Clinicopathologic analysis of spindle cell/sclerosing rhabdomyosarcoma.

abstract：:Non-Hodgkin lymphoma (NHL) is a heterogeneous group of lymphoid malignancies with high incidence in adolescents and young adults (AYAs). The most common diseases include diffuse large B-cell lymphoma, anaplastic large cell lymphoma, Burkitt lymphoma, lymphoblastic lymphoma, and primary mediastinal large B-cell lymphom...

journal_title：Pediatric blood & cancer

authors： Hochberg J,Flower A,Brugieres L,Cairo MS

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Although screening for familial retinoblastoma has been shown to be beneficial we suspected that such screening programs may be less than optimal in developing countries (DC). METHODS:Retrospective cohort study comparing patients with familial retinoblastoma from five centers in DC (Argentina, Brazil, Turke...

journal_title：Pediatric blood & cancer

authors： Chantada GL,Dunkel IJ,Qaddoumi I,Antoneli CB,Totah A,Canturk S,Nawaiseh I,Fandiño A,Pífano I,Peksayar G,Ribeiro KB,Abramson DH

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Approximately one-third of patients with osteosarcoma who have a complete response to their initial treatment can be expected to relapse. It is important to define what host, tumor, or treatment characteristics determine outcome after relapse. We present findings in 59 patients treated at our institution fro...

journal_title：Pediatric blood & cancer

authors： Crompton BD,Goldsby RE,Weinberg VK,Feren R,O'Donnell RJ,Ablin AR

更新日期：2006-09-01 00:00:00

abstract：:Wilms tumor (WT) is the most common primary renal tumor in childhood. The occurrence of WT in patients with growth retardation, mental retardation and central nervous system abnormalities in association with premature chromatid separation (PCS) and mosaic variegated aneuploidy has been previously described in only 10 ...

journal_title：Pediatric blood & cancer

authors： Sari N,Akyuz C,Aktas D,Gumruk F,Orhan D,Alikasifoglu M,Aydin B,Alanay Y,Buyukpamukcu M

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:M6620 is a novel inhibitor of the DNA damage repair enzyme ATR, and has potentiated the activity of cisplatin and irinotecan in non-small cell lung cancer and colon cancer xenografts, respectively. PROCEDURES:M6620 was tested in vitro at concentrations ranging from 1.0 nM to 10.0 μM and at 75 nM in combinat...

journal_title：Pediatric blood & cancer

authors： Kurmasheva RT,Kurmashev D,Reynolds CP,Kang M,Wu J,Houghton PJ,Smith MA

更新日期：2018-02-01 00:00:00

abstract：:Malignant melanoma is rare in childhood and has never been reported to cause pancytopenia due to bone marrow metastases in a child. We report a 3-year-old boy with a large congenital melanocytic nevus who presented with bone pain and pancytopenia due to diffuse bone and bone marrow infiltration with metastatic melanom...

journal_title：Pediatric blood & cancer

authors： Spiller SE,Hawkins DS,Finn LS,Sze RW,Sybert V

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Right hemicolectomy (RHC) in patients with neuroendocrine tumors (NET) of the appendix has been advocated for tumors more than 2 cm, or with mesoappendix/vessel invasion, or with raised mitotic activity. No study demonstrated prolonged survival with RHC over appendectomy alone. The aim of this study was to c...

journal_title：Pediatric blood & cancer

authors： de Lambert G,Lardy H,Martelli H,Orbach D,Gauthier F,Guérin F

更新日期：2016-04-01 00:00:00

abstract：:The majority of children with cancer live in low- and middle-income countries (LMICs) with little or no access to cancer treatment. The purpose of the paper is to describe the current status of childhood cancer treatment in Africa, as documented in publications, dedicated websites and information collected through sur...

journal_title：Pediatric blood & cancer

authors： Kruger M,Hendricks M,Davidson A,Stefan CD,van Eyssen AL,Uys R,van Zyl A,Hesseling P

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Little is known about the effects of chemotherapy on patient antibody titers to vaccine-preventable infectious diseases; thus, there is no standard protocol for revaccinating post-chemotherapy patients. PROCEDURES:To assess losses of detectable antibody titers due to chemotherapy, we retrospectively examine...

journal_title：Pediatric blood & cancer

authors： Yu J,Chou AJ,Lennox A,Kleiman P,Wexler LH,Meyers PA,Gorlick R

更新日期：2007-10-15 00:00:00

abstract：BACKGROUND:Positron emission tomography (PET) and gallium scans facilitate diagnosis and staging, evaluation of response to therapy, and monitoring for relapse in Hodgkin lymphoma (HL), but have not been compared in pediatric HL. PROCEDURE:We performed concurrent PET and gallium scans on 44 pediatric HL patients at di...

journal_title：Pediatric blood & cancer

authors： Hines-Thomas M,Kaste SC,Hudson MM,Howard SC,Liu WA,Wu J,Kun LE,Shulkin BL,Krasin MJ,Metzger ML

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:The views and clinical practice of children's cancer units were surveyed regarding management of central venous catheter (CVC) occlusion (CVC-occlusion), CVC-related thrombosis (CVC-thrombosis) and thromboembolism (CVC-thromboembolism). PROCEDURE:A questionnaire was sent to all 22 United Kingdom Children's ...

journal_title：Pediatric blood & cancer

authors： Skinner R,Koller K,McIntosh N,McCarthy A,Pizer B,United Kingdom Children's Cancer Study Group (UKCCSG).,Paediatric Oncology Nursing Forum (PONF) Supportive Care Group.

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Central nervous system (CNS) malignancies are the most common solid tumors among children, and novel therapies are needed to help improve survival. Pomalidomide is an immunomodulatory agent that displays antiangiogenic and cytotoxic activity, making it an appropriate candidate to explore in pediatric CNS tum...

journal_title：Pediatric blood & cancer

authors： Fangusaro J,Mitchell DA,Kocak M,Robinson GW,Baxter PA,Hwang EI,Huang J,Onar-Thomas A,Dunkel IJ,Fouladi M,Warren KE

更新日期：2021-02-01 00:00:00

abstract：:A 12-year-old boy in third remission of an acute lymphoblastic leukaemia developed infection of lung and paranasal sinuses with Aspergillus flavus in neutropenia. Because of the high risk of leukaemia-relapse bone marrow transplantation (BMT) from a matched unrelated donor was carried out despite invasive pulmonary as...

journal_title：Pediatric blood & cancer

authors： Schuster F,Moelter C,Schmid I,Graubner UB,Kammer B,Belohradsky BH,Führer M

更新日期：2005-06-15 00:00:00

abstract：:Ependymoblastoma (EBL) is a rare malignant CNS tumor of early childhood, listed as a subgroup of primitive neuroectodermal tumors (PNET) in the 2007 WHO Classification of Tumours of the Central Nervous System. Histologically, EBL can be defined by multilayered, mitotically active "ependymoblastic" rosettes with centra...

journal_title：Pediatric blood & cancer

authors： Nowak J,Seidel C,Pietsch T,Friedrich C,von Hoff K,Rutkowski S,Warmuth-Metz M

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Few studies have addressed the efficacy of palliative radiotherapy (RT) for pediatric osteosarcoma (OS), a disease generally considered to be radioresistant. We describe symptom relief, local control, and toxicity associated with palliative RT among children with OS. PROCEDURE:Patients diagnosed with OS at ...

journal_title：Pediatric blood & cancer

authors： Chen EL,Yoo CH,Gutkin PM,Merriott DJ,Avedian RS,Steffner RJ,Spunt SL,Pribnow AK,Million L,Donaldson SS,Hiniker SM

更新日期：2020-01-01 00:00:00

abstract：:The efficacy of hydroxyurea in hemoglobin SC (HbSC) patients is not well documented. We describe the long-term response to hydroxyurea in children with clinically severe HbSC. In 15 patients, hydroxyurea resulted in a significant increase in mean corpuscular volume (MCV) and fetal hemoglobin (HbF) and a significant de...

journal_title：Pediatric blood & cancer

authors： Yates AM,Dedeken L,Smeltzer MP,Lebensburger JD,Wang WC,Robitaille N

更新日期：2013-02-01 00:00:00

abstract：:Progress has been made in resource-limited countries in treating acute lymphoblastic leukemia, but advances in solid malignancies have been slower. Multidisciplinary care coordination is challenging, assessing adherence to guidelines through quality improvement initiatives is essential. We characterized deviations fro...

journal_title：Pediatric blood & cancer

authors： Power-Hays A,Friedrich P,Fernandez G,Cruz NA,Marcus K,Rodriguez-Galindo C,Collado L

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Childhood acute lymphoblastic leukemia (ALL) survivors' increased risk for adverse health outcomes could be mitigated through consuming a balanced diet. Nonetheless, >70% of adult survivors do not meet survivorship dietary recommendations. ALL treatment may amplify risk for restricted dietary preferences (pi...

journal_title：Pediatric blood & cancer

authors： Chardon ML,Pinto S,Slayton WB,Fisher RS,Janicke DM

更新日期：2020-12-31 00:00:00

abstract：:Severe congenital neutropenia (SCN) is a bone marrow failure disease with an autosomal dominant inheritance from mutations in ELANE. Here, we report a 7-week-old Korean male with SCN. His elder sister died from pneumonia at 2 years. Direct sequencing of ELANE in the proband identified a heterozygous novel frameshift m...

journal_title：Pediatric blood & cancer

authors： Kim HJ,Song MJ,Lee KO,Kim SH,Kim HJ

更新日期：2015-12-01 00:00:00

abstract：:High dose acetaminophen (HDAC) with N-acetylcysteine (NAC) has been effective in adults with advanced malignancies. We report HDAC with NAC in a child with progressive hepatoblastoma, confirmed at biopsy of an unresectable hepatic mass. Alpha-fetoprotein (AFP) increased despite four courses of doxorubicin and one cour...

journal_title：Pediatric blood & cancer

authors： Kobrinsky NL,Sjolander DE,Goldenberg JA,Ortmeier TC

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Cisplatin (CDDP) ototoxicity is a significant side effect of the current treatment of medulloblastoma (MB). Cumulative dose of CDDP and age are recognized risk factors for hearing loss, but inter-individual susceptibility limits our ability to identify patients at risk for hearing loss. We describe the kinet...

journal_title：Pediatric blood & cancer

authors： Lafay-Cousin L,Purdy E,Huang A,Cushing SL,Papaioannou V,Nettel-Aguirre A,Bouffet E

更新日期：2013-02-01 00:00:00

abstract：:Torsades de Pointes (TdP) is a life-threatening ventricular arrhythmia that can be associated with metabolic abnormalities, exposure to arrhythmogenic medications, and congenital long-QT syndrome. This report describes a patient with ALL and multiple complications of therapy who developed TdP. The patient had no evide...

journal_title：Pediatric blood & cancer

authors： Bagatell R,Hainstock M,Lowe MC,Barber BJ,Samson RA

更新日期：2007-12-01 00:00:00

abstract：:Bereaved families fear their child being forgotten by those who knew their loved child, including their child's oncology team. Thoughtfully timed, family-centric condolences shared by pediatric oncology team members have the potential to extend our compassion and kindness toward a family during the darkness of grief. ...

journal_title：Pediatric blood & cancer

authors： Weaver MS,Lichtenthal WG,Larson K,Wiener L

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:The Paediatric Oncology Centres (POCs) treating childhood cancer in South East England produce unified supportive care guidelines for use in the secondary pediatric (shared care) units. This study evaluated the adherence to current guidelines for febrile neutropenia (FN) and documented outcome in terms of ba...

journal_title：Pediatric blood & cancer

authors： Duncan C,Chisholm JC,Freeman S,Riley U,Sharland M,Pritchard-Jones K

更新日期：2007-10-15 00:00:00

abstract：BACKGROUND:To investigate the incidence, clinical characteristics and survival of malignant tumours of the gastrointestinal tract in children in the West Midlands in Britain over a 44-year span time, to identify any change over this period and to compare the data with the world literature. PROCEDURE:Retrospective popu...

journal_title：Pediatric blood & cancer

authors： Hameed R,Parkes S,Davies P,Morland BJ

更新日期：2004-09-01 00:00:00

abstract：:MIRAGE syndrome caused by mutations in SAMD9 is associated with potential loss of chromosome 7 (-7/7q-) and an increased risk to develop myelodysplastic syndrome (MDS). We report a case of MIRAGE syndrome, caused by a novel SAMD9 mutation p.Leu641Pro, leading to characteristic clinical features as well as to the coexi...

journal_title：Pediatric blood & cancer

authors： Csillag B,Ilencikova D,Meissl M,Webersinke G,Laccone F,Narumi S,Haas O,Duba HC

更新日期：2019-04-01 00:00:00

abstract：:Anaplastic oligodendroglioma (AO) is rare in children. Treatment typically consists of varying combinations of surgery, chemotherapy, and radiotherapy. We present a pediatric case of frontal lobe AO with periventricular subcallosal extension and local leptomeningeal involvement. The isocitrate dehydrogenase (IDH) wild...

journal_title：Pediatric blood & cancer

authors： Sorge C,Li R,Singh S,Reddy AT,Solomon DA,Perry A,Friedman GK

更新日期：2017-12-01 00:00:00

abstract：:The incidence of bone marrow metastasis (BMM) in newly diagnosed Ewing sarcoma (ES) is variable across studies. An optimal staging strategy for detecting BMM is not defined. While bone marrow (BM) biopsy and/or aspirate (BMBA) have been the gold standard, [F-18]fluorodeoxyglucose positron emission tomography (FDG-PET)...

journal_title：Pediatric blood & cancer

authors： Campbell KM,Shulman DS,Grier HE,DuBois SG

更新日期：2021-02-01 00:00:00

abstract：PURPOSE:To evaluate and compare psychological distress in long-term survivors of solid tumors diagnosed in childhood and their siblings, and to identify significant correlates of psychological distress. PROCEDURE:Adult survivors (2,778) of solid tumors diagnosed in childhood and 2,925 siblings completed a long-term fo...

journal_title：Pediatric blood & cancer

authors： Zebrack BJ,Zevon MA,Turk N,Nagarajan R,Whitton J,Robison LL,Zeltzer LK

更新日期：2007-07-01 00:00:00

abstract：:Twenty-eight patients were maintained on subcutaneous immunoglobulin replacement for persistent B-cell aplasia and agammaglobulinemia following CD19-targeted chimeric antigen receptor T-cell therapy for B-cell lymphoblastic leukemia. Patients were transitioned from intravenous to subcutaneous immunoglobulin replacemen...

journal_title：Pediatric blood & cancer

authors： Arnold DE,Maude SL,Callahan CA,DiNofia AM,Grupp SA,Heimall JR

更新日期：2020-03-01 00:00:00