Effects of atmospheric particulate matter pollution on sleep disorders and sleep duration: a cross-sectional study in the UK biobank.


BACKGROUND:Sleep disorder prevalence exhibited a six-fold relative increase from 2000 to 2010 in the United States. Sleep problems could increase the risk of stroke, cardiovascular disease, diabetes and cancer. Objective short sleep duration is associated with increased mortality. Obesity, smoking and sex differences could influence sleep disorders and sleep duration. The health effects of atmospheric particulate matter (PM) pollution are of great concern. However, a large general population-based study with abundant demographic and lifestyle information is needed to confirm the effect of PM pollution on sleep disorders and sleep duration. METHODS:Information on PM air pollution, demographics and other related factors was obtained from the UK Biobank. Subjects' characteristics were described as the means and 95% confidence intervals (95% CIs) for continuous variables and counts (percentages) for categorical variables. In the case-control study of sleep disorders, univariate analysis, single-pollutant models and a four-pollutant model with logistic regression were performed to estimate the odds ratio (OR) of the risk factors. For sleep duration, univariate analysis, single-pollutant models and a four-pollutant model with linear regressions were carried out to assess the effect of the factors. Sensitivity analysis was performed by data imputation and study population change. RESULTS:There were 5976 cases and 97,160 controls included in the case-control study of sleep disorders. For sleep duration analysis, most of the participants had environmental PM data, and 457,358 participants were selected. The single-pollutant models showed that the OR of PM2.5 for sleep disorders was 2.39 (95% CI: 1.64-3.48) for every 10 μg/m3 increase. PM2.5 and PM10 reduced sleep duration by 0.14 (95% CI: 0.10-0.18) and 0.12 (95% CI: 0.10-0.14) hours for every 10 μg/m3 increase, respectively. Four-pollutant models showed that the OR of PM2.5 for sleep disorders was 4.42 (95% CI: 2.36-8.26) for every 10 μg/m3 increase. PM10 appeared to reduce sleep duration by 0.09 (95% CI: 0.06-0.12) hours for every 10 μg/m3 increase. The main results showed good robustness after sensitivity analysis. CONCLUSIONS:PM2.5 was a risk factor for sleep disorders. PM2.5 and PM10 reduced sleep duration. A reduction in particulate matter exposure may decrease the risk of sleep disorders and improve sleep duration.


Sleep Med


Sleep medicine


Li L,Zhang W,Xie L,Jia S,Feng T,Yu H,Huang J,Qian B




Has Abstract


2020-10-01 00:00:00












  • Clinical markers of early nigrostriatal neurodegeneration in idiopathic rapid eye movement sleep behavior disorder.

    abstract:BACKGROUND:Rapid eye movement sleep behavior disorder (RBD) is an early feature in α synucleinopathies and may precede other clinical manifestations of disease for several years. Olfactory dysfunction and mild motor abnormalities (MMAs) are highly prevalent in prodromal α synucleinopathies such as RBD and are suspected...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Rupprecht S,Walther B,Gudziol H,Steenbeck J,Freesmeyer M,Witte OW,Günther A,Schwab M

    更新日期:2013-11-01 00:00:00

  • Familial aggregation and heritability of insomnia in a community-based study.

    abstract:BACKGROUND:Emerging data suggested a significant familial aggregation of insomnia. We aimed to clarify the familial aggregation and heritability of insomnia disorder by using structural clinical interviews for the ascertainment of insomnia and psychiatric disorders in a community-based sample. METHODS:Seventy-five ado...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Wing YK,Zhang J,Lam SP,Li SX,Tang NL,Lai KY,Li AM

    更新日期:2012-09-01 00:00:00

  • Altered cortical excitability in patients with untreated obstructive sleep apnea syndrome.

    abstract:OBJECTIVE:To investigate cortical excitability in patients with obstructive sleep apnea syndrome (OSAS) during wakefulness. METHODS:The authors recruited 45 untreated severe OSAS (all males, mean age 47.2 years, mean apnea-hypopnea index=44.6h(-1)) patients and 44 age-matched healthy male volunteers (mean apnea-hypopn...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Joo EY,Kim HJ,Lim YH,Koo DL,Hong SB

    更新日期:2010-10-01 00:00:00

  • Assessing health-related quality of life in patients with restless legs syndrome in Korea: comparison with other chronic medical diseases.

    abstract:BACKGROUND:There have been few quality of life (QoL) studies of patients with restless legs syndrome (RLS) in Asian countries. We studied the QoL of patients with RLS and compared it to normal controls and patients with hypertension, type 2 diabetes, or osteoarthritis in Korea. METHODS:A total of 215 RLS patients (141...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Cho YW,Kim DH,Allen RP,Earley CJ

    更新日期:2012-10-01 00:00:00

  • Feasibility of electronic sleep disorder screening in healthcare workers of a large healthcare system.

    abstract:STUDY OBJECTIVES:Many healthcare workers live with sleep disorders and may be unaware of their condition. We aimed to ascertain sleep disorder symptoms including high-risk obstructive sleep apnea (hrOSA), significant insomnia, and excessive daytime sleepiness (EDS) by work shift in a sample of healthcare workers. We ai...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Pascoe M,Alberts J,Wang L,Bruton M,Rogen B,Rehm SJ,McHugh L,Katzan I,Foldvary-Schaefer N

    更新日期:2020-09-01 00:00:00

  • Sonographic abnormalities of brainstem structures in restless legs syndrome.

    abstract:BACKGROUND AND PURPOSE:Using transcranial B-mode sonography (TCS), the first morphological marker for restless legs syndrome (RLS), hypoechogenicity of the substantia nigra (SN) has been found. The aim of this study was to validate SN hypoechogenicity as a morphological marker for RLS in a large patient cohort and to i...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Godau J,Wevers AK,Gaenslen A,Di Santo A,Liepelt I,Gasser T,Berg D

    更新日期:2008-10-01 00:00:00

  • A WASO sub-group analysis of a 6-month study of eszopiclone 3 mg.

    abstract:BACKGROUND:Insomnia marked by sleep maintenance difficulty is extremely prevalent. Yet, problems staying asleep have been relatively neglected as a research focus compared to problems falling asleep. Insomnia treatment studies typically have not required participants to have a problem specifically with sleep maintenanc...

    journal_title:Sleep medicine

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Krystal AD,Huang H,Zummo J,Grinnell T,Marshall RD

    更新日期:2012-06-01 00:00:00

  • Japanese Sleep Questionnaire for Elementary Schoolers (JSQ-ES): validation and population-based score distribution.

    abstract:OBJECTIVE:The Japanese Sleep Questionnaire for Elementary Schoolers (JSQ-ES) was developed to measure the sleep habits and disturbances of Japanese children. The current study aimed to present psychometric properties and describe the score distribution of the JSQ-ES. In addition, it examined correlations between the sl...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Kuwada A,Mohri I,Asano R,Matsuzawa S,Kato-Nishimura K,Hirata I,Mitsuhosi T,Kagitani-Shimono K,Nakanishi M,Tachibana M,Ohno Y,Taniike M

    更新日期:2018-01-01 00:00:00

  • Self-reported sleep quality is associated with gut microbiome composition in young, healthy individuals: a pilot study.

    abstract:OBJECTIVES:The microbiota-gut-brain axis is an intricate communication network that is emerging as a key modulator of psychological and physiological wellbeing. Recent pioneering work in the field has suggested a possible link between gut microbiome composition with sleep, an evolutionarily conserved behavior demonstra...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Grosicki GJ,Riemann BL,Flatt AA,Valentino T,Lustgarten MS

    更新日期:2020-09-01 00:00:00

  • Iron deficiency with normal ferritin levels in restless legs syndrome.

    abstract::This report describes a patient with iron deficiency in bone marrow examination and iron-responsive restless legs syndrome (RLS), in whom serum ferritin levels were well above the conventional cutoff for considering iron deficiency. The predictive value of serum ferritin for iron deficiency in RLS depends on the cutof...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: O'Keeffe ST

    更新日期:2005-05-01 00:00:00

  • Decreased concentration of klotho and increased concentration of FGF23 in the cerebrospinal fluid of patients with narcolepsy.

    abstract:OBJECTIVE:to explore the status of concentration of klotho and fibroblast growth factor 23 (FGF23) in cerebrospinal fluid (CSF) of patients with narcolepsy. PATIENTS/METHODS:59 patients with narcolepsy and 17 control individuals were enrolled. We used radioimmunoassay, human klotho enzyme-linked immunosorbent assay (E...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: da Paz Oliveira G,Elias RM,Peres Fernandes GB,Moyses R,Tufik S,Bichuetti DB,Coelho FMS

    更新日期:2020-12-15 00:00:00

  • Improved night shift schedule related to the mortality of critically ill patients with Corona Virus Disease 2019.

    abstract:PURPOSE:To determine the relationship between the improved night shift schedule and the mortality of critically ill patients with Corona Virus Disease 2019 (COVID-19). METHODS:According to the time of the implementation of the new night shift schedule, we divided all patients into two groups: initial period group and ...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Zhang S,Xu Y,Wu K,Wang T,Su X,Han Q,Xi Y,Zhu S,Gao Y,Wang H,Hu Y,Liu C,Zhong N,Ran P,Zhang N

    更新日期:2020-11-01 00:00:00

  • Comparison of Epworth Sleepiness Scale scores by patients with obstructive sleep apnea and their bed partners.

    abstract:OBJECTIVES:In some patients with obstructive sleep apnea (OSA), Epworth Sleepiness Scale scores (ESS) do not reflect the severity of disease. In many cases, bed partners (BPs) report more severe hypersomnia on the part of the patient than the patient him/herself. The purpose of this study was to assess the agreement be...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Walter TJ,Foldvary N,Mascha E,Dinner D,Golish J

    更新日期:2002-01-01 00:00:00

  • Clinical, polysomnographic and laboratory characteristics of narcolepsy-cataplexy in a sample of children and adolescents.

    abstract:OBJECTIVE:To report our findings from a sample of narcoleptic children and adolescents evaluated in our unit from 1988 to 2005. PATIENTS AND METHODS:The sample was composed of nine children (5 boys) with a mean age of 14.5 years at diagnosis. The protocol included the following: Epworth, Ullanlinna narcolepsy scale, a...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Peraita-Adrados R,García-Peñas JJ,Ruiz-Falcó L,Gutiérrez-Solana L,López-Esteban P,Vicario JL,Miano S,Aparicio-Meix M,Martinez-Sopena MJ

    更新日期:2011-01-01 00:00:00

  • Sleep apnea in Machado-Joseph disease: a clinical and polysomnographic evaluation.

    abstract:OBJECTIVE/BACKGROUND:Machado-Joseph disease (MJD) or spinocerebellar ataxia type 3 (SCA3) is the most common type of autosomal dominant spinocerebellar ataxia (SCA). Sleep disorders have been described as frequent non-motor symptoms in MJD, and with marked impairment on quality of life. However, few studies have evalua...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Folha Santos FA,de Carvalho LBC,Prado LFD,do Prado GF,Barsottini OG,Pedroso JL

    更新日期:2018-08-01 00:00:00

  • REM sleep behavior disorder in a patient with pontine stroke.

    abstract::Rapid eye movement (REM) sleep behavior disorder (RBD) is frequently seen in patients with neurodegenerative diseases. It can also be seen in brainstem lesions involving the pons. However, RBD in patients with a pure pontine infarction has been rarely reported. A 68-year-old man had a two-month history of violent beha...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Xi Z,Luning W

    更新日期:2009-01-01 00:00:00

  • New data on psychological traits and sleep profiles of patients affected by nocturnal eating.

    abstract:OBJECTIVE:Nocturnal eating behavior is shared by patients affected by a parasomnia, sleep-related eating disorder (SRED), and several eating disorders such as night eating syndrome (NES) and binge-eating disorder (BED); however, the differential clinical features of these patients have been poorly studied, with persist...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Vinai P,Ferri R,Anelli M,Ferini-Strambi L,Zucconi M,Oldani A,Manconi M

    更新日期:2015-06-01 00:00:00

  • Idiopathic REM sleep behavior disorder in the elderly Spanish community: a primary care center study with a two-stage design using video-polysomnography.

    abstract:OBJECTIVE:To examine the presence and characteristics of idiopathic REM sleep behavior disorder (IRBD) in a representative Caucasian sample from the elderly community of Lleida, Spain, attending primary care centers. METHODS:Participants were individuals aged 60 years or older who underwent routine visits in two prima...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Pujol M,Pujol J,Alonso T,Fuentes A,Pallerola M,Freixenet J,Barbé F,Salamero M,Santamaría J,Iranzo A

    更新日期:2017-12-01 00:00:00

  • The association between sleep-disordered breathing and aortic stiffness in a community cohort.

    abstract:OBJECTIVE:Sleep-disordered breathing is associated with hypertension and cardiovascular disease. Increased aortic stiffness is one possible linking mechanism. We evaluated the association between sleep-disordered breathing and aortic stiffness in a community-based sample. METHODS:Our community-based cross-sectional ob...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Chami HA,Vasan RS,Larson MG,Benjamin EJ,Mitchell GF,Gottlieb DJ

    更新日期:2016-03-01 00:00:00

  • Mentoring junior URM scientists to engage in sleep health disparities research: experience of the NYU PRIDE Institute.

    abstract:AIM:The aim of this study was to evaluate the National Institute of Health (NIH)-funded PRIDE Institute in Behavioral Medicine and Sleep Disorders Research at New York University (NYU) Langone Medical Center. The NYU PRIDE Institute provides intensive didactic and mentored research training to junior underrepresented m...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Jean-Louis G,Ayappa I,Rapoport D,Zizi F,Airhihenbuwa C,Okuyemi K,Ogedegbe G

    更新日期:2016-02-01 00:00:00

  • Sleep duration associated with body mass index among Chinese adults.

    abstract:OBJECTIVE:The objective of this study was to investigate the relationship between sleep duration and obesity among Chinese adults. METHODS:A community-based cross-sectional study was conducted among Chinese adults in 2008. In total, 3225 participants were selected by a multistage cluster sampling method. Self-reported...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Sun W,Huang Y,Wang Z,Yu Y,Lau A,Ali G,Huang P,Geng Y,Xu T,Shan G

    更新日期:2015-05-01 00:00:00

  • Early nighttime parental interventions and infant sleep regulation across the first year.

    abstract:BACKGROUND:Sleep quality in early life has implications for individual and family well-being [19]. Parenting in the early months may be highly influential on infant sleep patterns and trajectories. METHOD:This study used observational and survey data to investigate how sleeping arrangement and two types of nighttime i...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Voltaire ST,Teti DM

    更新日期:2018-12-01 00:00:00

  • "My child has a sleep problem": a cross-cultural comparison of parental definitions.

    abstract:BACKGROUND:Sleep problems are highly prevalent in early childhood. In many cases, parents seek professional help when they suspect their child suffers from a sleep problem. The aim of this study was to explore sleep, demographic and cultural factors associated with parental definition of child sleep problem in a large-...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Sadeh A,Mindell J,Rivera L

    更新日期:2011-05-01 00:00:00

  • Sleep and major depressive disorder: a review of non-pharmacological chronotherapeutic treatments for unipolar depression.

    abstract::Depression is a significant public health issue, made worse by the absence of response to antidepressant medications by many patients. Given the high degree of overlap between sleep and circadian complaints and depression, chronotherapies are a promising avenue for novel, effective, and fast-acting treatments for depr...

    journal_title:Sleep medicine

    pub_type: 杂志文章,评审


    authors: Cunningham JEA,Stamp JA,Shapiro CM

    更新日期:2019-09-01 00:00:00

  • An assessment of the efficacy and safety of eszopiclone in the treatment of transient insomnia in healthy adults.

    abstract:BACKGROUND AND PURPOSE:This randomized, double-blind, placebo-controlled study assessed the efficacy and safety of eszopiclone, a non-benzodiazepine hypnotic agent, in healthy adults using the first-night effect model of transient insomnia. PATIENTS AND METHODS:A total of 436 healthy, normal sleeping participants were...

    journal_title:Sleep medicine

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Rosenberg R,Caron J,Roth T,Amato D

    更新日期:2005-01-01 00:00:00

  • The APOE epsilon4 allele increases the risk of impaired spatial working memory in obstructive sleep apnea.

    abstract:BACKGROUND:Contradictory data have been published on the influence of Apolipoprotein E (APOE) epsilon4 allele on obstructive sleep apnea (OSA). The aims of this study were to confirm the presence of specific neuropsychological changes in OSA patients carrying the APOE epsilon4 allele and to clarify if these changes are...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Cosentino FI,Bosco P,Drago V,Prestianni G,Lanuzza B,Iero I,Tripodi M,Spada RS,Toscano G,Caraci F,Ferri R

    更新日期:2008-12-01 00:00:00

  • Cholinergic neurotransmission and olfactory function in obstructive sleep apnea syndrome: a TMS study.

    abstract:BACKGROUND/OBJECTIVE:Odor identification and discrimination are reduced in subjects with obstructive sleep apnea syndrome (OSAS), but the pathophysiology of the olfactory dysfunction in OSAS is still poorly understood. Experimental evidence suggests that olfactory impairment could be related to central cholinergic dysf...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Versace V,Langthaler PB,Sebastianelli L,Golaszewski S,Kunz AB,Brigo F,Saltuari L,Nardone R

    更新日期:2017-09-01 00:00:00

  • Mechanisms influencing older adolescents' bedtimes during videogaming: the roles of game difficulty and flow.

    abstract::A relationship between evening technology use and sleep has been established, and models suggest various mechanisms to explain this relationship. Recent updates to these models also suggest the influence of individual difference factors, such that the relationship between technology and sleep varies between young peop...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Smith LJ,King DL,Richardson C,Roane BM,Gradisar M

    更新日期:2017-11-01 00:00:00

  • Protective and risk factors associated with adolescent sleep: findings from Australia, Canada, and The Netherlands.

    abstract:BACKGROUND:Sleep is vital for adolescent functioning. Those with optimal sleep duration have shown improved capacity to learn and decreased rate of motor vehicle accidents. This study explored the influence of numerous protective and risk factors on adolescents' school night sleep (bedtime, sleep latency, total sleep t...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Bartel K,Williamson P,van Maanen A,Cassoff J,Meijer AM,Oort F,Knäuper B,Gruber R,Gradisar M

    更新日期:2016-10-01 00:00:00

  • Prevalence and correlates of delayed sleep phase in high school students.

    abstract:PURPOSE:To investigate prevalence and correlates of delayed sleep phase, characterized by problems falling asleep in the evening and rising at adequate times in the morning, in a large sample of Norwegian high school students. METHODS:A randomized sample of 1285 high school students (aged 16-19 years) participated in ...

    journal_title:Sleep medicine

    pub_type: 杂志文章


    authors: Saxvig IW,Pallesen S,Wilhelmsen-Langeland A,Molde H,Bjorvatn B

    更新日期:2012-02-01 00:00:00