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Narcolepsy and the ability to resist sleep.

Abstract：

:We describe five patients who presented with irresistible daytime sleepiness and who have the clinical and laboratory features of narcolepsy but differ from most patients with narcolepsy in their ability to resist falling asleep during the daytime. All of the patients described partial or complete remission of their symptoms. Using an HLA marker, the expected haplotypes for narcolepsy were found, but no specific genetic features were found associated with chromosome 6p that differentiated this group from patients with typical narcolepsy. Problems are discussed in the laboratory assessment of such patients using both the multiple sleep latency test and the maintenance of wakefulness test.

journal_name

Sleep Med

journal_title

Sleep medicine

authors

Shechter-Amir D,Wade JA,Moldofsky H

doi

10.1016/s1389-9457(99)00016-7

keywords:

subject

Has Abstract

pub_date

2000-04-01 00:00:00

pages

101-108

issue

2

eissn

1389-9457

issn

1878-5506

pii

S1389-9457(99)00016-7

journal_volume

1

pub_type

杂志文章

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