Abstract：
:Children and adolescents with autistic spectrum disorders (ASD) suffer from sleep problems, particularly insomnia, at a higher rate than typically developing children, ranging from 40% to 80%. Sleep problems in ASD might occur as a result of complex interactions between biological, psychological, social/environmental, and family factors, including child rearing practices that are not conducive to good sleep. Interestingly, children with a history of developmental regression have a more disturbed sleep pattern than children without regression. Even though regulation of sleep in children with ASD is still poorly understood, circadian abnormalities in autism might be the result of genetic abnormalities related to melatonin synthesis and melatonin's role in modulating synaptic transmission. Recently a bifurcation of the sleep/wake cycle with increased sensitivity to external noise and short sleep duration causing irregular sleep onset and wake up times has been suggested. Identifying and treating sleep disorders may result not only in improved sleep, but also impact favorably on daytime behavior and family functioning. Several studies have also demonstrated effectiveness of behavioral interventions for sleep onset and maintenance problems in these populations. When behavioral interventions are not effective or lead only to a partial response, pharmacological treatment options should be considered. Studies of melatonin use in children with ASD provide evidence for its effectiveness and safety in the long run. The clinician assessing a child with an ASD should screen carefully for sleep disorders and make referrals as indicated.
journal_name
Sleep Medjournal_title
Sleep medicineauthors
Cortesi F,Giannotti F,Ivanenko A,Johnson Kdoi
10.1016/j.sleep.2010.01.010subject
Has Abstractpub_date
2010-08-01 00:00:00pages
659-64issue
7eissn
1389-9457issn
1878-5506pii
S1389-9457(10)00175-9journal_volume
11pub_type
杂志文章,评审相关文献
SLEEP MEDICINE文献大全abstract：OBJECTIVES:To determine the prevalence and correlates of help-seeking behaviors for insomnia in Hong Kong Chinese middle-aged adults and their offspring. METHODS:A total of 2231 middle-aged adults (54.2% females, mean age 45.8 years) and 2186 children and adolescents (51.9% females, mean age 13.4 years) completed a qu...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2016.01.006
更新日期：2016-05-01 00:00:00
abstract：OBJECTIVE:Children's sleep problems are associated with poorer student functioning in the school environment, including impairment in peer relationships; yet, no studies have examined sleep functioning in relation to the student-teacher relationship. The objective of this study was to examine whether child-rated total ...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2017.12.001
更新日期：2018-07-01 00:00:00
abstract：OBJECTIVES:The accuracy of respiratory polygraphy (RP) is limited because of the absence of electroencephalography (EEG). Pulse wave amplitude (PWA) reduction has been shown to be a marker of autonomic activation during arousal, and may represent a substitute for obstructive respiratory-related cortical arousal (RRCA)....
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2017.02.027
更新日期：2017-06-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Interventions to improve treatment outcomes in sleep apnoea-hypopnoea syndrome (SAHS) have had mixed success. Most have concentrated on following the use of a continuous positive airway pressure (CPAP) machines; poorer users may not return for machine readings, so any compliance study must take i...
journal_title：Sleep medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.sleep.2005.09.007
更新日期：2006-04-01 00:00:00
abstract：OBJECTIVE:The study objective was to evaluate the association between cervical spondylosis (CS) and a subsequent diagnosis of obstructive sleep apnea (OSA) in light of the expected constricting impact of CS-associated cervical spine changes on the pharyngeal airway space, a key contributor to OSA. METHODS:Data were re...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2020.03.025
更新日期：2020-07-01 00:00:00
abstract：OBJECTIVE:To create a sleep duration classification technique for waist-worn ActiGraph accelerometers in preschool-aged children. METHODS:Children wore ActiGraph wGT3X-BT accelerometers on their right hip for 7 days (24 h/day). Ground truth nap, sleep, and wake were estimated through visual inspection of accelerometer...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2020.12.019
更新日期：2021-01-08 00:00:00
abstract：OBJECTIVE:To provide normative values for sleep macroarchitecture of healthy children aged 1-18 years using the AASM sleep scoring criteria, assessing the effects of gender, age, and Tanner pubertal stage. METHODS:One-night polysomnography was performed at subjects' habitual bedtimes in 16 laboratories on 209 healthy ...
journal_title：Sleep medicine
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1016/j.sleep.2010.11.011
更新日期：2011-06-01 00:00:00
abstract：BACKGROUND AND AIM:Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) is associated with glucose dysmetabolism and insulin resistance, therefore the amelioration of breathing disturbances during sleep can allegedly modify the levels of markers of glucose regulation and insulin resistance, such as glycated hemoglobin, fa...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2008.10.004
更新日期：2009-09-01 00:00:00
abstract：:We describe five patients who presented with irresistible daytime sleepiness and who have the clinical and laboratory features of narcolepsy but differ from most patients with narcolepsy in their ability to resist falling asleep during the daytime. All of the patients described partial or complete remission of their s...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/s1389-9457(99)00016-7
更新日期：2000-04-01 00:00:00
abstract：:This chapter addresses the use of long-term non-invasive positive pressure ventilation (NIPPV) (to the exclusion of continuous positive airway pressure) in the different clinical settings in which it is currently proposed: principally in diseases responsible for hypoventilation characterized by elevated PaCO(2). Nasal...
journal_title：Sleep medicine
pub_type： 杂志文章,评审
doi：10.1016/j.sleep.2007.03.009
更新日期：2007-06-01 00:00:00
abstract：OBJECTIVES:To evaluate the efficacy and safety profile of gaboxadol, a selective extrasynaptic GABA(A) agonist (SEGA) previously in development for the treatment of insomnia. METHODS:This was a randomised, double-blind, placebo-controlled, parallel-group, 2-week, Phase III study of gaboxadol 5, 10 and 15mg in outpatie...
journal_title：Sleep medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.sleep.2008.09.010
更新日期：2009-08-01 00:00:00
abstract：OBJECTIVE:Eveningness tendency and insomnia are common in adolescents, but whether they have an independent or synergistic effect on the risk of psychopathology have remained undefined. The present study aimed to examine eveningness chronotype and insomnia symptoms in relation to mental health and emotional and behavio...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2018.03.025
更新日期：2018-07-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Patients with asthma often complain of daytime sleepiness, which is usually attributed to a direct effect of asthma on nocturnal sleep quality. We investigated this and other potential explanations for daytime sleepiness among asthmatics. PATIENTS AND METHODS:One hundred fifteen adult asthmatics...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2006.02.001
更新日期：2006-12-01 00:00:00
abstract：OBJECTIVE:We aimed to determine if selected genetic polymorphisms in the aryl hydrocarbon receptor (AHR)-signaling pathway and circadian locomotor output cycles kaput (CLOCK) are associated with insomnia and early awakening in middle-aged women. METHODS:Women aged 45 to 54years (n=639) were recruited into a middle-age...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2013.04.007
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to prospectively examine all patients with a diagnosis of RLS consulting a sleep disorders clinic and to assess RLS severity and augmentation and their associations, including ferritin levels. METHODS:Patients were stratified into patients with RLS as ancillary diagnosis, RLS suffer...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2008.09.007
更新日期：2009-06-01 00:00:00
abstract：OBJECTIVE:To assess the impact of three hypopnea definitions on the severity classification of obstructive sleep apnea (OSA) and its association with cardiovascular mortality risk in women and elderly individuals. METHODS:We analyzed two Spanish clinical cohorts (1116 women and 939 elderly individuals) who were studie...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2016.05.020
更新日期：2016-01-01 00:00:00
abstract：:Sixty-five years after the discovery of rapid eye movement (REM) sleep, the reasons why we sleep and why we need two states of sleep are still largely unclear. Moreover, the functional relationship between the two types of sleep remains the matter of much conjecture. Several questions come to mind. How does sleep regu...
journal_title：Sleep medicine
pub_type： 杂志文章,评审
doi：10.1016/j.sleep.2020.02.004
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:Rapid eye movement sleep behavior disorder (RBD) is an early feature in α synucleinopathies and may precede other clinical manifestations of disease for several years. Olfactory dysfunction and mild motor abnormalities (MMAs) are highly prevalent in prodromal α synucleinopathies such as RBD and are suspected...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2013.06.008
更新日期：2013-11-01 00:00:00
abstract：OBJECTIVE:Sleep-disordered breathing is associated with hypertension and cardiovascular disease. Increased aortic stiffness is one possible linking mechanism. We evaluated the association between sleep-disordered breathing and aortic stiffness in a community-based sample. METHODS:Our community-based cross-sectional ob...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2015.11.009
更新日期：2016-03-01 00:00:00
abstract：OBJECTIVES:To investigate factors associated with residual sleepiness in patients who were highly adherent to continuous positive airway pressure (CPAP). Nocturnal inactivity, comorbidities, concomitant medications, and, in particular, white matter (WM) differences using diffusion magnetic resonance imaging (MRI) were ...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2018.09.011
更新日期：2019-01-01 00:00:00
abstract：STUDY OBJECTIVE:We analyzed archival data from an epidemiology study to test the association between vitamin use and sleep. DESIGN:Random digit dialing was used to recruit 772 people ranging in age from 20 to 98 for a study of people's sleep experience. These individuals completed a set of questionnaires about their s...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2006.12.009
更新日期：2007-12-01 00:00:00
abstract：:Objective: To compare treatment outcomes associated with combined pharmacologic and non-pharmacologic treatments for psychophysiological insomnia.Background: Treatments for insomnia have included a variety of pharmacotherapy and cognitive-behavioral interventions, although few studies have investigated the combined ef...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/s1389-9457(00)00042-3
更新日期：2000-10-01 00:00:00
abstract：OBJECTIVE:The objective of this study is to measure the relationship between sleep quality and health-related quality of life (HRQOL), in Indian population with type 2 diabetes mellitus (T2DM). METHODS:A cross-sectional study, included a total of 300 patients with T2DM. All participants were responding to the Pittsbur...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2020.04.022
更新日期：2020-09-01 00:00:00
abstract：OBJECTIVE:Manifestations of narcolepsy with cataplexy (NC) include disturbed nocturnal sleep - hereunder sleep-wake instability, decreased latency to rapid eye movement (REM) sleep, and dissociated REM sleep events. In this study, we characterized the electroencephalography (EEG) of various sleep stages in NC versus co...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2015.09.005
更新日期：2015-12-01 00:00:00
abstract：OBJECTIVES:Arousal dysregulation has been speculated to be involved in the pathological mechanism of attention deficit/hyperactivity disorder (ADHD). However, there has been no epidemiological study assessing the real condition of excessive daytime sleepiness (EDS) in adults with ADHD. This study investigated the preva...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2016.04.008
更新日期：2017-04-01 00:00:00
abstract：BACKGROUND AND PURPOSE:We previously postulated how evolutionary changes in man's upper respiratory tract to facilitate speech, a phenomenon Jared Diamond calls The Great Leap Forward, have predisposed man to obstructive sleep apnea (OSA) [Diamond J. The Third Chimpanzee: the evolution and future of the human animal. N...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2005.03.007
更新日期：2005-11-01 00:00:00
abstract：STUDY OBJECTIVES:To examine the associations between screen time, the time spent on different screen devices, and sleep in a sample of Finnish preschool children. METHODS:The current study analyzed cross-sectional data from the DAGIS study carried out in Finland in 2015-2016 on 736 children aged 3-6 years. Parents rep...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2020.11.008
更新日期：2020-11-11 00:00:00
abstract：BACKGROUND AND PURPOSE:Although upper airway collapsibility (UAC) is theoretically useful to anticipate severity of sleep-disordered breathing (SDB), inspiratory UAC measurements are poorly correlated with obstructive sleep apnea (OSA) severity. PATIENTS AND METHODS:We investigated in 15 healthy and 35 SDB awake subje...
journal_title：Sleep medicine
pub_type： 杂志文章,多中心研究
doi：10.1016/j.sleep.2004.10.013
更新日期：2005-05-01 00:00:00
abstract：OBJECTIVES:The present study aimed to clarify the prevalence and risk factors of insomnia among public school teachers in Japan by examining the relationships between working hours, commuting time, and insomnia. Time spent on work activities among teachers with insomnia was also investigated. METHODS:This study was a ...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2019.09.017
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:Poor sleep may be associated with the cardiovascular disease (CVD) morbidity and mortality. It is less clear if poor sleep is associated with subclinical CVD. We evaluated cross-sectional associations between self-reported sleep disturbance and duration and calcification in the coronary arteries (CAC) and ao...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2012.11.016
更新日期：2013-03-01 00:00:00
