Abstract:
:In an ongoing investigation of compounds from natural products that exhibit anti-aging properties, hydroxyhibiscone A (1), a new furanosesquiterpenoid, together with hibiscone D (2), was isolated from the root bark of Hibiscus syriacus. Utilizing UV, IR, NMR, and MS spectroscopic analyses, these chemical structures were revealed. Compounds 1 and 2 were found to possess significant anti-aging properties on the human neutrophil elastase (HNE) assay, exhibiting HNE inhibitory activities with IC50 values of 5.2 and 4.6 micronM, respectively.
journal_name
J Microbiol Biotechnoljournal_title
Journal of microbiology and biotechnologyauthors
Ryoo IJ,Yun BS,Lee IK,Kim YH,Lee IS,Ahn JS,Bae K,Yoo IDdoi
10.4014/jmb.1004.04028subject
Has Abstractpub_date
2010-08-01 00:00:00pages
1189-91issue
8eissn
1017-7825issn
1738-8872pii
JMB020-08-04journal_volume
20pub_type
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