Proteomics analysis of plasma membrane from liver sinusoidal endothelial cells after partial hepatectomy by an improved two-dimensional electrophoresis.

abstract：:Osteosarcoma (OS) is a type of malignant tumor arising from soft-tissues of bone and displays poor prognosis in most cases. However, the molecular mechanism by which OS initiates and progresses is still not completely elucidated. miR-155 has been shown to be overexpressed in OS specimen and cell lines. Our study is in...

journal_title：Molecular and cellular biochemistry

authors： Sun X,Geng X,Zhang J,Zhao H,Liu Y

更新日期：2015-05-01 00:00:00

abstract：:This comparative study investigates the relationship between sarcoplasmic reticulum (SR) calcium(Ca2+)-ATPase transport activity and phospholamban (PLB) phosphorylation in whole cardiac homogenates of spontaneously hypertensive rats (SHR) and their parent, normotensive Wistar Kyoto (WKY) strain during early postnatal ...

journal_title：Molecular and cellular biochemistry

authors： Freestone N,Singh J,Krause EG,Vetter R

更新日期：1996-10-01 00:00:00

abstract：:Incubation of Clone 9 cells, a nontransformed rat liver cell line, in the presence of 5 mM azide results in an induction of GLUT1 mRNA which becomes detectable after approximately 3 h of continuous exposure to the agent. In examining the role of on-going protein synthesis in this response, we found that: (i) the induc...

journal_title：Molecular and cellular biochemistry

authors： Behrooz A,Ismail-Beigi F

更新日期：1998-10-01 00:00:00

abstract：:It has been established that diabetes results in a cardiomyopathy, and increasing evidence suggests that an altered substrate supply and utilization by cardiac myocytes could be the primary injury in the pathogenesis of this specific heart muscle disease. For example, in diabetes, glucose utilization is insignificant,...

journal_title：Molecular and cellular biochemistry

authors： Rodrigues B,Cam MC,McNeill JH

更新日期：1998-03-01 00:00:00

abstract：:The incidence of anxiety-related diseases is increasing these days, hence there is a need to understand the mechanisms that underlie its nature and consequences. It is known that limbic structures, mainly the prefrontal cortex and amygdala, are involved in the processing of anxiety, and that projections from prefronta...

journal_title：Molecular and cellular biochemistry

authors： Mejia-Carmona GE,Gosselink KL,Pérez-Ishiwara G,Martínez-Martínez A

更新日期：2015-08-01 00:00:00

abstract：:Studies designed to examine effects of fat mass reduction (including lipodystrophy and lipectomy) on human serum total and LDL-cholesterol concentrations are inconsistent. The purpose of this study was to examine effect of partial lipectomy in rats (as an experimental model of fat mass reduction in humans) on (1) circ...

journal_title：Molecular and cellular biochemistry

authors： Dettlaff-Pokora A,Sucajtys-Szulc E,Sledzinski T

更新日期：2019-05-01 00:00:00

abstract：:The recombinant eukaryotic expression vector pCMV4-rmCGbeta, inserted full-length cDNA of the beta-subunit of rhesus monkey chorionic gonadotropin (rmCGbeta), as DNA immuno-contraceptive against CGbeta glycoprotein, has previously demonstrated the biological expression of rmCGbeta in vitro and in vivo. The plasmid DNA...

journal_title：Molecular and cellular biochemistry

authors： Chen Y,Liu Z,Yang Y,Chen YZ,Peng JP

更新日期：2002-02-01 00:00:00

abstract：:Concentrations of 1-4 mumol l-1 isoproterenol cause both in right ventricular papillary muscles and in enzymatically isolated myocytes of the guinea-pig a Ca2+ overload-induced state which is functionally characterized by biphasic (multiphasic) twitches and biphasic (multiphasic) intracellular calcium transients, resp...

journal_title：Molecular and cellular biochemistry

authors： Löhn M,Szymanski G,Markwardt F

更新日期：1996-07-01 00:00:00

abstract：:Cardiac failure is one of the leading causes of mortality in developed countries. As life expectancies of the populations of these countries grow, the number of patients suffering from cardiac insufficiency also increases. Effective treatments are being sought and recently a new class of drugs, the calcium sensitisers...

journal_title：Molecular and cellular biochemistry

authors： Sorsa T,Pollesello P,Solaro RJ

更新日期：2004-11-01 00:00:00

abstract：:Population data have consistently demonstrated a correlation between circulating branched-chain amino acids (BCAA) and insulin resistance. Most recently valine catabolite, 3-hydroxyisobutyrate, has emerged as a potential cause of BCAA-mediated insulin resistance; however, it is unclear if valine independently promotes...

journal_title：Molecular and cellular biochemistry

authors： Rivera ME,Lyon ES,Johnson MA,Sunderland KL,Vaughan RA

更新日期：2020-05-01 00:00:00

abstract：:Prion protein (PrP) interacts with some kringle domain-containing proteins. Kringle domains serve as binding domains in the interaction with PrP. The structural conservation among kringle domains leads to the hypothesis that any protein containing these domains can interact with PrP and be involved in prion pathogenes...

journal_title：Molecular and cellular biochemistry

authors： Kim Y,Song J,Mays CE,Titlow W,Yoon D,Ryou C

更新日期：2009-08-01 00:00:00

abstract：:To explore the effect of LYRM1 over-expression on basal and insulin-stimulated glucose uptake in rat skeletal muscle cells, and to understand the underlying mechanisms, Rat myoblasts (L6) transfected with either an empty expression vector (pcDNA3.1Myc/His B) or a LYRM1 expression vector were differentiated into myotub...

journal_title：Molecular and cellular biochemistry

authors： Kou C,Cao X,Qin D,Ji C,Zhu J,Zhang C,Zhu C,Gao C,Chen R,Guo X,Zhang M

更新日期：2011-02-01 00:00:00

abstract：:This study examined the role of the protein kinase C (PKC) signalling pathway in the regulation of expression of human complement factor I (CFI) gene. The production of CFI by Hep G2 cells was enhanced in a dose- and time-dependent fashion by 12-O-tetradecanoyl-1,2-phorbol 13-acetate (TPA), a potent PKC activator. 4Al...

journal_title：Molecular and cellular biochemistry

authors： Minta J,Fung M

更新日期：1999-11-01 00:00:00

abstract：:Enhancer of zeste homolog 2 (EZH2) is a highly conserved histone methyltransferase, which is overexpressed in different types of cancers such as breast and prostate cancer. It is reported that EZH2 can directly down-regulate RUNX3 by increasing histone H3 methylation. However, the role of EZH2 in the development and p...

journal_title：Molecular and cellular biochemistry

authors： Lian R,Ma H,Wu Z,Zhang G,Jiao L,Miao W,Jin Q,Li R,Chen P,Shi H,Yu W

更新日期：2018-02-01 00:00:00

abstract：:A matricellular protein, osteopontin (OPN), is expressed in response to mechanical stress and similar stimuli in the heart, integrates the inter-ECM signal transduction network of component cells, and maintains efficient contractility through quantitative and qualitative control of extracellular matrix (ECM) proteins....

journal_title：Molecular and cellular biochemistry

authors： Okamoto H

更新日期：2007-06-01 00:00:00

abstract：:The presence of a prostatic-like acid phosphatase is reported in human lactating milk. Its activity is associated with skim milk and it could be separated from the other acid phosphatases only after Triton X-100 treatment. By all the criteria applied, it appears to be very similar to prostatic acid phosphatase. An app...

journal_title：Molecular and cellular biochemistry

authors： Podhajcer OL,Filmus JE,Mordoh J

更新日期：1985-02-01 00:00:00

abstract：:Cardiac muscle-related microRNAs play important roles in cardiac development and disease by translational silencing of mRNAs, the dominant mechanism of microRNA action. To test whether they could be involved in daunorubicin-associated cardiomyopathy (DACM), we determined expression patterns of myomiRs in two distinct ...

journal_title：Molecular and cellular biochemistry

authors： Doka G,Malikova E,Galkova K,La Rocca G,Kruzliak P,Adamek M,Rodrigo L,Krenek P,Klimas J

更新日期：2017-08-01 00:00:00

abstract：:Failure in obtaining expression of functional adrenocorticotropic hormone receptor (ACTHR, or melanocortin 2 receptor, MC2R) in non-adrenal cells has hindered molecular analysis of ACTH signaling pathways. Here, we ectopically expressed the mouse ACTHR in Balb/c mouse 3T3 fibroblasts to analyze ACTH signaling pathways...

journal_title：Molecular and cellular biochemistry

authors： Forti FL,Dias MH,Armelin HA

更新日期：2006-12-01 00:00:00

abstract：:S-glutathionylation, the formation of mixed disulfides of glutathione with cysteine residues of proteins, is a broadly observed physiological modification that occurs in response to oxidative stress. Since cysteine residues are particularly susceptible to oxidative modification by reactive oxygen species, S-glutathion...

journal_title：Molecular and cellular biochemistry

authors： Leonberg AK,Chai YC

更新日期：2007-10-01 00:00:00

abstract：:The effect of Aclacinomycin B (ACM-B), an anthracycline antitumor antibiotic, on the DNA-dependent RNA synthesis using single- and double-stranded DNAs of known base content and sequence is studied. The data show that ACM-B effectively inhibits the double-stranded DNA-directed RNA synthesis with a preference of poly[d...

journal_title：Molecular and cellular biochemistry

authors： Li LH,Yu FL

更新日期：1989-10-05 00:00:00

abstract：:The occurrence of the 'whey' protein, alpha-lactalbumin, in pig (Sus scrofus) milk samples from 904 sows is examined. A semi-discontinuous buffer system has been developed to detect the existence of genetic polymorphism. There are two homozygous variants, designated A and B. Both variants are isolated and it is shown ...

journal_title：Molecular and cellular biochemistry

authors： Bell K,McKenzie HA,Shaw DC

更新日期：1981-03-13 00:00:00

abstract：:The genome sequence of Mycobacterium tuberculosis revealed the presence of several hydrolases involved in lipid metabolism including the members of Lip gene family. Rv0646c (LipG) is one of them. It is annotated as putative esterase/lipase because of the presence of consensus sequence 'GXSXG.' The gene was cloned, exp...

journal_title：Molecular and cellular biochemistry

authors： Rastogi R,Kumar A,Kaur J,Saini V,Kaur J,Bhatnagar A

更新日期：2018-10-01 00:00:00

abstract：:The regulation patterns of gastric acid secretion in rats were investigated. Pentagastrin and histamine stimulate gastric acid secretion, but the inhibitors of DNA-dependent synthesis of RNA and of proteins prevent only the pentagastrin action. It has been found that pentagastrin induces histidine decarboxylase in gas...

journal_title：Molecular and cellular biochemistry

authors： Salganik RI,Bersimbaev RI,Argutinskaya SV,Kiseleva EV,Khristolyubova NB,Deribas VI

更新日期：1976-09-30 00:00:00

abstract：:The formation of porphyrins from porphobilinogen by a duck blood hemolysate was examined. The system was found to form mainly protoporphyrin IX and hemin, and accumulated lesser amounts of uroporphyrins, hepatacarboxylic porphyrin, and coproporphyrins. By storage at -20 degrees the accumulation of uroporphyrins and he...

journal_title：Molecular and cellular biochemistry

authors： Frydman RB,Frydman B,Feinstein G

更新日期：1977-07-05 00:00:00

abstract：:Cytochrome P450 is known to cause carcinogen activation and correspondingly increased cancer risk in animal models. In order to determine whether P450 in the colon may be involved in cancer development in the human, the human colon cell line LS174T was examined for the presence of various cytochromes P450. Two isozyme...

journal_title：Molecular and cellular biochemistry

authors： White TB,Hammond DK,Vásquez H,Strobel HW

更新日期：1991-03-27 00:00:00

abstract：:The development of hypercholesterolemia is a multifactorial process in which elevated plasma cholesterol levels play a central role. This study analyzed the variability of the expression and activity of myosin light chain kinase (MLCK) and endothelial permeability in the artery wall of rabbits after feeding the animal...

journal_title：Molecular and cellular biochemistry

authors： Zhu HQ,Zhou Q,Jiang ZK,Gui SY,Wang Y

更新日期：2011-01-01 00:00:00

abstract：:Cancer stem cells (CSCs) are believed to be responsible for tumor metastasis, recurrence, and high mortality of cancer patients due to their high tumorigenicity resistance to chemo-radiotherapy. Morusin possesses anti-cancer activity through attenuation of NF-κB activity, which is up-regulated in cancer stem cells. Th...

journal_title：Molecular and cellular biochemistry

authors： Wang L,Guo H,Yang L,Dong L,Lin C,Zhang J,Lin P,Wang X

更新日期：2013-07-01 00:00:00

abstract：:The aim of this study was to investigate the interrelationship between the mitochondrial phospholipid cardiolipin (CL), mitochondrial respiration and morphology in dependence on hypoxia/reoxygenation and Ca(2+). Therefore, we subjected rat liver mitochondria to hypoxia/reoxygenation at different extramitochondrial Ca(...

journal_title：Molecular and cellular biochemistry

authors： Martens JC,Keilhoff G,Gardemann A,Schild L

更新日期：2014-09-01 00:00:00

abstract：:The normal translocation of nascent polypeptides into the lumen of the endoplasmic reticulum (ER) is thought to be aided in part by a translocon-associated protein (TRAP) complex consisting of 4 protein subunits. The association of mature proteins with the ER and Golgi, or other intracellular locales, such as lysosome...

journal_title：Molecular and cellular biochemistry

authors： Mangos S,Krawetz R,Kelly GM

更新日期：2000-12-01 00:00:00

abstract：:The regulation of the guinea-pig pancreatic acinar plasma membrane Ca2+ pump by protein kinase A, protein kinase C and calmodulin was investigated. The results were compared with the effects of these regulators on the high affinity Ca(2+)-ATPase found in this membrane preparation. The catalytic subunit of cyclic AMP-d...

journal_title：Molecular and cellular biochemistry

authors： Mahey R,Allen BG,Bridges MA,Katz S

更新日期：1992-06-26 00:00:00