguchi T,Komada Y

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Veno-occlusive disease (VOD) is a major complication following hematopoietic stem cell transplantation (HSCT). Its diagnosis is based on clinical criteria, which have a limited sensitivity. Increased plasminogen activator inhibitor-1 (PAI-1) levels have been suggested as a marker of VOD. We aimed to prospect...

journal_title：Pediatric blood & cancer

authors： Sartori MT,Cesaro S,Peruzzo M,Messina C,Saggiorato G,Calore E,Pillon M,Varotto S,Spiezia L,Cella G

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Alvespimycin (17-DMAG, KOS-1022), a potent small-molecule inhibitor of the protein chaperone Hsp90, is being developed as an anticancer agent because of the multiple Hsp90 client proteins involved in cancer cell growth and survival. PROCEDURES:Alvespimycin was tested against the in vitro panel of the Pediat...

journal_title：Pediatric blood & cancer

authors： Smith MA,Morton CL,Phelps DA,Kolb EA,Lock R,Carol H,Reynolds CP,Maris JM,Keir ST,Wu J,Houghton PJ

更新日期：2008-07-01 00:00:00

abstract：:We evaluated the in vitro glucocorticoid (GC) responsiveness of 117 pediatric acute myeloid leukemia cells by considering GC resistance, GC-induced proliferation, and GC-induced differentiation. None of the samples was highly GC sensitive, and only 15% were intermediately sensitive. GC-induced differentiation was not ...

journal_title：Pediatric blood & cancer

authors： Klein K,Haarman EG,de Haas V,Zwaan ChM,Creutzig U,Kaspers GL

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Children and adolescents with Non-Hodgkin lymphoma (NHL) and mature B-cell leukemia (B-ALL) have an excellent prognosis with contemporary chemotherapy stratified according to the histologic subtype and clinical stage of disease. However, a small subset of patients does not respond to front-line therapy or su...

journal_title：Pediatric blood & cancer

authors： Attarbaschi A,Dworzak M,Steiner M,Urban C,Fink FM,Reiter A,Gadner H,Mann G

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:This study aimed to compare the health related quality of life (HRQoL) of children and adolescents after malignant bone tumor surgery of the leg with healthy controls. PROCEDURE:Patients between 8 and 25 years old were cross-sectional recruited. Patients under 16 years of age received the TNO (Netherlands O...

journal_title：Pediatric blood & cancer

authors： Bekkering WP,Vliet Vlieland TP,Koopman HM,Schaap GR,Schreuder HW,Beishuizen A,Tissing WJ,Hoogerbrugge PM,Anninga JK,Taminiau AH

更新日期：2010-05-01 00:00:00