Abstract：
INTRODUCTION:This study reports the antimicrobial effect of photodynamic therapy (PDT) combined with endodontic treatment in patients with necrotic pulp infected with microflora resistant to a previous antibiotic therapy. METHODS:Thirty anterior teeth from 21 patients with periapical lesions that had been treated with conventional endodontic treatment and antibiotic therapy were selected. Microbiological samples were taken (1) after accessing the root canal, (2) after endodontic therapy, and (3) after PDT. RESULTS:All the patients had at least 1 microorganism resistant to antibiotics. PDT used polyethylenimine chlorin(e6) as a photosensitizer and a diode laser as a light source (P = 40 mW, t = 4 minutes, E = 9.6 J). Endodontic therapy alone produced a significant reduction in numbers of microbial species but only 3 teeth were free of bacteria, whereas the combination of endodontic therapy with PDT eliminated all drug-resistant species and all teeth were bacteria-free. CONCLUSIONS:The use of PDT added to conventional endodontic treatment leads to a further major reduction of microbial load. PDT is an efficient treatment to kill multi-drug resistant microorganisms.
journal_name
J Endodjournal_title
Journal of endodonticsauthors
Garcez AS,Nuñez SC,Hamblim MR,Suzuki H,Ribeiro MSdoi
10.1016/j.joen.2010.06.001subject
Has Abstractpub_date
2010-09-01 00:00:00pages
1463-6issue
9eissn
0099-2399issn
1878-3554pii
S0099-2399(10)00504-2journal_volume
36pub_type
临床试验,杂志文章abstract：INTRODUCTION:This study aimed to evaluate the frequency of dentinal microcracks observed after root canal preparation with 2 reciprocating and a conventional full-sequence rotary system using micro-computed tomographic analysis. METHODS:Thirty mesial roots of mandibular molars presenting a type II Vertucci canal confi...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2014.02.019
更新日期：2014-09-01 00:00:00
abstract：INTRODUCTION:The aim of this study was to evaluate the effects of different curing units and 2 luting cements on the push-out bond strength of a translucent fiber post. METHODS:Thirty maxillary incisor roots were endodontically treated. Post spaces were prepared, and the smear layers were removed. Posts (FRC Postec Pl...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2010.04.026
更新日期：2010-09-01 00:00:00
abstract：:A case study is presented that described an acute flare-up of a tooth following a vital bleaching procedure. The case illustrates (a) the importance of assessing the pulpal and periradicular status of a tooth prior to any vital bleaching procedure; and (b) the alteration of the local adaptation syndrome by the bleachi...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(06)80488-7
更新日期：1992-07-01 00:00:00
abstract：INTRODUCTION:Calcium hydroxide (Ca[OH]2) is a widely used interappointment dressing, but its antibacterial property is compromised by dentin. Hence, the addition of chlorhexidine (CHX) with Ca(OH)2 has been proposed. However, the antimicrobial efficacy of this mixture compared with Ca(OH)2 alone is currently still deba...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2016.01.020
更新日期：2016-05-01 00:00:00
abstract：INTRODUCTION:The aim of this study was to investigate the potential of autologous mesenchymal bone marrow stem cells (BMSCs) to promote hard-tissue formation after direct pulp capping procedures. MATERIALS AND METHODS:Bone marrow was aspirated from the iliac crest of healthy dogs of nonspecific race. Mononuclear cells...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2012.12.012
更新日期：2013-05-01 00:00:00
abstract：:The effects of various cleaning, chemical disinfection, and sterilization procedures on the cutting efficiency of endodontic instruments Unifile (De Trey, Bois Colombes, France), (Flexofile Maillefer, Ballaigues, Switzerland), and H-File (Maillefer)) were investigated. The cross-infection control treatment procedures ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(96)80059-8
更新日期：1996-12-01 00:00:00
abstract：:The role of T-cells in the development of periapical lesions was investigated immunohistochemically using 16 normal (BALB/c) mice and 16 nude (BALB/c nu/nu) mice (congenitally T-cell-deficient mice). The pulp chambers of maxillar first molars of all mice were opened, and the infiltrated immunocytes (anti-Thy1.2, -Lyt-...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/s0099-2399(06)80565-0
更新日期：1995-04-01 00:00:00
abstract：INTRODUCTION:This study aimed to investigate dental pulp responses to novel bioactive glass (BG) pulp capping materials after direct pulp capping in vivo. METHODS:Novel BG pulp capping materials are composed of powder and fluid. The powder is BG (82.36% SiO2, 15.36% CaO, and 2.28% P2O5), and the fluid is provided in 2...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2017.03.011
更新日期：2017-10-01 00:00:00
abstract：INTRODUCTION:Bleeding control is an important aspect in endodontic surgery. Two hemostatic techniques were compared with regard to their efficacy to bleeding control in endodontic surgery. METHODS:A randomized, 2-arm, parallel pilot study involving 30 patients with periradicular lesions was performed including the fol...
journal_title：Journal of endodontics
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.joen.2019.04.011
更新日期：2019-08-01 00:00:00
abstract：INTRODUCTION:Apical surgery is frequently indicated in maxillary first molars. Occasionally, a vascular anastomosis in the lateral maxillary sinus wall can be observed during surgery. The aim of this study was to examine the distance between the vascular bone channel (VBC) and the root apices of maxillary first molars ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2019.09.004
更新日期：2019-12-01 00:00:00
abstract：:The aim of this in vitro study was to determine whether irrigation with apical negative pressure was more effective than traditional positive-pressure irrigation in eradicating Enterococcus faecalis from preshaped root canals. Fifty-four extracted mandibular molars were instrumented to produce either a non-tapered or ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2008.07.022
更新日期：2008-11-01 00:00:00
abstract：:This study evaluated the sealing ability of fast and regular set Super-EBA with different powder-to-liquid ratios as a root-end filling material. Fifty extracted maxillary central incisors were uniformly cleaned and shaped using a crown-down technique with Gates-Glidden drills and Profile series 29.04 taper rotary ins...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(99)80378-1
更新日期：1999-08-01 00:00:00
abstract：INTRODUCTION:Securing a reproducible glide path before instrumentation is recommended to maintain the original geometry of the root canal system and to prevent file separation. Mechanical glide path management systems have been introduced to expedite this step. The aim of this study was to compare apical transportation...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2015.07.014
更新日期：2015-11-01 00:00:00
abstract：INTRODUCTION:Long-term predictability of restored endodontically treated teeth is important for the decision of tooth retention versus extraction and implant placement. The purpose of this study was to validate the hypothesis that preoperative factors can predict the long-term prognosis of molars requiring endodontic a...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2010.10.005
更新日期：2011-01-01 00:00:00
abstract：INTRODUCTION:This study evaluated the cyclic fatigue resistance (CFR) of Reciproc (R25 and R40; VDW, Munich, Germany) and Reciproc Blue (R25 and R40, VDW) instruments used in an artificial S-shaped canal. METHODS:A total of 80 files were tested in an S-shaped canal (n = 20 for each file, Reciproc R25 and R40 and Recip...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2017.04.009
更新日期：2017-10-01 00:00:00
abstract：:Infection control guidelines recommend disinfection of extracted teeth in 10% formalin for 2 weeks before use. Although extracted teeth are routinely used for in vitro endodontic research, the potential influence of formalin has not been evaluated. The purpose of this study was to investigate the effect of formalin st...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2006.04.009
更新日期：2006-09-01 00:00:00
abstract：INTRODUCTION:The diagnosis and treatment planning of cracked teeth depend on the understanding of how cracks affect the surrounding tissues. This study evaluated the dentin and pulp conditions in teeth affected by cracks and attrition. METHODS:Specimens under investigation included 12 cracked posterior teeth and 8 tee...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2014.09.021
更新日期：2015-03-01 00:00:00
abstract：INTRODUCTION:We evaluated the radiopacity and antibacterial properties of various concentrations of double antibiotic paste (DAP) containing barium sulfate (BaSO4) or zirconium oxide (ZrO2) radiopaque agents. METHODS:The radiopacity of 1, 10, and 25 mg/mL DAP containing 30% (w/v) BaSO4 or ZrO2, DAP-free radiopaque pas...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2018.06.010
更新日期：2018-09-01 00:00:00
abstract：INTRODUCTION:It has been widely accepted that dental pulp stem cells (DPSCs), which are a class of self-renewal and differentiation potential of adult stem cells, play an important role in the repair procession of pulp's inflammation. We investigated whether tumor necrosis factor alpha (TNF-α) could induce the prolifer...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2015.02.020
更新日期：2015-07-01 00:00:00
abstract：:This study evaluated the effect of three post surface treatments on quartz-fiber post (a) retention and (b) morphology. A control group was not treated. Different treatments were performed for the other posts: silanization; etching by hydrofluoric acid 9.5%; sandblasting with 50 microm Al2O3. Two specimens of each gro...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2006.10.015
更新日期：2007-03-01 00:00:00
abstract：:The authors reviewed the literature evaluating the antibacterial effectiveness of intracanal medicaments used in the management of apical periodontitis. A PICO (problem, intervention, comparison, outcome) strategy was developed to identify studies dealing with calcium hydroxide, phenolic derivatives, iodine-potassium ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1097/01.don.0000129959.20011.ee
更新日期：2004-10-01 00:00:00
abstract：INTRODUCTION:Revascularization treatment is rapidly becoming an accepted treatment alternative for the management of endodontic pathology in immature permanent teeth with necrotic dental pulps. However, the success and timing of clinical resolution of symptoms, and radiographic outcomes of interest, such as continued h...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2014.08.023
更新日期：2014-12-01 00:00:00
abstract：:Dentin permeability and hypersensitivity are both reduced when the dentinal tubules are occluded. Previous scanning electron microscopic studies showed that Nd:YAG laser could cause melting of dentin and closure of exposed dentinal tubules without dentin surface cracking. Therefore, the aim of the present study was to...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(97)80403-7
更新日期：1997-11-01 00:00:00
abstract：INTRODUCTION:The mental foramen (MF) is an important landmark in dentistry. Knowledge of its position is central to perform block anesthesia of the mental nerve or to avoid nerve damage during surgical procedures in the premolar area of the mandible. The present radiographic study aimed at evaluating the location and d...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2013.07.033
更新日期：2013-12-01 00:00:00
abstract：INTRODUCTION:Complementary methods of anatomic diagnosis, including cone-beam computed tomographic (CBCT) imaging, may be useful in the diagnosis of mesiobuccal (MB) canals of maxillary molars. METHODS:Thirty-five maxillary first molars were subjected to ex vivo analysis and 4 CBCT protocols: i-CAT Classic (Imaging Sc...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2016.12.011
更新日期：2017-05-01 00:00:00
abstract：:Although many options are proposed for the treatment of cracked posterior teeth, most treatment decisions are not evidence based. Thus, considerable individual variation can occur regarding treatment recommendations for the same scenario. To our knowledge, there are no studies in the literature assessing practitioners...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2017.03.029
更新日期：2017-09-01 00:00:00
abstract：:The antibacterial activity of three commercial 10% carbamide peroxide bleaching agents (Nite White, Karisma, and Opalescence) on Streptococcus mutans, Streptococcus mitis, Streptococcus sanguis, Lactobacillus casei, and Lactobacillus acidophilus was examined. Chlorhexidine (0.2%) was used as a positive control. Test m...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(96)80217-2
更新日期：1996-07-01 00:00:00
abstract：:Extracanal invasive resorption is not a well-defined phenomenon. This article describes its clinical, radiographic, and histological characteristics. Treatment of affected teeth based on the location of the resorptive defect is also described. ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(98)80056-3
更新日期：1998-07-01 00:00:00
abstract：:Twenty volunteers with first molars free of restorations and caries were recruited. One molar from each arch was selected, and rubber dam was applied. Seven sites on each crown were electric pulp tested 4 times with an Elements Diagnostic Unit, and lowest threshold responses were recorded. Data were analyzed with one-...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2007.08.006
更新日期：2007-11-01 00:00:00
abstract：:In the present study, we investigated the effect of the addition of different grades of gum rosins and hydrogenated resins to Grossman cement on dimensional stability, solubility and disintegration. pH and conductivity, which may affect these properties, were also determined. The experiments were performed according t...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(99)80284-2
更新日期：1999-07-01 00:00:00
